SUPPRESSOR CELLS IN TRANSPLANTATION TOLERANCE I. SUPPRESSOR CELLS IN THE MECHANISM OF TOLERANCE IN RADIATION CHIMERAS

No abstract is available for this paper.

• Publication year

  1981

• Venue

  Transplantation

• Publication date

  1981-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/00007890-198109000-00005PMID 6456580
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Specific suppressor cells and immune response to host antigens in long-term human allogeneic marrow recipients: implications for the mechanisms of graft-host tolerance and chronic graft-versus-host disease.

  1981cited by this paper
• Studies on the mechanism of transplantation tolerance. I. Do suppressor cells play a role in the induction and maintenance of neonatal transplantation tolerance?

  1980cited by this paper
• Regulation of experimental allergic encephalomyelitis. II. Appearance of suppressor cells during the remission phase of the disease.

  1980cited by this paper
• Role of suppressor cells in transplantation tolerance.

  1979cited by this paper
• Rosette formation between rat thymocytes and guinea pig erythrocytes requires "active" fetal calf serum. II. Characterization of the receptor-bearing thymocytes.

  1978cited by this paper
• Specific suppression of antigen-reactive cells in neonatal transplantation tolerance

  1978cited by this paper
• Macrophages suppress CTL generation in rat mixed leukocyte cultures.

  1977cited by this paper
• BONE MARROW TRANSPLANTATION IN THE BUSULFAN‐TREATED RAT: III. RELATIONSHIP BETWEEN MYELOSUPPRESSION AND IMMUNOSUPPRESSION FOR CONDITIONING BONE MARROW RECIPIENTS

  1977cited by this paper
• The antigen‐inexperienced thymic suppressor cells: a class of lymphocytes in the young chicken thymus that inhibits antibody production and cell‐mediated immune responses

  1976cited by this paper
• SPECIFIC positive and negative selection of rat lymphocytes reactive to strong histocompatibility antigens: activation with alloantigens in vitro and in vivo.

  1976cited by this paper
• Transplantation tolerance.

  1976cited by this paper
• Infusion of donor lymphocytes into stable canine radiation chimeras: implications for mechanism of transplantation tolerance.

  1976cited by this paper
• H-2 restriction of virus-specific cytotoxicity across the H-2 barrier. Separate effector T-cell specificities are associated with self-H-2 and with the tolerated allogeneic H-2 in chimeras

  1976cited by this paper
• Status of T- and B-cell cooperation in radiation chimeras: evidence for a suppressor effect.

  1976cited by this paper
• Neonatally induced transplantation tolerance: in vitro evidence supporting a clonal inactivation mechanism

  1975cited by this paper
• Association of immunity and tolerance to host H-2 determinants in irradiated F1 hybrid mice reconstituted with bone marrow cells from one parental strain

  1975cited by this paper
• T cells mediate transplantation tolerance

  1975cited by this paper
• BONE MARROW TRANSPLANTATION IN THE BUSULFAN‐TREATED RAT: II. EFFECT OF CYCLOPHOSPHAMIDE AND ANTITHYMIC SERUM ON THE PRESENSITIZED STATE

  1975cited by this paper
• Canine marrow transplantation: are serum blocking factors necessary to maintain the stable chimeric state?

  1975cited by this paper
• Graft-versus-host reactivity and inhibitory serum factors in allograft-tolerant chickens.

  1975cited by this paper
• CELL‐MEDIATED REACTIVITY AND SERUM BLOCKING ACTIVITY IN TOLERANT RATS STUDIES ON TEN RATS OPERATIONALLY TOLERANT TO SKIN ALLOGRAFTS USING SEVERAL INDPENDENT ASSAYS

  1974cited by this paper
• TOLERANCE INDUCTION TO A HETEROTOPIC CARDIAC ALLOGRAFT IN THE IRRADIATED RECONSTITUTED MOUSE

  1974cited by this paper
• Immuno-regulatory role of spleen localizing thymocytes.

  1974cited by this paper
• The influence of removing lymphoid tissue on the persistence of tolerance of skin allografts in mice.

  1974cited by this paper
• Cellular immunity and blocking serum activity in chimeric mice.

  1973cited by this paper
• In vitro reactivity of lymphoid cells from tolerant mice.

  1973cited by this paper
• ACTIVE SUPPRESSION AS A POSSIBLE MECHANISM OF TOLERANCE IN TETRAPARENTAL MICE

  1973cited by this paper
• IS TRANSPLANTATION TOLERANCE IN THE RAT SERUM‐MEDIATED?

  1973cited by this paper
• Induction of T cell tolerance in agammaglobulinemic chickens

  1972cited by this paper
• Immunological tolerance: "forbidden clones" allowed in tetraparental mice.

  1971cited by this paper
• Serum-mediated Immunological Non-reactivity between Histoincompatible Cells in Tetraparental Mice

  1971cited by this paper
• STUDIES ON THE APPARENT SERIAL PASSAGE OF TRANSPLANTATION IMMUNITY IN TOLERANT MICE

  1970cited by this paper
• Colony inhibition of fibroblasts from chimeric dogs mediated by the dogs' own lymphocytes and specifically abrogated by their serum.

  1970cited by this paper
• PROTECTION AGAINST HOMOLOGOUS DISEASE IN HYBRID MICE BY PASSIVE AND ACTIVE IMMUNOLOGICAL ENHANCEMENT‐FACILITATION

  1968cited by this paper
• ‘Actively Acquired Tolerance’ of Foreign Cells

  1953cited by this paper

• The Role of Animal Models in the Study of Hematopoietic Stem Cell Transplantation and GvHD: A Historical Overview

  2016cites this paper
• CD4+CD25+ T Regulatory Cells in Transplantation Tolerance: 25 Years On

  2016cites this paper
• CD4+CD25+ T Regulatory Cells in Transplantation Tolerance: 25 Years On.

  2016cites this paper
• irradiation, and posttransplantation cyclophosphamide after nonmyeloablative conditioning with fludarabine, low-dose total body incompatible cells - Durable engraftment of major histocompatibility complex

  2013cites this paper
• graft-versus-leukemia reactivity of donor lymphocyte infusions possible implications for the graft-versus-host and suppressor activity in spleens of murine radiation marrow chimeras: Transient expansion of Mac1+Ly6-G+Ly6-C+ early myeloid cells with

  2013cites this paper
• infused after allogeneic bone marrow transplantation in the mouse Factors governing the activation of adoptively transferred donor T-cells

  2013cites this paper
• Reconstitution of self-tolerance after hematopoietic stem cell transplantation

  2010cites this paper
• This information is current as Experimental Graft-versus-Host Disease T Cell-Mediated Suppression of Regulatory + CD 25 + Induction of Donor CD 4 A Crucial Role for Host APCs in the

  2010cites this paper
• A Crucial Role for Host APCs in the Induction of Donor CD4+CD25+ Regulatory T Cell-Mediated Suppression of Experimental Graft-versus-Host Disease

  2010cites this paper
• receiving allogeneic bone marrow transplants mice dissociated graft-versus-host and graft-versus-leukemia responses in Crucial role of timing of donor lymphocyte infusion in generating

  2007cites this paper
• Factors governing the activation of adoptively transferred donor T cells infused after allogeneic bone marrow transplantation in the mouse.

  2007cites this paper
• Modulation of graft-versus-host disease: role of regulatory T lymphocytes.

  2006cites this paper
• Thalidomide derivatives and the immune system. I. Changes in the pattern of integrin receptors and other surface markers on T lymphocyte subpopulations of marmoset blood

  2005cites this paper
• Transient expansion of Mac1+Ly6-G+Ly6-C+ early myeloid cells with suppressor activity in spleens of murine radiation marrow chimeras: possible implications for the graft-versus-host and graft-versus-leukemia reactivity of donor lymphocyte infusions.

  2003cites this paper
• Crucial role of timing of donor lymphocyte infusion in generating dissociated graft-versus-host and graft-versus-leukemia responses in mice receiving allogeneic bone marrow transplants.

  2002cites this paper
• Mechanisms of Alloimmune Tolerance Associated with Mixed Chimerism Induced by Vascularized Bone Marrow Transplants

  2002cites this paper
• MECHANISMS OF TOLERANCE INDUCED BY PG490‐88 IN A BONE MARROW TRANSPLANTATION MODEL

  2002cites this paper
• Durable engraftment of major histocompatibility complex-incompatible cells after nonmyeloablative conditioning with fludarabine, low-dose total body irradiation, and posttransplantation cyclophosphamide.

  2001cites this paper
• Infusions Disease Mediated by Donor Leukocyte Host T Cells Resist Graft-Versus-Host

  2000cites this paper
• Host T Cells Resist Graft-Versus-Host Disease Mediated by Donor Leukocyte Infusions1

  2000cites this paper
• Role of immunoregulatory donor T cells in suppression of graft-versus-host disease following donor leukocyte infusion therapy.

  1999cites this paper
• Following Donor Leukocyte Infusion Therapy Suppression of Graft-Versus-Host Disease Role of Immunoregulatory Donor T Cells in

  1999cites this paper
• Graft-versus-Host Disease

  1998cites this paper
• Thalidomide Inhibits Tumor Necrosis Factor a, Decreases Nitric Oxide Synthesis, and Ameliorates the Hyperdynamic Circulatory Syndrome in Portal-Hypertensive Rats

  1998cites this paper
• Adoptive immunotherapy in canine chimeras.

  1997cites this paper
• Thalidomide inhibits tumor necrosis factor α, decreases nitric oxide synthesis, and ameliorates the hyperdynamic circulatory syndrome in portal‐hypertensive rats

  1996cites this paper
• Prevention of lethal graft-versus-host disease in mice by monoclonal antibodies directed against T cells or their subsets. I. Evidence for the induction of a state of tolerance based on suppression.

  1994cites this paper
• Dietary fish oil supplementation alters LTB4:LTB5 ratios but does not affect the expression of acute graft versus host disease in mice.

  1993cites this paper
• Analysis of the mechanism of graft-versus-host-like disease in B6 mice with transferred B6-lpr spleen cells.

  1991cites this paper
• Cytotoxic and proliferative T-cell clones with antidonor reactivity from a patient transplanted for severe combined immunodeficiency disease.

  1990cites this paper
• Effect of thalidomide on the incidence of iodine-induced and spontaneous lymphocytic thyroiditis and spontaneous diabetes mellitus in the BB/Wor rat.

  1990cites this paper
• Chronic graft-versus-host disease.

  1990cites this paper
• Cyclosporin A and bone marrow transplantation

  1989cites this paper
• The mechanism of graft-host-tolerance in murine radiation chimeras transplanted across minor histocompatibility barriers.

  1989cites this paper
• Immune tolerance of intestinal allografts in the rat.

  1989cites this paper
• Graft Host Interactions Following T-Cell Depleted Marrow Transplants

  1989cites this paper
• Loss of tolerance associated with disappearance of B cells in a patient sequentially transplanted with paternal and maternal bone marrow for the treatment of severe combined immunodeficiency disease.

  1989cites this paper
• Peripheral tolerance mechanisms prevent the development of autoreactive T cells in chimeras grafted with two minor incompatible thymuses

  1989cites this paper
• Immunological functions in food-restricted rats: enhanced expression of high-affinity interleukin-2 receptors on splenic T cells.

  1989cites this paper
• The synergistic effect of total-lymphoid irradiation with extracted donor alloantigen in inducing transplantation unresponsiveness.

  1989cites this paper
• Use of regression analysis and the complement-dependent cytotoxicity typing assay for predicting lymphoid chimerism.

  1988cites this paper
• Tolerance of engrafted donor T cells following bone marrow transplantation for severe combined immunodeficiency.

  1988cites this paper
• Separation of rat bone marrow cells by counterflow centrifugal elutriation: a model for studying the effects of lymphocyte depletion.

  1988cites this paper
• Syngeneic Graft-versus-Host Disease: Failure of Self: Non-Self Discrimination

  1988cites this paper
• Recent Advances and Future Directions in Bone Marrow Transplantation

  1988cites this paper
• Suppressor activity in the supernatant of T cell clones derived from chimeric mouse spleen cells.

  1988cites this paper
• Non-specific suppressor cells in murine bone marrow chimeras: their possible role in GVHD-associated immunodeficiency.

  1988cites this paper
• SPECIFIC TOLERANCE AND IMMUNOCOMPETENCE IN HAPLOIDENTICAL, BUT NOT IN COMPLETELY ALLOGENEIC, CANINE CHIMERAS TREATED WITH METHOTREXATE AND CYCLOSPORINE

  1987cites this paper
• Suppressor T cells in allogeneic bone marrow chimeras.

  1987cites this paper
• A class II antigen-specific T cell clone can suppress graft-versus-host reactivity in murine allogeneic bone marrow chimeras.

  1987cites this paper
• Human marrow transplantation: an immunological perspective.

  1987cites this paper
• Biology and genetics of hybrid resistance.

  1987cites this paper
• Characterization studies of suppressor cells in murine bone marrow chimaeras.

  1987cites this paper
• Suppressor mechanisms active in the control of graft-v-host disease.

  1987cites this paper
• Properties of Suppressor Cells Induced to Acetylcholine Receptor Using Cyclosporin A a

  1987cites this paper
• Soluble factors secreted by naturally occurring suppressor cells that interfere with in vivo graft‐vs.‐host disease and with T cell responsiveness in vitro

  1987cites this paper
• MANIPULATION OF GRAFT‐VERSUS‐HOST DISEASE FOR A GRAFT‐VERSUS‐LEUKEMIA EFFECT AFTER ALLOGENEIC BONE MARROW TRANSPLANTATION IN AKR MICE WITH SPONTANEOUS LEUKEMIA/LYMPHOMA1

  1986cites this paper
• DEVELOPMENT OF SUPPRESSOR LYMPHOCYTES DURING ACUTE REJECTION OF RAT CARDIAC ALLOGRAFTS AND PRESERVATION OF SUPPRESSION BY ANTI‐IL-2‐RECEPTOR MONOCLONAL ANTIBODY

  1986cites this paper
• Suppressor cells detected in murine bone marrow chimeras.

  1986cites this paper
• Reconstitution of in vitro humoral immune function in bone marrow transplant recipients.

  1986cites this paper
• Treatment with cyclophosphamide reverses acquired resistance to collagen arthritis subsequent to recovery from passive arthritis.

  1986cites this paper
• Studies on mechanisms of acute rejection of vascularized organ allografts.

  1986cites this paper
• Specific suppressor T cells in rats active in the afferent phase of contact hypersensitivity.

  1986cites this paper
• The activity of suppressor cells in the spleen of murine bone marrow chimeras.

  1986cites this paper
• Acute and chronic graft-versus-host disease in man.

  1986cites this paper
• Functional clonal deletion versus suppressor cell-induced transplantation tolerance in chimeras prepared with a short course of total-lymphoid irradiation.

  1986cites this paper
• Treatment and prevention of acute graft-versus-host disease with thalidomide in a rat model.

  1986cites this paper
• Acute host responses to organ allografts

  1986cites this paper
• Methoxsalen and ultraviolet A radiation in treatment of chronic cutaneous graft-versus-host reaction.

  1985cites this paper
• Graft‐versus‐Host‐Reactions: The History that never Was, and the Way Things Happened to Happen

  1985cites this paper
• TRANSPLANTATION TOLERANCE MEDIATED BY SUPPRESSOR T CELLS AND SUPPRESSIVE ANTIBODY IN A RECIPIENT OF A RENAL TRANSPLANT

  1985cites this paper
• Cloned natural suppressor cell lines derived from the spleens of neonatal mice

  1985cites this paper
• Graft‐versus‐Host Reactions and Disease

  1985cites this paper
• THE EFFECT OF LIMITED COURSES OF CYCLOSPORINE ON SURVIVAL AND IMMUNOCOMPETENCE OF ALLOGENEIC BONE MARROW CHIMERAS1

  1985cites this paper
• The effect of class I and class II alloantigens on skin allograft acceptance by lethally irradiated rats repopulated with syngeneic bone marrow.

  1985cites this paper
• Graft-vs.-host reactions: mechanisms and contemporary theories.

  1985cites this paper
• Functional clonal deletion versus active suppression in transplantation tolerance induced by total-lymphoid irradiation.

  1985cites this paper
• Tinea versicolor: a light and electron microscopic study of hyperpigmented skin.

  1985cites this paper
• Characterization of suppressor T cells in graft-versus-host reactions.

  1985cites this paper
• Allosuppressor and allohelper T cells in acute and chronic graft-vs- host disease. V. F1 mice with secondary chronic GVHD contain F1- reactive allohelper but no allosuppressor T cells

  1984cites this paper
• Predictive factors for acute graft-versus-host disease in patients transplanted with HLA-identical bone marrow.

  1984cites this paper
• ACUTE AND CHRONIC GRAFT-VS.-HOST DISEASE V. Fa Mice with Secondary Chronic GVHD Contain F~-reactive Allohelper but no Allosuppressor T Cells

  1984cites this paper
• The Bone Marrow, our Autonomous Morphostatic “Brain”

  1984cites this paper
• Human and murine cutaneous graft‐versus‐host diseases. Potential models for the study of immunologically mediated skin diseases

  1984cites this paper
• Mechanisms of tolerance in marrow transplantation.

  1984cites this paper
• Graft-versus-host disease: pathophysiological and clinical aspects.

  1984cites this paper
• ACCEPTANCE OF CARDIAC ALLOGRAFTS BY LETHALLY IRRADIATED RATS REPOPULATED WITH SYNGENEIC BONE MARROW: ROLE OF CLASS I AND CLASS II ALLOANTIGENS

  1984cites this paper
• GRAFT-VERSUS-HOS T Pathophysiologic al and Clinical Aspects

  1984cites this paper
• Characterization of a subpopulation in neonatal thymus which suppresses the graft‐vs.‐host reaction

  1983cites this paper
• INDUCTION OF TRANSPLANTATION TOLERANCE IN GUINEA PIGS BY SPLEEN ALLOGRAFTS: III. Transfer of Tolerance to Normal Hosts

  1983cites this paper
• T-T cell interactions in cell-mediated immune responses to major histocompatibility complex antigens.

  1983cites this paper
• IDENTIFICATION OF DONOR‐DERIVED ANTIGEN‐SPECIFIC SUPPRESSOR CELLS IN MURINE BONE MARROW CHIMERAS PREPARED WITH TOTAL‐LYMPHOID IRRADIATON

  1983cites this paper
• Characterization of a subpopulation in neonatal thymus which suppress the graft-vs.-host reaction.

  1983cites this paper
• Transplantation tolerance: Lyt-1+2- helper T cells require a second proliferation signal to overcome Lyt- 1-2+ suppressor T cell activity.

  1983cites this paper
• Graft-versus-host disease in cyclosporin A-treated rats after syngeneic and autologous bone marrow reconstitution

  1983cites this paper
• Allogeneic H-2d leads to H-2b irradiation bone marrow chimeras: a) failure to transfer chimerism adoptively and b) immune reactivity of immunocompetent lymphocytes adoptively transferred to chimeras.

  1983cites this paper
• Allogenic bone marrow transplantation: current status and future directions.

  1983cites this paper
• Graft-versus-host disease: immunobiological aspects.

  1983cites this paper
• 4‐Hydroperoxyclophosphamide: a model for eliminating residual human tumour cells and T‐lymphocytes from the bone marrow graft

  1982cites this paper
• SUPPRESSOR CELLS IN TRANSPLANTATION TOLERANCE: III. THE ROLE OF ANTIGEN IN THE MAINTENANCE OF TRANSPLANTATION TOLERANCE

  1982cites this paper