New insights into the function of Rab GTPases in the context of exosomal secretion

ABSTRACT In the last two decades, extracellular vesicle-mediated communication between cells has become a major field in cell biology. However, the function of extracellular vesicles is far from clear, especially due to the disparity of released vesicles by cells. Basically, one must consider vesicles budding from the cell plasma membrane (ectosomes) and vesicles released upon fusion of an endosomal multivesicular compartment (exosomes). Moreover, even for exosomes, we report and discuss here the possibility that different routes regulated by specific Rab GTPases might produce exosomes having various biologic functions.

• Publication year

  2017

• Venue

  Small GTPases

• Publication date

  2017-01-31

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1080/21541248.2016.1264352PMID 28135905PMCID 5902209
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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