Involvement of CD252 (CD134L) and IL-2 in the Expression of Cytotoxic Proteins in Bacterial- or Viral-Activated Human T Cells1

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Journal of Immunology

• Publication date

  2009-06-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.0800296PMID 19494280
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mycobacterium tuberculosis prevents inflammasome activation.

  2008cited by this paper
• Granzyme A cleaves a mitochondrial complex I protein to initiate caspase-independent cell death.

  2008cited by this paper
• Noncytotoxic Lytic Granule–Mediated CD8+ T Cell Inhibition of HSV-1 Reactivation from Neuronal Latency

  2008cited by this paper
• Effector and memory CTL differentiation.

  2007cited by this paper
• Acquisition of murine NK cell cytotoxicity requires the translation of a pre-existing pool of granzyme B and perforin mRNAs.

  2007cited by this paper
• Expression and function of the OX40/OX40L costimulatory pair during herpes stromal keratitis

  2007cited by this paper
• Expression, processing and transcriptional regulation of granulysin in short-term activated human lymphocytes

  2007cited by this paper
• Live Covisualization of Competing Adeno-Associated Virus and Herpes Simplex Virus Type 1 DNA Replication: Molecular Mechanisms of Interaction

  2007cited by this paper
• Human tumor-derived exosomes selectively impair lymphocyte responses to interleukin-2.

  2007cited by this paper
• Tuberculosis-associated haemophagocytic syndrome.

  2006cited by this paper
• A91V perforin variation in healthy subjects and FHLH patients

  2006cited by this paper
• Human Cytomegalovirus Attenuates Interleukin-1β and Tumor Necrosis Factor Alpha Proinflammatory Signaling by Inhibition of NF-κB Activation

  2006cited by this paper
• Phenotypical and Functional Analysis of Memory and Effector Human CD8 T Cells Specific for Mycobacterial Antigens1

  2006cited by this paper
• HHV-6 and the immune system: mechanisms of immunomodulation and viral escape.

  2006influential reference
• Effect of Antibody to CD134 on Perforin-Mediated Cytolysis in Human Peripheral Blood Mononuclear Cells

  2006influential reference
• Cholesterol in Negatively Charged Lipid Bilayers Modulates the Effect of the Antimicrobial Protein Granulysin

  2006cited by this paper
• Human cytomegalovirus attenuates interleukin-1beta and tumor necrosis factor alpha proinflammatory signaling by inhibition of NF-kappaB activation.

  2006cited by this paper
• Cell selectivity correlates with membrane-specific interactions: a case study on the antimicrobial peptide G15 derived from granulysin.

  2006cited by this paper
• Human dendritic cells process and present Listeria antigens for in vitro priming of autologous CD4+ T lymphocytes

  2005cited by this paper
• Uptake of Granulysin via Lipid Rafts Leads to Lysis of Intracellular Listeria innocua

  2005cited by this paper
• Perforin and lymphohistiocytic proliferative disorders

  2005cited by this paper
• Chlamydia pneumoniae induces aponecrosis in human aortic smooth muscle cells

  2005cited by this paper
• Protective Responses in Tuberculosis: Induction of Genes for Interferon‐γ and Cytotoxicity by Mycobacterium tuberculosis and During Human Tuberculosis

  2004cited by this paper
• Cytoplasmic Entry of Listeria monocytogenes Enhances Dendritic Cell Maturation and T Cell Differentiation and Function

  2004cited by this paper
• Lipoprotein processing is required for virulence of Mycobacterium tuberculosis †

  2004cited by this paper
• Disparate In Vitro and In Vivo Requirements for IL-2 During Antigen-Independent CD8 T Cell Expansion1

  2004cited by this paper
• Role of T cell costimulation in anti-viral immunity.

  2004influential reference
• Human NKT Cells Express Granulysin and Exhibit Antimycobacterial Activity 1

  2003influential reference
• Lymphocyte-mediated cytotoxicity.

  2003cited by this paper
• Cell death and immunity: The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal

  2003cited by this paper
• Cell‐mediated cytotoxicity in recovery from poxvirus infections

  2003cited by this paper
• The lymphotoxin beta receptor is critically involved in controlling infections with the intracellular pathogens Mycobacterium tuberculosis and Listeria monocytogenes.

  2003cited by this paper
• Mini‐review The role of interleukin‐12 in human infectious diseases: only a faint signature

  2003influential reference
• Costimulation of T cells by OX40, 4-1BB, and CD27.

  2003cited by this paper
• The Lymphotoxin β Receptor Is Critically Involved in Controlling Infections with the Intracellular Pathogens Mycobacterium tuberculosis and Listeria monocytogenes1

  2003cited by this paper
• The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses.

  2002cited by this paper
• The B7–CD28 superfamily

  2002cited by this paper
• Selective expansion of perforin‐positive CD8+ T cells by immature dendritic cells infected with live Bacillus Calmette‐Guérin mycobacteria

  2002cited by this paper
• The genes for perforin, granzymes A-C and IFN-gamma are differentially expressed in single CD8(+) T cells during primary activation.

  2002cited by this paper
• T-cell release of granulysin contributes to host defense in leprosy

  2001cited by this paper
• CD4+ and CD8+ T Cells Kill Intracellular Mycobacterium tuberculosis by a Perforin and Fas/Fas Ligand-Independent Mechanism1

  2001cited by this paper
• Gamma Interferon Can Prevent Herpes Simplex Virus Type 1 Reactivation from Latency in Sensory Neurons

  2001cited by this paper
• CD4 and CD8 T Cells Kill Intracellular Mycobacterium tuberculosis by a Perforin and Fas/Fas Ligand-Independent Mechanism

  2001influential reference
• Tuberculosis associated haemophagocytic syndrome.

  2001cited by this paper
• Role of CD8+ T cells in mycobacterial infections

  2000cited by this paper
• Impairment of Antigen-Presenting Cell Function in Mice Lacking Expression of Ox40 Ligand

  2000cited by this paper
• Perforin-mediated lysis of tumor cells by Mycobacterium bovis Bacillus Calmette-Guérin-activated killer cells.

  2000influential reference
• Granzyme A, a Noncytolytic Component of CD8+ Cell Granules, Restricts the Spread of Herpes Simplex Virus in the Peripheral Nervous Systems of Experimentally Infected Mice

  2000cited by this paper
• Clearance of Chlamydia trachomatis from the Murine Genital Mucosa Does Not Require Perforin-Mediated Cytolysis or Fas-Mediated Apoptosis

  1999cited by this paper
• Perforin Is Essential for Control of Ectromelia Virus but Not Related Poxviruses in Mice

  1999cited by this paper
• Listeria monocytogenes and recurrent mycobacterial infections in a child with complete interferon-gamma-receptor (IFNgammaR1) deficiency: mutational analysis and evaluation of therapeutic options.

  1999cited by this paper
• Cell-mediated immunity: dealing a direct blow to pathogens.

  1999cited by this paper
• Inflammatory cytokines provide a third signal for activation of naive CD4+ and CD8+ T cells.

  1999cited by this paper
• OX40-deficient mice are defective in Th cell proliferation but are competent in generating B cell and CTL Responses after virus infection.

  1999cited by this paper
• Role of innate and adaptive immunity in the outcome of primary infection with Chlamydia pneumoniae, as analyzed in genetically modified mice.

  1999cited by this paper
• IL-12 and IFN-gamma in host defense against mycobacteria and salmonella in mice and men.

  1999cited by this paper
• Perforin pathway is essential for protection of mice against lethal ocular HSV-1 challenge but not corneal scarring.

  1999cited by this paper
• Gamma Interferon Production by Cytotoxic T Lymphocytes Is Required for Resolution of Chlamydia trachomatis Infection

  1998cited by this paper
• An antimicrobial activity of cytolytic T cells mediated by granulysin.

  1998influential reference
• Ox-40 ligand: a potent costimulatory molecule for sustaining primary CD4 T cell responses.

  1998cited by this paper
• Novel human immunodeficiencies reveal the essential role of type-I cytokines in immunity to intracellular bacteria.

  1998cited by this paper
• The course of Mycobacterium tuberculosis infection in the lungs of mice lacking expression of either perforin- or granzyme-mediated cytolytic mechanisms

  1997cited by this paper
• Evidence for CD8+ T-cell immunity to murine rotavirus in the absence of perforin, fas, and gamma interferon

  1997cited by this paper
• Perforin, a cytotoxic molecule which mediates cell necrosis, is not required for the early control of mycobacterial infection in mice

  1997cited by this paper
• Immunological control of murine gammaherpesvirus infection is independent of perforin.

  1997cited by this paper
• Interleukin-1.

  1997cited by this paper
• IL-4 secretion by CD4+ NK1+ T cells induces monocyte chemoattractant protein-1 in early listeriosis.

  1997cited by this paper
• Cytokines and immunity to viral infections

  1997cited by this paper
• A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection.

  1996cited by this paper
• CD28/B7 system of T cell costimulation.

  1996cited by this paper
• Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia.

  1996cited by this paper
• New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

  1996cited by this paper
• Herpes simplex virus type 1-mediated up-regulation of IL-12 (p40) mRNA expression. Implications in immunopathogenesis and protection.

  1996cited by this paper
• Human dendritic cells phagocytose and process Borrelia burgdorferi.

  1996cited by this paper
• Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells.

  1995cited by this paper
• The roles of perforin‐ and Fas‐dependent cytotoxicity in protection against cytopathic and noncytopathic viruses

  1995influential reference
• Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors

  1995cited by this paper
• Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

  1994cited by this paper
• CD8+ T cell‐mediated protection against an intracellular bacterium by perforin‐dependent cytotoxicity

  1994cited by this paper
• Protective cytotoxic T lymphocytes are induced during murine infection with Chlamydia trachomatis.

  1994cited by this paper
• An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection

  1993cited by this paper
• Modulatory effects of Epstein-Barr, herpes simplex, and human herpes-6 viral infections and coinfections on cytokine synthesis. A comparative study.

  1992cited by this paper
• Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities.

  1991cited by this paper
• Functional heterogeneity among herpes simplex virus-specific human CD4+ T cells.

  1991cited by this paper
• A central role of perforin in cytolysis?

  1991cited by this paper
• Interleukin 2 induction of pore-forming protein gene expression in human peripheral blood CD8+ T cells

  1990cited by this paper
• IL-2 and IL-6 synergize to augment the pore-forming protein gene expression and cytotoxic potential of human peripheral blood T cells.

  1990cited by this paper
• Regulation of T‐Cell Activation; Differences among T‐Cell Subsets

  1989cited by this paper
• Lymphocyte-mediated cytotoxicity.

  1987cited by this paper
• Interleukin‐1

  1987cited by this paper
• Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules.

  1985cited by this paper

• Probiotics Surface-Delivering Fiber2 Protein of Fowl Adenovirus 4 Stimulate Protective Immunity Against Hepatitis-Hydropericardium Syndrome in Chickens

  2022cites this paper
• Oxidative and Non-Oxidative Antimicrobial Activities of the Granzymes

  2021cites this paper
• A fowl adenovirus serotype 4 (FAdV-4) Fiber2 subunit vaccine candidate provides complete protection against challenge with virulent FAdV-4 strain in chickens.

  2021cites this paper
• Effector function of CTLs is increased by irradiated colorectal tumor cells that modulate OX-40L and 4-1BBL and is reversed following dual blockade

  2016cites this paper
• Efectos inmunomoduladores de las dietas lipídicas y papel determinante en los estados de inmunosupresión

  2016cites this paper
• Analysis of a Genetic Polymorphism in the Costimulatory Molecule TNFSF4 with Hematopoietic Stem Cell Transplant Outcomes.

  2016cites this paper
• Radiation epigenetically modulates tumor cells and alters activation and function of effector T cells

  2015cites this paper
• Increased intra- and extracellular granzyme expression in patients with tuberculosis.

  2015cites this paper
• Alteration of UCP2 and ZO-1 Expression in Trabecular Meshwork of Neovascular Glaucoma Patients

  2015cites this paper
• Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes.

  2014cites this paper
• Divergence of immunologic and protective responses of different BCG strains in a murine model.

  2011cites this paper
• Association between BCG-induced immunity and risk of TB disease

  2011cites this paper