Complementary DNA for human glioblastoma‐derived T cell suppressor factor, a novel member of the transforming growth factor‐beta gene family.

No abstract is available for this paper.

• Publication year

  1987

• Venue

  EMBO Journal

• Publication date

  1987-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/j.1460-2075.1987.tb02700.xPMID 3322813PMCID PMC553836
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Evidence that transforming growth factor-beta is a hormonally regulated negative growth factor in human breast cancer cells.

  1987cited by this paper
• Cartilage-inducing factor-B is a unique protein structurally and functionally related to transforming growth factor-beta.

  1987cited by this paper
• T cell suppressor factor from human glioblastoma cells is a 12.5‐kd protein closely related to transforming growth factor‐beta.

  1987cited by this paper
• A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family

  1987cited by this paper
• Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes.

  1986cited by this paper
• Peptide growth factors and inflammation, tissue repair, and cancer.

  1986cited by this paper
• Transforming growth factor beta is an important immunomodulatory protein for human B lymphocytes.

  1986cited by this paper
• The murine transforming growth factor-beta precursor.

  1986cited by this paper
• Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth

  1986cited by this paper
• Transforming growth factor-beta: biological function and chemical structure.

  1986cited by this paper
• Functional properties of tumor-infiltrating and blood lymphocytes in patients with solid tumors: effects of tumor cells and their supernatants on proliferative responses of lymphocytes.

  1986cited by this paper
• Isolation of the bovine and human genes for Müllerian inhibiting substance and expression of the human gene in animal cells.

  1986cited by this paper
• Signal sequences. The limits of variation.

  1985cited by this paper
• Complementary DNA sequences of ovarian follicular fluid inhibin show precursor structure and homology with transforming growth factor-β

  1985cited by this paper
• Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

  1985cited by this paper
• Partial purification and biochemical characterization of a T cell suppressor factor produced by human glioblastoma cells.

  1985cited by this paper
• Note added in proof

  1984cited by this paper
• Growth inhibitor from BSC-1 cells closely related to platelet type beta transforming growth factor.

  1984cited by this paper
• Glioblastoma cells release interleukin 1 and factors inhibiting interleukin 2-mediated effects.

  1984cited by this paper
• Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing.

  1984cited by this paper
• A simple and very efficient method for generating cDNA libraries.

  1983cited by this paper
• Comparison of intra- and extracellular transforming growth factors from nontransformed and chemically transformed mouse embryo cells.

  1983cited by this paper
• Presence of immunosuppressive factors in brain-tumor cyst fluid.

  1983cited by this paper
• The ovalbumin gene family: hormonal control of X and Y gene transcription and mRNA accumulation.

  1981cited by this paper
• New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.

  1981cited by this paper
• Purification of kidney epithelial cell growth inhibitors.

  1980cited by this paper
• Immunobiology of primary intracranial tumours. III. Demonstration of a qualitative lymphocyte abnormality in patients with primary brain tumours.

  1980cited by this paper
• DNA sequencing with chain-terminating inhibitors.

  1977cited by this paper
• DEPRESSED CELL-MEDIATED IMMUNITY IN PATIENTS WITH PRIMARY INTRACRANIAL TUMORS

  1972cited by this paper

• Within and beyond the tumor: Mechanisms of glioblastoma-induced immunosuppression

  2025cites this paper
• Phase 1b/2 study evaluating safety, efficacy and immune effects of TLR9 agonist cavrotolimod with anti-PD-1 antibodies among patients with advanced solid tumors

  2025cites this paper
• Regulation of Inflammatory Lung Injury by Transforming Growth Factors.

  2025cites this paper
• Transforming growth factor beta signaling and craniofacial development: modeling human diseases in zebrafish

  2024cites this paper
• The Role of Cellular Immunity and Adaptive Immunity in Pathophysiology of Brain and Spinal Cord Tumors.

  2023cites this paper
• Orphan nuclear receptor ERRγ regulates hepatic TGF-β2 expression and fibrogenic response in CCl4-induced acute liver injury

  2021cites this paper
• Immunometabolic targeting of NK cells to solid tumors

  2021cites this paper
• TGF-β links glycolysis and immunosuppression in glioblastoma.

  2021cites this paper
• Characterization of an endoplasmic reticulum stress‐related signature to evaluate immune features and predict prognosis in glioma

  2021cites this paper
• TGF‐β signaling: A recap of SMAD‐independent and SMAD‐dependent pathways

  2021cites this paper
• Overview of General and Discriminating Markers of Differential Microglia Phenotypes

  2020cites this paper
• NNT-AS1 Impairs CD4+ T Cells Infiltration by Up-Regulating TGF-β Signaling in Hepatocellular Carcinoma

  2020cites this paper
• Transforming growth factor-β and skeletal homeostasis

  2020cites this paper
• Overexpression of NNT-AS1 Activates TGF-β Signaling to Decrease Tumor CD4 Lymphocyte Infiltration in Hepatocellular Carcinoma

  2020cites this paper
• Accompagnement vers l'emploi

  2020cites this paper
• Human transforming growth factor beta2 in a tetragonal crystal form

  2019cites this paper
• Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor β2 in a new conformation

  2019cites this paper
• Allergen-induced asthma, chronic rhinosinusitis and transforming growth factor-β superfamily signaling: mechanisms and functional consequences

  2019cites this paper
• SYNDICAT SUD SANTE SOCIAUX 35

  2019cites this paper
• Transforming growth factor-β in stem cells and tissue homeostasis

  2018cites this paper
• Engineered T Cells for glioblastoma therapy

  2018influential citation
• MMP-7 is Required for TGF-β and EGF Induced Migration and Invasion in Prostate Cancer Cells

  2018cites this paper
• TGF-β2 abundance in mice and men:A successful anti-TGF-β2 strategy in biliary-derived liver disease

  2018cites this paper
• Extrahepatic Upregulation of Transforming Growth Factor Beta 2 in HCV Genotype 4-Induced Liver Fibrosis

  2018cites this paper
• TGF-β2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism

  2018cites this paper
• Importance of immune monitoring approaches and the use of immune checkpoints for the treatment of diffuse intrinsic pontine glioma: From bench to clinic and vice versa (Review)

  2018cites this paper
• Differential expression of TGFβ isoforms in breast cancer highlights different roles during breast cancer progression

  2018cites this paper
• 18 Cellular Immunotherapy for Malignant Brain Tumors

  2018cites this paper
• A Novel Role for SLK in Transforming Growth Factor-Beta-Mediated Epithelial-to-Mesenchymal Transition

  2017cites this paper
• Novel approaches in the treatment for glioblastoma multiforme

  2017cites this paper
• TGF-β1 and TGF-β2 abundance in liver diseases of mice and men

  2016cites this paper
• The Discovery and Early Days of TGF-β: A Historical Perspective.

  2016cites this paper
• Principles of immunotherapy.

  2016cites this paper
• TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology.

  2016cites this paper
• Immunosuppressive mechanisms in glioblastoma.

  2015cites this paper
• Role of TGF-β3 in the regulation of immune responses.

  2015cites this paper
• Development and characterization of human monoclonal antibodies that neutralize multiple TGFβ isoforms

  2015cites this paper
• Regulation of Hematopoietic Stem Cells

  2014cites this paper
• Characterization of Distinct Immunophenotypes across Pediatric Brain Tumor Types

  2013cites this paper
• Journal of Biotechnology Research Center Vol.7 No.1

  2013cites this paper
• Co-Localization of Transforming Growth Factor , 2 with c 1 ( I ) Procollagen mRNA in Tissue Sections of Patients with Systemic Sclerosis

  2013cites this paper
• This information is current as Tumor Types Immunophenotypes across Pediatric Brain Characterization of Distinct

  2013cites this paper
• Reversal of thyroid dedifferentiation and an invasive phenotype by small molecule kinase inhibitors: an experimental study on normal and malignant cells

  2013cites this paper
• Mechanisms of immune evasion by gliomas.

  2012cites this paper
• TGF-β – an excellent servant but a bad master

  2012cites this paper
• Cancer immunoediting in malignant glioma.

  2012cites this paper
• Regulation Of Myometrial Gene Expression By Oestrogen And Progesterone: The Use Of A Cell Culture Model To Mimic The In Vivo Conditions Of Pregnant Human Uterus

  2012cites this paper
• The paradoxical TGF-β vasculopathies

  2012cites this paper
• Clinical trials with immunotherapy for high-grade glioma.

  2012cites this paper
• Structural Requirements for Interaction of Peroxisomal Targeting Signal 2 and Its Receptor PEX7*

  2011cites this paper
• Transforming growth factor-β1 variant Leu10Pro is associated with both lack of microfilariae and differential microfilarial loads in the blood of persons infected with lymphatic filariasis.

  2011cites this paper
• TGF-β2 signaling in high-grade gliomas.

  2011cites this paper
• Challenges in Immunotherapy Presented by the Glioblastoma Multiforme Microenvironment

  2011cites this paper
• ALK1 et BMP9 dans le remodelage vasculaire de la génétique humaine aux modèles murins

  2011cites this paper
• Cellular Immunotherapy for Malignant Brain Tumors

  2011cites this paper
• Comparison of angiotensin converting enzyme inhibitors and angiotensin II type 1 receptor blockade for the prevention of premalignant changes in the liver.

  2011cites this paper
• Effect of oxygen on tumor cell vaccine.

  2010cites this paper
• Transforming Growth Factor-β1 Bioassay Involving Matrix Metalloproteinase-2 Induction

  2010cites this paper
• Effect of Oxygen on Tumor Cell Vaccine

  2010cites this paper
• Identification of a novel transforming growth factor-β (TGF-β6) gene in fish: regulation in skeletal muscle by nutritional state

  2010cites this paper
• Ginger ingredients inhibit the development of diethylnitrosoamine induced premalignant phenotype in rat chemical hepatocarcinogenesis model

  2010cites this paper
• Challenges in clinical design of immunotherapy trials for malignant glioma.

  2010cites this paper
• Hepatitis C virus core protein triggers hepatic angiogenesis by a mechanism including multiple pathways

  2009cites this paper
• Site-specific anti-tumor immunity : differences in DC function , TGF-production and numbers of intratumoral Foxp 3 + regulatory T cells

  2009cites this paper
• The PEPvIII-KLH (CDX-110) vaccine in glioblastoma multiforme patients

  2009cites this paper
• Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-β and STAT3 activation

  2009cites this paper
• Site‐specific anti‐tumor immunity: Differences in DC function, TGF‐β production and numbers of intratumoral Foxp3+ Treg

  2009cites this paper
• Transforming growth factor-beta2 is a molecular determinant for site-specific melanoma metastasis in the brain.

  2009cites this paper
• Immunotherapeutic approaches for glioma.

  2009cites this paper
• THE ROLE OF BMP SIGNALING AND ENDOGLIN IN REGULATION OF HEMATOPOIESIS

  2009cites this paper
• Lysosomotropic drugs inhibit maturation of transforming growth factor-beta.

  2008cites this paper
• 590 HEPATITIS C VIRUS (HCV) CORE PROTEIN TRIGGERS HEPATIC ANGIOGENESIS BY A MECHANISM INCLUDING MULTIPLE PATHWAYS

  2008cites this paper
• Tumor Suppressor and Pro-progression Roles for TGF-β in Breast Cancer

  2008cites this paper
• Tumor-specific immunotherapy targeting the EGFRvIII mutation in patients with malignant glioma.

  2008cites this paper
• Identification of a Novel Member (GDF-1) of the Transforming Growth Factor-/? Superfamily

  2008cites this paper
• Using guinea pigs in studies relevant to asthma and COPD.

  2008cites this paper
• Targeted Downregulation of TGF-β2 with AP 12009 in Tumor Therapy

  2008cites this paper
• Immunotherapy of malignant brain tumors

  2008cites this paper
• Growth Factor-ƒÀ Complex in Arteriovenous Malformations

  2008cites this paper
• Inhibition of the TGF-β Signaling Pathway in Tumor Cells

  2007cites this paper
• Melanoma-Associated Expression of Transforming Growth Factor-f3 Isoforms

  2007cites this paper
• Inhibition of the TGF-beta signaling pathway in tumor cells.

  2007cites this paper
• Transforming growth factor-β1 and disorders of the lung

  2007cites this paper
• Spatial and Temporal Patterns of Immunoreactive Transforming Growth Factor f31, 132, and f33 during Excisional Wound Repair

  2007cites this paper
• Protein Acetylation – A Multifunctional Regulator of TGF

  2007cites this paper
• Inhibiting TGF-beta signaling restores immune surveillance in the SMA-560 glioma model.

  2007cites this paper
• Bacterial Meningitis: The Role of Transforming Growth Factor-Beta in Innate Immunity and Secondary Brain Damage

  2007cites this paper
• The effect of the TGF-β isoforms on progenitor cell recruitment and differentiation into cardiac and skeletal muscle

  2007cites this paper
• Rapid Communication Transforming Growth Factors 1 and 2 Are Differentially Expressed in Fibrotic Liver Disease

  2007cites this paper
• Patients with Malignant Glioma CD 4 Compartment Explains Cellular Immune Defects in Increased Regulatory T-Cell Fraction Amidst a Diminished

  2006cites this paper
• 6 Transforming Growth Factor-b si n the Brain

  2006cites this paper
• A Sequential Scanning of the Immune Efficiency in Astrocytoma (Grade I to Grade III), Meningioma and Secondary Glioma Patients with and without Therapeutic Scheduling

  2006cites this paper
• TGF-beta: its role in asthma and therapeutic potential.

  2006cites this paper
• AURKA is one of the downstream targets of MAPK1/ERK2 in pancreatic cancer

  2006cites this paper
• Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma.

  2006cites this paper
• Relative Quantitation of Protein–Protein Interaction Strength Within the Yeast Two-Hybrid System via Fluorescence β-Galactosidase Activity Detection in a High-Throughput and Low-Cost Manner

  2006cites this paper
• Transforming Growth Factor-βs in the Brain

  2006cites this paper
• Cellular immunity of patients with malignant glioma: prerequisites for dendritic cell vaccination immunotherapy.

  2006cites this paper
• Expression of Transforming Growth Factor ßi by Human Endometrial Carcinoma Cell Lines: Inverse Correlation with Effects on Growth Rate and Morphology1

  2006cites this paper
• Immunotherapy of Central Nervous System Tumors

  2005cites this paper