Induction of competence regulons as a general response to stress in gram-positive bacteria.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Annual Review of Microbiology

• Publication date

  2006-09-11

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1146/ANNUREV.MICRO.60.080805.142139PMID 16771651
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Inhibition of competence development in Streptococcus pneumoniae by increased basal-level expression of the ComDE two-component regulatory system.

  2006cited by this paper
• New insights into the pneumococcal fratricide: relationship to clumping and identification of a novel immunity factor

  2006cited by this paper
• Antibiotic Stress Induces Genetic Transformability in the Human Pathogen Streptococcus pneumoniae

  2006cited by this paper
• Conservation of genes and processes controlled by the quorum response in bacteria: characterization of genes controlled by the quorum‐sensing transcription factor ComA in Bacillus subtilis

  2005cited by this paper
• Differential Single-stranded DNA Binding Properties of the Paralogous SsbA and SsbB Proteins from Streptococcus pneumoniae*

  2005cited by this paper
• The Ins and Outs of DNA Transfer in Bacteria

  2005cited by this paper
• Stripping Bacillus: ComK auto‐stimulation is responsible for the bistable response in competence development

  2005cited by this paper
• Choline-Binding Protein D (CbpD) in Streptococcus pneumoniae Is Essential for Competence-Induced Cell Lysis

  2005cited by this paper
• Interplay between DNA replication and recombination in prokaryotes.

  2005cited by this paper
• The Rok Protein of Bacillus subtilis Represses Genes for Cell Surface and Extracellular Functions

  2005cited by this paper
• A novel CRP-dependent regulon controls expression of competence genes in Haemophilus influenzae.

  2005cited by this paper
• Genetic Composition of the Bacillus subtilis SOS System

  2005cited by this paper
• The selective advantage of microbial fratricide.

  2005cited by this paper
• Quorum sensing: cell-to-cell communication in bacteria.

  2005cited by this paper
• Two Distinct Functions of ComW in Stabilization and Activation of the Alternative Sigma Factor ComX in Streptococcus pneumoniae

  2005cited by this paper
• Bistability in the Bacillus subtilis K‐state (competence) system requires a positive feedback loop

  2005cited by this paper
• Competence-programmed predation of noncompetent cells in the human pathogen Streptococcus pneumoniae: genetic requirements.

  2005cited by this paper
• DNA polymerase I acts in translesion synthesis mediated by the Y‐polymerases in Bacillus subtilis

  2005cited by this paper
• Synergistic Regulation of Competence Development in Bacillus subtilis by Two Rap-Phr Systems

  2005cited by this paper
• The H2O2 Stress-Responsive Regulator PerR Positively Regulates srfA Expression in Bacillus subtilis

  2005cited by this paper
• Stress responses and genetic variation in bacteria.

  2005cited by this paper
• DNA uptake during bacterial transformation

  2004cited by this paper
• Identification of ComW as a new component in the regulation of genetic transformation in Streptococcus pneumoniae

  2004cited by this paper
• SOS Response Induction by ß-Lactams and Bacterial Defense Against Antibiotic Lethality

  2004cited by this paper
• Release of DNA into the medium by competent Streptococcus pneumoniae: kinetics, mechanism and stability of the liberated DNA

  2004cited by this paper
• Interconnection of competence, stress and CiaR regulons in Streptococcus pneumoniae: competence triggers stationary phase autolysis of ciaR mutant cells

  2004cited by this paper
• Identification of competence pheromone responsive genes in Streptococcus pneumoniae by use of DNA microarrays

  2004cited by this paper
• SOS response promotes horizontal dissemination of antibiotic resistance genes

  2004cited by this paper
• Distinctive genetic features exhibited by the Y‐family DNA polymerases in Bacillus subtilis

  2004cited by this paper
• The Streptococcus pneumoniae cia Regulon: CiaR Target Sites and Transcription Profile Analysis

  2003cited by this paper
• Controlling competence in Bacillus subtilis: shared use of regulators.

  2003cited by this paper
• Competence-Induced Cells of Streptococcuspneumoniae Lyse Competence-Deficient Cells of the SameStrain duringCocultivation

  2003cited by this paper
• TPR‐mediated interaction of RapC with ComA inhibits response regulator‐DNA binding for competence development in Bacillus subtilis

  2003cited by this paper
• Binding of response regulator DegU to the aprE promoter is inhibited by RapG, which is counteracted by extracellular PhrG in Bacillus subtilis

  2003cited by this paper
• Transformation of Streptococcus pneumoniae relies on DprA‐ and RecA‐dependent protection of incoming DNA single strands

  2003cited by this paper
• Bacterial "competence" genes: signatures of active transformation, or only remnants?

  2003cited by this paper
• Transient Association of an Alternative Sigma Factor, ComX, with RNA Polymerase during the Period of Competence for Genetic Transformation in Streptococcus pneumoniae

  2003cited by this paper
• Roles of YqjH and YqjW, Homologs of the Escherichiacoli UmuC/DinB or Y Superfamily of DNA Polymerases, in Stationary-Phase Mutagenesis and UV-Induced Mutagenesis of Bacillussubtilis

  2003cited by this paper
• The Bacillus subtilis transition state regulator AbrB binds to the -35 promoter region of comK.

  2003cited by this paper
• Molecular Analysis of Phr Peptide Processing in Bacillus subtilis

  2003cited by this paper
• A novel type of conserved DNA-binding domain in the transcriptional regulators of the AlgR/AgrA/LytR family.

  2002cited by this paper
• Whole-Genome Analysis of Genes Regulated by the Bacillus subtilis Competence Transcription Factor ComK

  2002cited by this paper
• Uptake of transforming DNA in Gram‐positive bacteria: a view from Streptococcus pneumoniae

  2002cited by this paper
• Microarray analysis of the Bacillus subtilis K‐state: genome‐wide expression changes dependent on ComK

  2002cited by this paper
• Characterization of comQ and comX, Two Genes Required for Production of ComX Pheromone in Bacillus subtilis

  2002cited by this paper
• Transformation and Recombination

  2002cited by this paper
• Rok (YkuW) regulates genetic competence in Bacillus subtilis by directly repressing comK

  2002cited by this paper
• Bacillus subtilis and Its Closest Relatives

  2002cited by this paper
• Microarray-Based Identification of htrA, a Streptococcus pneumoniae Gene That Is Regulated by the CiaRH Two-Component System and Contributes to Nasopharyngeal Colonization

  2002cited by this paper
• Specific activation of the Bacillus quorum‐sensing systems by isoprenylated pheromone variants

  2002cited by this paper
• Extracellular-peptide control of competence for genetic transformation in Streptococcus pneumoniae.

  2002cited by this paper
• Induction of natural competence in Streptococcus pneumoniae triggers lysis and DNA release from a subfraction of the cell population

  2002cited by this paper
• Improving the predictive value of the competence transcription factor (ComK) binding site in Bacillus subtilis using a genomic approach.

  2002cited by this paper
• Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein

  2002cited by this paper
• Do bacteria have sex?

  2001cited by this paper
• Control of a Family of Phosphatase Regulatory Genes (phr) by the Alternate Sigma Factor Sigma-H ofBacillus subtilis

  2001cited by this paper
• Sigma A recognition sites in the Bacillus subtilis genome.

  2001cited by this paper
• The Bacillus subtilis Competence Transcription Factor, ComK, Overrides LexA-imposed Transcriptional Inhibition without Physically Displacing LexA*

  2001cited by this paper
• Pentapeptide regulation of aspartyl-phosphate phosphatases.

  2001cited by this paper
• A ComGA‐dependent checkpoint limits growth during the escape from competence

  2001cited by this paper
• Bacillus subtilis CodY represses early-stationary-phase genes by sensing GTP levels.

  2001cited by this paper
• Bacillus Subtilis and Its Closest Relatives: From Genes to Cells

  2001cited by this paper
• Global analysis of transcription kinetics during competence development in Streptococcus pneumoniae using high density DNA arrays

  2000cited by this paper
• Two-component signal transduction.

  2000cited by this paper
• Differential Processing of Propeptide Inhibitors of Rap Phosphatases in Bacillus subtilis

  2000cited by this paper
• Acid‐ and multistress‐resistant mutants of Lactococcus lactis : identification of intracellular stress signals

  2000cited by this paper
• Cross‐regulation of competence pheromone production and export in the early control of transformation in Streptococcus pneumoniae

  2000cited by this paper
• The pleiotropic response regulator DegU functions as a priming protein in competence development in Bacillus subtilis.

  2000cited by this paper
• Gene Expression Analysis of the Streptococcus pneumoniae Competence Regulons by Use of DNA Microarrays

  2000cited by this paper
• Adaptation to the environment: Streptococcus pneumoniae, a paradigm for recombination‐mediated genetic plasticity?

  2000cited by this paper
• Is the Ami-AliA/B oligopeptide permease of Streptococcus pneumoniae involved in sensing environmental conditions?

  2000cited by this paper
• Negative regulation of bacterial heat shock genes

  1999cited by this paper
• CtsR, a novel regulator of stress and heat shock response, controls clp and molecular chaperone gene expression in Gram‐positive bacteria

  1999cited by this paper
• Cell-cell signaling in bacteria

  1999cited by this paper
• Domain organization and molecular characterization of 13 two-component systems identified by genome sequencing of Streptococcus pneumoniae.

  1999cited by this paper
• Genetic Diversity of the Streptococcal Competence (com) Gene Locus

  1999cited by this paper
• An Autoregulatory Circuit Affecting Peptide Signaling in Bacillus subtilis

  1999cited by this paper
• DNA uptake in bacteria.

  1999cited by this paper
• Identification of DNA binding sites for ComE, a key regulator of natural competence in Streptococcus pneumoniae

  1999cited by this paper
• Competence for transformation: a matter of taste.

  1999cited by this paper
• Identification of a New Regulator inStreptococcus pneumoniae Linking Quorum Sensing to Competence for Genetic Transformation

  1999cited by this paper
• An Operon That Confers UV Resistance by Evoking the SOS Mutagenic Response in Streptococcal Conjugative Transposon Tn5252

  1999cited by this paper
• Competence‐specific induction of recA is required for full recombination proficiency during transformation in Streptococcus pneumoniae

  1998cited by this paper
• Development of competence in Streptococcus pneumoniae: pheromone autoinduction and control of quorum sensing by the oligopeptide permease

  1998cited by this paper
• The competence transcription factor of Bacillus subtilis recognizes short A/T-rich sequences arranged in a unique, flexible pattern along the DNA helix.

  1998cited by this paper
• Competence in Bacillus subtilis is controlled by regulated proteolysis of a transcription factor

  1998cited by this paper
• The ins and outs of peptide signaling.

  1998cited by this paper
• Bacterial transcript imaging by hybridization of total RNA to oligonucleotide arrays

  1998cited by this paper
• Biochemical characterization of a molecular switch involving the heat shock protein ClpC, which controls the activity of ComK, the competence transcription factor of Bacillus subtilis.

  1997cited by this paper
• An exported peptide functions intracellularly to contribute to cell density signaling in B. subtilis.

  1997cited by this paper
• Streptococcal Competence for Genetic Transformation: Regulation by Peptide Pheromones

  1997cited by this paper
• Natural competence in the genus Streptococcus: evidence that streptococci can change pherotype by interspecies recombinational exchanges

  1997cited by this paper
• DNA gyrase, topoisomerase IV, and the 4-quinolones

  1997cited by this paper
• Ubiquitous Distribution of the Competence Related Genes comA and comC Among Isolates of Streptococcus pneumoniae

  1997cited by this paper
• The evolution of bacterial transformation: sex with poor relations.

  1997cited by this paper
• A peptide export-import control circuit modulating bacterial development regulates protein phosphatases of the phosphorelay.

  1997cited by this paper
• Stable DNA replication: interplay between DNA replication, homologous recombination, and transcription.

  1997cited by this paper
• The HtrA family of serine proteases

  1997cited by this paper
• Competence for genetic transformation in encapsulated strains of Streptococcus pneumoniae: two allelic variants of the peptide pheromone

  1996cited by this paper
• Identification of the streptococcal competence‐pheromone receptor

  1996cited by this paper

• Cell density and single-cell heterogeneity reveal distinct competence induction dynamics in the high-GC Gram-positive Micrococcus luteus

  2026cites this paper
• A Streptococcus mutans retrospective: from oral pathogen to bacterial paradigm

  2026cites this paper
• Dissecting the role of comS-independent srf expression on multicellular differentiation and competence development in Bacillus subtilis.

  2026cites this paper
• Population structure can reduce clonal interference when sexual reproduction and dispersal are synchronized

  2025cites this paper
• Identification of a novel bacteriophage attachment site into ffs, the 4.5S non-coding RNA component of the signal recognition particle

  2025cites this paper
• The global proteome of Streptococcus pneumoniae EF3030 under nutrient-defined in vitro conditions

  2025cites this paper
• ComK-induced cell death is reversed by upregulating the SigB or Spx pathway in Bacillus subtilis

  2025cites this paper
• Elucidating the Role of the Competence Regulon Quorum Sensing Circuitry in Streptococcus cristatus.

  2025cites this paper
• The Genetic Determinants of Extreme UV Radiation and Desiccation Tolerance in a Bacterium Recovered from the Stratosphere

  2025cites this paper
• The Quorum Sensing-Controlled Competence Regulon Drives H2O2 Production in Streptococcus gordonii.

  2025cites this paper
• Structure, Function, and Regulation of LytA: The N-Acetylmuramoyl-l-alanine Amidase Driving the “Suicidal Tendencies” of Streptococcus pneumoniae—A Review

  2025cites this paper
• Molecular mechanisms and applications of natural transformation in bacteria

  2025cites this paper
• Mechanisms of Osteoblast-Like Cells and Bacterial Responses to Copper in Titanium-Copper Alloys.

  2025cites this paper
• Changes in the Protein Composition of the Exiguobacterium sibiricum Membrane with Decreasing Temperature: A Proteomic Analysis

  2025cites this paper
• A tripartite protein complex promotes DNA transport during natural transformation in Firmicutes

  2025cites this paper
• Quantitative phosphoproteomic reveals that the induction of competence modulates protein phosphorylation in Streptococcus pneumonaie.

  2025cites this paper
• Pneumococcal competence is a populational health sensor driving multilevel heterogeneity in response to antibiotics

  2024cites this paper
• Non-Canonical Aspects of Antibiotics and Antibiotic Resistance

  2024cites this paper
• Competence Regulation in Streptococcus pneumoniae and the Competence-targeted Anti-pneumococcal Strategies.

  2024cites this paper
• Decoding Adenine DNA Methylation Effects in Streptococcus Mutans: Insights Into Self‐DNA Protection and Autoaggregation

  2024cites this paper
• Competence induction of homologous recombination genes protects pneumococcal cells from genotoxic stress

  2024cites this paper
• New components of the community-based DNA-repair mechanism in Sulfolobales

  2024cites this paper
• Unveiling the regulatory network controlling natural transformation in lactococci

  2024influential citation
• Natural transformation-specific DprA coordinate DNA double-strand break repair pathways in heavily irradiated D. radiodurans

  2024cites this paper
• Unveiling the critical role of overlooked consumer protist-bacteria interactions in antibiotic resistance gene dissemination in urban sewage systems.

  2024cites this paper
• Multitasking functions of bacterial extracellular DNA in biofilms

  2024cites this paper
• From isotopically labeled DNA to fluorescently labeled dynamic pili: building a mechanistic model of DNA transport to the cytoplasmic membrane

  2024cites this paper
• Horizontal gene transfer among host-associated microbes.

  2023cites this paper
• The complex regulation of competence in Staphylococcus aureus under microaerobic conditions

  2023cites this paper
• comCDE (Competence) Operon Is Regulated by CcpA in Streptococcus pneumoniae D39

  2023cites this paper
• Antibacterial-Resistant Pathogens Mechanisms of Transmission and Strategies for Prevention and Control

  2023cites this paper
• Fever-like temperature bursts promote competence development via an HtrA-dependent pathway in Streptococcus pneumoniae

  2023cites this paper
• The RecA-directed recombination pathway of natural transformation initiates at chromosomal replication forks in the pneumococcus

  2023cites this paper
• Airway proteolytic control of pneumococcal competence

  2023cites this paper
• The oxidative stress response of Streptococcus pneumoniae: its contribution to both extracellular and intracellular survival

  2023cites this paper
• Antibiotics: Precious Goods in Changing Times.

  2023cites this paper
• Biochemical Properties and Roles of DprA Protein in Bacterial Natural Transformation, Virulence, and Pilin Variation

  2023cites this paper
• One Earth: The Equilibrium between the Human and the Bacterial Worlds

  2023cites this paper
• Transcriptome Analysis of Streptococcus mutans Quorum Sensing-Mediated Persisters Reveals an Enrichment in Genes Related to Stress Defense Mechanisms

  2023cites this paper
• Natural transformation specific DprA coordinate DNA double strand break repair pathways in heavily irradiated D. radiodurans

  2023cites this paper
• The function of the gene loiP in transformation efficiency and outer membrane permeability change of Escherichia coli treated by Ca2+ ions.

  2023cites this paper
• Pseudomonas aeruginosa və digər bakteriyalarda biotəbəqənin yaranma mexanizmi və Quorum Sensing Sistemi.

  2023cites this paper
• Global transcriptional responses of pneumococcus to human blood components and cerebrospinal fluid

  2022cites this paper
• Cell‐to‐cell non‐conjugative plasmid transfer between Bacillus subtilis and lactic acid bacteria

  2022cites this paper
• Antidepressants promote the spread of extracellular antibiotic resistance genes via transformation

  2022cites this paper
• Microaerobic conditions and the complex regulation of natural competence in Staphylococcus aureus

  2022cites this paper
• Link Between Antibiotic Persistence and Antibiotic Resistance in Bacterial Pathogens

  2022cites this paper
• Natural Transformation in Gram-Positive Bacteria and Its Biotechnological Relevance to Lactic Acid Bacteria.

  2022cites this paper
• Attenuating the Streptococcus pneumoniae Competence Regulon Using Urea-Bridged Cyclic Dominant-Negative Competence-Stimulating Peptide Analogs.

  2022cites this paper
• Pneumolysin promotes host cell necroptosis and bacterial competence during pneumococcal meningitis as shown by whole-animal dual RNA-seq

  2022cites this paper
• HopE and HopD Porin-Mediated Drug Influx Contributes to Intrinsic Antimicrobial Susceptibility and Inhibits Streptomycin Resistance Acquisition by Natural Transformation in Helicobacter pylori

  2022cites this paper
• A DNA-Damage Inducible Gene Promotes the Formation of Antibiotic Persisters in Response to the Quorum Sensing Signaling Peptide in Streptococcus mutans

  2022cites this paper
• Moonlighting proteins activate transformation in multidrug-resistant Streptococcus 1 pneumoniae epigenetic phase variants

  2022cites this paper
• The Impact of Natural Transformation on the Acquisition of Antibiotic Resistance Determinants

  2022cites this paper
• Antibiotic Discovery and Resistance: The Chase and the Race

  2022cites this paper
• Identification of New Chromosomal Loci Involved in com Genes Expression and Natural Transformation in the Actinobacterial Model Organism Micrococcus luteus

  2021cites this paper
• The Facts and Family Secrets of Plasmids That Replicate via the Rolling-Circle Mechanism

  2021cites this paper
• Simulated Microgravity Promotes Horizontal Gene Transfer of Antimicrobial Resistance Genes between Bacterial Genera in the Absence of Antibiotic Selective Pressure

  2021cites this paper
• CrfP, a fratricide protein, contributes to natural transformation in Streptococcussuis

  2021influential citation
• Update on the Mechanisms of Antibiotic Resistance and the Mobile Resistome in the Emerging Zoonotic Pathogen Streptococcus suis

  2021cites this paper
• Tight Interplay between Replication Stress and Competence Induction in Streptococcus pneumoniae

  2021cites this paper
• A Type I Restriction Modification System Influences Genomic Evolution Driven by Horizontal Gene Transfer in Paenibacillus polymyxa

  2021cites this paper
• The Role and Regulatory Network of the CiaRH Two-Component System in Streptococcal Species

  2021cites this paper
• Insights of metallic nanoparticles and ions in accelerating the bacterial uptake of antibiotic resistance genes.

  2021cites this paper
• Artificial sweeteners stimulate horizontal transfer of extracellular antibiotic resistance genes through natural transformation

  2021cites this paper
• Changes in natural transformation after salt adaptation

  2021cites this paper
• Genomic islands mediate environmental adaptation and the spread of antibiotic resistance in multiresistant Enterococci - evidence from genomic sequences

  2021cites this paper
• The pneumococcal alternative sigma factor σ X mediates competence shut-off at the cell pole

  2021influential citation
• Strategies to attenuate the competence regulon in Streptococcus pneumoniae

  2021cites this paper
• Genomic signatures of UV resistance evolution in Escherichia coli depend on the growth phase during exposure

  2021cites this paper
• Active Human and Porcine Serum Induce Competence for Genetic Transformation in the Emerging Zoonotic Pathogen Streptococcus suis

  2021cites this paper
• On (Un)naturalness

  2021cites this paper
• ComX improves acid tolerance by regulating the expression of late competence proteins in Lactococcus lactis F44.

  2021cites this paper
• Cadmium stress dictates central carbon flux and alters membrane composition in Streptococcus pneumoniae

  2020cites this paper
• Metallic nanoparticles and ions accelerate the uptake of extracellular antibiotic resistance genes through transformation

  2020cites this paper
• Accumulation of antibiotic resistance genes in full-scale drinking water biological activated carbon (BAC) filters during backwash cycles.

  2020cites this paper
• Increased expression of antibiotic-resistance genes in biofilm communities upon exposure to cetyltrimethylammonium bromide (CTAB) and other stress conditions.

  2020cites this paper
• Singularities of Pyogenic Streptococcal Biofilms – From Formation to Health Implication

  2020cites this paper
• The pneumococcal social network

  2020cites this paper
• Conceptualisation et exploitation d’un graphe de pangénome partitionné comme représentation compacte de la diversité du répertoire génique des espèces procaryotes

  2020cites this paper
• Efficient plasmid transfer via natural competence in a synthetic microbial community

  2020cites this paper
• Antimicrobial Resistance and Biofilm Formation of Pseudomonas aeruginosa

  2020cites this paper
• Cadmium stress dictates central carbon flux and alters membrane composition in Streptococcus pneumoniae

  2020cites this paper
• The Many Roles of the Bacterial Second Messenger Cyclic di-AMP in Adapting to Stress Cues

  2020cites this paper
• Progress Overview of Bacterial Two-Component Regulatory Systems as Potential Targets for Antimicrobial Chemotherapy

  2020cites this paper
• Histone-like Nucleoid-Structuring Protein (H-NS) Paralogue StpA Activates the Type I-E CRISPR-Cas System against Natural Transformation in Escherichia coli

  2020cites this paper
• Complement active human and porcine serum induces natural competence for genetic transformation in the emerging zoonotic pathogen Streptococcus suis

  2020cites this paper
• Natural Transformation in Deinococcus radiodurans: A Genetic Analysis Reveals the Major Roles of DprA, DdrB, RecA, RecF, and RecO Proteins

  2020cites this paper
• Unbiased homeologous recombination during pneumococcal transformation allows for multiple chromosomal integration events

  2020cites this paper
• Thresholds in Origin of Life Scenarios

  2020cites this paper
• Streptococcus pneumoniae Elaborates Persistent and Prolonged Competent State during Pneumonia-Derived Sepsis

  2020cites this paper
• The alternative sigma factor σX mediates competence shut-off at the cell pole in Streptococcus pneumoniae

  2020influential citation
• Selection Principles for Gaia.

  2019cites this paper
• Coordination of cohabiting phage elements supports bacteria–phage cooperation

  2019cites this paper
• Energy, environment and microbial survival

  2019cites this paper
• Multiple integration of the gene ganA into the Bacillus subtilis chromosome for enhanced β-galactosidase production using the CRISPR/Cas9 system

  2019cites this paper
• Harnessing the Potential of Killers and Altruists within the Microbial Community: A Possible Alternative to Antibiotic Therapy?

  2019cites this paper
• Mechanisms of DNA Uptake by Naturally Competent Bacteria.

  2019cites this paper
• DprA-Dependent Exit from the Competent State Regulates Multifaceted Streptococcus pneumoniae Virulence

  2019cites this paper
• Bacterial Second Messenger Cyclic di-AMP Modulates the Competence State in Streptococcus pneumoniae

  2019cites this paper