An elevated amniotic fluid matrix metalloproteinase-8 level at the time of mid-trimester genetic amniocentesis is a risk factor for spontaneous preterm delivery.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  American Journal of Obstetrics and Gynecology

• Publication date

  2001-11-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1067/MOB.2001.117678PMID 11717651
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Preterm Prediction Study: association of second-trimester genitourinary chlamydia infection with subsequent spontaneous preterm birth.

  2000cited by this paper
• The Expression of MMP-8 in Human Odontoblasts and Dental Pulp Cells is Down-regulated by TGF-β1

  2000cited by this paper
• Clinical implications of detection of Ureaplasma urealyticum in the amniotic cavity with the polymerase chain reaction.

  2000cited by this paper
• Human neutrophil collagenase (matrix metalloproteinase 8) in parturition, premature rupture of the membranes, and intrauterine infection.

  2000cited by this paper
• The matrix metalloproteinase inhibitor BB‐1101 prevents experimental autoimmune uveoretinitis (EAU)

  1999cited by this paper
• Regulation of angiogenin expression in human HepG2 hepatoma cells by mediators of the acute-phase response.

  1999cited by this paper
• Matrix Metalloproteinase Inhibition: From The Jurassic To The Third Millennium

  1999cited by this paper
• Is amniotic fluid analysis the key to preterm labor? A model using interleukin-6 for predicting rapid delivery.

  1998cited by this paper
• Elevated second-trimester amniotic fluid interleukin-6 levels predict preterm delivery.

  1998cited by this paper
• Angiogenin: a marker for preterm delivery in midtrimester amniotic fluid.

  1997cited by this paper
• The use of the polymerase chain reaction to detect bacteria in amniotic fluid in pregnancies complicated by preterm labor.

  1997cited by this paper
• Matrix Metalloproteinase-8 Is Expressed in Rheumatoid Synovial Fibroblasts and Endothelial Cells

  1997cited by this paper
• Broad-spectrum bacterial rDNA polymerase chain reaction assay for detecting amniotic fluid infection among women in premature labor.

  1997cited by this paper
• Chondrocyte Matrix Metalloproteinase-8

  1996cited by this paper
• Elevated amniotic fluid interleukin-6 levels at genetic amniocentesis predict subsequent pregnancy loss.

  1996cited by this paper
• Suppression of experimental allergic encephalomyelitis in the Lewis rat by the matrix metalloproteinase inhibitor Ro31-9790

  1995cited by this paper
• Amniotic fluid interleukin-6: a sensitive test for antenatal diagnosis of acute inflammatory lesions of preterm placenta and prediction of perinatal morbidity.

  1995cited by this paper
• Association between bacterial vaginosis and preterm delivery of a low-birth-weight infant. The Vaginal Infections and Prematurity Study Group.

  1995cited by this paper
• Association between Bacterial Vaginosis and Preterm Delivery of a Low-Birth-Weight Infant

  1995cited by this paper
• A comparative study of the diagnostic performance of amniotic fluid glucose, white blood cell count, interleukin-6, and gram stain in the detection of microbial invasion in patients with preterm premature rupture of membranes.

  1993cited by this paper
• Release of proteinases from stimulated polymorphonuclear leukocytes. Evidence for subclasses of the main granule types and their association with cytoskeletal components.

  1991cited by this paper
• Preterm labor associated with subclinical amniotic fluid infection and with bacterial vaginosis.

  1986cited by this paper
• The fetal biophysical profile in patients with premature rupture of the membranes--an early predictor of fetal infection.

  1985cited by this paper
• The use of amniocentesis in patients with premature rupture of membranes.

  1979cited by this paper
• Beyond Normality: The Predictive Value and E ciency of Medical Diagnoses

  1975cited by this paper

• Functional MRI assessment of the lungs in fetuses that deliver very Preterm: An MRI pilot study

  2023cites this paper
• Maternal Infection and Preterm Birth: From Molecular Basis to Clinical Implications

  2023cites this paper
• Clinical chorioamnionitis at term: definition, pathogenesis, microbiology, diagnosis, and treatment.

  2023cites this paper
• A role for intraamniotic inflammation in threatened midtrimester miscarriage.

  2022cites this paper
• Preterm labor with intact membranes: a simple noninvasive method to identify patients at risk for intra-amniotic infection and/or inflammation

  2022cites this paper
• Adverse pregnancy and birth outcomes associated with Mycoplasma hominis, Ureaplasma urealyticum and Ureaplasma parvum: a systematic review and meta-analysis

  2022cites this paper
• Zinc homeostasis in immunity and its association with preterm births

  2022cites this paper
• Expression of antimicrobial peptides in the amniotic fluid of women with cervical insufficiency

  2022cites this paper
• The Relationship Among Intra-Amniotic Inflammatory Response, The Progression of Inflammation in Chorionic Plate and Early-Onset Neonatal Sepsis

  2021cites this paper
• The diagnosis and management of preterm labor with intact membranes

  2021cites this paper
• Second trimester fetal thymus size in association to preterm birth

  2021cites this paper
• The nature of the immune response in microbial-associated and sterile intraamniotic inflammation

  2021cites this paper
• The Interaction Between Microorganisms, Metabolites, and Immune System in the Female Genital Tract Microenvironment

  2020cites this paper
• A new rapid bedside test to diagnose and monitor intra-amniotic inflammation in preterm PROM using transcervically collected fluid.

  2020cites this paper
• Matrix Metalloproteinases Expressed in Response to Bacterial Vaginosis Disrupt the Endocervical Epithelium, Increasing Transmigration of HIV

  2020cites this paper
• Amniotic fluid cell-free transcriptome: a glimpse into fetal development and placental cellular dynamics during normal pregnancy

  2020cites this paper
• Mid-trimester amniotic fluid proteome’s association with spontaneous preterm delivery and gestational duration

  2020cites this paper
• Nucleic Acid-Based Screening of Maternal Serum to Detect Viruses in Women with Labor or PROM

  2020cites this paper
• Simple Periodontal Treatment Predict Preterm Surrogate Marker Levels

  2020cites this paper
• Biomarkers in mid-trimester amniotic fluid in relation to gestational duration and spontaneous preterm delivery

  2020cites this paper
• The significance of amniotic fluid immunological analysis for the prediction of intrauterine infection

  2020cites this paper
• Maternal blood endotoxin activity in pregnancies complicated by preterm premature rupture of membranes

  2019cites this paper
• The diagnostic performance of the beta-glucan assay in the detection of intra-amniotic infection with Candida species

  2019cites this paper
• Research Progress of Angiogenin in Reproduction

  2019cites this paper
• The association between selected mid-trimester amniotic fluid candidate proteins and spontaneous preterm delivery

  2018cites this paper
• The immunophenotype of amniotic fluid leukocytes in normal and complicated pregnancies

  2018cites this paper
• Comparison of rapid MMP-8 and interleukin-6 point-of-care tests to identify intra-amniotic inflammation/infection and impending preterm delivery in patients with preterm labor and intact membranes*

  2018cites this paper
• The Potential of Angiogenin as a Serum Biomarker for Diseases: Systematic Review and Meta-Analysis

  2018cites this paper
• Inflammation amniotique : son association avec la maladie parodontale et son impact sur le devenir neurologique de l'enfant

  2018influential citation
• Cervical Length and Matrix Metalloproteinase-8 Level in Endocervix of Spontaneous Preterm Labor

  2018cites this paper
• Clinical chorioamnionitis at term VIII: a rapid MMP-8 test for the identification of intra-amniotic inflammation.

  2017cites this paper
• Intrauterine Infection, Preterm Parturition, and the Fetal Inflammatory Response Syndrome

  2017cites this paper
• High Level of Uterine Endocervical Interleukin-8, Matrix Metalloproteinase-8, and Interleukin 1Β as a Risk Factor for Preterm Labor

  2017cites this paper
• 14 – Fetal and Maternal Responses to Intraamniotic Infection

  2017cites this paper
• Clinical chorioamnionitis at term VIII: a rapid MMP-8 test for the identification of intra-amniotic inflammation

  2017cites this paper
• Early- or mid-trimester amniocentesis biomarkers for predicting preterm delivery: a meta-analysis

  2017cites this paper
• Heterogeneity of the Intra-Amniotic Inflammatory Response during Pregnancy-FIRS Type I and II

  2017cites this paper
• A new anti-microbial combination prolongs the latency period, reduces acute histologic chorioamnionitis as well as funisitis, and improves neonatal outcomes in preterm PROM

  2016cites this paper
• Blood metal levels and third trimester maternal plasma matrix metalloproteinases (MMPs).

  2016cites this paper
• Differential amniotic fluid cytokine profile in women with chorioamnionitis with and without funisitis

  2016cites this paper
• Comparative Analysis of Midtrimester Amniotic Fluid Cytokine Levels to Predict Spontaneous Very Pre‐term Birth in Patients with Cervical Insufficiency

  2016cites this paper
• High MMP-9 and TNF-α expression increase in preterm premature rupture of membranes

  2016cites this paper
• Analysis of cervicovaginal fluid metabolome and microbiome in relation to preterm birth

  2016cites this paper
• Periodontal Disease and Adverse Pregnancy Outcomes: A Prospective Study in a Low-Risk Population.

  2016cites this paper
• Lactobacillus crispatus as biomarker of the healthy vaginal tract.

  2016cites this paper
• Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance.

  2015cites this paper
• Is There a Role for Probiotics in the Prevention of Preterm Birth?

  2015cites this paper
• The relationship between the intensity of intra-amniotic inflammation and the presence and severity of acute histologic chorioamnionitis in preterm gestation

  2015cites this paper
• Use of amniotic fluid for determining pregnancies at risk of preterm birth and for studying diseases of potential environmental etiology.

  2015cites this paper
• Mid-trimester amniotic fluid pro-inflammatory biomarkers predict the risk of spontaneous preterm delivery in twins: a retrospective cohort study

  2015cites this paper
• Clinical chorioamnionitis at term IV: the maternal plasma cytokine profile

  2015cites this paper
• Presenting Twins Are Exposed to Higher Levels of Inflammatory Mediators than Nonpresenting Twins as Early as the Midtrimester of Pregnancy

  2015cites this paper
• The Role of Probiotic Lactobacillus in Immune Regulation and Modulation of the Vaginal Microbiota During Pregnancy

  2015cites this paper
• Amniotic Fluid and the Fetal Mucosal Immune System

  2015cites this paper
• Wybrane metaloproteinazy i ich inhibitory w przewidywaniu skuteczności tokolizy nifedypiną

  2015cites this paper
• The vaginal microbiome, vaginal anti‐microbial defence mechanisms and the clinical challenge of reducing infection‐related preterm birth

  2015cites this paper
• About one-half of early spontaneous preterm deliveries can be identified by a rapid matrix metalloproteinase-8 (MMP-8) bedside test at the time of mid-trimester genetic amniocentesis*

  2015cites this paper
• Evidence of perturbations of the cytokine network in preterm labor.

  2015cites this paper
• A proposed bio-panel to predict risk for spontaneous preterm birth among African American women.

  2015cites this paper
• Influence of Vaginal Bacteria and d- and l-Lactic Acid Isomers on Vaginal Extracellular Matrix Metalloproteinase Inducer: Implications for Protection against Upper Genital Tract Infections

  2014cites this paper
• Amniotic fluid infection, inflammation, and colonization in preterm labor with intact membranes.

  2014cites this paper
• The diagnostic performance of the Mass Restricted (MR) score in the identification of microbial invasion of the amniotic cavity or intra-amniotic inflammation is not superior to amniotic fluid interleukin-6

  2014cites this paper
• Is thrombin activation predictive of subsequent preterm delivery?

  2013cites this paper
• The role and challenges of biomarkers in spontaneous preterm birth and preeclampsia.

  2013cites this paper
• Identification of biomarkers for preterm delivery in mid-trimester amniotic fluid.

  2013cites this paper
• Influence of Vaginal Bacteria and d- and l-Lactic Acid Isomers on Vaginal Extracellular Matrix Metalloproteinase Inducer: Implications for Protection against Upper Genital Tract Infections

  2013cites this paper
• The frequency and clinical significance of intra-amniotic inflammation defined as an elevated amniotic fluid matrix metalloproteinase-8 in patients with preterm labor and low amniotic fluid white blood cell counts

  2013cites this paper
• Effects of amniotic and maternal CD-146, TGF-β1, IL-12, IL-18 and Inf-γ, on adverse pregnancy outcome

  2013cites this paper
• Infection and smoking are associated with decreased plasma concentration of the anti-aging protein, α-klothoa

  2013cites this paper
• Infection and antibiotics in the aetiology, prediction and prevention of preterm birth

  2013cites this paper
• Correlation of midtrimester amniotic fluid cytokine concentrations with adverse pregnancy outcome in terms of spontaneous abortion, preterm birth, and preeclampsia

  2012cites this paper
• Proteomic analysis of midtrimester amniotic fluid to identify novel biomarkers for preterm delivery

  2012cites this paper
• Review: Impact of mediators present in amniotic fluid on preterm labour.

  2012cites this paper
• The frequency and clinical significance of intra-amniotic inflammation in women with preterm uterine contractility but without cervical change: do the diagnostic criteria for preterm labor need to be changed?

  2012cites this paper
• Altered expressions of MMP-2, MMP-9, and TIMP-2 in placentas from women exposed to lead

  2012cites this paper
• The clinical significance of a positive Amnisure test in women with preterm labor and intact membranes

  2012cites this paper
• Amniotic fluid inflammatory score is associated with pregnancy outcome in patients with mid trimester short cervix.

  2012cites this paper
• Risk of Preterm Delivery in Non-Diabetic Women with Polycystic Ovarian Syndrome

  2012cites this paper
• Intrauterine infection and preterm labor.

  2012cites this paper
• [The role of infection in preterm birth].

  2012cites this paper
• Midtrimester amniotic fluid concentrations of interleukin-6 and interferon-gamma-inducible protein-10: evidence for heterogeneity of intra-amniotic inflammation and associations with spontaneous early (<32 weeks) and late (>32 weeks) preterm delivery

  2012cites this paper
• N-acetylcysteine attenuates the maternal and fetal proinflammatory response to intrauterine LPS injection in an animal model for preterm birth and brain injury

  2011cites this paper
• Biomarkers of Spontaneous Preterm Birth: An Overview of The Literature in the Last Four Decades

  2011cites this paper
• Inflammatory cytokines and antioxidants in midtrimester amniotic fluid: correlation with pregnancy outcome.

  2011cites this paper
• Mid-trimester amniotic fluid concentrations of the proinflammatory cytokines IL-6, IL-8, TNF-α, and lipopolysaccharide binding protein in normal pregnancies: a prospective evaluation according to parity, gestational age, and fetal gender

  2011cites this paper
• Immune Aspects and Myometrial Actions of Progesterone and CRH in Labor

  2011cites this paper
• Seminars in Fetal & Neonatal Medicine

  2011cites this paper
• Anti-inflammatory mediators as physiological and pharmacological regulators of parturition

  2011cites this paper
• Novel biomarkers for the prediction of the spontaneous preterm birth phenotype: a systematic review and meta‐analysis

  2011cites this paper
• Hematologic profile of the fetus with systemic inflammatory response syndrome

  2011cites this paper
• Pre-Clinical and Clinical Pharmacology of 17alpha-Hydroxyprogesterone caproate (17-OHPC): An Agent for the Prevention of Preterm Birth.

  2010cites this paper
• Prevalence and Diversity of Microbes in the Amniotic Fluid, the Fetal Inflammatory Response, and Pregnancy Outcome in Women with Preterm Pre‐Labor Rupture of Membranes

  2010cites this paper
• The role of human beta defensins 2 and 3 in the second trimester amniotic fluid in predicting preterm labor and premature rupture of membranes

  2010cites this paper
• Chorioamnionitis--a complex pathophysiologic syndrome.

  2010cites this paper
• Amniotic fluid interleukin-6 and tumor necrosis factor-alpha at mid-trimester genetic amniocentesis: relationship to intra-amniotic microbial invasion and preterm delivery.

  2010cites this paper
• Patients with an asymptomatic short cervix (<or=15 mm) have a high rate of subclinical intraamniotic inflammation: implications for patient counseling.

  2010cites this paper
• The Matrix Metalloproteases and Endothelin-1 in Infection-Associated Preterm Birth

  2010cites this paper
• The clinical use of inflammatory markers during pregnancy

  2010cites this paper
• Inflammatory Cytokines and Spontaneous Preterm Birth in Asymptomatic Women: A Systematic Review

  2010cites this paper
• Rupture prématurée des membranes à terme et avant terme

  2010cites this paper