Neuroadapted Yellow Fever Virus 17D: Genetic and Biological Characterization of a Highly Mouse-Neurovirulent Virus and Its Infectious Molecular Clone

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Journal of Virology

• Publication date

  2001-11-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JVI.75.22.10912-10922.2001PMID 11602731PMCID PMC114671
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Yellow fever vaccine

  2017cited by this paper
• Loss of active neuroinvasiveness in attenuated strains of West Nile virus: pathogenicity in immunocompetent and SCID mice

  2005cited by this paper
• A novel model for the study of the therapy of flavivirus infections using the Modoc virus.

  2001cited by this paper
• Biophysical Characterization and Vector-Specific Antagonist Activity of Domain III of the Tick-Borne Flavivirus Envelope Protein

  2001cited by this paper
• Molecular Basis for Attenuation of Neurovirulence of a Yellow Fever Virus/Japanese Encephalitis Virus Chimera Vaccine (ChimeriVax-JE)

  2001cited by this paper
• Attenuation Markers of a Candidate Dengue Type 2 Vaccine Virus, Strain 16681 (PDK-53), Are Defined by Mutations in the 5′ Noncoding Region and Nonstructural Proteins 1 and 3

  2000cited by this paper
• Modulation of Dengue Virus Infection in Human Cells by Alpha, Beta, and Gamma Interferons

  2000cited by this paper
• Determinants in the envelope E protein and viral RNA helicase NS3 that influence the induction of apoptosis in response to infection with dengue type 1 virus.

  2000cited by this paper
• Interaction of Yellow Fever Virus French Neurotropic Vaccine Strain with Monkey Brain: Characterization of Monkey Brain Membrane Receptor Escape Variants

  2000cited by this paper
• Attenuation of Tick-Borne Encephalitis Virus by Structure-Based Site-Specific Mutagenesis of a Putative Flavivirus Receptor Binding Site

  2000cited by this paper
• Infectious cDNA clones of Langat tick-borne flavivirus that differ from their parent in peripheral neurovirulence.

  2000cited by this paper
• Immunogenicity, genetic stability, and protective efficacy of a recombinant, chimeric yellow fever-Japanese encephalitis virus (ChimeriVax-JE) as a live, attenuated vaccine candidate against Japanese encephalitis.

  1999cited by this paper
• Yellow Fever/Japanese Encephalitis Chimeric Viruses: Construction and Biological Properties

  1999cited by this paper
• New Mouse Model for Dengue Virus Vaccine Testing

  1999cited by this paper
• The Severity of Murray Valley Encephalitis in Mice Is Linked to Neutrophil Infiltration and Inducible Nitric Oxide Synthase Activity in the Central Nervous System

  1999cited by this paper
• Mutagenesis of the RGD motif in the yellow fever virus 17D envelope protein.

  1999cited by this paper
• Molecular and biological changes associated with HeLa cell attenuation of wild-type yellow fever virus.

  1999cited by this paper
• Mapping of Functional Elements in the Stem-Anchor Region of Tick-Borne Encephalitis Virus Envelope Protein E

  1999cited by this paper
• Apoptosis in the Mouse Central Nervous System in Response to Infection with Mouse-Neurovirulent Dengue Viruses

  1998cited by this paper
• Attenuation of Japanese encephalitis virus by selection of its mouse brain membrane receptor preparation escape variants.

  1998cited by this paper
• Genetic Determinants Responsible for Acquisition of Dengue Type 2 Virus Mouse Neurovirulence

  1998cited by this paper
• Mutation in a 17D-204 vaccine substrain-specific envelope protein epitope alters the pathogenesis of yellow fever virus in mice.

  1998cited by this paper
• Spontaneous and Engineered Deletions in the 3′ Noncoding Region of Tick-Borne Encephalitis Virus: Construction of Highly Attenuated Mutants of a Flavivirus

  1998cited by this paper
• Secondary structure of the 3'-untranslated region of yellow fever virus: implications for virulence, attenuation and vaccine development.

  1997cited by this paper
• The molecular basis of virulence of the encephalitogenic flaviviruses.

  1997cited by this paper
• Yellow fever virus envelope protein has two discrete type-specific neutralizing epitopes.

  1997cited by this paper
• Antigenic variants of yellow fever virus with an altered neurovirulence phenotype in mice.

  1997cited by this paper
• Molecular differences between wild-type Japanese encephalitis virus strains of high and low mouse neuroinvasiveness.

  1996cited by this paper
• Dengue type 4 virus mutants containing deletions in the 3' noncoding region of the RNA genome: analysis of growth restriction in cell culture and altered viremia pattern and immunogenicity in rhesus monkeys

  1996cited by this paper
• Structural requirements for low-pH-induced rearrangements in the envelope glycoprotein of tick-borne encephalitis virus

  1996cited by this paper
• A mouse-attenuated envelope protein variant of Murray Valley encephalitis virus with altered fusion activity.

  1996cited by this paper
• Replication of yellow fever virus in the mouse central nervous system: comparison of neuroadapted and non-neuroadapted virus and partial sequence analysis of the neuroadapted strain.

  1996cited by this paper
• Mutagenesis of the N-linked glycosylation sites of the yellow fever virus NS1 protein: effects on virus replication and mouse neurovirulence.

  1996cited by this paper
• Murray valley encephalitis virus envelope protein antigenic variants with altered hemagglutination properties and reduced neuroinvasiveness in mice.

  1995cited by this paper
• The envelope glycoprotein from tick-borne encephalitis virus at 2 Å resolution

  1995cited by this paper
• Phenotypic analysis of yellow fever virus derived from complementary DNA.

  1995cited by this paper
• Oligomeric rearrangement of tick-borne encephalitis virus envelope proteins induced by an acidic pH

  1995cited by this paper
• Characterization of a highly attenuated Japanese encephalitis virus generated from molecularly cloned cDNA.

  1995cited by this paper
• Comparison of the genomes of the wild-type French viscerotropic strain of yellow fever virus with its vaccine derivative French neurotropic vaccine.

  1995cited by this paper
• Yellow fever and dengue—the interactions of virus, vector and host in the re-emergence of epidemic disease

  1994cited by this paper
• Analysis of a yellow fever virus isolated from a fatal case of vaccine-associated human encephalitis.

  1994cited by this paper
• Structural changes and functional control of the tick-borne encephalitis virus glycoprotein E by the heterodimeric association with protein prM.

  1994cited by this paper
• Genetic determinants of dengue type 4 virus neurovirulence for mice

  1993cited by this paper
• Molecular analysis of neurovirulent strains of Sindbis virus that evolve during persistent infection of scid mice

  1993cited by this paper
• Comparison of the nucleotide and deduced amino acid sequences of the envelope protein genes of the wild-type French viscerotropic strain of yellow fever virus and the live vaccine strain, French neurotropic vaccine, derived from it.

  1993cited by this paper
• Chimeric tick-borne encephalitis and dengue type 4 viruses: effects of mutations on neurovirulence in mice

  1993cited by this paper
• Viral neuroinvasion and encephalitis induced by lipopolysaccharide and its mediators

  1992cited by this paper
• Mutations in the envelope protein of Japanese encephalitis virus affect entry into cultured cells and virulence in mice.

  1992cited by this paper
• Host cell selection of Murray Valley encephalitis virus variants altered at an RGD sequence in the envelope protein and in mouse virulence.

  1990cited by this paper
• Transcription of infectious yellow fever RNA from full-length cDNA templates produced by in vitro ligation.

  1989cited by this paper
• Comparison of the virulent Asibi strain of yellow fever virus with the 17D vaccine strain derived from it.

  1987cited by this paper
• Comparison of neurovirulence of different strains of yellow fever virus in mice.

  1986cited by this paper
• Pathobiology of the Flaviviruses

  1986cited by this paper
• Nucleotide sequence of yellow fever virus: implications for flavivirus gene expression and evolution.

  1985cited by this paper
• Isolation of plaque variants differing in virulence from the 17D strain of yellow fever virus.

  1981cited by this paper
• 4 – Virus–Host Interactions in Natural and Experimental Infections with Alphaviruses and Flaviviruses

  1980cited by this paper
• Variation in virulence for mice and rhesus monkeys among St. Louis encephalitis virus strains of different origin.

  1980cited by this paper
• The in vivo differentiation of strains of yellow fever virus in mice.

  1980cited by this paper
• Role of macrophages and antibody in resistance of mice against yellow fever virus.

  1971cited by this paper
• Effects of thorotrast on humoral antibody, viral multiplication, and interferon during infection with St. Louis encephalitis virus in mice.

  1971cited by this paper
• Adaptation of the 17D yellow fever virus to mouse brain by serial passage

  1959cited by this paper
• The Virus

  1940cited by this paper
• ON YELLOW FEVER.

  1878cited by this paper

• Parallel Multifactorial Process Optimization and Intensification for High-Yield Production of Live YF17D-Vectored Zika Vaccine

  2024cites this paper
• Age-dependent Powassan virus lethality is linked to glial cell activation and divergent neuroinflammatory cytokine responses in a murine model

  2024cites this paper
• Age-dependent Powassan Virus Lethality is Directed by Glial Cell Activation and Divergent Neuroinflammatory Cytokine Responses in a Murine Model

  2023cites this paper
• Biological Characterization of Yellow Fever Viruses Isolated From Non-human Primates in Brazil With Distinct Genomic Landscapes

  2022cites this paper
• Impact of yellow fever virus envelope protein on wild-type and vaccine epitopes and tissue tropism

  2022cites this paper
• Impact of yellow fever virus envelope protein on wild-type and vaccine epitopes and tissue tropism

  2022cites this paper
• The key amino acids of E protein involved in early flavivirus infection: viral entry

  2021cites this paper
• Characteristics of Chimeric West Nile Virus Based on the Japanese Encephalitis Virus SA14-14-2 Backbone

  2021cites this paper
• Structure–Function of the Yellow Fever Virus Envelope Protein: Analysis of Antibody Epitopes

  2020cites this paper
• Consumptive coagulopathy of severe yellow fever occurs independently of hepatocellular tropism and massive hepatic injury

  2020cites this paper
• Molecular Determinants of West Nile Virus Virulence and Pathogenesis in Vertebrate and Invertebrate Hosts

  2020cites this paper
• Characterization of Plaque Variants and the Involvement of Quasi-Species in a Population of EV-A71

  2020cites this paper
• Yellow Fever: Integrating Current Knowledge with Technological Innovations to Identify Strategies for Controlling a Re-Emerging Virus

  2019cites this paper
• The Trend Analysis and Quality Evaluation of Live Attenuated Yellow Fever Vaccine in China from 2011 to 2018

  2019cites this paper
• Limited evolution of the yellow fever virus 17d in a mouse infection model

  2019cites this paper
• Growth Kinetics of Kyasanur Forest Disease Virus in Mammalian Cell Lines and Development of Plaque Reduction Neutralization Test

  2019cites this paper
• Research advancements in the neurological presentation of flaviviruses

  2018cites this paper
• Gamma-Interferon Attenuates Yellow Fever Virus Vaccine Strain 17D

  2018cites this paper
• 63 – Yellow Fever Vaccines

  2018cites this paper
• Yellow fever virus: genetic and phenotypic diversity and implications for detection, prevention and therapy.

  2015influential citation
• Phylogenetic and virulence analysis of tick‐borne encephalitis virus field isolates from Switzerland

  2011cites this paper
• ESTRATÉGIAS MOLECULARES PARA UTILIZACÃO DO VÍRUS DA FEBRE AMARELA COMO VETOR VACINAL

  2011cites this paper
• Characterisation of the immune response after yellow fever vaccination

  2011cites this paper
• Amino acid changes within the E protein hinge region that affect dengue virus type 2 infectivity and fusion.

  2011influential citation
• Nucleic Acid-Based Infectious and Pseudo-Infectious Flavivirus Vaccines

  2011cites this paper
• Pós-Graduação em Biologia Celular e Molecular

  2011cites this paper
• West Nile virus and its emergence in the United States of America

  2010cites this paper
• E Protein Domain III Determinants of Yellow Fever Virus 17D Vaccine Strain Enhance Binding to Glycosaminoglycans, Impede Virus Spread, and Attenuate Virulence

  2008cites this paper
• Pathophysiology of Abroviral Encephalitides in Laboratory Rodents

  2008cites this paper
• Molecular characterization of South African lineage II West Nile virus isolates and development of a diagnostic assay.

  2008cites this paper
• Neuroadapted Yellow Fever Virus Strain 17D: a Charged Locus in Domain III of the E Protein Governs Heparin Binding Activity and Neuroinvasiveness in the SCID Mouse Model

  2008cites this paper
• Characterization of a small plaque variant of West Nile virus isolated in New York in 2000.

  2007cites this paper
• Understanding the role of innate immunity in the mechanism of action of the live attenuated Yellow Fever Vaccine 17D.

  2007cites this paper
• Genetic Determinants of Sindbis Virus Mosquito Infection Are Associated with a Highly Conserved Alphavirus and Flavivirus Envelope Sequence

  2007cites this paper
• Evolution of the host range of the bacteriophage p6

  2007cites this paper
• New Treatment Strategies for Dengue and Other Flaviviral Diseases

  2006cites this paper
• Host-cell interaction of attenuated and wild-type strains of yellow fever virus can be differentiated at early stages of hepatocyte infection.

  2006cites this paper
• Identification of epitopes on the Dengue virus type 4 envelope glycoprotein involved in neutralisation by antibodies

  2006cites this paper
• Yellow fever vaccine

  2005cites this paper
• Yellow fever vaccine

  2005cites this paper
• Rodent models for the study of therapy against flavivirus infections.

  2004cites this paper
• Pathogenesis of flavivirus encephalitis

  2004cites this paper
• Construction of yellow fever/St. Louis encephalitis chimeric virus and the use of chimeras as a diagnostic tool.

  2004cites this paper
• ChimeriVax-West Nile Virus Live-Attenuated Vaccine: Preclinical Evaluation of Safety, Immunogenicity, and Efficacy

  2004cites this paper
• Molecular determinants of virulence: the structural and functional basis for flavivirus attenuation.

  2003cites this paper
• Pathogenesis and pathophysiology of yellow fever.

  2003cites this paper
• Neuroadapted Yellow Fever Virus 17D: Determinants in the Envelope Protein Govern Neuroinvasiveness for SCID Mice

  2003cites this paper
• Prospects for antiviral therapy.

  2003cites this paper
• Disease consequences of pathogen adaptation.

  2002cites this paper
• Infection of SCID mice with Montana Myotis leukoencephalitis virus as a model for flavivirus encephalitis.

  2002influential citation