The Physical Properties of the Capsular Polysaccharides from Cryptococcus neoformans Suggest Features for Capsule Construction*

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Biological Chemistry

• Publication date

  2006-01-27

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1074/jbc.M509465200PMID 16278213
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Radiological Studies Reveal Radial Differences in the Architecture of the Polysaccharide Capsule of Cryptococcus neoformans

  2005cited by this paper
• Cryptococcus neoformans Capsular Glucuronoxylomannan Induces Expression of Fas Ligand in Macrophages1

  2005cited by this paper
• Phenotypic Switching of Cryptococcus neoformans Can Produce Variants That Elicit Increased Intracranial Pressure in a Rat Model of Cryptococcal Meningoencephalitis

  2005cited by this paper
• Curdlan and other bacterial (1-->3)-beta-D-glucans.

  2005cited by this paper
• Capsule structure changes associated with Cryptococcus neoformans crossing of the blood-brain barrier.

  2005cited by this paper
• Glucuronoxylomannan, a microbial compound, regulates expression of costimulatory molecules and production of cytokines in macrophages.

  2005cited by this paper
• Curdlan and other bacterial (1→3)-β-d-glucans

  2005cited by this paper
• Cryptococcus neoformans CAP59 (or Cap59p) Is Involved in the Extracellular Trafficking of Capsular Glucuronoxylomannan

  2004cited by this paper
• Glucuronoxylomannan, the Major Capsular Polysaccharide of Cryptococcus neoformans, Inhibits the Progression of Group B Streptococcal Arthritis

  2004cited by this paper
• Cryptococcus neoformans capsule biosynthesis and regulation.

  2004cited by this paper
• Molecular architecture of the Cryptococcus neoformans capsule

  2004cited by this paper
• O-Acetylation of Cryptococcal Capsular Glucuronoxylomannan Is Essential for Interference with Neutrophil Migration1

  2004cited by this paper
• Unexpected Diversity in the Fine Specificity of Monoclonal Antibodies That Use the Same V Region Gene to Glucuronoxylomannan of Cryptococcus neoformans1

  2004cited by this paper
• Pneumonia Due to Cryptococcus neoformans in a Patient Receiving Infliximab: Possible Zoonotic Transmission From a Pet Cockatiel

  2004cited by this paper
• Cavitating pneumonia after treatment with infliximab and prednisone

  2004cited by this paper
• Pulmonary cryptococcosis after initiation of anti-tumor necrosis factor-alpha therapy.

  2003cited by this paper
• If Homogalacturonan Were a Side Chain of Rhamnogalacturonan I. Implications for Cell Wall Architecture1

  2003cited by this paper
• The polysaccharide capsule of Cryptococcus neoformans interferes with human dendritic cell maturation and activation

  2003cited by this paper
• Macromolecular and solution properties of Cepacian: the exopolysaccharide produced by a strain of Burkholderia cepacia isolated from a cystic fibrosis patient.

  2003cited by this paper
• Pulmonary Cryptococcosis After Initiation of Anti-Tumor Necrosis Factor-α Therapy

  2003cited by this paper
• Cryptococcosis.

  2002cited by this paper
• Spatial and temporal sequence of capsule construction in Cryptococcus neoformans

  2001cited by this paper
• Polysaccharides, mimotopes and vaccines for fungal and encapsulated pathogens.

  2001cited by this paper
• Toll-Like Receptor 4 Mediates Intracellular Signaling Without TNF-α Release in Response to Cryptococcus neoformans Polysaccharide Capsule1

  2001cited by this paper
• Immunoglobulin M Efficacy Against Cryptococcus neoformans: Mechanism, Dose Dependence, and Prozone-Like Effects in Passive Protection Experiments1

  2001cited by this paper
• Cas1p is a membrane protein necessary for the O‐acetylation of the Cryptococcus neoformans capsular polysaccharide

  2001cited by this paper
• Dynamic changes in the morphology of Cryptococcus neoformans during murine pulmonary infection.

  2001cited by this paper
• Phenotypic switching of Cryptococcus neoformans occurs in vivo and influences the outcome of infection.

  2001cited by this paper
• Cryptococcus neoformans Is a Facultative Intracellular Pathogen in Murine Pulmonary Infection

  2000cited by this paper
• In Vitro and In Vivo Stability a Cryptococcus neoformans Glucuronoxylomannan Epitope That Elicits Protective Antibodies

  1999cited by this paper
• Phenotypic Switching in Cryptococcus neoformansResults in Changes in Cellular Morphology and Glucuronoxylomannan Structure

  1999cited by this paper
• In vitro and in vivo stability of a Cryptococcus neoformans [corrected] glucuronoxylomannan epitope that elicits protective antibodies.

  1999cited by this paper
• Phenotypic switching in the human pathogenic fungus Cryptococcus neoformans is associated with changes in virulence and pulmonary inflammatory response in rodents.

  1998cited by this paper
• Structural characterization of the galactoxylomannan of Cryptococcus neoformans Cap67.

  1998cited by this paper
• Effect of immune mechanisms on the pharmacokinetics and organ distribution of cryptococcal polysaccharide.

  1998cited by this paper
• Mechanism of action of antibody to capsular polysaccharide in Cryptococcus neoformans infection.

  1998cited by this paper
• Cryptococcus neoformans Chemotyping by Quantitative Analysis of 1H Nuclear Magnetic Resonance Spectra of Glucuronoxylomannans with a Computer-Simulated Artificial Neural Network

  1998cited by this paper
• Organ-Dependent Variation of Capsule Thickness inCryptococcus neoformans during Experimental Murine Infection

  1998cited by this paper
• Epitope Location in the Cryptococcus neoformans Capsule Is a Determinant of Antibody Efficacy

  1997cited by this paper
• Effect of serum IgG1 to Cryptococcus neoformans glucuronoxylomannan on murine pulmonary infection.

  1997cited by this paper
• Atlas of Clinical Fungi

  1997cited by this paper
• Mass spectrometric composition and molecular mass of Lumbricus terrestris hemoglobin: a refined model of its quaternary structure.

  1996cited by this paper
• Downregulation by cryptococcal polysaccharide of tumor necrosis factor alpha and interleukin-1 beta secretion from human monocytes

  1995cited by this paper
• Monoclonal antibodies to Cryptococcus neoformans capsular polysaccharide modify the course of intravenous infection in mice

  1994cited by this paper
• An agarose gel electrophoretic method for analysis of hyaluronan molecular weight distribution.

  1994cited by this paper
• Prevalence in Cryptococcus neoformans strains of a polysaccharide epitope which can elicit protective antibodies.

  1994cited by this paper
• Mass analysis of biological macromolecular complexes by STEM

  1994cited by this paper
• Ultrastructural study of hepatic granulomas induced byCryptococcus neoformans by quick-freezing and deep-etching method

  1993cited by this paper
• Molecular characterization of the humoral responses to Cryptococcus neoformans infection and glucuronoxylomannan-tetanus toxoid conjugate immunization

  1993cited by this paper
• Galactoxylomannans of Cryptococcus neoformans

  1992cited by this paper
• Monoclonal antibody based ELISAs for cryptococcal polysaccharide.

  1992cited by this paper
• Antibodies elicited by a Cryptococcus neoformans-tetanus toxoid conjugate vaccine have the same specificity as those elicited in infection.

  1992cited by this paper
• Cryptococcus neoformans serotype A glucuronoxylomannan-protein conjugate vaccines: synthesis, characterization, and immunogenicity

  1991cited by this paper
• Glucuronoxylomannan of Cryptococcus neoformans serotype B: structural analysis by gas-liquid chromatography-mass spectrometry and 13C-nuclear magnetic resonance spectroscopy.

  1991cited by this paper
• The mouse antibody response to infection with Cryptococcus neoformans: VH and VL usage in polysaccharide binding antibodies

  1991cited by this paper
• Definitions of terms relating to individual macromolecules, their assemblies, and dilute polymer solutions (Recommendations 1988)

  1989cited by this paper
• Localization of mannoprotein in Cryptococcus neoformans

  1989cited by this paper
• Effect of Hypertonic Solutes Upon the Polysaccharide Capsule in Cryptococcus neoformans

  1989cited by this paper
• Oral, topical and parenteral antifungal treatment with itraconazole in normal and in immunocompromised animals.

  1989cited by this paper
• Oral, Topical and Parenteral Antifungal Treatment with Itraconazole in Normal and in Immunocompromised Animals

  1989cited by this paper
• Serological, electrophoretic, and biological properties of Cryptococcus neoformans antigens

  1988cited by this paper
• Structure determination of Cryptococcus neoformans serotype A-variant glucuronoxylomannan by 13C-n.m.r. spectroscopy.

  1988cited by this paper
• Protection of mice against experimental cryptococcosis by anti-Cryptococcus neoformans monoclonal antibody

  1987cited by this paper
• X-Ray Diffraction Study on (1→3)-α-D-Mannan Dihydrate.

  1986cited by this paper
• Binding of cryptococcal polysaccharide to Cryptococcus neoformans

  1984cited by this paper
• A galactoxylomannan antigen of Cryptococcus neoformans serotype A

  1982cited by this paper
• Cryptococcal culture filtrate antigen for detection of delayed-type hypersensitivity in cryptococcosis

  1979cited by this paper
• Non-encapsulated variant of Cryptococcus neoformans. II. Surface receptors for cryptococcal polysaccharide and their role in inhibition of phagocytosis by polysaccharide

  1977cited by this paper
• Nonencapsulated Variant of Cryptococcus neoformans I. Virulence Studies and Characterization of Soluble Polysaccharide

  1971cited by this paper
• NATURAL HOST RESISTANCE TO INFECTION WITH CRYPTOCOCCUS NEOFORMANS. III. THE EFFECT OF CRYPTOCOCCAL POLYSACCHARIDE UPON THE PHYSIOLOGY OF THE RETICULOENDOTHELIAL SYSTEM OF LABORATORY ANIMALS.

  1964cited by this paper
• COLORIMETRIC METHOD FOR DETER-MINATION OF SUGAR AND RELATED SUBSTANCE

  1956cited by this paper
• The Scattering of Light and the Radial Distribution Function of High Polymer Solutions

  1948cited by this paper

• Comparative analysis of glucuronoxylomannogalactan (GXMGal) and glucuronoxylomannan (GXM) antibody responses and their associations with cryptococcal disease status in people living with HIV.

  2025cites this paper
• The Role of Nutritional Environment in Cryptococcus gattii Titan Cells’ Ultrastructure, Biophysical Properties, Molecular Features, and Virulence in Cryptococcosis

  2025cites this paper
• The Capsular Polysaccharides GXM and GXMGal from Cryptococcus neoformans Modulate Macrophages Infected with Leishmania major

  2025cites this paper
• Unexpected variability in laboratory and clinical assays used to quantify Cryptococcus neoformans polysaccharide.

  2025cites this paper
• Unexpected variability in laboratory and clinical assays used to quantify Cryptococcus neoformans polysaccharide

  2025cites this paper
• Role of glucuronoxylomannan and steryl glucosides in protecting against cryptococcosis

  2025influential citation
• Impact of sodium lactate as a carbon source in the polysaccharide of Cryptococcus species

  2025cites this paper
• Molecular Distinction of Cell Wall and Capsular Polysaccharides in Encapsulated Pathogens by In Situ Magic-Angle Spinning NMR Techniques.

  2025cites this paper
• The buoyancy of cryptococcal cells and its implications for transport and persistence of Cryptococcus in aqueous environments

  2024cites this paper
• Elements of dissemination in cryptococcosis

  2024cites this paper
• A holistic review on Cryptococcus neoformans.

  2022cites this paper
• Lyophilization induces physicochemical alterations in cryptococcal exopolysaccharide

  2022cites this paper
• Cryptococcus: History, Epidemiology and Immune Evasion

  2022cites this paper
• Influence of Pathogen Carbon Metabolism on Interactions With Host Immunity

  2022cites this paper
• Hidden in plain sight: urinary Cryptococcus neoformans missed by routine diagnostics in a patient with acute leukemia

  2022cites this paper
• Histoplasma capsulatum Glycans From Distinct Genotypes Share Structural and Serological Similarities to Cryptococcus neoformans Glucuronoxylomannan

  2021cites this paper
• A Novel, Inexpensive In-House Immunochromatographic Strip Test for Cryptococcosis Based on the Cryptococcal Glucuronoxylomannan Specific Monoclonal Antibody 18B7

  2021cites this paper
• Glycans of the Pathogenic Yeast Cryptococcus neoformans and Related Opportunities for Therapeutic Advances

  2021cites this paper
• How do terminal modifications of short designed IIKK peptide amphiphiles affect their antifungal activity and biocompatibility?

  2021cites this paper
• Infections by Cryptococcus species

  2021cites this paper
• Cryptococcus neoformans capsule regrowth experiments reveal dynamics of enlargement and architecture

  2021cites this paper
• Cryptococcus neoformans Capsular GXM Conformation and Epitope Presentation: A Molecular Modelling Study

  2020cites this paper
• Let it bud: an ultrastructural study of Cryptococcus neoformans surface during budding events

  2020cites this paper
• University of Birmingham The Diverse Roles of Monocytes in Cryptococcosis

  2020cites this paper
• Structure and Foaming Properties of Viscous Exopolysaccharides from a Wild Grape-Associated Basidiomycetous Yeast Papiliotrema flavescens Formerly Known as Cryptococcus flavescens

  2020cites this paper
• Structure and foaming properties of viscous exopolysaccharides from a wild grape-associated basidiomycetous yeast Papiliotrema flavescens formerly known as Cryptococcus flavescens.

  2020cites this paper
• The Diverse Roles of Monocytes in Cryptococcosis

  2020cites this paper
• Biology and Function of Exo-Polysaccharides from Human Fungal Pathogens

  2020cites this paper
• Rheological properties of cryptococcal polysaccharide change with fiber size, antibody binding and temperature.

  2019cites this paper
• Dectin‐2‐mediated signaling triggered by the cell wall polysaccharides of Cryptococcus neoformans

  2019cites this paper
• Exploring Cryptococcus neoformans capsule structure and assembly with a hydroxylamine-armed fluorescent probe

  2019cites this paper
• Virulence Factors in Sporothrix schenckii, One of the Causative Agents of Sporotrichosis.

  2019cites this paper
• Cryptococcus neoformans Secretes Small Molecules That Inhibit IL-1β Inflammasome-Dependent Secretion

  2019cites this paper
• The Capsule of Cryptococcus neoformans Modulates Phagosomal pH through Its Acid-Base Properties

  2018cites this paper
• Potential targets for next generation antimicrobial glycoconjugate vaccines

  2018cites this paper
• Unraveling synthesis of the cryptococcal cell wall and capsule

  2018cites this paper
• Titan cell production in Cryptococcus neoformans reshapes the cell wall and capsule composition during infection

  2018cites this paper
• The capsule of Cryptococcus neoformans

  2018cites this paper
• Immunological Identification of Fungal Species.

  2017cites this paper
• Current Progress in Medical Mycology

  2017cites this paper
• Antimicrobial Octapeptin C4 Analogues Active against Cryptococcus Species

  2017cites this paper
• Nano-exploration of organic conditioning film formed on polymeric surfaces exposed to drinking water.

  2017cites this paper
• Cryptococcus and Cryptococcosis

  2017cites this paper
• Nutritional Requirements and Their Importance for Virulence of Pathogenic Cryptococcus Species

  2017cites this paper
• Cryptococcus neoformans capsular polysaccharides form branched and complex filamentous networks viewed by high-resolution microscopy.

  2016cites this paper
• What makes Cryptococcus gattii a pathogen?

  2016cites this paper
• , Assembly Cell Wall Remodeling and Capsule Pbx Proteins in Cryptococcus neoformans

  2016cites this paper
• Identification of QTLs Associated with Virulence Related Traits and Drug Resistance in Cryptococcus neoformans

  2016cites this paper
• Pathogen-Specific Adaptations to Conserved Signaling Pathways in Cryptococcus neoformans

  2016cites this paper
• Activity of Scorpion Venom-Derived Antifungal Peptides against Planktonic Cells of Candida spp. and Cryptococcus neoformans and Candida albicans Biofilms

  2016cites this paper
• Synthetic Peptides as an Alternative Tool for the Diagnosis of Cryptococcosis

  2016cites this paper
• Virulence-Associated Enzymes of Cryptococcus neoformans

  2015cites this paper
• Proteomic profiling of the pathogenic fungus Cryptococcus neoformans upon regulation of the cyclic-AMP/protein kinase A signaling pathway

  2015cites this paper
• Antiviral, Antifungal and Antibacterial Activities of a BODIPY-Based Photosensitizer

  2015cites this paper
• The Cryptococcus neoformans capsule: lessons from the use of optical tweezers and other biophysical tools

  2015cites this paper
• A Role for LHC1 in Higher Order Structure and Complement Binding of the Cryptococcus neoformans Capsule

  2014cites this paper
• Pbx Proteins in Cryptococcus neoformans Cell Wall Remodeling and Capsule Assembly

  2014cites this paper
• Cryptococcus neoformans Hyperfilamentous Strain Is Hypervirulent in a Murine Model of Cryptococcal Meningoencephalitis

  2014cites this paper
• Caracterização do efeito antifúngico de peptídeos presentes na peçonha de escorpiões em linhagens de Cryptococcus neoformans

  2014cites this paper
• Drinking water biofilm cohesiveness changes under chlorination or hydrodynamic stress.

  2014cites this paper
• Temporal Behavior of Capsule Enlargement by Cryptococcus neoformans

  2013cites this paper
• Cryptococcus neoformans Ex Vivo Capsule Size Is Associated With Intracranial Pressure and Host Immune Response in HIV-associated Cryptococcal Meningitis

  2013cites this paper
• Utilização de métodos de bioimagem para a análise ex vivo da infecção causada por cryptococcus gattii

  2013cites this paper
• Quorum Sensing-Mediated, Cell Density-Dependent Regulation of Growth and Virulence in Cryptococcus neoformans

  2013cites this paper
• A simple SPR-based method for the quantification of the effect of potential virus inhibitors.

  2013cites this paper
• Cryptococcus neoformans transcriptional regulation of the host-pathogen interface

  2013cites this paper
• Allergen1 regulates polysaccharide structure in Cryptococcus neoformans

  2013cites this paper
• Temporal Behavior of Capsule Enlargement for

  2013cites this paper
• Level Size Is Mediated at the Polymer Cryptococcus neoformans Regulation of

  2013cites this paper
• Unusual Galactofuranose Modification of a Capsule Polysaccharide in the Pathogenic Yeast Cryptococcus neoformans *

  2013cites this paper
• Elucidating the immunological function of the Cryptococcus neoformans capsule.

  2013cites this paper
• The Cryptococcus neoformans Capsule: a Sword and a Shield

  2012cites this paper
• Capsular Material of Cryptococcus neoformans: Virulence and Much More

  2012cites this paper
• Fungal Melanins Differ in Planar Stacking Distances

  2012cites this paper
• Transplacental transmission of Cryptococcus neoformans to an HIV-exposed premature neonate

  2012cites this paper
• Variable Region Identical Immunoglobulins Differing in Isotype Express Different Paratopes*

  2012cites this paper
• Induction of Cryptococcus laurentii α-galactosidase

  2012cites this paper
• Sword and a Shield The Cryptococcus neoformans Capsule: a

  2012cites this paper
• Capsules from Pathogenic and Non-Pathogenic Cryptococcus spp. Manifest Significant Differences in Structure and Ability to Protect against Phagocytic Cells

  2012cites this paper
• Universidade Federal do Rio Grande do Sul Centro de Biotecnologia Programa de Pós-Graduação em Biologia Celular e Molecular

  2012cites this paper
• Análise de alterações morfológicas associadas a mutação de tropomiosina em Cryptococcus gattii

  2012cites this paper
• Inhibition of HIV entry by extracellular glucuronoxylomannan of Cryptococcus neoformans.

  2012cites this paper
• Multiple Disguises for the Same Party: The Concepts of Morphogenesis and Phenotypic Variations in Cryptococcus neoformans

  2011influential citation
• Cryptococcus neoformans galactoxylomannan is a potent negative immunomodulator, inspiring new approaches in anti-inflammatory immunotherapy.

  2011cites this paper
• Evidence for branching in cryptococcal capsular polysaccharides and consequences on its biological activity

  2011cites this paper
• Chronological Aging Is Associated with Biophysical and Chemical Changes in the Capsule of Cryptococcus neoformans

  2011cites this paper
• Expression and Characterization of Cryptococcus neoformans Recombinant App1

  2011cites this paper
• Glucuronoxylomannan from Cryptococcus neoformans Down-regulates the Enzyme 6-Phosphofructo-1-kinase of Macrophages*

  2011cites this paper
• Evaluation of Cryptococcus neoformans galactoxylomannan-protein conjugate as vaccine candidate against murine cryptococcosis.

  2011cites this paper
• The Architecture and Antigenic Composition of the Polysaccharide Capsule

  2011cites this paper
• Biosynthesis and Genetics of the Cryptococcus Capsule

  2011cites this paper
• Avaliação do sistema complemento e produção de anticorpos de pacientes HIV negativos com neurocriptococose

  2011cites this paper
• Fungal Polysaccharides: Biological Activity Beyond the Usual Structural Properties

  2011influential citation
• Cryptococcus neoformans responds to mannitol by increasing capsule size in vitro and in vivo

  2010cites this paper
• Galactoxylomannans from Cryptococcus neoformans Varieties neoformans and grubii Are Structurally and Antigenically Variable

  2010influential citation
• Circular Dichroism reveals evidence of coupling between immunoglobulin constant and variable region secondary structure.

  2010cites this paper
• Microbial polysaccharide: new insights for treating autoimmune diseases.

  2010cites this paper
• Survival of yeasts stored after freeze-drying or liquid-drying.

  2010cites this paper
• Vesicular transport across the fungal cell wall.

  2009cites this paper
• Galactoxylomannan-Mediated Immunological Paralysis Results from Specific B Cell Depletion in the Context of Widespread Immune System Damage12

  2009cites this paper