A novel type of co‐chaperone mediates transmembrane recruitment of DnaK‐like chaperones to ribosomes

No abstract is available for this paper.

• Publication year

  2002

• Venue

  EMBO Journal

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1093/emboj/cdf422cPMID 12065409PMCID PMC126068
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phloem-restricted trypanosomatids form a clearly characterised monophyletic group among trypanosomatids isolated from plants.

  2001cited by this paper
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  2001cited by this paper
• Sec63p and Kar2p are required for the translocation of SRP‐dependent precursors into the yeast endoplasmic reticulum in vivo

  2001cited by this paper
• Interaction of Murine BiP/GRP78 with the DnaJ Homologue MTJ1*

  2000cited by this paper
• Homologs of the yeast Sec complex subunits Sec62p and Sec63p are abundant proteins in dog pancreas microsomes.

  2000cited by this paper
• Mammalian Sec61 Is Associated with Sec62 and Sec63*

  2000cited by this paper
• Molecular Characterization of a Novel Mammalian DnaJ-Like Sec63p Homolog

  1999cited by this paper
• Interaction of BiP with the J-domain of the Sec63p Component of the Endoplasmic Reticulum Protein Translocation Complex*

  1999cited by this paper
• Phosphorylation by CK2 and MAPK enhances calnexin association with ribosomes

  1999cited by this paper
• Intracellular localization and in vivo trafficking of p24A and p23.

  1999cited by this paper
• A Scj1p Homolog and Folding Catalysts Present in Dog Pancreas Microsomes

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• Zuotin, a ribosome‐associated DnaJ molecular chaperone

  1998cited by this paper
• BiP maintains the permeability barrier of the ER membrane by sealing the lumenal end of the translocon pore before and early in translocation.

  1998cited by this paper
• Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

  1997cited by this paper
• The Yeast JEM1p Is a DnaJ-like Protein of the Endoplasmic Reticulum Membrane Required for Nuclear Fusion*

  1997cited by this paper
• Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration.

  1997cited by this paper
• Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation

  1997cited by this paper
• Binding of secretory precursor polypeptides to a translocon subcomplex is regulated by BiP.

  1997cited by this paper
• The Lumenal Domain of Sec63p Stimulates the ATPase Activity of BiP and Mediates BiP Recruitment to the Translocon in Saccharomyces cerevisiae

  1997cited by this paper
• Mechanism of Polypeptide Translocation into the Endoplasmic Reticulum*

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• Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

  1996cited by this paper
• Analysis of a 36·2 kb DNA sequence including the right telomere of chromosome VI from Saccharomyces cerevisiae

  1996cited by this paper
• Oligomeric rings of the Sec61p complex induced by ligands required for protein translocation.

  1996cited by this paper
• Cer1p, a Novel Hsp70-related Protein Required for Posttranslational Endoplasmic Reticulum Translocation in Yeast*

  1996cited by this paper
• A novel Hsp70 of the yeast ER lumen is required for the efficient translocation of a number of protein precursors.

  1996cited by this paper
• SSI1 encodes a novel Hsp70 of the Saccharomyces cerevisiae endoplasmic reticulum

  1996cited by this paper
• A microsomal ATP‐binding protein involved in efficient protein transport into the mammalian endoplasmic reticulum.

  1996cited by this paper
• Interaction between BiP and Sec63p is required for the completion of protein translocation into the ER of Saccharomyces cerevisiae

  1995cited by this paper
• Isolation of a mouse cDNA encoding MTJ1, a new murine member of the DnaJ family of proteins.

  1995cited by this paper
• BiP and Sec63p are required for both co- and posttranslational protein translocation into the yeast endoplasmic reticulum.

  1995cited by this paper
• Molecular chaperones involved in protein degradation in the endoplasmic reticulum: quantitative interaction of the heat shock cognate protein BiP with partially folded immunoglobulin light chains that are degraded in the endoplasmic reticulum.

  1995cited by this paper
• A yeast DnaJ homologue, Scj1p, can function in the endoplasmic reticulum with BiP/Kar2p via a conserved domain that specifies interactions with Hsp70s

  1995cited by this paper
• Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p.

  1995cited by this paper
• Evolutionary conservation of components of the protein translocation complex

  1994cited by this paper
• Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane.

  1993cited by this paper
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• Mutants in three novel complementation groups inhibit membrane protein insertion into and soluble protein translocation across the endoplasmic reticulum membrane of Saccharomyces cerevisiae

  1992cited by this paper
• Sec61p and BiP directly facilitate polypeptide translocation into the ER.

  1992cited by this paper
• A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation.

  1992cited by this paper
• Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex

  1991cited by this paper
• Binding protein BiP is required for translocation of secretory proteins into the endoplasmic reticulum in Saccharomyces cerevisiae.

  1991cited by this paper
• Loss of BiP/GRP78 function blocks translocation of secretory proteins in yeast

  1990cited by this paper
• A yeast gene important for protein assembly into the endoplasmic reticulum and the nucleus has homology to DnaJ, an Escherichia coli heat shock protein

  1989cited by this paper
• Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast

  1989cited by this paper
• SEC62 encodes a putative membrane protein required for protein translocation into the yeast endoplasmic reticulum

  1989cited by this paper
• In vivo and in vitro analysis of ptl1, a yeast ts mutant with a membrane‐associated defect in protein translocation.

  1988cited by this paper
• A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum

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