Nitric oxide generation by the organic nitrate NDBP attenuates oxidative stress and angiotensin II‐mediated hypertension

No abstract is available for this paper.

• Publication year

  2016

• Venue

  British Journal of Pharmacology

• Publication date

  2016-07-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1111/bph.13511PMID 27160064PMCID PMC4919584
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2006influential reference
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  2005influential reference
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  year unknowninfluential reference

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