Anti-loxoscelic horse serum produced against a recombinant dermonecrotic protein of Brazilian Loxosceles intermedia spider neutralize lethal effects of Loxosceles laeta venom from Peru.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Toxicon

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.toxicon.2014.10.023PMID 25448393
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Innovative immunization protocols using chimeric recombinant protein for the production of polyspecific loxoscelic antivenom in horses.

  2014cited by this paper
• Biochemical and immunological characteristics of Peruvian Loxosceles laeta spider venom: neutralization of its toxic effects by anti-loxoscelic antivenoms.

  2013cited by this paper
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  2007cited by this paper
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  2005cited by this paper
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  2004cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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• [Poisoning by spiders of Loxosceles genus].

  2002cited by this paper
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  1998cited by this paper
• Loxoscelism.

  1992cited by this paper
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  1979cited by this paper
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  1976cited by this paper
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  1970cited by this paper

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