Generation of a transgenic rabbit model of retinal degeneration.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Investigative Ophthalmology and Visual Science

• Publication date

  2009-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1167/iovs.08-2863PMID 19074802
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mutation in CEP290 discovered for cat model of human retinal degeneration.

  2007cited by this paper
• Perspective on genes and mutations causing retinitis pigmentosa.

  2007cited by this paper
• Retinitis pigmentosa.

  2006cited by this paper
• Long-term stimulation by active epiretinal implants in normal and RCD1 dogs

  2005cited by this paper
• Encapsulated cell-based intraocular delivery of ciliary neurotrophic factor in normal rabbit: dose-dependent effects on ERG and retinal histology.

  2004cited by this paper
• Establishment of an efficient BAC transgenesis protocol and its application to functional characterization of the mouse Brachyury locus.

  2004cited by this paper
• Comparison of the clinical expression of retinitis pigmentosa associated with rhodopsin mutations at codon 347 and codon 23.

  2003cited by this paper
• Animal models in research on retinal degenerations: past progress and future hope.

  2002cited by this paper
• Activation of mislocalized opsin kills rod cells: A novel mechanism for rod cell death in retinal disease

  2002cited by this paper
• Naturally occurring rhodopsin mutation in the dog causes retinal dysfunction and degeneration mimicking human dominant retinitis pigmentosa

  2002cited by this paper
• The Diversity of Ganglion Cells in a Mammalian Retina

  2002cited by this paper
• Encapsulated cell-based delivery of CNTF reduces photoreceptor degeneration in animal models of retinitis pigmentosa.

  2002cited by this paper
• The relationship between opsin overexpression and photoreceptor degeneration.

  2001cited by this paper
• Size Matters: Use of YACs, BACs and PACs in Transgenic Animals

  2001cited by this paper
• Gene therapy restores vision in a canine model of childhood blindness

  2001cited by this paper
• Point mutation of bacterial artificial chromosomes by ET recombination

  2000cited by this paper
• A new logic for DNA engineering using recombination in Escherichia coli

  1998cited by this paper
• Animal models of human retinal dystrophies

  1998cited by this paper
• Rhodopsin mutations in inherited retinal dystrophies and dysfunctions

  1997cited by this paper
• Genetically engineered large animal model for studying cone photoreceptor survival and degeneration in retinitis pigmentosa

  1997cited by this paper
• Homologous recombination based modification in Esherichia coli and germline transmission in transgenic mice of a bacterial artificial chromsome

  1997cited by this paper
• Transgenic mice carrying the dominant rhodopsin mutation P347S: evidence for defective vectorial transport of rhodopsin to the outer segments.

  1996cited by this paper
• Topographical regulation of cone and rod opsin genes: parallel, position dependent levels of transcription.

  1995cited by this paper
• Fetal topography of bovine rhodopsin mRNA suggests retinotopographically determined gene expression.

  1995cited by this paper
• Mechanisms of rhodopsin inactivation in vivo as revealed by a COOH-terminal truncation mutant

  1995cited by this paper
• Regional topography of rod and immunocytochemically characterized “blue” and “green” cone photoreceptors in rabbit retina

  1995cited by this paper
• Basic science and inherited retinal disease

  1994cited by this paper
• Rod phototransduction in retinitis pigmentosa: estimation and interpretation of parameters derived from the rod a-wave.

  1994cited by this paper
• Transgenic mice with a rhodopsin mutation (Pro23His): a mouse model of autosomal dominant retinitis pigmentosa.

  1992cited by this paper
• Mutation spectrum of the rhodopsin gene among patients with autosomal dominant retinitis pigmentosa.

  1991cited by this paper
• The rod circuit in the rabbit retina

  1991cited by this paper
• Ocular findings in patients with autosomal dominant retinitis pigmentosa and rhodopsin, proline-347-leucine.

  1991cited by this paper
• Non-allelism of three genes (rcd1, rcd2 and erd) for early-onset hereditary retinal degeneration.

  1989cited by this paper
• Ganglion cell density in albino and pigmented rabbit retinas labeled with a ganglion cell-specific monoclonal antibody.

  1987cited by this paper
• Neurochemical stratification in the inner plexiform layer of the vertebrate retina.

  1986cited by this paper
• Specific binding of peanut lectin to a class of retinal photoreceptor cells. A species comparison.

  1984cited by this paper
• Hereditary progressive retinal atrophy in the Abyssinian cat

  1983cited by this paper
• Hereditary progressive retinal atrophy in the Abyssinian cat.

  1983cited by this paper
• Standard karyotype of the laboratory rabbit, Oryctolagus cuniculus

  1981cited by this paper
• Standard karyotype of the laboratory rabbit, Oryctolagus cuniculus.

  1981cited by this paper

• Calpain-1 C2L domain peptide protects retinal photoreceptor cells in rhodopsin P347L transgenic rabbits.

  2026cites this paper
• Rabbit Model of Oxidative Stress-Induced Retinal Degeneration.

  2025cites this paper
• Physiology and pathophysiology of the retinal neuroglia.

  2025cites this paper
• Bioactive Glial-Derived Neurotrophic Factor from a Safe Injectable Collagen–Alginate Composite Gel Rescues Retinal Photoreceptors from Retinal Degeneration in Rabbits

  2024cites this paper
• Neural Circuit Revision in Retinal Remodeling, A Pathoconnectomics Approach

  2024cites this paper
• Contribution of intraflagellar transport to compartmentalization and maintenance of the photoreceptor cell

  2024cites this paper
• Advances in the engineering of the outer blood-retina barrier: From in-vitro modelling to cellular therapy

  2023cites this paper
• Extracellular vesicles highlight many cases of photoreceptor degeneration

  2023cites this paper
• Retinal Pathoconnectomics: A Window into Neurodegeneration.

  2023cites this paper
• Current perspective on retinal remodeling: Implications for therapeutics

  2022cites this paper
• USH2A Gene Mutations in Rabbits Lead to Progressive Retinal Degeneration and Hearing Loss

  2022cites this paper
• Microvesicle release from inner segments of healthy photoreceptors is a conserved phenomenon in mammalian species

  2022cites this paper
• Кролі як біологічна модель для експериментальних досліджень (огляд літератури)

  2021cites this paper
• Outer Retinal Cell Replacement: Putting the Pieces Together

  2021cites this paper
• Large-Area Photoreceptor Degeneration Model in Rabbits by Photocoagulation and Oxidative Stress in the Retina

  2021cites this paper
• Gene Editing in Rabbits: Unique Opportunities for Translational Biomedical Research

  2021cites this paper
• A rat model for retinitis pigmentosa with rapid retinal degeneration enables drug evaluation in vivo

  2021cites this paper
• Rabbits as a biological model for experimental studies (review of literature)

  2021cites this paper
• A Pathoconnectome of Early Neurodegeneration

  2020cites this paper
• RPE Cells Engulf Microvesicles Secreted by Degenerating Rod Photoreceptors

  2020cites this paper
• Spectral Domain Optical Coherence Tomography in Awake Rabbits Allows Identification of the Visual Streak, a Comparison with Histology

  2020cites this paper
• Persistent remodeling and neurodegeneration in late-stage retinal degeneration.

  2020cites this paper
• Transgenic Rabbit Models: Now and the Future

  2020cites this paper
• Establishment and Characterization of a Unilateral UV-Induced Photoreceptor Degeneration Model in the C57Bl/6J Mouse

  2020cites this paper
• A pathoconnectome of early neurodegeneration: Network changes in retinal degeneration.

  2020cites this paper
• The Absence of Calponin 2 in Rabbits Suggests Caution in Choosing Animal Models

  2020cites this paper
• Ophthalmic Imaging Interspecies Variation of Outer Retina and Choriocapillaris Imaged With Optical Coherence Tomography

  2019cites this paper
• Pathoconnectome Analysis of Müller Cells in Early Retinal Remodeling.

  2019cites this paper
• The effects of intravitreal sodium iodate injection on retinal degeneration following vitrectomy in rabbits

  2019cites this paper
• Interspecies Variation of Outer Retina and Choriocapillaris Imaged With Optical Coherence Tomography.

  2019cites this paper
• OFF-layer Branches of ON Cone Bipolar Cells in Early Retinal Degeneration

  2019cites this paper
• ТРАНСГЕННЫЕ И НОКАУТНЫЕ КРОЛИКИ В БИОМЕДИЦИНЕ И ГЕНОТЕРАПИИ. CRISPR/CAS9-ТЕХНОЛОГИИ (ОБЗОР)

  2019cites this paper
• PRCD is essential for high-fidelity photoreceptor disc formation

  2019cites this paper
• Course of loss of photoreceptor function and progressive Müller cell gliosis in rhodopsin P347L transgenic rabbits.

  2019cites this paper
• Interspecies variation of outer retina and choriocapillaris imaged with optical coherence tomography (OCT)

  2019cites this paper
• Electrically Evoked Potentials Are Reduced Compared to Axon Numbers in Rhodopsin P347L Transgenic Rabbits With Severe Photoreceptor Degeneration.

  2019cites this paper
• Phenotypic characterization of P23H and S334ter rhodopsin transgenic rat models of inherited retinal degeneration

  2018cites this paper
• Generation of an acute retinal photoreceptor degeneration model in rabbits.

  2018cites this paper
• Visual evoked potential in rabbits’ eyes with subretinal implantation by vitrectomy of Okayama University-type retinal prosthesis (OURePTM)

  2018cites this paper
• The molecular and cellular basis of rhodopsin retinitis pigmentosa reveals potential strategies for therapy.

  2017cites this paper
• Retina Contributions of Second-and Third-Order Retinal Neurons to Cone Electroretinograms After Loss of Rod Function in Rhodopsin P 347 L Transgenic Rabbits

  2017cites this paper
• Principles and Applications of Rabbit Models for Atherosclerosis Research

  2017cites this paper
• Contributions of Second- and Third-Order Retinal Neurons to Cone Electroretinograms After Loss of Rod Function in Rhodopsin P347L Transgenic Rabbits.

  2017cites this paper
• Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models

  2017cites this paper
• Temporal Properties of Flicker ERGs in Rabbit Model of Retinitis Pigmentosa.

  2017cites this paper
• Histopathological Changes of Inner Retina, Optic Disc, and Optic Nerve in Rabbit with Advanced Retinitis Pigmentosa

  2016cites this paper
• Long-Term Protection of Genetically Ablated Rabbit Retinal Degeneration by Sustained Transscleral Unoprostone Delivery.

  2016cites this paper
• Conserved and divergent expression patterns of markers of axial development in eutherian mammals

  2016influential citation
• Protective effects of sustained transscleral unoprostone delivery against retinal degeneration in S334ter rhodopsin mutant rats.

  2016cites this paper
• Müller cell metabolic chaos during retinal degeneration.

  2016influential citation
• Monocular retinal degeneration induced by intravitreal injection of sodium iodate in rabbit eyes

  2016cites this paper
• Efficient Generation of Myostatin Gene Mutated Rabbit by CRISPR/Cas9

  2016cites this paper
• Rabbit Models of Ocular Diseases: New Relevance for Classical Approaches.

  2016cites this paper
• Neuoroprotective efficacies by KUS121, a VCP modulator, on animal models of retinal degeneration

  2016cites this paper
• CRISPR/Cas9-mediated GJA8 knockout in rabbits recapitulates human congenital cataracts

  2016cites this paper
• Cytoprotective Effects of a Novel Nrf2 Activator, RS9, in Rhodopsin Pro347Leu Rabbits

  2016cites this paper
• Retinal histopathology in eyes from patients with autosomal dominant retinitis pigmentosa caused by rhodopsin mutations

  2015cites this paper
• Rabbit models for the study of human atherosclerosis: from pathophysiological mechanisms to translational medicine.

  2015cites this paper
• Functional and morphological study of retinal photoreceptor cell degeneration in transgenic rabbits with a Pro347Leu rhodopsin mutation

  2015cites this paper
• Advancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano Symposium.

  2015cites this paper
• Chapter 3 - Restoring Vision to the Blind: Gene Therapy for Vision Loss.

  2014cites this paper
• Inner and outer retinal changes in retinal degenerations associated with ABCA4 mutations.

  2014cites this paper
• Chapter 2 - Restoring Vision to the Blind: Optogenetics.

  2014cites this paper
• Germline transgenesis in rabbits by pronuclear microinjection of Sleeping Beauty transposons

  2014cites this paper
• Generation of knockout rabbits using transcription activator-like effector nucleases

  2014cites this paper
• Restoring Vision to the Blind : Optogenetics The Lasker / IRRF Initiative for Innovation in Vision Science Discussion Leaders :

  2014cites this paper
• Production of Transgenic Rabbits

  2014cites this paper
• Designer Zinc Finger Nuclease: A Versatile Tool for Genome Editing in Animals

  2014cites this paper
• Germline transgenesis in rodents by pronuclear microinjection of Sleeping Beauty transposons

  2014cites this paper
• Restoring Vision to the Blind: Optogenetics

  2014cites this paper
• Restoring Vision to the Blind: Gene Therapy for Vision Loss: The Road Ahead

  2014cites this paper
• Kingfisher Biotech Circular Subject : Rabbit as an Animal Model

  2013cites this paper
• Transgenic Zebrafish Models for Understanding Retinitis Pigmentosa

  2013cites this paper
• The retina-prosthesis interface in two rat models of retinitis pigmentosa and functional changes associated with photoreceptor loss.

  2013cites this paper
• Genetically modified animals as potential genetic resources.

  2013cites this paper
• Retinal remodeling

  2012cites this paper
• Cell replacement and visual restoration by retinal sheet transplants.

  2012cites this paper
• The Use of Domestic Animals as Biomedical Models Generation of rabbit pluripotent stem cell lines

  2012cites this paper
• Rabbit Genetics and Transgenic Models

  2012cites this paper
• Review Generation of rabbit pluripotent stem cell lines

  2012cites this paper
• Genetically modified species in research: opportunities and challenges for the histology core laboratory

  2012cites this paper
• Photoreceptor and post-photoreceptoral contributions to photopic ERG a-wave in rhodopsin P347L transgenic rabbits.

  2012cites this paper
• Transcorneal electrical stimulation promotes survival of photoreceptors and improves retinal function in rhodopsin P347L transgenic rabbits.

  2012cites this paper
• Generation of rabbit pluripotent stem cell lines.

  2012cites this paper
• Real-Time Imaging of Rabbit Retina with Retinal Degeneration by Using Spectral-Domain Optical Coherence Tomography

  2012influential citation
• On the emerging role of rabbit as human disease model and the instrumental role of novel transgenic tools

  2012cites this paper
• Efficient Immunoglobulin Gene Disruption and Targeted Replacement in Rabbit Using Zinc Finger Nucleases

  2011cites this paper
• Retinal remodeling in the Tg P347L rabbit, a large‐eye model of retinal degeneration

  2011influential citation
• The Applications of Transgenic Rabbits in Agriculture and Biomedicine

  2011cites this paper
• Enhancement of ON-bipolar cell responses of cone electroretinograms in rabbits with the Pro347Leu rhodopsin mutation.

  2011cites this paper
• Focal cone ERGs of rhodopsin Pro347Leu transgenic rabbits.

  2010cites this paper
• Mutations of the Opsin Gene (Y102H and I307N) Lead to Light-induced Degeneration of Photoreceptors and Constitutive Activation of Phototransduction in Mice*

  2010cites this paper
• Pharmacological dissection of multifocal electroretinograms of rabbits with Pro347Leu rhodopsin mutation

  2010cites this paper
• Harmonic analysis of the cone flicker ERG of rabbit.

  2010cites this paper
• Molecular Endocrinology

  2009cites this paper
• Induced pluripotent stem cells for retinal degenerative diseases: a new perspective on the challenges

  2009cites this paper
• Supernormal ERG oscillatory potentials in transgenic rabbit with rhodopsin P347L mutation and retinal degeneration.

  2009cites this paper
• Electrical excitation of degenerate retina

  2009cites this paper
• Transgenic mouse technology: principles and methods.

  2009cites this paper
• Investigation of Animal Models and Surgical Techniques for Development of Retinal Prosthesis

  2008cites this paper