Apoptotic, non-apoptotic, and anti-apoptotic pathways of tumor necrosis factor signalling.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Biochemical Pharmacology

• Publication date

  1998-10-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0006-2952(98)00154-3PMID 9776301
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The TNF Receptor I-Associated Protein TRADD Signals Cell Death and NF-KB Activation

  2003cited by this paper
• Nuclear Factor kB-independent Cytoprotective Pathways Originating at Tumor Necrosis Factor Receptor-associated Factor 2*

  1998cited by this paper
• MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1

  1997cited by this paper
• Tumor Necrosis Factor (TNF) Receptor 1 Signaling Downstream of TNF Receptor-associated Factor 2

  1997cited by this paper
• A20 inhibits NF-kappaB activation independently of binding to 14-3-3 proteins.

  1997cited by this paper
• Activation of SAPK/JNK by TNF Receptor 1 Through a Noncytotoxic TRAF2-Dependent Pathway

  1997cited by this paper
• Tumor necrosis factor (TNF) receptor 1 signaling downstream of TNF receptor-associated factor 2. Nuclear factor kappaB (NFkappaB)-inducing kinase requirement for activation of activating protein 1 and NFkappaB but not of c-Jun N-terminal kinase/stress-activated protein kinase.

  1997cited by this paper
• A20 Inhibits NF-κB Activation Independently of Binding to 14-3-3 Proteins

  1997cited by this paper
• Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice.

  1997cited by this paper
• TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival.

  1997cited by this paper
• Cell death induction by TNF: a matter of self control.

  1997cited by this paper
• Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2.

  1997cited by this paper
• Tumor necrosis factor alpha-induced activation of c-jun N-terminal kinase is mediated by TRAF2.

  1997cited by this paper
• Tumor necrosis factor α‐induced activation of c‐jun N‐terminal kinase is mediated by TRAF2

  1997cited by this paper
• I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction.

  1996cited by this paper
• A20 Blocks Endothelial Cell Activation through a NF-κB-dependent Mechanism*

  1996cited by this paper
• Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death.

  1996cited by this paper
• Suppression of TNF-alpha-induced apoptosis by NF-kappaB.

  1996cited by this paper
• TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation.

  1996cited by this paper
• Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death.

  1996cited by this paper
• The NF-kappa B and I kappa B proteins: new discoveries and insights.

  1996cited by this paper
• TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways.

  1996cited by this paper
• Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death

  1996cited by this paper
• FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.

  1996cited by this paper
• TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex.

  1996cited by this paper
• The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation.

  1996cited by this paper
• Does this have a familiar RING?

  1996cited by this paper
• Transducers of life and death: TNF receptor superfamily and associated proteins.

  1996cited by this paper
• Rectal pH measurement in tracking cardiac performance in a hemorrhagic shock model.

  1996cited by this paper
• A20 zinc finger protein inhibits TNF and IL-1 signaling.

  1996cited by this paper
• Recent advances in tumor necrosis factor and CD40 signaling.

  1996cited by this paper
• RIP mediates tumor necrosis factor receptor 1 activation of NF‐kappaB but not Fas/APO‐1‐initiated apoptosis.

  1996cited by this paper
• Anatomy of TRAF2

  1996cited by this paper
• TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB.

  1996cited by this paper
• An essential role for NF-kappaB in preventing TNF-alpha-induced cell death.

  1996cited by this paper
• Suppression of TNF-α-Induced Apoptosis by NF-κB

  1996cited by this paper
• An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

  1996cited by this paper
• TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB

  1996cited by this paper
• THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

  1996cited by this paper
• FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.

  1995cited by this paper
• Cytotoxicity‐dependent APO‐1 (Fas/CD95)‐associated proteins form a death‐inducing signaling complex (DISC) with the receptor.

  1995cited by this paper
• Two tumour necrosis factor receptors: structure and function.

  1995cited by this paper
• Involvement of CRAF1, a relative of TRAF, in CD40 signaling

  1995cited by this paper
• RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death.

  1995cited by this paper
• A Novel Protein That Interacts with the Death Domain of Fas/APO1 Contains a Sequence Motif Related to the Death Domain (*)

  1995cited by this paper
• The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation.

  1995cited by this paper
• TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

  1995cited by this paper
• Activation of the B-cell Surface Receptor CD40 Induces A20, a Novel Zinc Finger Protein That Inhibits Apoptosis (*)

  1995cited by this paper
• A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor.

  1994cited by this paper
• Signal transduction by tumor necrosis factor mediated by JNK protein kinases

  1994cited by this paper
• A novel domain within the 55 kd TNF receptor signals cell death.

  1993cited by this paper
• Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation.

  1993cited by this paper
• Human T cell leukemia virus type I Tax and phorbol 12-myristate 13-acetate induce expression of the A20 zinc finger protein by distinct mechanisms involving nuclear factor kappa B.

  1993cited by this paper
• Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements.

  1992cited by this paper
• The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa B.

  1992cited by this paper
• The pathophysiology of tumor necrosis factors.

  1992cited by this paper
• The A20 zinc finger protein protects cells from tumor necrosis factor cytotoxicity.

  1992cited by this paper
• Zinc fingers and other metal-binding domains. Elements for interactions between macromolecules.

  1990cited by this paper
• Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin.

  1990cited by this paper

• The dichotomic role of cytokines in aging

  2024cites this paper
• Molecular and Cellular Mechanisms for PRRSV Pathogenesis and Host Response to Infection

  2020cites this paper
• Activation of sialoadhesin down-regulates the levels of innate antiviral cytokines in porcine alveolar macrophages in vitro.

  2020cites this paper
• Sphingolipids: Functional and Biological Aspects in Mammals, Plants, and Fungi

  2020cites this paper
• Neuronalinjury and roles of apoptosis and autophagy in a neonatal rat model of hypoxia-ischemia-induced periventricular leukomalacia

  2018cites this paper
• Platycodin D Suppresses Type 2 Porcine Reproductive and Respiratory Syndrome Virus In Primary and Established Cell Lines

  2018cites this paper
• Design, development and experimental trialof a tailored cytotoxic T-cell vaccine againstPorcine Reproductive and RespiratorySyndrome Virus-2

  2017cites this paper
• StIKKing it to a death kinase: IKKs prevent TNF-α-induced cell death by phosphorylating RIPK1.

  2016cites this paper
• Regulation o f N F - k B by the HTLV-1 Tax Protein

  2016cites this paper
• Exploring the potential of glycogen synthase kinase-3 (GSK3) mediated therapy in castrate-resistant prostate cancer

  2016cites this paper
• Intracellular trafficking of AIP56, a bacterial AB toxin trageting NF - kB

  2015cites this paper
• Time lapse microscopy observation of cellular structural changes and image analysis of drug treated cancer cells to characterize the cellular heterogeneity

  2015cites this paper
• Involvement of the TNF-α/TGF-β/IDO axis in IVIg-induced immune tolerance.

  2015cites this paper
• Regulation and evasion of antiviral immune responses by porcine reproductive and respiratory syndrome virus

  2014cites this paper
• Attenuation by Statins of Membrane Raft-Redox Signaling in Coronary Arterial Endothelium

  2013cites this paper
• Expressions of tumor necrosis factor-α, its receptor I, II and receptor-associated factor 2 in the porcine corpus luteum during the estrous cycle and early pregnancy

  2013cites this paper
• NEMO Inhibits Programmed Necrosis in an NFκB-Independent Manner by Restraining RIP1

  2012cites this paper
• NFκB and ubiquitination: partners in disarming RIPK1-mediated cell death

  2012cites this paper
• TRAIL death receptor 4 signaling via lysosome fusion and membrane raft clustering in coronary arterial endothelial cells: evidence from ASM knockout mice

  2012cites this paper
• Superoxide dismutase 3-mediated cell survival and proliferation

  2012cites this paper
• Neuroprotection Caused by Hyperoxia Preconditioning in Animal Stroke Models

  2011cites this paper
• Novel therapeutic strategies to target RCAS1, which induces apoptosis via ectodomain shedding.

  2011cites this paper
• Membrane raft-lysosome redox signalling platforms in coronary endothelial dysfunction induced by adipokine visfatin.

  2011cites this paper
• Neuroprotection Caused by Hyperoxia Preconditioning in Animal Stroke Models

  2011cites this paper
• RIP1 comes back to life as a cell death regulator in TNFR1 signaling

  2011cites this paper
• Triggering role of acid sphingomyelinase in endothelial lysosome-membrane fusion and dysfunction in coronary arteries.

  2010cites this paper
• Chronicles of a death foretold: Dual sequential cell death checkpoints in TNF signaling

  2010cites this paper
• Receptor-binding cancer antigen expressed on SiSo cells induces apoptosis via ectodomain shedding.

  2010cites this paper
• Inhibition of cytokine signaling in human retinal endothelial cells through downregulation of sphingomyelinases by docosahexaenoic acid.

  2010cites this paper
• Influence de l'immunité et des facteurs angiogéniques sur la croissance des glioblastomes

  2010cites this paper
• Regulation Of Chromatin Structre And Transcription By Poly(Adp-Ribose) Polymerase -1

  2010cites this paper
• Mechanismen der posttraumatischen Immundepression

  2010cites this paper
• Antigen Specific Tolerance Inhibits Autoimmune Uveitis in Pre-sensitized Animals via Deletion and CD4+CD25+ T-Regulatory Cells

  2009cites this paper
• Pathophysiology of Krabbe disease

  2009influential citation
• Immune-mediated liver diseases: programmed cell death ligands and circulating apoptotic markers

  2009cites this paper
• Ceramide-enriched membrane domains--structure and function.

  2009cites this paper
• p38 mitogen‐activated protein kinase targets the production of proinflammatory endothelial microparticles

  2009cites this paper
• Dual roles of tumor necrosis factor-α receptor-1 in a mouse model of hindlimb ischemia

  2009cites this paper
• Changes in Apoptotic Gene Expression Induced by DNA Cross-Linkers

  2009cites this paper
• Cell responses regulated by early reorganization of actin cytoskeleton

  2008cites this paper
• Inhibition of proliferation in colon cancer cell lines and harmful enzyme activity of colon bacteria by Bifidobacterium adolescentis SPM0212

  2008cites this paper
• Anti-proliferative effects of Bifidobacterium adolescentis SPM0212 extract on human colon cancer cell lines

  2008cites this paper
• Modeling gene-by-environment interaction in comorbid depression with alcohol use disorders via an integrated bioinformatics approach

  2008influential citation
• In vivo preconditioning with normobaric hyperoxia induces ischemic tolerance partly by triggering tumor necrosis factor-alpha converting enzyme/tumor necrosis factor-alpha/nuclear factor-kappaB.

  2008cites this paper
• Intramolecular interactions of MARCKS and its relationship to tumor necrosis factor -alpha and rheumatoid arthritis

  2008cites this paper
• TNF-α Induces Apoptosis Through JNK/Bax-Dependent Pathway in Differentiated, but not Naïve PC12 Cells

  2007cites this paper
• ceramide and pathophysiological aspects of

  2007cites this paper
• Ceramide: physiological and pathophysiological aspects.

  2007cites this paper
• Acid Sphingomyelinase and Its Redox Amplification in Formation of Lipid Raft Redox Signaling Platforms in Endothelial Cells

  2007cites this paper
• Dysregulated growth factor gene expression is associated with tubulointerstitial apoptosis and renal dysfunction.

  2007cites this paper
• Tumor Necrosis Factor-α–Induced Apoptosis in Murine Cytomegalovirus Retinitis

  2007cites this paper
• Dendritic Cell and Macrophage-Mediated Tolerance in Lupus-Prone Mice

  2007cites this paper
• Tumor necrosis factor-alpha-induced apoptosis in murine cytomegalovirus retinitis.

  2007cites this paper
• Differential effects of TNfα on satellite cell differentiation

  2007cites this paper
• Physiological and pathophysiological aspects of ceramide.

  2006cites this paper
• Autocrine Growth Factor Signaling in Motility

  2006cites this paper
• The Functional Role of Actin Cytoskeleton Dynamics and Signaling

  2006cites this paper
• Septic cardiomyopathy - A not yet discovered cardiomyopathy?

  2006cites this paper
• Cell Motility in Cancer Invasion and Metastasis

  2006cites this paper
• Effect of tumor necrosis factor alpha and infliximab on apoptosis of B lymphocytes infected or not with Epstein-Barr virus.

  2006cites this paper
• Functional link between TNF biosynthesis and CaM-dependent activation of inducible nitric oxide synthase in RAW 264.7 macrophages.

  2006cites this paper
• Lipid rafts take center stage in endothelial cell redox signaling by death receptors.

  2006cites this paper
• Lipid Raft Clustering and Redox Signaling Platform Formation in Coronary Arterial Endothelial Cells

  2006cites this paper
• Apoptosis and oncosis in acute coronary syndromes: Assessment and implications

  2005cites this paper
• Activation of vascular smooth muscle cells by TNF and PDGF: overlapping and complementary signal transduction mechanisms.

  2005cites this paper
• Caveolae Signaling Complex Components into Ceramide-Enriched Clustering of DR 5 and Concentrating Death-Inducing Carcinoma Cells to TRAIL-Induced Apoptosis through Cyclooxygenase-2 Inhibition Sensitizes Human Colon

  2005cites this paper
• Role of tumour necrosis factor-alpha and other cytokines in ischemia-reperfusion-induced injury in the heart.

  2005cites this paper
• Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae.

  2005cites this paper
• Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors.

  2005cites this paper
• Surface Calreticulin Mediates Muramyl Dipeptide-induced Apoptosis in RK13 Cells*

  2005cites this paper
• Sequencing, chromosomal mapping, and functional characterization of bovine FLICE-Like Inhibitory Protein (FLIP)

  2005cites this paper
• β-Amyloid-Stimulated Microglia Induce Neuron Death via Synergistic Stimulation of Tumor Necrosis Factor α and NMDA Receptors

  2005cites this paper
• Vein Graft Neointimal Hyperplasia Is Exacerbated by Tumor Necrosis Factor Receptor-1 Signaling in Graft-Intrinsic Cells

  2004cites this paper
• Disabling of Receptor Activator of Nuclear Factor-κB (RANK) Receptor Complex by Novel Osteoprotegerin-like Peptidomimetics Restores Bone Loss in Vivo*

  2004cites this paper
• TNF-α-Induced Apoptosis of Macrophages Following Inhibition of NF-κB: A Central Role for Disruption of Mitochondria1

  2004cites this paper
• Effects of culture with TNF-α, TGF-β and insulin on sulphotransferase (SULT 1A1 and 1A3) activity in human colon and neuronal cell lines

  2004cites this paper
• Tumor necrosis factor-alpha promotes survival of opossum kidney cells via Cdc42-induced phospholipase C-gamma1 activation and actin filament redistribution.

  2004cites this paper
• Effects of culture with TNF-alpha, TGF-beta and insulin on sulphotransferase (SULT 1A1 and 1A3) activity in human colon and neuronal cell lines.

  2004cites this paper
• Endogenous Oxidative Stress Induces Distinct Redox Forms of Tumor Necrosis Factor Receptor‐1 in Melanoma Cells

  2004cites this paper
• Mechanism of liver cell injury by the cytostatic drug melphalan

  2004cites this paper
• TNF-alpha-induced apoptosis of macrophages following inhibition of NF-kappa B: a central role for disruption of mitochondria.

  2004cites this paper
• Deoxycholic Acid Activates the c-Jun N-terminal Kinase Pathway via FAS Receptor Activation in Primary Hepatocytes

  2004cites this paper
• T-CELL AND NEURONAL APOPTOSIS IN HIV INFECTION: IMPLICATIONS FOR THERAPEUTIC INTERVENTION

  2004cites this paper
• Induced Autocrine Signaling through the Epidermal Growth Factor Receptor Contributes to the Response of Mammary Epithelial Cells to Tumor Necrosis Factor α*

  2004cites this paper
• Tumor Necrosis Factor-α Promotes Survival of Opossum Kidney Cells via Cdc42-induced Phospholipase C-γ1 Activation and Actin Filament Redistribution

  2003cites this paper
• Neuroprotective effects of IGF-I against TNFalpha-induced neuronal damage in HIV-associated dementia.

  2003cites this paper
• Recruitment of TNF Receptor 1 to Lipid Rafts Is Essential for TNFα-Mediated NF-κB Activation

  2003cites this paper
• CellsEffects on the Activation and Apoptosis of T Induces Opposing and Time-Dependent Fibronectin-Associated Fas Ligand Rapidly

  2003cites this paper
• The inhibition of MAPK pathway is correlated with down-regulation of MMP-9 secretion induced by TNF-alpha in human keratinocytes.

  2003cites this paper
• Fibronectin-Associated Fas Ligand Rapidly Induces Opposing and Time-Dependent Effects on the Activation and Apoptosis of T Cells 1

  2003cites this paper
• Phosphorylation of NF-kappa B by calmodulin-dependent kinase IV activates anti-apoptotic gene expression.

  2003cites this paper
• Therapeutic vaccination with tumor cells that engage CD137

  2003cites this paper
• Endothelial activation by angiotensin II through NFκB and p38 pathways: Involvement of NFκB‐inducible kinase (NIK), free oxygen radicals, and selective inhibition by aspirin

  2003cites this paper
• Delayed Lymphocyte Apoptosis in Rheumatic Heart Disease

  2003cites this paper
• The transmembranous domain of CD40 determines CD40 partitioning into lipid rafts

  2003cites this paper
• Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation.

  2003cites this paper
• The effect of androgenic anabolic steroids on the susceptibility of the rat heart to ischaemia and reperfusion injury

  2002cites this paper
• Fatal shift of signal transduction is an integral part of neuronal differentiation: JNKs realize TNFalpha-mediated apoptosis in neuronlike, but not naive, PC12 cells.

  2002cites this paper
• Nitric Oxide-Induced Motility in Aortic Smooth Muscle Cells: Role of Protein Tyrosine Phosphatase SHP-2 and GTP-Binding Protein Rho

  2002cites this paper
• TACE/ADAM17–TNF-α Pathway in Rat Cortical Cultures after Exposure to Oxygen–Glucose Deprivation or Glutamate

  2002cites this paper