A genetic variant in IL‐15Rα correlates with physical activity among European–American adults

M. Bruneau,S. Walsh,Eric Selinsky,Garrett I. Ash,T. Angelopoulos,P. Clarkson,P. Gordon,N. Moyna,P. Visich,R. Zoeller,P. Thompson,H. Gordish-Dressman,E. Hoffman,J. Devaney,L. Pescatello

Published 2018 in Molecular Genetics & Genomic Medicine

ABSTRACT

Interleukin‐15 (IL‐15) is a myokine associated with muscle strength, possibly by attenuating protein breakdown. A variant in the alpha‐receptor (IL‐15Rα 1775 A>C, rs2228059) partially modulates the muscle strength and size response to resistance training. We examined if this polymorphism associated with habitual physical activity among European‐American adults.

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