Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2006-03-24

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.BBRC.2006.01.072PMID 16460677
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pluripotency of mesenchymal stem cells derived from adult marrow

  2007cited by this paper
• Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion.

  2005cited by this paper
• Functional studies of mesenchymal stem cells derived from adult human adipose tissue.

  2005cited by this paper
• Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation

  2004cited by this paper
• Extrapancreatic insulin-producing cells in multiple organs in diabetes.

  2004cited by this paper
• In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow.

  2004influential reference
• No evidence for significant transdifferentiation of bone marrow into pancreatic beta-cells in vivo.

  2004cited by this paper
• Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation.

  2004cited by this paper
• Adult Bone Marrow Stromal Cells in the Embryonic Brain: Engraftment, Migration, Differentiation, and Long-Term Survival

  2004cited by this paper
• Characterization and Expression Analysis of Mesenchymal Stem Cells from Human Bone Marrow and Adipose Tissue

  2004cited by this paper
• Islet Regeneration During the Reversal of Autoimmune Diabetes in NOD Mice

  2003cited by this paper
• Neuroectodermal differentiation from mouse multipotent adult progenitor cells

  2003cited by this paper
• Heterogeneity among human bone marrow-derived mesenchymal stem cells and neural progenitor cells.

  2003cited by this paper
• Comparison of Multi-Lineage Cells from Human Adipose Tissue and Bone Marrow

  2003cited by this paper
• In vitro and in vivo calcitonin I gene expression in parenchymal cells: a novel product of human adipose tissue.

  2003cited by this paper
• In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion.

  2003cited by this paper
• Membrane properties of rat embryonic multipotent neural stem cells

  2003cited by this paper
• Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain.

  2002cited by this paper
• Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells.

  2002cited by this paper
• Pluripotency of mesenchymal stem cells derived from adult marrow

  2002cited by this paper
• Gastrin stimulates beta-cell neogenesis and increases islet mass from transdifferentiated but not from normal exocrine pancreas tissue.

  2002cited by this paper
• In vitro trans-differentiation of adult hepatic stem cells into pancreatic endocrine hormone-producing cells

  2002cited by this paper
• Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter.

  2002cited by this paper
• Human adipose tissue is a source of multipotent stem cells.

  2002cited by this paper
• Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes.

  2001cited by this paper
• The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

  2001cited by this paper
• Adult rat and human bone marrow stromal cells differentiate into neurons

  2000cited by this paper
• Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow.

  2000cited by this paper
• Multilineage potential of adult human mesenchymal stem cells.

  1999cited by this paper
• Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats--similarities to astrocyte grafts.

  1998cited by this paper
• Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

  1997influential reference
• Betacellulin and activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells.

  1996cited by this paper
• Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice.

  1995cited by this paper
• CNS stem cells express a new class of intermediate filament protein.

  1990cited by this paper
• STROMAL CELLS RESPONSIBLE FOR TRANSFERRING THE MICROENVIRONMENT OF THE HEMOPOIETIC TISSUES: Cloning In Vitro and Retransplantation In Vivo

  1974cited by this paper

• Solitary rectal ulcer: mechanisms of development, diagnosis and modern approaches to treatment (review)

  2026cites this paper
• Alpha Lipoic Acid Promotes the Proliferation, Motility, and Antioxidant Defense System of Human Adipose‐Derived Stromal/Stem Cells

  2026cites this paper
• Physical differentiation of adipose-derived mesenchymal stem cells into pancreatic beta-like cells using cell-imprinting and evaluation of insulin production

  2026cites this paper
• The Promise of Cell-Based Therapies in Diabetes: A Review of Mesenchymal Stem Cell Applications and Trials.

  2025cites this paper
• Pancreatic islet organoids and organoids on-chip for type 1 diabetes.

  2025cites this paper
• The Potential and Challenges of Human Pluripotent Stem Cells in the Treatment of Diabetic Nephropathy.

  2025cites this paper
• Preclinical research in obesity-associated metabolic diseases using in vitro, multicellular, and non-mammalian models

  2025cites this paper
• Acquisition of durable insulin-producing cells from human adipose tissue-derived mesenchymal stem cells as a foundation for cell- based therapy of diabetes mellitus

  2024cites this paper
• Current status of stem cell therapy for type 1 diabetes: a critique and a prospective consideration

  2024cites this paper
• Advanced therapy to cure diabetes: mission impossible is now possible?

  2024cites this paper
• Progress and application of adipose-derived stem cells in the treatment of diabetes and its complications

  2024cites this paper
• Human mesenchymal stem/stromal cell based-therapy in diabetes mellitus: experimental and clinical perspectives

  2024cites this paper
• DNA Methyltransferase Inhibition by RG108 Improves Stemness and Multipotential Differentiation of Human Adipose Tissue-derived Stem Cells

  2024cites this paper
• Gene Therapy Based on Mesenchymal Stem Cells Derived from Adipose Tissue for the Treatment of Obesity and Its Metabolic Complications

  2023cites this paper
• Exosomes from adipose-derived stem cells inhibits skin cancer progression via miR-199a-5p/SOX4

  2023cites this paper
• Transplantation of adipose derived stem cells in diabetes mellitus; limitations and achievements

  2023cites this paper
• Adipose-derived Mesenchymal Stem Cells Therapy as a new Treatment Option for Diabetes Mellitus

  2023cites this paper
• Using adipose‐derived mesenchymal stem cells to fight the metabolic complications of obesity: Where do we stand?

  2022cites this paper
• Deducing Insulin-Producing Cells from Goat Adipose Tissue-Derived Mesenchymal Stem Cells

  2022cites this paper
• Mesenchymal Stem Cell Therapeutic Potential in Regenerative Medicine and Its Future Direction

  2022cites this paper
• Recent Progress of Research Regarding the Applications of Stem Cells for Treating Diabetes Mellitus

  2022cites this paper
• Current progress and emerging technologies for generating extrapancreatic functional insulin-producing cells

  2022cites this paper
• Conversion of Gastrointestinal Somatostatin-Expressing D Cells Into Insulin-Producing Beta-Like Cells Upon Pax4 Misexpression

  2022cites this paper
• Transplantation of insulin-producing cells derived from human mesenchymal stromal/stem cells into diabetic humanized mice

  2022cites this paper
• A One-Step, Monolayer Culture and Chemical-Based Approach to Generate Insulin-Producing Cells From Human Adipose-Derived Stem Cells to Mitigate Hyperglycemia in STZ-Induced Diabetic Rats

  2022cites this paper
• Therapeutic efficacy of adipose-derived mesenchymal stem cells after chronic fluoxetine treatment on pars distalis in adult male albino rats.

  2022cites this paper
• Tailored generation of insulin producing cells from canine mesenchymal stem cells derived from bone marrow and adipose tissue

  2021cites this paper
• Navigating the Genomic Landscape of Human Adipose Stem Cell-Derived β-Cells

  2021cites this paper
• Stem Cell-Based Clinical Trials for Diabetes Mellitus

  2021cites this paper
• Differentiation of Adipose-Derived Stem Cells into Vascular Smooth Muscle Cells for Tissue Engineering Applications

  2021cites this paper
• More to Explore; The Mesenchymal Stem Cells (MSCs) Major Tissue Sources, Known Surface Markers, and Its Immunomodulation properties

  2021cites this paper
• Adipose tissue-derived stem cells: a comparative review on isolation, culture, and differentiation methods

  2021cites this paper
• Intrapancreatic MSC transplantation facilitates pancreatic islet regeneration

  2021cites this paper
• Treatment of diabetic mice by microfluidic system-assisted transplantation of stem cells-derived insulin-producing cells transduced with miRNA.

  2021cites this paper
• Adipose derived stem cells to construct parathyroid organoid for hypoparathyroidism.

  2021cites this paper
• Stem Cells as a Source of Pancreatic Cells for Production of 3D Bioprinted Bionic Pancreas in the Treatment of Type 1 Diabetes

  2021cites this paper
• Chitosan for biomedical applications, promising antidiabetic drug delivery system, and new diabetes mellitus treatment based on stem cell.

  2021cites this paper
• Characterization and therapeutic applications of mesenchymal stem cells for regenerative medicine.

  2020cites this paper
• Recent Advance in Source, Property, Differentiation, and Applications of Infrapatellar Fat Pad Adipose-Derived Stem Cells

  2020cites this paper
• Human Adipose Tissue Derivatives as a Potent Native Biomaterial for Tissue Regenerative Therapies

  2020cites this paper
• Insulin-producing cells from mesenchymal stromal cells: Protection against cognitive impairment in diabetic rats depends upon implant site.

  2020cites this paper
• Class I and II Histone Deacetylase Inhibitor LBH589 Promotes Endocrine Differentiation in Bone Marrow Derived Human Mesenchymal Stem Cells and Suppresses Uncontrolled Proliferation.

  2020cites this paper
• Functional beta-cells derived from umbilical cord blood mesenchymal stem cells for curing rats with streptozotocin-induced diabetes mellitus.

  2020cites this paper
• Cellular therapies in preclinical and clinical islet transplantation: Mesenchymal stem cells

  2020cites this paper
• Isolation, culture, and induced multiple differentiation of Mongolian sheep adipose-derived mesenchymal stem cells

  2020cites this paper
• Differentiation of canine adipose mesenchymal stem cells into insulin-producing cells: comparison of different culture medium compositions.

  2020cites this paper
• Microencapsulation of cellular aggregate composed of differentiated insulin and glucagon-producing cells from human mesenchymal stem cells derived from adipose tissue. CURRENT STATUS: UNDER REVIEW

  2020cites this paper
• Tailor-made generation of insulin-producing cells from canine mesenchymal stem cells derived from bone marrow and adipose tissue

  2020cites this paper
• Human Mesenchymal Stem Cells: The Present Alternative for High-Incidence Diseases, Even SARS-Cov-2

  2020cites this paper
• Nanoengineering of stem cells for neural regenerative medicine

  2020cites this paper
• Effects mediated by the α7 nicotinic acetylcholine receptor on cell proliferation and migration in rat adipose-derived stem cells

  2020cites this paper
• Introduction and Basic Concepts in Stem Cell Research and Therapy: The Facts and the Hype

  2020cites this paper
• Application of Mesenchymal Stem Cells in Inflammatory and Fibrotic Diseases

  2020cites this paper
• IN VITRO DIFFERENTIATION OF WHARTON’S JELLY-DERIVED MESENCHYMAL STEM CELLS INTO ENDOCRINE PANCREATIC LINEAGE

  2020cites this paper
• From Mesenchymal Stromal/Stem Cells to Insulin-Producing Cells: Progress and Challenges

  2020cites this paper
• Random Differentiation of Bone Marrow Derived Mesenchymal Stem Cells

  2020cites this paper
• Comparison of insulin secretion by transduced adipose-derived and endometrial-derived stem cells in 2D and 3D cultures on fibrin scaffold.

  2020cites this paper
• STEMCELL: An Instrument to Improve Outcomes of Islet Transplantation

  2020cites this paper
• Landscape of transcription and expression regulated by DNA methylation related to age of donor and cell passage in adipose-derived mesenchymal stem cells

  2020cites this paper
• Hypoxia Pretreatment Promotes Chondrocyte Differentiation of Human Adipose-Derived Stem Cells via Vascular Endothelial Growth Factor

  2020cites this paper
• Mesenchymal stem cells promote pancreatic β-cell regeneration through downregulation of FoxO1 pathway

  2020cites this paper
• Microencapsulation of cellular aggregates composed of differentiated insulin and glucagon-producing cells from human mesenchymal stem cells derived from adipose tissue

  2020cites this paper
• Distinct roles for Notch1 and Notch3 in human adipose-derived stem/stromal cell adipogenesis

  2020cites this paper
• Differentiation of Human Deceased Donor, Adipose-Derived, Mesenchymal Stem Cells into Functional Beta Cells.

  2020cites this paper
• Regenerative and Transplantation Medicine: Cellular Therapy Using Adipose Tissue-Derived Mesenchymal Stromal Cells for Type 1 Diabetes Mellitus

  2019influential citation
• Comparison of different cryopreservation protocols for human umbilical cord tissue as source of mesenchymal stem cells.

  2019cites this paper
• Biocompatibility of mesenchymal stromal cells of adipose tissue with osteoplastic materials (in vitro)

  2019cites this paper
• An overview on small molecule-induced differentiation of mesenchymal stem cells into beta cells for diabetic therapy

  2019cites this paper
• Application of Tonsil‐Derived Mesenchymal Stem Cells in Tissue Regeneration: Concise Review

  2019cites this paper
• Differentiation Potential of Nestin (+) and Nestin (-) Cells Derived from Human Bone Marrow Mesenchymal Stem Cells into Functional Insulin Producing Cells.

  2019cites this paper
• Stem cells and their physiological effects

  2019cites this paper
• Applications of stem cells and bioprinting for potential treatment of diabetes

  2019cites this paper
• The Development of Facial Lipofilling from a Historical Point of View

  2019cites this paper
• Fall 2014 3 D differentiation enhances the efficiency of differentiation of human induced pluripotent stem cells to insulin producing cells

  2019cites this paper
• Concise Review: Application of tonsil-derived mesenchymal stem cells in tissue regeneration.

  2019cites this paper
• Adipose-derived stem cells: Sources, potency, and implications for regenerative therapies.

  2019cites this paper
• Short-Term Protocols to Obtain Insulin-Producing Cells from Rat Adipose Tissue: Signaling Pathways and In Vivo Effect

  2019cites this paper
• In vitro and in vivo effects of insulin-producing cells generated by xeno-antigen free 3D culture with RCP piece

  2019cites this paper
• A simple method for the generation of insulin producing cells from bone marrow mesenchymal stem cells

  2019cites this paper
• Long-Term Biobanking of Intact Tissue from Lipoaspirate

  2019cites this paper
• Effect of human adipose-derived regenerative cells on temporomandibular joint healing in immunodeficient rabbits

  2019cites this paper
• In vitro differentiation of single donor derived human dental mesenchymal stem cells into pancreatic β cell-like cells

  2019cites this paper
• Collagen I Promotes Adipocytogenesis in Adipose-Derived Stem Cells In Vitro

  2019cites this paper
• The role of stem cells in anti-aging medicine.

  2019cites this paper
• Role of adipose tissue derived stem cells differentiated into insulin producing cells in the treatment of type I diabetes mellitus.

  2018cites this paper
• Insight into the development of obesity: functional alterations of adipose‐derived mesenchymal stem cells

  2018cites this paper
• Autologous fat grafting: Latest insights

  2018cites this paper
• COMPARATIVE STUDY OF HIV-POSITIVE HUMAN SERA WITH THIRD- AND FOURTH-GENERATION ENZYME IMMUNOASSAY TEST SYSTEMS

  2018cites this paper
• Epigenetic and Transcriptome Profiling Identifies a Population of Visceral Adipose-Derived Progenitor Cells with the Potential to Differentiate into an Endocrine Pancreatic Lineage

  2018cites this paper
• Directing adipose‐derived stem cells into keratinocyte‐like cells: impact of medium composition and culture condition

  2018cites this paper
• Studio dell'effetto immunomodulatorio in vitro di NGAL su PBMC di pazienti in trattamento emodialitico e iperimmuni

  2018cites this paper
• A review: therapeutic potential of adipose-derived stem cells in cutaneous wound healing and regeneration

  2018cites this paper
• Experience of stem cell use in treatment of skin burns

  2018cites this paper
• Hydrogels for Stem Cell Encapsulation: Toward Cellular Therapy for Diabetes

  2018cites this paper
• Differentiation of conjunctiva mesenchymal stem cells into secreting islet beta cells on plasma treated electrospun nanofibrous scaffold

  2018cites this paper
• Functional Hydrogels as Biomaterials

  2018cites this paper
• Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus.

  2018cites this paper
• Expansion of transplanted islets in mice by co-transplantation with adipose tissue-derived mesenchymal stem cells

  2018influential citation
• Pancreatic endocrine‐like cells differentiated from human umbilical cords Wharton’s jelly mesenchymal stem cells using small molecules

  2018cites this paper
• MiR-374b promotes osteogenic differentiation of MSCs by degrading PTEN and promoting fracture healing.

  2018cites this paper