Peripheral Blood Fibrocytes: Differentiation Pathway and Migration to Wound Sites1

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Journal of Immunology

• Publication date

  2001-06-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.166.12.7556PMID 11390511
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Fibroblast heterogeneity in physiological conditions and fibrotic disease

  2004cited by this paper
• Transforming growth factor-beta1 promotes the morphological and functional differentiation of the myofibroblast.

  2000cited by this paper
• Lymphoid tissue homing chemokines are expressed in chronic inflammation.

  2000cited by this paper
• Myofibroblasts: paracrine cells important in health and disease.

  2000cited by this paper
• Interaction of Borrelia burgdorferi with Peripheral Blood Fibrocytes, Antigen-Presenting Cells with the Potential for Connective Tissue Targeting

  1999cited by this paper
• Exogenous transforming growth factor beta(2) modulates collagen I and collagen III synthesis in proliferative scar xenografts in nude rats.

  1999cited by this paper
• Myofibroblasts . I . Paracrine cells important in health and disease

  1999cited by this paper
• Chemokine amplification in mesangial cells.

  1999influential reference
• Inhibition of Myofibroblast Apoptosis by Transforming Growth Factor β1

  1999cited by this paper
• The compliance of collagen gels regulates transforming growth factor-β induction of α-smooth muscle actin in fibroblasts

  1999cited by this paper
• TGF- and fibrosis

  1999cited by this paper
• Mice Lacking Expression of Secondary Lymphoid Organ Chemokine Have Defects in Lymphocyte Homing and Dendritic Cell Localization

  1999cited by this paper
• Final maturation of dendritic cells is associated with impaired responsiveness to IFN-gamma and to bacterial IL-12 inducers: decreased ability of mature dendritic cells to produce IL-12 during the interaction with Th cells.

  1999cited by this paper
• Cutting edge: secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes.

  1999cited by this paper
• Mechanisms of myofibroblast activity and phenotypic modulation.

  1999cited by this paper
• The deletion of transforming growth factor-beta-induced myofibroblasts depends on growth conditions and actin organization.

  1999cited by this paper
• Dendritic cells require T cells for functional maturation in vivo.

  1999cited by this paper
• Anti-TGF-beta treatment prevents skin and lung fibrosis in murine sclerodermatous graft-versus-host disease: a model for human scleroderma.

  1999cited by this paper
• Up-regulation by human recombinant transforming growth factor beta-1 of collagen production in cultured dermal fibroblasts is mediated by the inhibition of nitric oxide signaling.

  1999cited by this paper
• Overproduction of Th2-specific chemokines in NC/Nga mice exhibiting atopic dermatitis-like lesions.

  1999cited by this paper
• A novel mutant gene involved in T-lymphocyte-specific homing into peripheral lymphoid organs on mouse chromosome 4.

  1998cited by this paper
• Pivotal role of TARC, a CC chemokine, in bacteria-induced fulminant hepatic failure in mice.

  1998influential reference
• Regulated production of type I collagen and inflammatory cytokines by peripheral blood fibrocytes.

  1998cited by this paper
• Molecular cloning, functional characterization and mRNA expression analysis of the murine chemokine receptor CCR6 and its specific ligand MIP‐3α 1

  1998influential reference
• Skeletal and smooth muscle alpha-actin mRNA in endomyocardial biopsy samples of dilated cardiomyopathy patients.

  1998cited by this paper
• The Role of α1β1 Integrin in Wound Contraction

  1997cited by this paper
• The peripheral blood fibrocyte is a potent antigen-presenting cell capable of priming naive T cells in situ.

  1997cited by this paper
• Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.

  1997cited by this paper
• Genetic defect in T lymphocyte‐specific homing into peripheral lymph nodes

  1997cited by this paper
• Differentiation of human dendritic cells from monocytes in vitro

  1997cited by this paper
• Peripheral blood fibrocytes: novel fibroblast-like cells that present antigen and mediate tissue repair.

  1997cited by this paper
• The role of alpha1beta1 integrin in wound contraction. A quantitative analysis of liver myofibroblasts in vivo and in primary culture.

  1997cited by this paper
• A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

  1996cited by this paper
• Molecular and functional characteristics of dendritic cells generated from highly purified CD14+ peripheral blood monocytes.

  1996cited by this paper
• CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells.

  1996cited by this paper
• Particle-mediated gene transfer with transforming growth factor-beta1 cDNAs enhances wound repair in rat skin.

  1996cited by this paper
• Dendritic cells differentiated from human monocytes through a combination of IL-4, GM-CSF and IFN-gamma exhibit phenotype and function of blood dendritic cells.

  1995cited by this paper
• Circulating Fibrocytes Define a New Leukocyte Subpopulation That Mediates Tissue Repair

  1994influential reference
• Transforming growth factor β levels in rat wound chambers

  1987cited by this paper
• The Fibroblast — A Ubiquitous Ally for the Surgeon

  1963cited by this paper

• From fibrotic mechanisms to clinical translation: the drug therapy revolution and delivery system breakthrough in proliferative vitreoretinopathy.

  2026cites this paper
• Circulating Fibrocytes: Cellular Mediators of Tissue Fibrosis

  2026influential citation
• FAP-Synergistic Organ-Targeted mRNA-LNP for Overcoming Delivery Barriers in Hepatic and Pulmonary Fibrosis.

  2026cites this paper
• From blood to pluripotency: Fibrocytes as a reprogrammable somatic cell source for bovine iPSCs

  2025cites this paper
• Macrophages and Pulmonary Fibrosis.

  2025cites this paper
• SPHK1-S1p Signaling Drives Fibrocyte-Mediated Pulmonary Fibrosis: Mechanistic Insights and Therapeutic Potential

  2025cites this paper
• Cellular crosstalk in fibrosis: Insights into macrophage and fibroblast dynamics

  2025cites this paper
• CAR-engineered cytolytic Tregs reverse pulmonary fibrosis and remodel the fibrotic niche with limited CRS

  2025cites this paper
• Mesangiogenic progenitor cells: a mesengenic and vasculogenic branch of hemopoiesis? A story of neglected plasticity

  2025cites this paper
• Enhanced apoptosis, inflammatory cellularity, collagen deposition, and interaction between fibroblasts and Leishmania amastigotes in undamaged ear skin of dogs with leishmaniosis.

  2025cites this paper
• Modern strategies for the prevention and treatment of post-burn scars (a systematic review)

  2025cites this paper
• From Wound Dressing to Tissue Regeneration: Bilayer Medicated Patches for Personalized Treatments of Chronic Wounds

  2025cites this paper
• Liver Fibrosis: Interactions Between Cells and Microenvironments

  2025cites this paper
• Construction of functional tissue-engineered microvasculatures using circulating fibrocytes as mural cells

  2025cites this paper
• An extracellular matrix coating similar to articular cartilage inhibits the differentiation of myofibroblasts and limits the development of implant-induced fibrosis

  2025cites this paper
• Pulmonary Thromboembolism Due to Intravenous Fibrocyte Administration in C57BL/6J Mice (Mus musculus) and Recommendations for Refinement.

  2025cites this paper
• Inhibition of Talin2 dedifferentiates myofibroblasts and reverses lung and kidney fibrosis

  2025cites this paper
• Clock pathway inhibitor overcomes tumor immune-exclusion via regulation of fibrocyte differentiation

  2025cites this paper
• Celecoxib inhibits skin fibrosis via suppressing adipocyte progenitor-myofibroblast transdifferentiation by attenuating the YAP/TAZ signaling pathway.

  2025cites this paper
• Regulatory mechanisms of macrophage-myofibroblast transdifferentiation: A potential therapeutic strategy for fibrosis.

  2024cites this paper
• Inflammatory Markers Involved in the Pathogenesis of Dupuytren's Contracture.

  2024cites this paper
• Autologous platelet-rich fibrin enhances skin wound healing in a feline trauma model

  2024cites this paper
• Serum amyloid P (PTX2) attenuates hepatic fibrosis in mice by inhibiting the activation of fibrocytes and HSCs

  2024influential citation
• Amplified response of drug-induced liver fibrosis via immune cell co-culture in a 3D in vitro hepatic fibrosis model.

  2024cites this paper
• Multi‐organ single‐cell RNA sequencing in mice reveals early hyperglycemia responses that converge on fibroblast dysregulation

  2024cites this paper
• TSHR-IGF-IR complex drives orbital fibroblast misbehavior in thyroid eye disease.

  2024cites this paper
• Liver fibrosis pathologies and potentials of RNA based therapeutics modalities

  2024cites this paper
• Role of Circulating Monocytes and Periodontopathic Bacteria in Pathophysiology of Rheumatoid Arthritis.

  2024cites this paper
• Recognition of HIV-1-infected fibrocytes lacking Nef-mediated HLA-B downregulation by HIV-1-specific T cells

  2024cites this paper
• Not an immune cell, but they may act like one—cells with immune properties outside the immune system

  2024cites this paper
• Immune cells crosstalk Pathways, and metabolic alterations in Idiopathic pulmonary fibrosis.

  2024cites this paper
• Stem Cells and Regenerative Strategies for Wound Healing: Therapeutic and Clinical Implications

  2024cites this paper
• Fascial Nomenclature: Update 2024

  2024cites this paper
• Blocking antibodies against integrin-α3, -αM, and -αMβ2 de-differentiate myofibroblasts, and improve lung fibrosis and kidney fibrosis

  2024cites this paper
• FGFR-related phenotypic and functional profile of CAFs in prognostication of breast cancer (Review)

  2024cites this paper
• Role of pH-sensing receptors in colitis

  2024cites this paper
• The Effects of Tissue Healing Factors in Wound Repair Involving Absorbable Meshes: A Narrative Review

  2023cites this paper
• Cancer-Associated Fibroblasts: Heterogeneity and Bimodality in Oncogenesis

  2023cites this paper
• Roles of four targets in the pathogenesis of graves' orbitopathy

  2023cites this paper
• Multi-organ single-cell RNA-sequencing reveals early hyperglycaemia responses that converge on fibroblast dysregulation

  2023cites this paper
• Glycyrrhetinic acid mitigates radiation-induced pulmonary fibrosis via inhibiting the secretion of TGF-β1 by Treg cells.

  2023cites this paper
• Fibrosis in Burns: an Overview of Mechanisms and Therapies.

  2023cites this paper
• Fibrocytes enhance mammary gland fibrosis in obesity

  2023cites this paper
• A2BAR Antagonism Decreases the Glomerular Expression and Secretion of Chemoattractants for Monocytes and the Pro-Fibrotic M2 Macrophages Polarization during Diabetic Nephropathy

  2023cites this paper
• Promising small molecule anti-fibrotic agents: newly developed or repositioned drugs targeting myofibroblast transdifferentiation.

  2023cites this paper
• Mapping intellectual structure and research hotspots in the field of fibroblast-associated DFUs: a bibliometric analysis

  2023cites this paper
• Preliminary study of some of the main intratumor stroma components in gastric carcinomas.

  2023cites this paper
• Immune Mechanisms of Pulmonary Fibrosis with Bleomycin

  2023cites this paper
• CC Chemokines in Idiopathic Pulmonary Fibrosis: Pathogenic Role and Therapeutic Potential

  2023cites this paper
• Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade.

  2023cites this paper
• Overlapping between Wound Healing Occurring in Tumor Growth and in Central Nervous System Neurodegenerative Diseases

  2023cites this paper
• Development of Adaptive Immunity and Its Role in Lung Remodeling.

  2023cites this paper
• Short-range interactions between fibrocytes and CD8+ T cells in COPD bronchial inflammatory response

  2023cites this paper
• Thou shall not heal: Overcoming the non-healing behaviour of diabetic foot ulcers by engineering the inflammatory microenvironment.

  2023cites this paper
• Tryptase and Exogenous Trypsin: Mechanisms and Ophthalmic Applications

  2023cites this paper
• Review of optical methods for noninvasive imaging of skin fibroblasts—From in vitro to ex vivo and in vivo visualization

  2023cites this paper
• Alterations in the mammary gland and tumor microenvironment of formerly obese mice

  2023cites this paper
• Retracted Article: Study of 1550nm Erbium Glass Laser Fractional non-ablative treatment of photoaging: comparative clinical effects, histopathology, electron microscopy and immunohistochemistry

  2023cites this paper
• Obesity and Fibrosis: Setting the Stage for Breast Cancer

  2023cites this paper
• Role of Circulating Hematopoietic Fibrocytes in Chronic Hepatitis C Patients Induced Liver Fibrosis

  2022cites this paper
• Heterogeneity and dynamic of EMT through the plasticity of ribosome and mRNA translation.

  2022cites this paper
• [Regulatory effects of bio-intensity electric field on transformation of human skin fibroblasts].

  2022cites this paper
• Macrophage orchestration of epithelial and stromal cell homeostasis in the intestine

  2022cites this paper
• Targeting fibrocytes in autoimmunity

  2022cites this paper
• Fibrotic Scar in CNS Injuries: From the Cellular Origins of Fibroblasts to the Molecular Processes of Fibrotic Scar Formation

  2022cites this paper
• Bone Marrow-Derived Cells and Wound Age Estimation

  2022influential citation
• Circulating and renal fibrocytes are associated with interstitial fibrosis in lupus nephritis.

  2022cites this paper
• Targeting Inflammation to Control Tissue Fibrosis

  2022cites this paper
• Role of Immune Cells in the Initiation and Progression of Pulmonary Fibrosis.

  2022cites this paper
• The Yin and Yang of Mesenchymal Cells in the Corneal Stromal Fibrosis Response to Injury: The Cornea as a Model of Fibrosis in Other Organs

  2022cites this paper
• Exosomal long non-coding RNAs: novel molecules in gastrointestinal cancers’ progression and diagnosis

  2022cites this paper
• Proportion of Concentrate in the Diet of Early Lactation Dairy Cows Has Contrasting Effects on Circulating Leukocyte Global Transcriptomic Profiles, Health and Fertility According to Parity

  2022cites this paper
• CHARACTERIZATION OF CIRCULATING FIBROCYTES IN PEOPLE LIVING WITH HIV A THESIS SUBMITTED TO THE GRADUATE DIVISION OF THE UNIVERITY OF HAWAII AT MANOA IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF MASTER OF SCIENCE

  2022influential citation
• Analysis of the chemotactic factors for tumor-infiltrating fibrocytes and their prognostic significances in lung cancer

  2022cites this paper
• Stem Cell-Based Therapeutic Strategies in Diabetic Wound Healing

  2022cites this paper
• Characterization of Circulating Fibrocytes in People Living with HIV on Stable Antiretroviral Therapy

  2022cites this paper
• Macrophage Phenotypes in Normal and Diabetic Wound Healing and Therapeutic Interventions

  2022cites this paper
• Wound healing, fibroblast heterogeneity, and fibrosis.

  2022cites this paper
• Identification and characterization of FGFR2+ hematopoietic stem cell-derived fibrocytes as precursors of cancer-associated fibroblasts induced by esophageal squamous cell carcinoma

  2022cites this paper
• Bone marrow fibrocytes: villain or white knight in thyroid-associated ophthalmopathy?

  2022cites this paper
• Evidence for the in vivo existence and mobilisation of myeloid angiogenic cells and pericyte‐like cells in wound patients after skin grafting

  2022cites this paper
• Increased Expression of Galectin-3 in Skin Fibrosis: Evidence from In Vitro and In Vivo Studies

  2022cites this paper
• Possible Role of Circulating Bone Marrow Mesenchymal Progenitors in Modulating Inflammation and Promoting Wound Repair

  2021cites this paper
• Fibrocytes: A Critical Review and Practical Guide

  2021cites this paper
• Therapeutic IGF-I receptor inhibition alters fibrocyte immune phenotype in thyroid-associated ophthalmopathy

  2021cites this paper
• Understanding the Role of Fibroblasts following a 3D Tumoroid Implantation for Breast Tumor Formation

  2021cites this paper
• Blood fibrocytes are associated with severity and prognosis in COVID-19 pneumonia

  2021cites this paper
• Bifunctional Peptide that Anneals to Damaged Collagen and Clusters TGF-β Receptors Enhances Wound Healing

  2021cites this paper
• After Effects of COVID-19 and Repair of Lungs

  2021cites this paper
• Review of the Latest Methods in the Treatment of Epidermolysis Bullosa and Other Chronic Wounds, Development of Innovative Advanced Therapy Medicinal Product

  2021cites this paper
• Association of Circulating Fibrocytes With Fibrostenotic Small Bowel Crohn's Disease.

  2021cites this paper
• Myofibroblast differentiation is governed by adhesion mechanics, and inhibition of Talin2 reverses lung and kidney fibrosis

  2021cites this paper
• Anti‐IgE therapy inhibits chemotaxis, proliferation and transformation of circulating fibrocytes in patients with severe allergic asthma

  2021cites this paper
• Classification of Wounds and the Physiology of Wound Healing

  2021cites this paper
• Blocking antibodies against integrin-α3, -αM, and -αMβ2 de-differentiate myofibroblasts and reverse lung and kidney fibroses

  2021cites this paper
• Systemic Fibrocyte Levels and Keloid Expression of the Chemoattractant CXCL12 Are Upregulated Compared With Patients With Normal Scar

  2021cites this paper
• Histologic, immunohistochemical, and scanning electron microscopic comparison of pre-iridal monocellular and fibrovascular membranes in normal and glaucomatous canine globes.

  2021cites this paper
• The Role of Pro-fibrotic Myofibroblasts in Systemic Sclerosis: from Origin to Therapeutic Targeting.

  2021cites this paper
• Circulating Fibrocyte Level in Children with Cystic Fibrosis.

  2021cites this paper
• Blockade of PD-1/PD-L1 Pathway Enhances the Antigen-Presenting Capacity of Fibrocytes

  2021cites this paper