Are Weight Status and Cognition Associated? An Examination of Cognitive Development in Children and Adolescents with Anorexia Nervosa 1 Year after First Hospitalisation

Abstract Objective The aim of this study was to characterise the association between the cognitive profile and weight restoration in children and adolescents with anorexia nervosa. Methods The study was a longitudinal, matched case–control, multicentre study. An assessment of cognitive functions was conducted by using the Wechsler Intelligence Scale for Children–III/the Wechsler Adult Intelligence Scale–III, the Test of Memory and Learning–second edition, Trail Making Tests A and B, the Rey–Osterrieth Complex Figure Test and the Cambridge Neuropsychological Test Automated Battery. Results One hundred twenty individuals, 60 patients with anorexia nervosa with mean age of 14.65 (SD 1.820) years and 60 healthy controls with mean age of 14.76 (SD 1.704) years, participated. No association was found between weight recovery and cognitive functions. However, a significant increase in motor speed was found in Trail Making Test A (p = 0.004), Reaction Time (RTI) five‐choice movement time (p = 0.002) and RTI simple movement time (p = 0.011), resulting in a normalisation corresponding to that found in healthy controls. Furthermore, a significantly lower score in the perceptual organization index (p = 0.029) was found at follow‐up. Conclusions Weight recovery appears not to be associated with cognition. Copyright © 2016 The Authors European Eating Disorders Review published by Eating Disorders Association and John Wiley & Sons Ltd

• Publication year

  2016

• Venue

  European eating disorders review

• Publication date

  2016-04-08

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1002/erv.2445PMID 27062554PMCID 5071769
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Prognostic factors and outcome in anorexia nervosa: a follow-up study

  2016cited by this paper
• Are Weight Status and Cognition Associated? An Examination of Cognitive Development in Children and Adolescents with Anorexia Nervosa 1 Year after First Hospitalisation

  2016cited by this paper
• Abilities : Their Structure , Growth , and Action

  2015cited by this paper
• Are There Differences in Central Coherence and Set Shifting Across the Subtypes of Anorexia Nervosa?: A Systematic Review

  2015cited by this paper
• Do Children and Adolescents with Anorexia Nervosa Display an Inefficient Cognitive Processing Style?

  2015cited by this paper
• Serum brain-derived neurotrophic factor and cognitive functioning in underweight, weight-recovered and partially weight-recovered females with anorexia nervosa.

  2014cited by this paper
• A Systematic Review of Central Coherence in Young People with AnorexiaNervosa

  2014cited by this paper
• Longitudinal examination of decision-making performance in anorexia nervosa: before and after weight restoration.

  2014cited by this paper
• Central coherence in eating disorders: An updated systematic review and meta-analysis

  2014cited by this paper
• Set shifting in children and adolescents with anorexia nervosa: an exploratory systematic review and meta-analysis.

  2014cited by this paper
• Central Coherence, Organizational Strategy, and Visuospatial Memory in Children and Adolescents With Anorexia Nervosa

  2014cited by this paper
• Cognitive remediation in anorexia nervosa and related conditions: a systematic review.

  2014cited by this paper
• Cognitive Profile of Children and Adolescents with Anorexia Nervosa

  2014influential reference
• Neuropsychological functioning in children and adolescents with restrictive-type anorexia nervosa: An in-depth investigation with NEPSY–II

  2013cited by this paper
• Diagnostic and Statistical Manual of Mental Disorders

  2013cited by this paper
• An examination of the ravello profile--a neuropsychological test battery for anorexia nervosa.

  2012cited by this paper
• Severe anorexia nervosa in men: comparison with severe AN in women and analysis of mortality.

  2012influential reference
• Extended international (IOTF) body mass index cut‐offs for thinness, overweight and obesity

  2012influential reference
• Cognitive flexibility in juvenile anorexia nervosa patients before and after weight recovery

  2012influential reference
• Poor Cognitive Flexibility in Eating Disorders: Examining the Evidence using the Wisconsin Card Sorting Task

  2012cited by this paper
• Clinical and biological correlates of adolescent anorexia nervosa with impaired cognitive profile

  2011cited by this paper
• Critical appraisal of the provisional DSM-5 criteria for anorexia nervosa and an alternative proposal.

  2011cited by this paper
• Association between neuroendocrinological parameters and learning and memory functions in adolescent anorexia nervosa before and after weight recovery

  2011influential reference
• Cognitive flexibility and Agouti-related protein in adolescent patients with anorexia nervosa.

  2011influential reference
• Cognitive Flexibility and Clinical Severity in Eating Disorders

  2011influential reference
• Screening Questionnaire

  2010cited by this paper
• Epidemiology of Anorexia Nervosa in Men: A Nationwide Study of Finnish Twins

  2009influential reference
• Excess mortality, causes of death and prognostic factors in anorexia nervosa

  2009cited by this paper
• In first presentation adolescent anorexia nervosa, do cognitive markers of underweight status change with weight gain following a refeeding intervention?

  2009influential reference
• [Early risk factors of eating disorders--do events of prenatal and perinatal periods bear significance?].

  2009cited by this paper
• Test of Memory and Learning

  2008cited by this paper
• Implications of starvation-induced change in right dorsal anterior cingulate volume in anorexia nervosa.

  2008influential reference
• Metacognition in anorexia nervosa, dieting and non-dieting controls: a preliminary investigation.

  2007cited by this paper
• The prevalence and correlates of eating disorders in the National Comorbidity Survey Replication.

  2007cited by this paper
• Neuropsychological assessment

  2007cited by this paper
• Prevalence, heritability, and prospective risk factors for anorexia nervosa.

  2006influential reference
• Decision-making functioning as a predictor of treatment outcome in anorexia nervosa.

  2006cited by this paper
• Medical complications of anorexia nervosa and bulimia nervosa

  2006cited by this paper
• Is impaired set-shifting an endophenotype of anorexia nervosa?

  2005cited by this paper
• Cognitive flexibility in anorexia nervosa and bulimia nervosa

  2004cited by this paper
• Scoring Reliability on the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III)

  2003cited by this paper
• Cognitive impairment in anorexia nervosa is not due to depressed mood.

  2003cited by this paper
• Neuropsychological Characteristics of Patients in a Hospital-Based Eating Disorder Program

  2002influential reference
• Comparisons of men with full or partial eating disorders, men without eating disorders, and women with eating disorders in the community.

  2001influential reference
• K-SADS-PL.

  2000cited by this paper
• Using the eating disorder examination to identify the specific psychopathology of binge eating disorder.

  2000cited by this paper
• Essentials of WISC-IV Assessment

  2000cited by this paper
• A Screening Questionnaire for Asperger Syndrome and Other High-Functioning Autism Spectrum Disorders in School Age Children

  1999cited by this paper
• Test\re-test reliability of the CANTAB and ISPOCD neuropsychological batteries: theoretical and practical issues

  1998influential reference
• Test/re-test reliability of the CANTAB and ISPOCD neuropsychological batteries: theoretical and practical issues. Cambridge Neuropsychological Test Automated Battery. International Study of Post-Operative Cognitive Dysfunction.

  1998cited by this paper
• The Strengths and Difficulties Questionnaire: a research note.

  1997cited by this paper
• The cognitive profile of anorexia nervosa: a comparative study including a community-based sample.

  1996cited by this paper
• Body image, body dysphoria, and dietary restraint: factor structure in nonclinical subjects.

  1995cited by this paper
• Medical complications of anorexia nervosa and bulimia nervosa.

  1990cited by this paper
• The Validity of the Eating Disorder Examination and its Subscales

  1989cited by this paper
• The Halstead-Reitan Neuropsychological Test Battery: Theory and Clinical Interpretation.

  1986cited by this paper
• Manual for the Wechsler intelligence scale for children

  1974influential reference
• Eating Disorders: Obesity, Anorexia Nervosa, and the Person Within

  1973cited by this paper
• Psychological testing.

  1960influential reference

• Prospective associations among nonverbal reasoning abilities, illness duration, and eating disorder symptoms in anorexia nervosa and bulimia nervosa

  2026cites this paper
• Does cognitive functioning improve with weight restoration? An examination of changes in intelligence quotient scores in adolescents with anorexia nervosa before and after treatment.

  2025cites this paper
• A systematic review on executive functions in female adolescents with eating disorders: Implications on daily life and relevance to rehabilitation

  2025cites this paper
• The Influence of Negative Affect on Working Memory Updating of Food Stimuli Among Adolescents With Anorexia Nervosa

  2025cites this paper
• Severe and Enduring Anorexia Nervosa and Quality of Life: If, When, and How Palliative Care Should be Involved in Patient Care.

  2025cites this paper
• Differential neural responses to body image-related cyberbullying in adolescent females

  2025cites this paper
• Group cognitive remediation therapy for adolescents with anorexia nervosa: Outcomes before, after, and during follow-up in a real-world setting in Japan

  2024cites this paper
• Cognitive performance in hospitalized patients with severe or extreme anorexia nervosa

  2023cites this paper
• Phonological working memory is adversely affected in adults with anorexia nervosa: a systematic literature review

  2022cites this paper
• Catch‐up fat in male adults induces low testosterone and consequently promotes metabolic abnormalities and cognitive impairment

  2022cites this paper
• The shifting perspectives study protocol: Cognitive remediation therapy as an adjunctive treatment to family based treatment for adolescents with anorexia nervosa.

  2021cites this paper
• Cognitive improvement following weight gain in patients with anorexia nervosa: A systematic review.

  2020cites this paper
• Sweetened Condensed Consumption of More Than 1 Glass Per Day Has an Impact on Underweight Among Children Under Age Five

  2020cites this paper
• Case report: cognitive performance in an extreme case of anorexia nervosa with a body mass index of 7.7

  2020cites this paper
• Evaluation of cognitive function in patients with severe anorexia nervosa before and after medical stabilization

  2020cites this paper
• Cognitive flexibility in acute anorexia nervosa and after recovery: A systematic review.

  2020cites this paper
• Attention allocation to illness-compatible information discriminates women with active versus weight-recovered anorexia nervosa.

  2019cites this paper
• General and Eating Disorder Specific Flexibility: Development and Validation of the Eating Disorder Flexibility Index (EDFLIX) Questionnaire

  2019cites this paper
• Decision‐making impairment in anorexia nervosa: New insights into the role of age and decision‐making style

  2018cites this paper
• An Overview of Conceptualizations of Eating Disorder Recovery, Recent Findings, and Future Directions

  2018cites this paper
• Cognitive remediation therapy for adolescent inpatients with severe and complex anorexia nervosa: A treatment trial

  2018cites this paper
• Neurocognitive functions and social functioning in young females with recent-onset anorexia nervosa and recovered individuals

  2017cites this paper
• Are Weight Status and Cognition Associated? An Examination of Cognitive Development in Children and Adolescents with Anorexia Nervosa 1 Year after First Hospitalisation

  2016cites this paper
• Do Children and Adolescents with Anorexia Nervosa Display an Inefficient Cognitive Processing Style?

  2015cites this paper