Maintenance of murine oocyte meiotic arrest: uptake and metabolism of hypoxanthine and adenosine by cumulus cell-enclosed and denuded oocytes.

No abstract is available for this paper.

• Publication year

  1986

• Venue

  Developmental Biology

• Publication date

  1986-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0012-1606(86)90359-3PMID 2875006
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Hypoxanthine and adenosine in murine ovarian follicular fluid: concentrations and activity in maintaining oocyte meiotic arrest.

  1985cited by this paper
• Hypoxanthine is the principal inhibitor of murine oocyte maturation in a low molecular weight fraction of porcine follicular fluid.

  1985cited by this paper
• Metabolic, fluorescent dye and electrical coupling between hamster oocytes and cumulus cells during meiotic maturation in vivo and in vitro.

  1985cited by this paper
• Cyclic adenosine monophosphate and ovarian follicular fluid act synergistically to inhibit mouse oocyte maturation.

  1984cited by this paper
• Adenosine amplifies follicle-stimulating hormone action in granulosa cells and luteinizing hormone action in luteal cells of rat and human ovaries.

  1983cited by this paper
• Inhibition of soluble 5'-nucleotidase from rat brain by different xanthine derivatives.

  1983cited by this paper
• The relationship between cumulus cell-oocyte coupling, oocyte meiotic maturation, and cumulus expansion.

  1982cited by this paper
• Purine amplification of luteinizing hormone action in ovarian luteal cells.

  1981cited by this paper
• Biochemical studies of mammalian oogenesis: metabolic cooperativity between granulosa cells and growing mouse oocytes.

  1981cited by this paper
• Ribonucleoside metabolism by mouse oocytes: metabolic cooperativity between the fully grown oocyte and cumulus cells.

  1980cited by this paper
• Measurement of intercellular coupling between oocytes and cumulus cells using intracellular markers.

  1980cited by this paper
• Cell-to-cell communication and ovulation. A study of the cumulus-oocyte complex

  1978cited by this paper
• Inhibition of maturation and metabolism in rat oocytes by cyclic amp.

  1977cited by this paper
• Gap junctions between the oocyte and companion follicle cells in the mammalian ovary

  1976cited by this paper
• Meiotic maturation of mouse oocytes in vitro: inhibition of maturation at specific stages of nuclear progression.

  1976cited by this paper
• Organization of intramembrane particles in freeze-cleaved gap junctions of rat graafian rollicles: optical-diffraction analysis.

  1976cited by this paper
• Hamster oocyte maturation in vitro: inhibition by follicular components.

  1976cited by this paper
• An inhibitory influence of granulosa cells and follicular fluid upon porcine oocyte meiosis in vitro.

  1975cited by this paper
• Action of bredinin on mammalian cells.

  1975cited by this paper
• The inhibition of nucleic acid synthesis by mycophenolic acid.

  1969cited by this paper
• The maturation of rabbit oocytes in culture and their maturation, activation, fertilization and subsequent development in the Fallopian tubes†

  1955cited by this paper

• The dominant follicle: the final frontier in bovine oocyte development

  2025cites this paper
• The Simulated Physiological Oocyte Maturation (SPOM) System Enhances Cytoplasmic Maturation and Oocyte Competence in Cattle

  2024cites this paper
• Characterization of metabolic patterns in porcine cumulus cells during meiotic maturation.

  2024cites this paper
• Biochemical alterations in the follicular fluid of bovine peri-ovulatory follicles and their association with final oocyte maturation

  2022cites this paper
• Metabolic control of oocyte development

  2022cites this paper
• Coordinated Formation of IMPDH2 Cytoophidium in Mouse Oocytes and Granulosa Cells

  2021cites this paper
• Characterization of Metabolic Patterns in Mouse Oocytes during Meiotic Maturation.

  2020cites this paper
• Dynamic genome-scale cell-specific metabolic models reveal novel inter-cellular and intra-cellular metabolic communications during ovarian follicle development

  2019cites this paper
• The art of oocyte meiotic arrest regulation

  2019cites this paper
• Nppc/Npr2/cGMP signaling cascade maintains oocyte developmental capacity.

  2019cites this paper
• Purinergic Signaling: A New Regulator of Ovarian Function

  2018cites this paper
• Production of Energy and Determination of Competence: Past Knowledge, Present Research, and Future Opportunities in Oocyte and Embryo Metabolism

  2017cites this paper
• Roles of epidermal growth factor (EGF)-like factor in the ovulation process

  2016cites this paper
• Role of maternal SIN3A in reprogramming gene expression during mouse preimplantation development

  2016cites this paper
• Maternal SIN 3 A Regulates Reprogramming of Gene Expression During Mouse Preimplantation Development 1

  2016cites this paper
• Maternal SIN3A Regulates Reprogramming of Gene Expression During Mouse Preimplantation Development1

  2015cites this paper
• Purinergic signaling in the ovary

  2015cites this paper
• ADENOSINE AND OVARIAN FUNCTION Studies on adenosine as substrate and receptor agonist in the rat ovary

  2014cites this paper
• Metabolic control of oocyte development: linking maternal nutrition and reproductive outcomes

  2014cites this paper
• Bidirectional communication between oocytes and ovarian follicular somatic cells is required for meiotic arrest of mammalian oocytes

  2013influential citation
• Regulation of Oocyte Meiotic Resumption by Somatic Cells

  2013cites this paper
• Oocyte Metabolism and Its Relationship to Developmental Competence

  2013cites this paper
• Regulation of oocyte meiotic maturation by somatic cells

  2012cites this paper
• Comparative proteomic analysis of proteins involved in oocyte meiotic maturation in mice

  2012cites this paper
• Estradiol promotes and maintains cumulus cell expression of natriuretic peptide receptor 2 (NPR2) and meiotic arrest in mouse oocytes in vitro.

  2011cites this paper
• Mouse versus rat: Profound differences in meiotic regulation at the level of the isolated oocyte

  2011cites this paper
• Cumulus Cells are an Essential Mediator of Ovulation Stimuli from Granulosa Cells to Oocyte

  2010cites this paper
• Regulation of the G2/M transition in rodent oocytes

  2010cites this paper
• Effects of cattle oocyte quality on pronuclear formation and subsequent embryo development

  2009cites this paper
• Effect of LH on nuclear and cytoplasm synchronization for in vitro maturation of ovine oocytes.

  2009cites this paper
• Factors affecting the developmental competence of pig oocytes matured in vitro.

  2007cites this paper
• Metabolism, protein content, and in vitro embryonic development of goat cumulus–oocyte complexes matured with physiological concentrations of glucose and L‐lactate

  2006cites this paper
• Chapter 3 Interaction of oocyte and somatic cells

  2006cites this paper
• Differential response of cumulus cell‐enclosed and denuded mouse oocytes in a meiotic induction model system

  2006cites this paper
• Clinical use of pentoxifylline for activation of immotile testicular sperm before ICSI in patients with azoospermia.

  2006cites this paper
• The Biological Basis of Oocyte and Embryo Competence: Morphodynamic Criteria for Embryo Selection in In-Vitro Fertilization

  2004cites this paper
• Stimulation of Parthenogenesis in Mouse Ovarian Follicles by Inhibitors of Inosine Monophosphate Dehydrogenase’

  2004cites this paper
• Phosphatidylinositol 3-kinase in cumulus cells is responsible for both suppression of spontaneous maturation and induction of gonadotropin-stimulated maturation of porcine oocytes.

  2003cites this paper
• Hypoxanthine (HX) inhibition of in vitro meiotic resumption in goat oocytes

  2003cites this paper
• Release of ATP induced by hypertonic solutions in Xenopus oocytes

  2003cites this paper
• A potential role for AMP-activated protein kinase in meiotic induction in mouse oocytes.

  2002cites this paper
• Minireview: Functions of the cumulus oophorus during oocyte maturation, ovulation, and fertilization

  2002cites this paper
• FSH and LH induce progesterone production and progesterone receptor synthesis in cumulus cells: a requirement for meiotic resumption in porcine oocytes.

  2002cites this paper
• The Future of the Oocyte

  2002cites this paper
• The biochemistry of oocyte maturation.

  2002cites this paper
• The meiotic arrest of bovine oocytes

  2002cites this paper
• Dynamic Changes of Connexin-43, Gap Junctional Protein, in Outer Layers of Cumulus Cells Are Regulated by PKC and PI 3-Kinase During Meiotic Resumption in Porcine Oocytes

  2001cites this paper
• Control of oocyte nuclear and cytoplasmic maturation.

  2001cites this paper
• Oocyte and Embryo Culture

  2000cites this paper
• Phosphorylation of Connexin-43, Gap Junctional Protein, in Cumulus Cells is Regulated by Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase during In Vitro Meiotic Resumption in Porcine Follicular Oocytes

  1999cites this paper
• Uptake and metabolism of adenosine mediate a meiosis‐arresting action on mouse oocytes

  1999cites this paper
• Precursors of the purine backbone augment the inhibitory action of hypoxanthine and dibutyryl cAMP on mouse oocyte maturation.

  1998cites this paper
• Involvement of purine nucleotide synthetic pathways in gonadotropin‐induced meiotic maturation in mouse cumulus cell‐enclosed oocytes

  1997cites this paper
• Hypoxanthine regulation of oocyte maturation in the mouse: insights using hypoxanthine phosphoribosyltransferase-deficient animals.

  1997cites this paper
• Role of the cyclic adenosine monophosphate-dependent protein kinase in the control of meiotic resumption in bovine oocytes cultured with thecal cell monolayers.

  1997cites this paper
• Human sperm motility-enhancing agents have detrimental effects on mouse oocytes and embryos.

  1995cites this paper
• Inhibitory action of hypoxanthine on meiotic resumption of denuded pig follicular oocytes in vitro.

  1995cites this paper
• The influence of glucose, cumulus cells, and metabolic coupling on ATP levels and meiotic control in the isolated mouse oocyte.

  1995cites this paper
• 8 – Molecular Mechanisms in Ovulation

  1994cites this paper
• Acquisition of meiotic competence by denuded mouse oocytes: participation of somatic-cell product(s) and cAMP.

  1994cites this paper
• The Ovarian Egg and Ovulation

  1994cites this paper
• High performance liquid chromatography analysis of hypoxanthine metabolism in mouse oocyte-cumulus cell complexes: effects of purine metabolic perturbants.

  1994cites this paper
• Follicular Control of Meiotic Maturation in Mammalian Oocytes

  1993cites this paper
• Acquisition of maturational competence in in vitro grown mouse oocytes.

  1993cites this paper
• Purine control of mouse oocyte maturation: Evidence that nonmetabolized hypoxanthine maintains meiotic arrest

  1993influential citation
• Cell cycle control during mammalian oogenesis.

  1993cites this paper
• Factors affecting the resumption of meiotic maturation in mammalian oocytes

  1993cites this paper
• Regulation of mammalian oocyte maturation.

  1993cites this paper
• Nonsteroidal signals originating in the gonads.

  1992cites this paper
• Inhibitory effect of purines in meiotic maturation of denuded mouse oocytes

  1992cites this paper
• Purine utilisation, de novo synthesis and degradation in mouse preimplantation embryos.

  1992cites this paper
• Modulation of meiotic arrest in mouse oocytes by guanyl nucleotides and modifiers of G-proteins.

  1992cites this paper
• Metabolic coupling and ligand-stimulated meiotic maturation in the mouse oocyte-cumulus cell complex.

  1991cites this paper
• Hypoxanthine-maintained two-cell block in mouse embryos: dependence on glucose and effect of hypoxanthine phosphoribosyltransferase inhibitors.

  1991cites this paper
• Purines inhibit the development of mouse embryos in vitro.

  1990cites this paper
• Hyaluronic acid synthesis and gap junction endocytosis are necessary for normal expansion of the cumulus mass

  1990cites this paper
• [The regulation of meiotic inhibition and reinitiation in mammalian oocytes].

  1990cites this paper
• Effects of glucose and adenosine on the ATP content of hamster spermatids.

  1990cites this paper
• Effects of follicle stimulating hormone and purines on rat oocyte maturation

  1990cites this paper
• Preendocytotic alterations in cumulus cell gap junctions precede meiotic resumption in the rat cumulus-oocyte complex.

  1990cites this paper
• Stimulation of parthenogenesis in mouse ovarian follicles by inhibitors of inosine monophosphate dehydrogenase.

  1990cites this paper
• 12 – The Molecular Biology of Mammalian Oocyte Maturation

  1989cites this paper
• Effects of progesterone and a progesterone antagonist (RU486) on germinal vesicle breakdown in the mouse

  1989cites this paper
• In vivo administration of allopurinol affects ovulation and early embryonic development in rabbits.

  1989cites this paper
• Timing of nuclear progression and protein synthesis necessary for meiotic maturation of bovine oocytes.

  1989cites this paper
• Intragonadal regulation of follicular maturation.

  1989cites this paper
• Meiotic resumption and gap junction modulation in the cultured rat cumulus-oocyte complex.

  1989cites this paper
• Maintenance of meiotic arrest in mouse oocytes by purines: modulation of cAMP levels and cAMP phosphodiesterase activity.

  1989cites this paper
• Gonadotropin-induced murine oocyte maturation in vivo is not associated with decreased cyclic adenosine monophosphate in the oocyte-cumulus cell complex.

  1988cites this paper
• In vitro inhibition of oocyte nuclear maturation in the bovine.

  1988cites this paper
• Regulation of the Meiotic Cycle in Oocytes of Domestic Mammals

  1988cites this paper
• Induction of maturation in cumulus cell-enclosed mouse oocytes by follicle-stimulating hormone and epidermal growth factor: evidence for a positive stimulus of somatic cell origin.

  1988cites this paper
• Adenosine potentiates forskolin-induced delay of meiotic resumption by mouse denuded oocytes: evidence for an oocyte surface site of adenosine action.

  1988cites this paper
• The endocrine environment of the human oocyte.

  1988cites this paper
• Hypoxanthine causes a 2-cell block in random-bred mouse embryos.

  1987cites this paper
• Mammalian oocyte maturation.

  1987cites this paper
• Factors Controlling Mammalian Oocyte Maturation

  1987cites this paper
• Induction of mouse oocyte maturation in vivo by perturbants of purine metabolism.

  1987cites this paper
• The effect of hypoxanthine on mouse oocyte growth and development in vitro: maintenance of meiotic arrest and gonadotropin-induced oocyte maturation.

  1987cites this paper
• Inhibition of mouse oocyte cyclic AMP phosphodiesterase by steroid hormones: a possible mechanism for steroid hormone inhibition of oocyte maturation.

  1987cites this paper