Nodal: master and commander of the dorsal-ventral and left-right axes in the sea urchin embryo.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Current Opinion in Genetics and Development

• Publication date

  2013-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.gde.2013.04.010PMID 23769944
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Diversification of oral and aboral mesodermal regulatory states in pregastrular sea urchin embryos.

  2013cited by this paper
• Gene regulatory control in the sea urchin aboral ectoderm: spatial initiation, signaling inputs, and cell fate lockdown.

  2013cited by this paper
• Opposing Nodal and BMP Signals Regulate Left–Right Asymmetry in the Sea Urchin Larva

  2012cited by this paper
• Direct and indirect control of oral ectoderm regulatory gene expression by Nodal signaling in the sea urchin embryo.

  2012cited by this paper
• Autonomy in specification of primordial germ cells and their passive translocation in the sea urchin

  2012cited by this paper
• Left-right patterning: conserved and divergent mechanisms

  2012cited by this paper
• Reciprocal Signaling between the Ectoderm and a Mesendodermal Left-Right Organizer Directs Left-Right Determination in the Sea Urchin Embryo

  2012cited by this paper
• Nodal‐mediated epigenesis requires dynamin‐mediated endocytosis

  2011cited by this paper
• The dynamic gene expression patterns of transcription factors constituting the sea urchin aboral ectoderm gene regulatory network

  2011cited by this paper
• Involvement of Delta and Nodal signals in the specification process of five types of secondary mesenchyme cells in embryo of the sea urchin, Hemicentrotus pulcherrimus

  2011cited by this paper
• Maternal Oct1/2 is required for Nodal and Vg1/Univin expression during dorsal-ventral axis specification in the sea urchin embryo.

  2011cited by this paper
• Oral-aboral patterning and gastrulation of sea urchin embryos depend on sulfated glycosaminoglycans.

  2011cited by this paper
• Ancestral Regulatory Circuits Governing Ectoderm Patterning Downstream of Nodal and BMP2/4 Revealed by Gene Regulatory Network Analysis in an Echinoderm

  2010cited by this paper
• TGFβ signaling positions the ciliary band and patterns neurons in the sea urchin embryo.

  2010cited by this paper
• Nodal and BMP2/4 pattern the mesoderm and endoderm during development of the sea urchin embryo

  2010cited by this paper
• Chordin is required for neural but not axial development in sea urchin embryos.

  2009cited by this paper
• Patterning of the Dorsal-Ventral Axis in Echinoderms: Insights into the Evolution of the BMP-Chordin Signaling Network

  2009cited by this paper
• A developmental perspective: changes in the position of the blastopore during bilaterian evolution.

  2009cited by this paper
• Oral-aboral axis specification in the sea urchin embryo III. Role of mitochondrial redox signaling via H2O2.

  2009cited by this paper
• Gene regulatory networks for ectoderm specification in sea urchin embryos.

  2009cited by this paper
• A perturbation model of the gene regulatory network for oral and aboral ectoderm specification in the sea urchin embryo.

  2009cited by this paper
• Network design principles from the sea urchin embryo.

  2009cited by this paper
• A Wnt-FoxQ2-nodal pathway links primary and secondary axis specification in sea urchin embryos.

  2008cited by this paper
• Evo-devo: variations on ancestral themes.

  2008cited by this paper
• A conserved role for the nodal signaling pathway in the establishment of dorso-ventral and left-right axes in deuterostomes.

  2008cited by this paper
• Lefty acts as an essential modulator of Nodal activity during sea urchin oral-aboral axis formation.

  2008cited by this paper
• Cis‐regulatory control of the nodal gene, initiator of the sea urchin oral ectoderm gene network

  2007cited by this paper
• Cis-regulatory analysis of nodal and maternal control of dorsal-ventral axis formation by Univin, a TGF-β related to Vg1

  2007cited by this paper
• Specification of ectoderm restricts the size of the animal plate and patterns neurogenesis in sea urchin embryos

  2006cited by this paper
• Repression of mesodermal fate by foxa, a key endoderm regulator of the sea urchin embryo

  2006cited by this paper
• Ion flow regulates left–right asymmetry in sea urchin development

  2006cited by this paper
• The C2H2 zinc finger genes of Strongylocentrotus purpuratus and their expression in embryonic development.

  2006cited by this paper
• Sea urchin Forkhead gene family: phylogeny and embryonic expression.

  2006cited by this paper
• Identification and characterization of homeobox transcription factor genes in Strongylocentrotus purpuratus, and their expression in embryonic development.

  2006cited by this paper
• p38 MAPK is essential for secondary axis specification and patterning in sea urchin embryos

  2006cited by this paper
• Left-right asymmetry in the sea urchin embryo is regulated by nodal signaling on the right side.

  2005cited by this paper
• Nodal and BMP2/4 signaling organizes the oral-aboral axis of the sea urchin embryo.

  2004cited by this paper
• SpHnf6, a transcription factor that executes multiple functions in sea urchin embryogenesis.

  2004cited by this paper
• On the origin of the chordate central nervous system: expression of onecut in the sea urchin embryo

  2004cited by this paper
• Nodal/activin signaling establishes oral–aboral polarity in the early sea urchin embryo

  2004cited by this paper
• LvTbx2/3: a T-box family transcription factor involved in formation of the oral/aboral axis of the sea urchin embryo

  2003cited by this paper
• Spdeadringer, a sea urchin embryo gene required separately in skeletogenic and oral ectoderm gene regulatory networks.

  2003cited by this paper
• Coquillette, a sea urchin T-box gene of the Tbx2 subfamily, is expressed asymmetrically along the oral-aboral axis of the embryo and is involved in skeletogenesis.

  2003cited by this paper
• New early zygotic regulators expressed in endomesoderm of sea urchin embryos discovered by differential array hybridization.

  2002cited by this paper
• Oral-aboral axis specification in the sea urchin embryo. I. Axis entrainment by respiratory asymmetry.

  2001cited by this paper
• Expression pattern of Brachyury in the embryo of the sea urchin Paracentrotus lividus

  2001cited by this paper
• Sea urchin goosecoid function links fate specification along the animal-vegetal and oral-aboral embryonic axes.

  2001cited by this paper
• Left-right positioning of the adult rudiment in sea urchin larvae is directed by the right side.

  2001cited by this paper
• The role of Brachyury (T) during gastrulation movements in the sea urchin Lytechinus variegatus.

  2001cited by this paper
• Oral-aboral axis specification in the sea urchin embryo II. Mitochondrial distribution and redox state contribute to establishing polarity in Strongylocentrotus purpuratus.

  2001cited by this paper
• A BMP pathway regulates cell fate allocation along the sea urchin animal-vegetal embryonic axis.

  2000cited by this paper
• A fate map of the vegetal plate of the sea urchin (Lytechinus variegatus) mesenchyme blastula.

  1996cited by this paper
• The fate of the small micromeres in sea urchin development.

  1986cited by this paper

• Emergence of a Central Nervous System: A Two-Step Evolutionary Model Suggested by Sea Urchin Experiments.

  2026cites this paper
• Nodal Signaling: A Paradigm for TGFβ Signaling in Embryonic Development.

  2025cites this paper
• Collagen processing is essential for germ cell identity

  2025cites this paper
• An RNA interference approach for functional studies in the sea urchin and its use in analysis of Nodal signaling gradients.

  2024cites this paper
• Expression and Transcriptional Targets of TGFβ‐RII in Paracentrotus lividus Larval Skeletogenesis

  2024cites this paper
• Contrasting the development of larval and adult body plans during the evolution of biphasic lifecycles in sea urchins

  2024cites this paper
• An RNA interference approach for functional studies in the sea urchin and its use in analysis of Nodal signaling gradients

  2024cites this paper
• Parentage influence on gene expression under acidification revealed through single‐embryo sequencing

  2023influential citation
• Gene Expression Analysis of the Stress Response to Lithium, Nickel, and Zinc in Paracentrotus lividus Embryos

  2022cites this paper
• Molecular Paleobiology of the Echinoderm Skeleton

  2022cites this paper
• Transformation of the Ancestral Body Plan and Axial Growth in Echinoderms: Ontogenetic and Paleontological Data

  2022cites this paper
• Plastic leachate-induced toxicity during sea urchin embryonic development: Insights into the molecular pathways affected by PVC.

  2022cites this paper
• Developmental atlas of the indirect-developing sea urchin Paracentrotus lividus: From fertilization to juvenile stages

  2022cites this paper
• Cadherins and the pathogenesis of epilepsy

  2022cites this paper
• Synthesis and antiproliferative properties of 3,4-diarylpyrrole-2-carboxamides

  2021cites this paper
• Transcriptomic analysis of Nodal - and BMP- associated genes during development to the juvenile seastar in Parvulastra exigua (Asterinidae).

  2021influential citation
• Two Benthic Diatoms, Nanofrustulum shiloi and Striatella unipunctata, Encapsulated in Alginate Beads, Influence the Reproductive Efficiency of Paracentrotus lividus by Modulating the Gene Expression

  2021cites this paper
• TGFβ family signaling and development

  2021cites this paper
• Maternal factors regulating symmetry breaking and dorsal-ventral axis formation in the sea urchin embryo.

  2020cites this paper
• Evolutionary Diversity of the Mechanisms Providing the Establishment of Left-Right Asymmetry in Metazoans

  2020cites this paper
• Deciphering and modelling the TGF-β signalling interplays specifying the dorsal-ventral axis of the sea urchin embryo

  2020cites this paper
• Molecular and cellular basis of left–right asymmetry in vertebrates

  2020cites this paper
• Genomic insights of body plan transitions from bilateral to pentameral symmetry in Echinoderms

  2020cites this paper
• Maternal control of early patterning in sea urchin embryos.

  2020cites this paper
• Expression of exogenous mRNAs to study gene function in echinoderm embryos.

  2019cites this paper
• Interplay between Lefty and Nodal signaling is essential for the organizer and axial formation in amphioxus embryos.

  2019cites this paper
• MAPK and GSK3/ß-TRCP-mediated degradation of the maternal Ets domain transcriptional repressor Yan/Tel controls the spatial expression of nodal in the sea urchin embryo

  2018cites this paper
• An organizing role for the TGF-β signaling pathway in axes formation of the annelid Capitella teleta.

  2018cites this paper
• Spatial and temporal control of NODAL signaling.

  2018cites this paper
• Effects of Nodal inhibition on development of temnopleurid sea urchins

  2018cites this paper
• Transforming growth factor‐β signal regulates gut bending in the sea urchin embryo

  2018cites this paper
• Canonical and non-canonical Wnt signaling pathways define the expression domains of Frizzled 5/8 and Frizzled 1/2/7 along the early anterior-posterior axis in sea urchin embryos.

  2018cites this paper
• Larval and Adult Body Axes in Echinoderms

  2018cites this paper
• The BMP2 nuclear variant, nBMP2, is expressed in mouse hippocampus and impacts memory

  2017cites this paper
• Early development of amphioxus links evolutionary events with vertebrates.

  2017cites this paper
• p38 MAPK as an essential regulator of dorsal-ventral axis specification and skeletogenesis during sea urchin development: a re-evaluation

  2017cites this paper
• The Sea Urchin Embryo: A Model for Studying Molecular Mechanisms Involved in Human Diseases and for Testing Bioactive Compounds

  2017cites this paper
• Funktionelle Analyse der Histondeacetylase 6 sowie experimentelle Modellierung von Lateralitätsdefekten während der Links-Rechts-Achsenentwicklung von Xenopus laevis und Paracentrotus lividus

  2017cites this paper
• Deep Homology?: Uncanny Similarities of Humans and Flies Uncovered by Evo-Devo

  2017cites this paper
• From so simple a beginning - what amphioxus can teach us about placode evolution.

  2017cites this paper
• Nodal and BMP expression during the transition to pentamery in the sea urchin Heliocidaris erythrogramma: insights into patterning the enigmatic echinoderm body plan

  2017influential citation
• Echinoderm development and evolution in the post-genomic era.

  2017cites this paper
• TGF-β sensu stricto signaling regulates skeletal morphogenesis in the sea urchin embryo.

  2017cites this paper
• The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions.

  2017cites this paper
• Acquisition of the dorsal structures in chordate amphioxus

  2016cites this paper
• Divergence of ectodermal and mesodermal gene regulatory network linkages in early development of sea urchins

  2016cites this paper
• Quantitative developmental transcriptomes of the Mediterranean sea urchin Paracentrotus lividus.

  2016cites this paper
• Contribution of hedgehog signaling to the establishment of left-right asymmetry in the sea urchin.

  2016cites this paper
• Divergence of gene regulatory network linkages during specification of ectoderm and 3 mesoderm in early development of sea urchins 4 5 Short Title : Divergence of GRNs in early echinoid embryos 6 7 Author Affiliations : 8

  2016cites this paper
• Evolution of gene regulatory network topology and dorsal-ventral axis specification in early development of sea urchins (Echinoidea)

  2016cites this paper
• Signal-Dependent Regulation of Skeletogenesis in the Sea Urchin Embryo

  2016cites this paper
• Evolution of Developmental Gene Regulatory Networks in Echinoids

  2016cites this paper
• Cilia are required for asymmetric nodal induction in the sea urchin embryo

  2016cites this paper
• Amphioxus mouth after dorso-ventral inversion

  2016cites this paper
• Divergence of gene regulatory network linkages during specification of ectoderm and mesoderm in early development of sea urchins

  2016cites this paper
• Symmetry Breaking and Establishment of Dorsal/Ventral Polarity in the Early Sea Urchin Embryo

  2015cites this paper
• A deuterostome origin of the Spemann organiser suggested by Nodal and ADMPs functions in Echinoderms

  2015cites this paper
• Transcriptomic analysis of Nodal- and BMP-associated genes during juvenile development of the sea urchin Heliocidaris erythrogramma.

  2015influential citation
• Evolution of basal deuterostome nervous systems

  2015cites this paper
• The Maternal Maverick/GDF15-like TGF-β Ligand Panda Directs Dorsal-Ventral Axis Formation by Restricting Nodal Expression in the Sea Urchin Embryo

  2015cites this paper
• The Nodal signaling pathway controls left-right asymmetric development in amphioxus

  2015cites this paper
• Ectopic hbox12 Expression Evoked by Histone Deacetylase Inhibition Disrupts Axial Specification of the Sea Urchin Embryo

  2015influential citation
• Diversity and convergence in the mechanisms establishing L/R asymmetry in metazoa

  2014cites this paper
• Symmetry breakage in the frog Xenopus: Role of Rab11 and the ventral‐right blastomere

  2014cites this paper
• Echinoderm conundrums: Hox genes, heterochrony, and an excess of mouths

  2014cites this paper
• Telling left from right: Left‐right asymmetric controls in sea urchins

  2014cites this paper
• Developmental gene regulatory network evolution: Insights from comparative studies in echinoderms

  2014cites this paper
• The evolution and conservation of left-right patterning mechanisms

  2014influential citation
• Specification and positioning of the anterior neuroectoderm in deuterostome embryos

  2014cites this paper
• Signal-dependent regulation of the sea urchin skeletogenic gene regulatory network.

  2014cites this paper
• Symmetry breakage in the vertebrate embryo: when does it happen and how does it work?

  2014cites this paper
• Early asymmetric cues triggering the dorsal/ventral gene regulatory network of the sea urchin embryo

  2014cites this paper
• Cellular Physiology and Biochemistry Cellular Physiology and Biochemistry Expression of Nodal on Bronchial Epithelial Cells Influenced by Lung Microbes through Dna Methylation Modulates the Differentiation of T-helper Cells

  year unknowncites this paper