Regulatory divergence modifies limb length between mammals.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Genes & Development

• Publication date

  2008-01-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1101/gad.1620408PMID 18198333PMCID PMC2192750
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2019cited by this paper
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  2006cited by this paper
• Development of bat flight: morphologic and molecular evolution of bat wing digits.

  2006cited by this paper
• Repeated morphological evolution through cis-regulatory changes in a pleiotropic gene

  2006cited by this paper
• A Molecular Phylogeny for Bats Illuminates Biogeography and the Fossil Record

  2005cited by this paper
• Comparative functional genomics revealed conservation and diversification of three enhancers of the isl1 gene for motor and sensory neuron-specific expression.

  2005cited by this paper
• Embryonic staging system for the short‐tailed fruit bat, Carollia perspicillata, a model organism for the mammalian order Chiroptera, based upon timed pregnancies in captive‐bred animals

  2005cited by this paper
• Evolution at Two Levels: On Genes and Form

  2005cited by this paper
• Chance caught on the wing: cis-regulatory evolution and the origin of pigment patterns in Drosophila

  2005cited by this paper
• Dual regulation and redundant function of two eye-specific enhancers of the Drosophila retinal determination gene dachshund

  2005cited by this paper
• Single base pair change in the long‐range Sonic hedgehog limb‐specific enhancer is a genetic basis for preaxial polydactyly

  2005cited by this paper
• Distinguishing the contributions of the perichondrium, cartilage, and vascular endothelium to skeletal development.

  2004cited by this paper
• Mammalian phylogenomics comes of age.

  2004cited by this paper
• Evolution of regulatory elements producing a conserved gene expression pattern in Caenorhabditis

  2004cited by this paper
• Genetic and developmental basis of evolutionary pelvic reduction in threespine sticklebacks

  2004cited by this paper
• The use of composite taxa in supermatrices.

  2004cited by this paper
• Molecular ontogeny of the skeleton.

  2003cited by this paper
• Transcriptional regulation and the evolution of development.

  2003cited by this paper
• Drosophila pigmentation evolution: Divergent genotypes underlying convergent phenotypes

  2003cited by this paper
• Regulatory evolution of shavenbaby/ovo underlies multiple cases of morphological parallelism

  2003cited by this paper
• Review of: Carroll, Sean B., Jennifer K. Grenier and Scott D. Weatherbee: From DNA to diversity : molecular genetics and the evolution of animal design. Malden, Mass [u.a.]: Blackwell Science 2001

  2003cited by this paper
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  2002cited by this paper
• Redundant and Unique Roles of Two Enhancer Elements in the TCRγ Locus in Gene Regulation and γδ T Cell Development

  2002cited by this paper
• FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease.

  2002cited by this paper
• Manipulating the Mouse Embryo: A Laboratory Manual

  2002influential reference
• Investigation of Prx1 protein expression provides evidence for conservation of cardiac‐specific posttranscriptional regulation in vertebrates

  2001cited by this paper
• Comparative studies on limb morphogenesis in mice and bats: a functional genetic approach towards a molecular understanding of diversity in organ formation.

  2001cited by this paper
• The evolution of flight and echolocation in bats: another leap in the dark

  2001cited by this paper
• Autoregulation and multiple enhancers control Math1 expression in the developing nervous system.

  2000cited by this paper
• PERSPECTIVE: EVOLUTIONARY DEVELOPMENTAL BIOLOGY AND THE PROBLEM OF VARIATION

  2000cited by this paper
• Identification of a prx1 limb enhancer

  2000cited by this paper
• Divergence of larval morphology between Drosophila sechellia and its sibling species caused by cis-regulatory evolution of ovo/shaven-baby.

  2000cited by this paper
• From DNA to Diversity: Molecular Genetics and the Evolution of Animal Design

  2000cited by this paper
• Role of the Intronic Elements in the Endogenous Immunoglobulin Heavy Chain Locus

  1999cited by this paper
• In situ hybridization: a practical approach

  1998cited by this paper
• A role of Ultrabithorax in morphological differences between Drosophila species

  1998cited by this paper
• Phylogenetic relationships of Icaronycteris, Archaeonycteris, Hassianycteris, and Palaeochiropteryx to extant bat lineages, with comments on the evolution of echolocation and foraging strategies in Microchiroptera. Bulletin of the AMNH ; no. 235

  1998cited by this paper
• Prx1 and Prx2 in skeletogenesis: roles in the craniofacial region, inner ear and limbs.

  1998cited by this paper
• Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells.

  1997cited by this paper
• Improved procedures for maintaining and breeding the short-tailed fruit bat (Carollia perspicillata) in a laboratory setting

  1996cited by this paper
• Long-range disruption of gene expression by a selectable marker cassette.

  1996cited by this paper
• The paired-like homeo box gene MHox is required for early events of skeletogenesis in multiple lineages.

  1995influential reference
• Müllerian-inhibiting substance function during mammalian sexual development.

  1994cited by this paper
• Genomic DNA microextraction: a method to screen numerous samples.

  1992cited by this paper
• MHox: a mesodermally restricted homeodomain protein that binds an essential site in the muscle creatine kinase enhancer.

  1992cited by this paper
• Inducible expression of an hsp68-lacZ hybrid gene in transgenic mice.

  1989cited by this paper
• Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

  1988cited by this paper
• Enhancers: mechanisms of action and cell specificity.

  1988cited by this paper
• Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs.

  1985cited by this paper
• The Origin of Species by means of Natural Selection; or the Preservation of Favoured Races in the Struggle for Life

  1872cited by this paper

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  2026cites this paper
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  2026cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2024cites this paper
• DNA-guided transcription factor cooperativity shapes face and limb mesenchyme.

  2024cites this paper
• A Scaffolding Element Rewires Local 3D Chromatin Architecture During Differentiation

  2024cites this paper
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  2024cites this paper
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  2024cites this paper
• The case against simplistic genetic explanations of evolution

  2024cites this paper
• Distinct gene regulatory dynamics drive skeletogenic cell fate convergence during vertebrate embryogenesis

  2024cites this paper
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  2023cites this paper
• Insights into the formation and diversification of a novel chiropteran wing membrane from embryonic development

  2023cites this paper
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  2023cites this paper
• Chromatin accessibility associated with aquaculture relevant traits in tilapia

  2023cites this paper
• Phenotypic innovation in one tooth induced concerted developmental evolution in another

  2023influential citation
• Resolving the mechanisms underlying epithelial‐to‐mesenchymal transition of the lateral plate mesoderm

  2023cites this paper
• [Epigenetics, principles and examples of applications].

  2023cites this paper
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  2023cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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