CD8+ T cell‐mediated protection against an intracellular bacterium by perforin‐dependent cytotoxicity

No abstract is available for this paper.

• Publication year

  1994

• Venue

  European Journal of Immunology

• Publication date

  1994-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/eji.1830241223PMID 7805735
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Neutrophils are essential for early anti-Listeria defense in the liver, but not in the spleen or peritoneal cavity, as revealed by a granulocyte-depleting monoclonal antibody

  1994cited by this paper
• Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity.

  1994cited by this paper
• Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

  1994cited by this paper
• Different roles of αβ and γδ T cells in immunity against an intracellular bacterial pathogen

  1993cited by this paper
• The role of cytokines in experimental listeriosis.

  1993cited by this paper
• Immune response in mice that lack the interferon-gamma receptor.

  1993cited by this paper
• Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection.

  1993cited by this paper
• Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

  1993cited by this paper
• Different roles of alpha beta and gamma delta T cells in immunity against an intracellular bacterial pathogen.

  1993cited by this paper
• Listeria monocytogenes infection in beta 2 microglobulin-deficient mice

  1993cited by this paper
• H-2M3 presents a Listeria monocytogenes peptide to cytotoxic T lymphocytes.

  1992cited by this paper
• Specialized role for a murine class I-b MHC molecule in prokaryotic host defenses.

  1992cited by this paper
• CD8 T cells can protect against an intracellular bacterium in an interferon gamma-independent fashion.

  1992cited by this paper
• Early gamma interferon production by natural killer cells is important in defense against murine listeriosis

  1991cited by this paper
• Presentation of Listeria monocytogenes to CD8+ T cells requires secretion of hemolysin and intracellular bacterial growth.

  1990cited by this paper
• Roles of CD4+ and CD8+ cells, and the effect of administration of recombinant murine interferon gamma in listerial infection

  1990cited by this paper
• Evidence that tumor necrosis factor has an important role in antibacterial resistance.

  1989cited by this paper
• Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria

  1989cited by this paper
• Gamma interferon limits access of Listeria monocytogenes to the macrophage cytoplasm

  1989cited by this paper
• Cloned Listeria monocytogenes specific non-MHC-restricted Lyt-2+ T cells with cytolytic and protective activity.

  1988cited by this paper
• T-cell subsets in delayed-type hypersensitivity, protection, and granuloma formation in primary and secondary Listeria infection in mice: superior role of Lyt-2+ cells in acquired immunity

  1988cited by this paper
• A T cell-independent mechanism of macrophage activation by interferon-gamma.

  1987cited by this paper
• Requirement of endogenous interferon-gamma production for resolution of Listeria monocytogenes infection.

  1985cited by this paper
• Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells

  1985cited by this paper
• Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

  1984cited by this paper
• Restriction in adoptive transfer of resistance to Listeria monocytogenes. II. Use of congenic and mutant mice show transfer to be H-2K restricted.

  1983cited by this paper
• IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement.

  1980cited by this paper
• Activated macrophages in congenitally athymic "nude mice" and in lethally irradiate mice.

  1975cited by this paper
• Macrophage activation in mice lacking thymus-derived (T) cells

  1975cited by this paper
• THE INFLUENCE OF IMMUNOLOGICALLY COMMITTED LYMPHOID CELLS ON MACROPHAGE ACTIVITY IN VIVO

  1969cited by this paper

• By dawn or dusk-how circadian timing rewrites bacterial infection outcomes.

  2025cites this paper
• The relationship between Listeria infections and host immune responses: Listeriolysin O as a potential target.

  2024cites this paper
• Antigen specific activation of cytotoxic CD8+ T cells by Staphylococcus aureus infected dendritic cells

  2023cites this paper
• Surface plasmon resonance and microscale thermophoresis approaches for determining the affinity of perforin for calcium ions

  2023cites this paper
• Hacking the Immune Response to Solid Tumors: Harnessing the Anti-Cancer Capacities of Oncolytic Bacteria

  2023cites this paper
• Caspase-7 activates ASM to repair gasdermin and perforin pores

  2022cites this paper
• Summary and comparison of the perforin in teleosts and mammals: A review

  2021cites this paper
• SAM50, a side door to the mitochondria: The case of cytotoxic proteases.

  2020cites this paper
• Mitochondrial Entry of Cytotoxic Proteases: A New Insight into the Granzyme B Cell Death Pathway

  2019cites this paper
• Innate and Adaptive Immune Responses during Listeria monocytogenes Infection

  2019cites this paper
• Local regulation of immune genes in rainbow trout (Oncorhynchus mykiss) naturally infected with Flavobacterium psychrophilum

  2019cites this paper
• Antigenic and functional profiles of a Lawsonia intracellularis protein that shows a flagellin-like trait and its immuno-stimulatory assessment

  2018cites this paper
• Neonatal influenza‐specific effector CTLs retain elevated CD31 levels at the site of infection and have decreased IFN‐γ production

  2018cites this paper
• Molecular mechanisms regulating CD8+ T cell differentiation following external cues

  2018cites this paper
• IFN-Gamma-Dependent and Independent Mechanisms of CD4+ Memory T Cell-Mediated Protection from Listeria Infection

  2018cites this paper
• Evaluation of IL2 and HLA on the Homeostasis and Function of Human CD4 and CD8 T Cells

  2017cites this paper
• Bacterial Virulence Regulation and Targets of CD8+ T Cell Immunity During Listeria monocytogenes Infection

  2017cites this paper
• Programmed cell death as a defence against infection

  2017cites this paper
• Mycobacterium tuberculosis Intracellular Reduces the Viability of Fas Ligand-Induced Apoptosis of Infected Human

  2017cites this paper
• Public Clonotypes and Convergent Recombination Characterize the Naïve CD8+ T-Cell Receptor Repertoire of Extremely Preterm Neonates

  2017cites this paper
• Time-dependent alterations in memory CD8 T cell function after infection

  2016cites this paper
• Immunomodulatory and cellular antioxidant activities of pure compounds from Teucrium ramosissimum Desf.

  2016cites this paper
• Visualization of granzyme B‐expressing CD8 T cells during primary and secondary immune responses to Listeria monocytogenes

  2015cites this paper
• Invariant Chain Linkage : Extending the Concept of monocytogenes Listeria Adenovirus-Based Vaccine against

  2015cites this paper
• Listeria monocytogenes: a model pathogen to study antigen-specific memory CD8 T cell responses

  2015cites this paper
• A BTLA-mediated bait and switch strategy permits Listeria expansion in CD8α(+) DCs to promote long-term T cell responses.

  2014cites this paper
• Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes.

  2014cites this paper
• Functional expression cloning identifies COX-2 as a suppressor of antigen-specific cancer immunity

  2014cites this paper
• Perinatal Listeria monocytogenes susceptibility despite preconceptual priming and maintenance of pathogen-specific CD8+ T cells during pregnancy

  2014cites this paper
• Immune responses during spontaneous control of HIV and AIDS: what is the hope for a cure?

  2014cites this paper
• Perforin: a key pore-forming protein for immune control of viruses and cancer.

  2014cites this paper
• Role of CD4(+) and CD8α(+) T cells in protective immunity against Edwardsiella tarda infection of ginbuna crucian carp, Carassius auratus langsdorfii.

  2014cites this paper
• Perforin and human diseases.

  2014cites this paper
• Establishment of a CCL19/CCL21 dual transgenic system for investigating the functions of T cell zone stromal cells

  2013cites this paper
• Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis

  2013cites this paper
• Adenovirus-Based Vaccine against Listeria monocytogenes: Extending the Concept of Invariant Chain Linkage

  2013cites this paper
• Local immune responses in tuberculosis : cytolytic effector functions at the site of mycobacterium tuberculosis Infection

  2013cites this paper
• Increasing Memory CD8+ T Cell Numbers Absence of Perforin Can Be Restored by Deficient Anti-Listerial Immunity in the

  2013cites this paper
• Memory CD8+ CTL after Reinfection A Novel Role of IL-15 in Early Activation of

  2013cites this paper
• Listeria monocytogenes Are Protective In Vivo Th1 Cells Specific for a Secreted Protein of

  2013cites this paper
• Strategies to improve gene expression and targeting for DNA vaccine development

  2013cites this paper
• Minicircle DNA is superior to plasmid DNA in eliciting antigen-specific CD8+ T-cell responses.

  2013cites this paper
• MicroRNA-directed program of cytotoxic CD8+ T-cell differentiation

  2013cites this paper
• The Role of Tim-3 Receptor in CD8+ T cells Cytotoxicity in Chronic HIV Infection

  2013cites this paper
• Bacteriain Minimal Killing of Bystander Activation of Antigen-Specific CD8 T Cells

  2013cites this paper
• ELISPOT Assay for Monitoring Cytotoxic T Lymphocytes (CTL) Activity in Cancer Vaccine Clinical Trials

  2012cites this paper
• Modulation of antigenic location converts chronic into acute infection by forcing CD8+ T cell recognition.

  2012cites this paper
• In Vivo Assessment of Natural Killer Cell Responses during Chronic Feline Immunodeficiency Virus Infection

  2012cites this paper
• Perforin- and Granzyme-Mediated Cytotoxic Effector Functions Are Essential for Protection against Francisella tularensis following Vaccination by the Defined F. tularensis subsp. novicida ΔfopC Vaccine Strain

  2012cites this paper
• A Review on Molecular Basis of the Role of Psychological Stress in the Development and Progression of Type 1 and Type 2 Diabetes Mellitus

  2012cites this paper
• Tim-3 Negatively Regulates Cytotoxicity in Exhausted CD8+ T Cells in HIV Infection

  2012cites this paper
• Innate-like CD4 T cells selected by thymocytes suppress adaptive immune responses against bacterial infections.

  2012cites this paper
• Role of NK cells in DC-based immunotherapy of melanoma

  2011cites this paper
• Pathogenesis of Hepatitis B Virus (HBV)-Mediated Liver Injury

  2011cites this paper
• CD8+ T Cells Primed in the Periphery Provide Time-Bound Immune-Surveillance to the Central Nervous System

  2011cites this paper
• Views of immunology: effector T cells

  2011cites this paper
• Toxoplasma gondii inhibits granzyme B-mediated apoptosis by the inhibition of granzyme B function in host cells.

  2011cites this paper
• Cellular and molecular characterisation of familial haemophagocytic lymphohistiocytosis type 1

  2011cites this paper
• Development and function of thymocyte-selected CD4 T cells

  2010cites this paper
• Dissertation zur Erlangung des Doktorgrades der Fakultät für Chemie und Pharmazie der Ludwig-Maximilians-Universität München Pattern recognition receptors are subset specific in dendritic cells In vivo quantitative proteomic investigations using label-free analysis and the SILAC mouse

  2009cites this paper
• Involvement of CD252 (CD134L) and IL-2 in the Expression of Cytotoxic Proteins in Bacterial- or Viral-Activated Human T Cells1

  2009cites this paper
• Pattern recognition receptors are subset specific in dendritic cells

  2009cites this paper
• Tissue distribution, antigen specificity and effector functions of γδ T cells in human diseases

  2009cites this paper
• CD8+ T Cells Restrict Yersinia pseudotuberculosis Infection: Bypass of Anti-Phagocytosis by Targeting Antigen-Presenting Cells

  2009cites this paper
• The Role of Natural Killer Cells in Resistance to the Intracellular Bacterium Listeria monocytogenes in Rats

  2009cites this paper
• Protective CD8+ T cells against Plasmodium liver stages: immunobiology of an ‘unnatural’ immune response

  2008cites this paper
• IL‐10 and the resolution of infections

  2008cites this paper
• Granzymes Drive a Rapid Listeriolysin O-Induced T Cell Apoptosis1

  2008cites this paper
• Involvement of CD4+ T cells and macrophages in acquired protection against infection with Sporothrix schenckii in mice: Cell-mediated immunity against S. schenckii

  2008cites this paper
• Auswirkungen von kurzzeitigem psychischem Laborstress auf die Verteilung von T-Zell-Subpopulationen und Effektormechanismen des peripher zirkulierenden T-Zell-Pools

  2008cites this paper
• Innate immunity to intracellular bacterial infections

  2008cites this paper
• Apoptosis induced by the lymphocyte effector molecule perforin.

  2007cites this paper
• Role of the Immune Response in Hepatitis B

  2007cites this paper
• Adaptive Immunity to Listeria monocytogenes

  2007cites this paper
• Innate and adaptive immune responses to Listeria monocytogenes: a short overview.

  2007cites this paper
• Characterization of the CD8 T cell response to Salmonella typhimurium infection in mice

  2007cites this paper
• Immune Evasion and Modulation by Listeria monocytogenes

  2007cites this paper
• Listeria monocytogenes : pathogenesis and host response

  2007cites this paper
• Mechanisms of IFN-gamma-mediated Resistance against Development of Toxoplasmic Encephalitis

  2006cites this paper
• Characterisation of CD8 T cells in mucosa associated lymphoid tissue : Implications for immune control of HIV-1 infection

  2006cites this paper
• Regulation of Apoptosis by Gram-Positive Bacteria: Mechanistic Diversity and Consequences for Immunity.

  2006cites this paper
• UVA1 radiation (340-400 nm) interferes with the perforin-granule system of CD8hi+ cytotoxic T lymphocytes in vitro.

  2006cites this paper
• Fatal Recall Responses Mediated by CD8 T cells during Intracellular Bacterial Challenge Infection1

  2006cites this paper
• Current status of vaccine development against Theileria parasites

  2006cites this paper
• Untersuchungen zur Effizienz von DNA-und Protein-Trägersystemen zur Induktion von zellulären Immunantworten durch Dendritische Zellen

  2006cites this paper
• Hemophagocytic lymphohistiocytosis: Diagnosis, pathophysiology, treatment, and future perspectives

  2006cites this paper
• DifferentialRequirements for Soluble and Transmembrane Tumor Necrosis Factor in theImmunological Control of Primary and Secondary Listeria monocytogenesInfection

  2006cites this paper
• Listeria monocytogenes Infection of Mice: an Elegant Probe To Dissect Innate and T-Cell Immune Responses

  2006cites this paper
• Elevated percentage of perforin positive cells in active pulmonary tuberculosis.

  2006cites this paper
• A Novel Role of IL-15 in Early Activation of Memory CD8+ CTL after Reinfection1

  2005cites this paper
• Dietary ( n-3 ) Polyunsaturated Fatty Acids Do Not Affect the In Vivo Development and Function of Listeria-Specific CD 4 and CD 8 Effector and Memory / Effector T Cells in Mice 1 , 2

  2005cites this paper
• Dietary (n-3) polyunsaturated fatty acids do not affect the in vivo development and function of Listeria-specific CD4+ and CD8+ effector and memory/effector T cells in mice.

  2005cites this paper
• Simultaneous Th1-Type Cytokine Expression Is a Signature of Peritoneal CD4+ Lymphocytes Responding to Infection with Listeria monocytogenes 1

  2005cites this paper
• Perforin and lymphohistiocytic proliferative disorders

  2005influential citation
• Chronic fatigue syndrome is associated with diminished intracellular perforin

  2005cites this paper
• Cytotoxic activity of murine resident peritoneal cells against Listeria monocytogenes-infected hepatocytes in vitro.

  2005cites this paper
• Comparison of DNA delivery systems for vaccination against intracellular bacteria

  2004cites this paper
• Effector and memory CD8+ T cells as seen in immunity to malaria

  2004cites this paper
• UVA radiation induces suppression of perforin-granule release from CD8(hi+) cytotoxic T lymphocytes ex vivo.

  2004cites this paper
• MHC class Ia–restricted memory T cells inhibit expansion of a nonprotective MHC class Ib (H2-M3)–restricted memory response

  2004cites this paper