Cytoplasmic localization of p120ctn and E-cadherin loss characterize lobular breast carcinoma from preinvasive to metastatic lesions

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Oncogene

• Publication date

  2004-04-22

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.onc.1207439PMID 15077190
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2003cited by this paper
• The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors

  2003cited by this paper
• Up-regulation, nuclear import, and tumor growth stimulation of the adhesion protein p120 in pancreatic cancer.

  2003cited by this paper
• Effects of E‐cadherin transfection on gene expression of a gallbladder carcinoma cell line: Repression of MTS1/S100A4 gene expression

  2003cited by this paper
• Abnormal α‐catenin expression in invasive breast cancer correlates with poor patient survival

  2002cited by this paper
• Abnormal alpha-catenin expression in invasive breast cancer correlates with poor patient survival.

  2002cited by this paper
• A novel role for p120 catenin in E-cadherin function

  2002cited by this paper
• Specific sequences in p120ctn determine subcellular distribution of its multiple isoforms involved in cellular adhesion of normal and malignant epithelial cells.

  2002cited by this paper
• Altered expression of the catenin p120 in human cancer: implications for tumor progression.

  2002influential reference
• Abnormalities of the APC/β-catenin pathway in endometrial cancer

  2002cited by this paper
• Abnormalities of the APC/beta-catenin pathway in endometrial cancer.

  2002cited by this paper
• The cadherin-catenin adhesion system in signaling and cancer.

  2002cited by this paper
• Tyrosine phosphorylation of p120(ctn) in v-Src transfected L cells depends on its association with E-cadherin and reduces adhesion activity.

  2001cited by this paper
• Molecular architecture of adherens junctions.

  2001cited by this paper
• The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor.

  2001cited by this paper
• Regulation of Rho GTPases by p120-catenin.

  2001cited by this paper
• A New Role for E12/E47 in the Repression ofE-cadherin Expression and Epithelial-Mesenchymal Transitions*

  2001cited by this paper
• Tissue Distribution and Cell Type-specific Expression of p120ctn Isoforms

  2001cited by this paper
• Identification of Src Phosphorylation Sites in the Catenin p120 ctn *

  2001cited by this paper
• Multiple ways of silencing E‐cadherin gene expression in lobular carcinoma of the breast

  2001cited by this paper
• Stimulation of c-Src by prolactin is independent of Jak2.

  2000cited by this paper
• Inhibition of RhoA by p120 catenin

  2000cited by this paper
• The E-cadherin-catenin complex in tumour metastasis: structure, function and regulation.

  2000cited by this paper
• Selective Uncoupling of P120ctn from E-Cadherin Disrupts Strong Adhesion

  2000cited by this paper
• E-cadherin complex and its abnormalities in human breast cancer.

  2000cited by this paper
• The p120 catenin family: complex roles in adhesion, signaling and cancer.

  2000cited by this paper
• The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression

  2000cited by this paper
• Atypical lobular hyperplasia and lobular carcinoma in situ: surgical and molecular pathology

  1999cited by this paper
• N‐cadherin‐mediated adhesion and aberrant catenin expression in anaplastic thyroid‐carcinoma cell lines

  1999cited by this paper
• N-Cadherin expression in human prostate carcinoma cell lines. An epithelial-mesenchymal transformation mediating adhesion withStromal cells.

  1999cited by this paper
• Regulation of E-cadherin/Catenin Association by Tyrosine Phosphorylation*

  1999cited by this paper
• Nuclear localization of the p120(ctn) Armadillo-like catenin is counteracted by a nuclear export signal and by E-cadherin expression.

  1999influential reference
• The Catenin p120ctnInteracts with Kaiso, a Novel BTB/POZ Domain Zinc Finger Transcription Factor

  1999cited by this paper
• The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene.

  1999cited by this paper
• Up‐regulated cytoplasmic expression, with reduced membranous distribution, of the src substrate p120ctn in gastric carcinoma

  1999cited by this paper
• Mutations of the human E‐cadherin (CDH1) gene

  1998cited by this paper
• Molecular cloning of the human p120ctn catenin gene (CTNND1): expression of multiple alternatively spliced isoforms.

  1998cited by this paper
• Tyrosine phosphorylation and cadherin/catenin function

  1997cited by this paper
• The tyrosine kinase substrate p120cas binds directly to E-cadherin but not to the adenomatous polyposis coli protein or alpha-catenin

  1995cited by this paper
• Correlation of E-cadherin expression with differentiation grade and histological type in breast carcinoma.

  1993cited by this paper

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  2024cites this paper
• "Lobular lesions of the breast: From the classic to the variants".

  2024cites this paper
• Canonical Kaiso target genes define a functional signature that associates with breast cancer survival and the invasive lobular carcinoma histological type

  2023cites this paper
• The E3 ubiquitin ligase MIB1 suppresses breast cancer cell migration through regulating CTNND1 protein level.

  2023cites this paper
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  2023cites this paper
• Correspondence on: "Standardization in the diagnosis of invasive lobular carcinoma of the breast".

  2023cites this paper
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  2022cites this paper
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  2022cites this paper
• Special Histologic Type and Rare Breast Tumors - Diagnostic Review and Clinico-Pathological Implications.

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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
• α-catenin, β-catenin and P-120-catenin immunoexpression in canine mammary tissues and their relationship with E-cadherin.

  2020cites this paper
• P120 and E-cadherin: double-edged swords in tumor metastasis.

  2020cites this paper
• American registry of pathology expert opinions: The spectrum of lobular carcinoma in situ: Diagnostic features and clinical implications.

  2020cites this paper
• Single-Cell Transcriptomic Heterogeneity in Invasive Ductal and Lobular Breast Cancer Cells

  2020cites this paper
• Pathology of Breast Cancer

  2019cites this paper
• P120 catenin expression and its correlation with E-cadherin in salivary gland neoplasms.

  2019cites this paper
• Lobular Breast Lesions

  2019cites this paper
• P120 Catenin Isoforms Differentially Associate with Breast Cancer Invasion and Metastasis

  2019influential citation
• hsa_circ_0000745 promotes cervical cancer by increasing cell proliferation, migration, and invasion

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• Pathology of Breast Cancer

  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
• Core Needle Biopsy of the Breast: An Evaluation of Contemporary Data.

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  2017cites this paper
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  2017cites this paper
• Lobular Carcinoma In Situ.

  2017cites this paper
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  2017cites this paper
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  2016cites this paper
• Invasive Lobular Carcinoma

  2016cites this paper
• Lobular breast cancer: Clinical, molecular and morphological characteristics.

  2016cites this paper
• Beyond a tumor suppressor: Soluble E‐cadherin promotes the progression of cancer

  2016cites this paper
• WNT4 mediates estrogen receptor signaling and endocrine resistance in invasive lobular carcinoma cell lines

  2016cites this paper
• Clinical Applications for Immunohistochemistry of Breast Lesions.

  2016cites this paper
• Phosphorylation and isoform use in p120-catenin during development and tumorigenesis.

  2016cites this paper
• p120-Catenin Is Critical for the Development of Invasive Lobular Carcinoma in Mice

  2016cites this paper
• Lobular breast cancer: molecular basis, mouse and cellular models

  2015cites this paper
• Atypical and Malignant Breast Pathology

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• Methylation biomarkers for pleomorphic lobular breast cancer - a short report

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• Catenin‐δ1, negatively regulated by miR‐145, promotes tumour aggressiveness in gastric cancer

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• Molecular Pathology of Lobular Carcinoma

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• Morphometric Analysis in the Diagnosis of Low-Grade Ductal and Lobular Carcinoma in Situ of the Breast.

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  2014cites this paper
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  2014cites this paper
• Application of immunohistochemistry in breast pathology: a review and update.

  2014cites this paper
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  2014cites this paper
• p120catenin alteration in cancer and its role in tumour invasion

  2013cites this paper
• Circulating Biomarkers for Esophageal Squamous Cell Carcinoma

  2013cites this paper
• Posttranscriptional regulation by RNA-binding proteins during epithelial-to-mesenchymal transition

  2013cites this paper
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  2013cites this paper
• E-cadherin expression in molecular types of breast carcinoma.

  2013cites this paper
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• Is expression of p120ctn in oral squamous cell carcinomas a prognostic factor?

  2013cites this paper
• p120 catenin: an essential regulator of cadherin stability, adhesion-induced signaling, and cancer progression.

  2013cites this paper
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  2013cites this paper
• Lobular Breast Cancer: Pathology, Biology, and Options for Clinical Intervention

  2013cites this paper
• The classification of invasive carcinoma of the breast

  2013cites this paper
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• Further evidence that E‐cadherin is not a tumour suppressor gene in invasive ductal carcinoma of the breast: an immunohistochemical study

  2013influential citation
• MOLECULAR SUBTYPES IN BREAST CANCER

  2013cites this paper
• Immunohistochemistry Applied to the Differential Diagnosis Between Ductal and Lobular Carcinoma of the Breast

  2012cites this paper
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  2012cites this paper
• Functions of p120ctn isoforms in cell-cell adhesion and intracellular signaling.

  2012cites this paper
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  2012cites this paper