Trophic actions of GABA on neuronal development.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Trends in Neurosciences

• Publication date

  2005-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.TINS.2005.03.010PMID 15927682
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Two developmental switches in GABAergic signalling: the K+–Cl− cotransporter KCC2 and carbonic anhydrase CAVII

  2005cited by this paper
• Interneurons set the tune of developing networks.

  2004influential reference
• Quantitative effects produced by modifications of neuronal activity on the size of GABAA receptor clusters in hippocampal slice cultures

  2004cited by this paper
• Local structural balance and functional interaction of excitatory and inhibitory synapses in hippocampal dendrites

  2004cited by this paper
• Do pediatric drugs cause developing neurons to commit suicide?

  2004cited by this paper
• Homeostatic plasticity in the developing nervous system

  2004cited by this paper
• Spontaneous synaptic activity is required for the formation of functional GABAergic synapses in the developing rat hippocampus

  2004cited by this paper
• Hyperpolarizing Inhibition Develops without Trophic support by GABA in Cultured Rat Midbrain Neurons

  2003cited by this paper
• BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl- co-transporter KCC2

  2003cited by this paper
• Developmental up‐regulation of KCC2 in the absence of GABAergic and glutamatergic transmission

  2003cited by this paper
• Impaired dendritic spine maturation in GABAA receptor α1 subunit knock out mice

  2003cited by this paper
• In vitro formation of a secondary epileptogenic mirror focus by interhippocampal propagation of seizures

  2003cited by this paper
• Autocrine/Paracrine Activation of the GABAA Receptor Inhibits the Proliferation of Neurogenic Polysialylated Neural Cell Adhesion Molecule-Positive (PSA-NCAM+) Precursor Cells from Postnatal Striatum

  2003cited by this paper
• GABA‐induced neurite outgrowth of cerebellar granule cells is mediated by GABAA receptor activation, calcium influx and CaMKII and erk1/2 pathways

  2003cited by this paper
• WWW.ScienceDirect.com

  2003cited by this paper
• Activity-dependent remodeling of presynaptic inputs by postsynaptic expression of activated CaMKII.

  2003cited by this paper
• Blockade of GABA(B) receptors alters the tangential migration of cortical neurons.

  2003cited by this paper
• Impaired dendritic spine maturation in GABAA receptor alpha1 subunit knock out mice.

  2003cited by this paper
• Borodinsky, L. N. et al. GABA-induced neurite outgrowth of cerebellar granule cells is mediated by GABAA receptor activation, calcium influx and CaMKII and erk1/2 pathways. J. Neurochem. 84, 1411-1420

  2003cited by this paper
• Excitatory actions of GABA increase BDNF expression via a MAPK-CREB-dependent mechanism--a positive feedback circuit in developing neurons.

  2002cited by this paper
• Is there more to gaba than synaptic inhibition?

  2002cited by this paper
• Paracrine intercellular communication by a Ca2+- and SNARE-independent release of GABA and glutamate prior to synapse formation.

  2002cited by this paper
• GAT-1 and reversible GABA transport in Bergmann glia in slices.

  2002cited by this paper
• Modes of neuronal migration in the developing cerebral cortex

  2002cited by this paper
• TrkB receptor signaling is required for establishment of GABAergic synapses in the cerebellum

  2002cited by this paper
• In vivo blockade of neural activity alters dendritic development of neonatal CA1 pyramidal cells

  2002cited by this paper
• Postsynaptic action of BDNF on GABAergic synaptic transmission in the superficial layers of the mouse superior colliculus.

  2002cited by this paper
• On the Origin of Interictal Activity in Human Temporal Lobe Epilepsy in Vitro

  2002cited by this paper
• Antiepileptic drugs and apoptotic neurodegeneration in the developing brain

  2002cited by this paper
• Early expression of glycine and GABA(A) receptors in developing spinal cord neurons. Effects on neurite outgrowth.

  2001cited by this paper
• Glial transporters for glutamate, glycine, and GABA III. Glycine transporters

  2001cited by this paper
• BDNF reduces miniature inhibitory postsynaptic currents by rapid downregulation of GABAA receptor surface expression

  2001cited by this paper
• GABA Expression Dominates Neuronal Lineage Progression in the Embryonic Rat Neocortex and Facilitates Neurite Outgrowth via GABAA Autoreceptor/Cl− Channels

  2001cited by this paper
• GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition.

  2001cited by this paper
• NMDA receptor activation limits the number of synaptic connections during hippocampal development

  2001cited by this paper
• Environmental factors and disturbances of brain development.

  2001cited by this paper
• Glial transporters for glutamate, glycine, and GABA: II. GABA transporters

  2001cited by this paper
• Neurotransmitters as early signals for central nervous system development

  2001cited by this paper
• GABA promotes survival but not proliferation of parvalbumin-immunoreactive interneurons in rodent neostriatum: an in vivo study with stereology.

  2001cited by this paper
• Brain-derived neurotrophic factor modulates dendritic morphology of cerebellar basket and stellate cells: an in vitro study.

  2000cited by this paper
• GABA release from mouse axonal growth cones

  2000cited by this paper
• TrkB Receptor Ligands Promote Activity-Dependent Inhibitory Synaptogenesis

  2000cited by this paper
• Postsynaptic target specificity of neurotrophin-induced presynaptic potentiation.

  2000cited by this paper
• Neuronal Activity and Brain-Derived Neurotrophic Factor Regulate the Density of Inhibitory Synapses in Organotypic Slice Cultures of Postnatal Hippocampus

  2000influential reference
• Differential Modulation of Proliferation in the Neocortical Ventricular and Subventricular Zones

  2000cited by this paper
• Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome.

  2000cited by this paper
• Synaptic assembly of the brain in the absence of neurotransmitter secretion.

  2000cited by this paper
• BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex.

  1999cited by this paper
• GABA induces proliferation of immature cerebellar granule cells grown in vitro.

  1999cited by this paper
• The Establishment of GABAergic and Glutamatergic Synapses on CA1 Pyramidal Neurons is Sequential and Correlates with the Development of the Apical Dendrite

  1999cited by this paper
• GABA and histogenesis in fetal and neonatal mouse brain lacking both the isoforms of glutamic acid decarboxylase.

  1999cited by this paper
• The K+/Cl− co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation

  1999cited by this paper
• Congenital malformations due to antiepileptic drugs.

  1999cited by this paper
• GABA Inhibits Migration of Luteinizing Hormone-Releasing Hormone Neurons in Embryonic Olfactory Explants

  1998cited by this paper
• Muscimol-induced death of GABAergic neurons in rat brain aggregating cell cultures.

  1998cited by this paper
• Differential Response of Cortical Plate and Ventricular Zone Cells to GABA as a Migration Stimulus

  1998cited by this paper
• Orchestration of neuronal migration by activity of ion channels, neurotransmitter receptors, and intracellular Ca2+ fluctuations.

  1998cited by this paper
• GABA as a trophic factor for developing monoamine neurons.

  1998cited by this paper
• Neurotrophins Induce Formation of Functional Excitatory and Inhibitory Synapses between Cultured Hippocampal Neurons

  1998cited by this paper
• Oscillations Mediated by the Synergistic Excitatory Actions of GABAA and NMDA Receptors in the Neonatal Hippocampus

  1997cited by this paper
• Immunoreactivity for GABA plasma membrane transporter, GAT-1, in the developing rat cerebral cortex: transient presence in the somata of neocortical and hippocampal neurons.

  1997cited by this paper
• Activation of the GABAA Receptor Inhibits the Proliferative Effects of bFGF in Cortical Progenitor Cells

  1997cited by this paper
• GABAergic stimulation regulates the phenotype of hippocampal interneurons through the regulation of brain-derived neurotrophic factor.

  1996cited by this paper
• GABA and glutamate depolarize cortical progenitor cells and inhibit DNA synthesis.

  1995cited by this paper
• GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro.

  1995cited by this paper
• The NeurotroDhins BDNF, NT‐3 and NT‐4/5 Promote Survival and Morphological and Biochemical Differentiation of Striatal Neurons In Vitro

  1995cited by this paper
• Intraventricular administration of BDNF increases neuropeptide expression in newborn rat brain

  1994cited by this paper
• Involvement of GABAA receptors in the outgrowth of cultured hippocampal neurons.

  1993cited by this paper
• Prenatal exposure to ethanol alters the postnatal development and transformation of radial glia to astrocytes in the cortex

  1993cited by this paper
• Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons.

  1991cited by this paper
• Neurotrophic effects of GABA in cultures of embryonic chick brain and retina

  1988cited by this paper
• Uptake and release of [3H]GABA by growth cones isolated from neonatal rat brain.

  1984cited by this paper
• Development/Plasticity/Repair Brain-Derived Neurotrophic Factor Mediates Activity- Dependent Dendritic Growth in Nonpyramidal Neocortical Interneurons in Developing Organotypic Cultures

  year unknowncited by this paper

• Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

  2026cites this paper
• Endoplasmic reticulum protein retention and disturbed proteostasis is a common pathology for a subset of autism: evidence from mutations in GABAA receptors and GABA transporter 1

  2026cites this paper
• Cortical parvalbumin-positive neurons: Functional and ontogenetic characteristics and their relationship to brain pathologies.

  2026cites this paper
• Segment Regeneration of an Earthworm I: Formation of the Body Wall Tissues from Injury to Recovery

  2026cites this paper
• GABA induces myokine irisin release from skeletal muscle.

  2026cites this paper
• KCC2 phosphorylation dynamics relate to oligomerization during development and after spinal cord injury.

  2026cites this paper
• GABAergic integration of transient and persistent neurons in the developing mouse somatosensory cortex

  2025cites this paper
• Multi-behavioral fingerprints can identify potential modes of action for neuroactive environmental chemicals.

  2025cites this paper
• Bringing Chandelier Cells Out of the Shadows: Exploring the Development of a Unique Neuron Type in the Brain.

  2025cites this paper
• Altered Auditory Maturation in Fragile X Syndrome and Its Involvement in Audiogenic Seizure Susceptibility

  2025cites this paper
• Identification of Neuroactive Chemicals in Crude Oil-Derived Water-Accommodated Fractions

  2025cites this paper
• Neurosteroid replacement therapy using tiagabine and zuranolone restores cerebellar neurodevelopment and reduces hyperactive behaviour following preterm birth

  2025cites this paper
• Abnormal neurodevelopment predisposes to cortical hyperexcitability in Huntington's disease.

  2025cites this paper
• The Functional Interplay among GAD2, GABRG2, and CACNA1G Genes in Cancers

  2025cites this paper
• GABAB receptors regulate the neural stem cell potential of Pkd2l1+ cerebrospinal fluid-contacting neurons via the PI3K/Akt signaling pathway.

  2025cites this paper
• Investigation of Peroxisome Proliferator-Activated Receptor Genes as Requirements for Visual Startle Response Hyperactivity in Larval Zebrafish Exposed to Structurally Similar Per- and Polyfluoroalkyl Substances (PFAS)

  2024cites this paper
• GABAB receptor‐mediated modulation in the developing dorsal nucleus of the lateral lemniscus

  2024cites this paper
• Corticostriatal maldevelopment in the R6/2 mouse model of juvenile Huntington's disease.

  2024cites this paper
• Basal Forebrain Cholinergic Neurons Have Specific Characteristics during the Perinatal Period

  2024cites this paper
• The domestic chick as an animal model of autism spectrum disorder: building adaptive social perceptions through prenatally formed predispositions

  2024cites this paper
• Decreased GABA levels during development result in increased connectivity in the larval zebrafish tectum

  2024cites this paper
• Behavioral and Sensory Deficits Associated with Dysfunction of GABAergic System in a Novel shank2-Deficient Zebrafish Model

  2023cites this paper
• Instructions for use

  2023cites this paper
• Exposure to chlorpyrifos during pregnancy differentially affects social behavior and GABA signaling elements in an APOE- and sex-dependent manner in a transgenic mouse model.

  2023cites this paper
• Understanding the Role of ATP Release through Connexins Hemichannels during Neurulation

  2023cites this paper
• Understanding the genetic mechanisms and cognitive impairments in Down syndrome: towards a holistic approach

  2023cites this paper
• The role of individual neuronutrients in optimizing nutritional therapy for neurological patients

  2023cites this paper
• A role for the serotonin 2A receptor in the expansion and functioning of human transmodal cortex.

  2023cites this paper
• Tonic activation of GABAB receptors via GAT-3 mediated GABA release reduces network activity in the developing somatosensory cortex in GAD67-GFP mice

  2023cites this paper
• Atlas of Fetal Metabolism During Mid-To-Late Gestation and Diabetic Pregnancy

  2023cites this paper
• Effects of Pregnanolone Glutamate and Its Metabolites on GABAA and NMDA Receptors and Zebrafish Behavior

  2023cites this paper
• Emerging Anti-Diabetic Drugs for Beta-Cell Protection in Type 1 Diabetes

  2023cites this paper
• Developmental localization of potassium chloride co-transporter 2 (KCC2) in the Purkinje cells of embryonic mouse

  2023cites this paper
• Secondhand smoke’s effects on brain development: ADHD and associated behaviors in children

  2023cites this paper
• Modulation of transcription factors by small molecules in β-cell development and differentiation.

  2023cites this paper
• Keeping the Balance: GABAB Receptors in the Developing Brain and Beyond

  2022cites this paper
• Intra-uterine diazepam exposure decreases the number of catecholaminergic and serotoninergic neurons of neonate rats.

  2022cites this paper
• Chronic, episodic nicotine exposure alters GABAergic transmission to hypoglossal motor neurons and genioglossus muscle function at a critical developmental age.

  2022cites this paper
• Function and development of interneurons involved in brain tissue oxygen regulation

  2022cites this paper
• Effect of early embryonic exposure to morphine on defects in the GABAergic system of day-old chicks.

  2022cites this paper
• De Novo Missense Variants in SLC32A1 Cause a Developmental and Epileptic Encephalopathy Due to Impaired GABAergic Neurotransmission

  2022cites this paper
• Lutein levels in arterial cord blood correlate with neurotrophic calcium binding S100B protein in healthy preterm and term newborns

  2022cites this paper
• Early life GABAA blockade alters the synaptic plasticity and cognitive functions in male and female rats.

  2022cites this paper
• Remodeling of lateral geniculate nucleus projections to extrastriate area MT following long-term lesions of striate cortex

  2022cites this paper
• GABAergic signaling beyond synapses: an emerging target for cancer therapy.

  2022cites this paper
• Fetal imidacloprid causes ASD-like impairment of biological motion perception in neonatal chicks

  2022cites this paper
• Fetal blockade of nicotinic acetylcholine transmission causes autism-like impairment of biological motion preference in the neonatal chick

  2022cites this paper
• Lack of placental neurosteroid alters cortical development and female somatosensory function

  2022cites this paper
• Postnatal GABAA Receptor Activation Alters Synaptic Plasticity and Cognition in Adult Wistar Rats

  2022cites this paper
• Time Window of the Critical Period for Neuroplasticity in S1, V1, and A1 Sensory Areas of Small Rodents: A Systematic Review

  2022cites this paper
• Specific Expression of KCC2 in the α Cells of Normal and Type 1 Diabetes Model Mouse Pancreatic Islets

  2022cites this paper
• Gabrb3 endothelial cell-specific knockout mice display abnormal blood flow, hypertension, and behavioral dysfunction

  2022cites this paper
• Gain-of-function and loss-of-function GABRB3 variants lead to distinct clinical phenotypes in patients with developmental and epileptic encephalopathies

  2022cites this paper
• Hyperexcitability and Homeostasis in Fragile X Syndrome

  2022cites this paper
• Loss of KCC2 in GABAergic Neurons Causes Seizures and an Imbalance of Cortical Interneurons

  2022cites this paper
• Channelopathies in fragile X syndrome

  2021cites this paper
• Cognitive Dysfunction in the Offspring of Rats with Experimental Preeclampsia at the Early and Late Stages of Ontogeny and Its Correction with GABA Derivatives

  2021cites this paper
• Cognitive Dysfunction in the Offspring of Rats with Experimental Preeclampsia at the Early and Late Stages of Ontogeny and Its Correction with GABA Derivatives

  2021cites this paper
• Neonatal NMDA blockade alters the LTP, LTD and cognitive functions in male and female Wistar rats.

  2021cites this paper
• De novo missense variants in SLC32A1 cause a neurodevelopmental disorder with epilepsy due to impaired GABAergic neurotransmission

  2021cites this paper
• Mechanisms for establishment of GABA signaling in adrenal medullary chromaffin cells

  2021cites this paper
• Repeated endosulfan exposure induces changes in neurochemicals, decreases ATPase transmembrane ionic-pumps, and increased oxidative/nitrosative stress in the brains of rats: Reversal by quercetin.

  2021cites this paper
• Preterm Birth Alters the Maturation of the GABAergic System in the Human Prefrontal Cortex

  2021cites this paper
• Therapeutically leveraging GABAA receptors in cancer

  2021cites this paper
• A synthetic peptide rescues rat cortical neurons from anesthetic-induced cell death, perturbation of growth and synaptic assembly

  2021cites this paper
• Development of the GABAergic network in the mouse spinal cord

  2021cites this paper
• GAD67-mediated GABA Synthesis and Signaling Impinges on Directing Basket Cell Axonal Projections Toward Purkinje Cells in the Cerebellum

  2021cites this paper
• Dysregulation of Neuronal Nicotinic Acetylcholine Receptor–Cholesterol Crosstalk in Autism Spectrum Disorder

  2021cites this paper
• Neuro-Signals from Gut Microbiota: Perspectives for Brain Glioma

  2021cites this paper
• GABA and glutamate in the preterm neonatal brain: In-vivo measurement by magnetic resonance spectroscopy

  2021cites this paper
• A potential role for somatostatin signaling in regulating retinal neurogenesis

  2021cites this paper
• Weak Association Between the Glutamate Decarboxylase 1 Gene (GAD1) and Schizophrenia in Han Chinese Population

  2021cites this paper
• Parallels between the Developing Vascular and Neural Systems: Signaling Pathways and Future Perspectives for Regenerative Medicine

  2021cites this paper
• An alternative splicing hypothesis for neuropathology of schizophrenia: evidence from studies on historical candidate genes and multi-omics data

  2021cites this paper
• Age and Sex Influences Gamma-aminobutyric Acid Concentrations in the Developing Brain of Very Premature Infants

  2020cites this paper
• Title: A novel synthetic peptide provides neuroprotection and rescues rat cortical neurons

  2020cites this paper
• Neurotransmitters as Modulators of Neural Progenitor Cell Proliferation During Mammalian Neocortex Development

  2020cites this paper
• The early overgrowth theory of autism spectrum disorder: Insight into convergent mechanisms from valproic acid exposure and translational models.

  2020cites this paper
• A synthetic peptide rescues rat cortical neurons from anesthetic-induced cell death and modulation of growth and synaptic assembly

  2020cites this paper
• Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) acutely affect human α1β2γ2L GABAA receptor and spontaneous neuronal network function in vitro

  2020cites this paper
• Gestational alcohol exposure disrupts cognitive function and striatal circuits in adult offspring

  2020cites this paper
• Paracrine Role for Somatostatin Interneurons in the Assembly of Perisomatic Inhibitory Synapses

  2020cites this paper
• Site-specific effects of neurosteroids on GABAA receptor activation and desensitization

  2020cites this paper
• Prenatal and Early Postnatal Cerebral d-Aspartate Depletion Influences l-Amino Acid Pathways, Bioenergetic processes, and Developmental Brain Metabolism.

  2020cites this paper
• Development and persistence of neuropathic pain through microglial activation and KCC2 decreasing after mouse tibial nerve injury.

  2020cites this paper
• Rats deficient in the GAD65 isoform exhibit epilepsy and premature lethality

  2020cites this paper
• Physiologic maturation is both extrinsically and intrinsically regulated in progenitor-derived neurons

  2020cites this paper
• Overlapping Molecular Pathways Leading to Autism Spectrum Disorders, Fragile X Syndrome, and Targeted Treatments

  2020cites this paper
• Roles of GABA signaling in directing basket cell axonal 1 projections toward Purkinje cells in the cerebellum 2 3 Running title : GAD 67 deficiency in the cerebellum 4 5

  2020cites this paper
• Combined the GABA-A and GABA-B receptor agonists attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism.

  2020cites this paper
• Modulations in the ATPases during ketamine-induced schizophrenia and regulatory effect of “3-(3, 4-dimethoxy phenyl) -1- (4-methoxyphenyl) prop-2-en-1-one”: an in vivo and in silico studies

  2020cites this paper
• Multimodal GABAA receptor functions in the development of the central nervous system

  2020cites this paper
• Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios

  2020cites this paper
• Quest for pharmacological regulators of KCC2

  2020cites this paper
• Environmental regulation of the chloride transporter KCC2: switching inflammation off to switch the GABA on?

  2020cites this paper
• Regulation of retinal neurogenesis by somatostatin signaling

  2020cites this paper
• Residual molecular and behavioral effects of the phenylpyrazole pesticide fipronil in larval zebrafish (Danio rerio) following a pulse embryonic exposure.

  2020cites this paper
• KCC2 regulates dendritic spine development

  2020cites this paper
• The Epilepsy-Related Protein PCDH19 Regulates Tonic Inhibition, GABAAR Kinetics, and the Intrinsic Excitability of Hippocampal Neurons

  2020cites this paper
• Gonadal hormone‐independent sex differences in GABAA receptor activation in rat embryonic hypothalamic neurons

  2020cites this paper