Serum total IGF-I, free IGF-I, and IGFB-1 levels in an elderly population: relation to cardiovascular risk factors and disease.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Arteriosclerosis, Thrombosis and Vascular Biology

• Publication date

  1998-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1161/01.ATV.18.2.277PMID 9484994
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Paracellular transport of insulin‐like growth factor‐I (IGF‐I) across human umbilical vein endothelial cell monolayers

  1997cited by this paper
• Effect of obesity on total and free insulin-like growth factor (IGF)-1, and their relationship to IGF-binding protein (BP)-1, IGFBP-2, IGFBP-3, insulin, and growth hormone

  1997cited by this paper
• Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidaemia and atherosclerosis.

  1997cited by this paper
• Insulin-like growth factor I diminishes in vivo and in vitro vascular contractility: role of vascular nitric oxide.

  1996cited by this paper
• IGFBP-3 proteolysis by plasmin, thrombin, serum: heparin binding, IGF binding, and structure of fragments.

  1996cited by this paper
• Insulin-like growth factor-1 and angiographically documented coronary artery disease

  1996cited by this paper
• The 21‐residue surfactant peptide (LysLeu4)4Lys(KL4) is a transmembrane α‐helix with a mixed nonpolar/polar surface

  1996cited by this paper
• Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in non-insulin dependent diabetes mellitus (NIDDM).

  1996cited by this paper
• Insulin-like growth factor-I and angiographically documented coronary artery disease.

  1996cited by this paper
• The role of the insulin-like growth factor binding proteins and the IGFBP proteases in modulating IGF action.

  1996cited by this paper
• Insulin-like growth factors and their binding proteins: biological actions.

  1995cited by this paper
• Nitric oxide--biological mediator, modulator and factor of injury: its role in the pathogenesis of atherosclerosis.

  1995cited by this paper
• Free insulin-like growth factors in human obesity.

  1995cited by this paper
• Reproducibility of carotid vessel wall thickness measurements. The Rotterdam Study.

  1994cited by this paper
• Direct demonstration of insulin-like growth factor-I-induced nitric oxide production by endothelial cells.

  1994cited by this paper
• The phosphorylation pattern of insulin-like growth factor-binding protein-1 in normal plasma is different from that in amniotic fluid and changes during pregnancy.

  1994cited by this paper
• Regulation of smooth muscle cell growth by endothelium-derived factors.

  1994cited by this paper
• Localization of insulin-like growth factor I and inhibition of coronary smooth muscle cell growth by somatostatin analogues in human coronary smooth muscle cells. A potential treatment for restenosis?

  1994cited by this paper
• Free insulin‐like growth factors (IGF‐I and IGF‐II) in human serum

  1994influential reference
• Carotid intima-media wall thickness in elderly women with and without atherosclerosis of the abdominal aorta.

  1993cited by this paper
• IGFs: function and clinical importance 5 Therapeutic potential of rhIGF‐I in diabetes and conditions of insulin resistance

  1993cited by this paper
• Insulin-like Growth Factor-Binding Protein-1, A Marker of Insulin Production

  1993influential reference
• Isolated systolic hypertension and vessel wall thickness of the carotid artery. The Rotterdam Elderly Study.

  1993cited by this paper
• Sequestration and secretion of insulin‐like growth factor‐I by bovine aortic endothelial cells

  1993cited by this paper
• Regulation and Function of Insulin-Like Growth Factor-Binding Protein-1

  1993cited by this paper
• The diagnostic performance of computer programs for the interpretation of electrocardiograms.

  1992cited by this paper
• Effects of hypophysectomy on vascular insulin-like growth factor-I gene expression after balloon denudation in rats.

  1992cited by this paper
• Detection of premature atherosclerosis by high-resolution ultrasonography in symptom-free hypopituitary adults.

  1992cited by this paper
• Regulation of insulin-like growth factor-I and its receptor in rat aorta after balloon denudation. Evidence for local bioactivity.

  1992cited by this paper
• Insulin-like Growth Factors: Molecular and Cellular Aspects

  1991cited by this paper
• Insulin‐Like Growth Factor I Gene Expression in Vascular Cells

  1991cited by this paper
• Ultrasound measurement of wall thickness in the carotid artery: fundamental principles and description of a computerized analysing system.

  1991cited by this paper
• [Increased prevalence of osteoporosis and arteriosclerosis in conventionally substituted anterior pituitary insufficiency: need for additional growth hormone substitution?].

  1991cited by this paper
• Determinants of disease and disability in the elderly: The Rotterdam elderly study

  1991cited by this paper
• Phosphorylation of insulin-like growth factor (IGF)-binding protein 1 in cell culture and in vivo: effects on affinity for IGF-I.

  1991cited by this paper
• The insulin-like growth factors: their putative role in atherogenesis.

  1991influential reference
• Insulin Resistance: A Multifaceted Syndrome Responsible for NIDDM, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular Disease

  1991cited by this paper
• Transcapillary permeability and subendothelial distribution of endothelial and amniotic fluid insulin-like growth factor binding proteins in the rat heart.

  1990cited by this paper
• Premature mortality due to cardiovascular disease in hypopituitarism.

  1990cited by this paper
• Methodology of the Modular ECG Analysis System MEANS

  1990cited by this paper
• Insulin-like growth factor I (IGF-I)-binding protein complex is a better mitogen than free IGF-I.

  1989cited by this paper
• Characterization of Induction of Protooncogene c-myc and Cellular Growth in Human Vascular Smooth Muscle Cells by Insulin and IGF-I

  1989cited by this paper
• The 1988 report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure.

  1988cited by this paper
• Insulin, insulin-like growth factors, and vascular endothelium.

  1988cited by this paper
• Impaired growth hormone responses to growth hormone-releasing factor in obesity. A pituitary defect reversed with weight reduction.

  1984cited by this paper
• Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure. A cooperative study.

  1977cited by this paper
• Correlation of Postmortem Anatomic Findings with Electrocardiographic Changes in Patients with Myocardial Infarction: Retrospective Study of Patients with Typical Anterior and Posterior Infarcts

  1977cited by this paper
• Cardiovascular survey methods.

  1969cited by this paper

• Inverse association of insulin-like growth factor binding protein 1 with epicardial and intrathoracic adiposity in older adults: The Longenity study.

  2026cites this paper
• IGFBP-1 and IGF-I in relation to adiposity and mortality from midlife to old age in the Swedish Adoption/Twin Study of Aging

  2025influential citation
• Impacts of systemic milieu on cerebrovascular and brain aging: insights from heterochronic parabiosis, blood exchange, and plasma transfer experiments

  2025cites this paper
• The positive impact of smoking on poor sleep quality is moderated by IGF1 levels in cerebrospinal fluid: a case-control study among Chinese adults

  2024cites this paper
• A Nonlinear Relation between Body Mass Index and Long-Term Poststroke Functional Outcome—The Importance of Insulin Resistance, Inflammation, and Insulin-like Growth Factor-Binding Protein-1

  2024cites this paper
• Effect of surgical intervention on serum insulin-like growth factor 1 in patients with obstructive sleep apnoea

  2023influential citation
• Detection rate of IGF-1 variants and their implication to protein binding: study of over 240,000 patients

  2023cites this paper
• The Impact of Westernization on the Insulin/IGF-I Signaling Pathway and the Metabolic Syndrome: It Is Time for Change

  2023cites this paper
• New insights on the cardiovascular effects of IGF-1

  2023cites this paper
• Convergence of Signaling Pathways in Mediating Actions of Leucine and IGF-1 on mTORC1 in L6 Myoblasts.

  2022cites this paper
• INFLUENCE OF INSULIN-LIKE GROWTH FACTOR-I LEVELS ON THE COURSE OF ACUTE MYOCARDIAL INFARCTION: review

  2022cites this paper
• Association of Adult Height with Cardiovascular Mortality: A Systematic Review and Meta-Analysis of Cohort Studies

  2022cites this paper
• Th1, Th2 and Th17 inflammatory pathways synergistically predict cardiometabolic protein expression in serum of COVID-19 patients.

  2022cites this paper
• PM2.5 exposure exaggerates the risk of adverse birth outcomes in pregnant women with pre-existing hyperlipidemia: Modulation role of adipokines and lipidome.

  2021cites this paper
• Proton pump inhibitors are associated with incident type 2 diabetes mellitus in a prospective population‐based cohort study

  2021cites this paper
• IGF-1 is not related to long-term outcome in hyperglycemic acute coronary syndrome patients

  2021cites this paper
• Titrating Growth Hormone Dose to High-Normal IGF-1 Levels Has Beneficial Effects on Body Fat Distribution and Microcirculatory Function Despite Causing Insulin Resistance

  2021cites this paper
• Insulin-Like Growth Factor-1 (IGF-1) and Its Monitoring in Medical Diagnostic and in Sports

  2021cites this paper
• Bifunctional supramolecular nanofiber inhibits atherosclerosis by enhancing plaque stability and anti-inflammation in apoE-/- mice

  2020cites this paper
• A comprehensive contribution of genetic variations of the insulin-like growth factor 1 signalling pathway to stroke susceptibility.

  2020cites this paper
• Does insulin-like growth factor influence prognosis ten months after myocardial infarction?

  2020cites this paper
• IGF-1 and cardiometabolic diseases: a Mendelian randomisation study

  2020cites this paper
• Effects of IGF-1 on the cardiovascular system.

  2019cites this paper
• IGF1 Treatment Improves Cardiac Remodeling after Infarction by Targeting Myeloid Cells.

  2019cites this paper
• Role of IGFBP1 in the senescence of vascular endothelial cells and severity of aging-related coronary atherosclerosis

  2019cites this paper
• Impact of exercise training on dipeptidyl peptidase 4 and insulin-like growth factor binding protein 1 in patients with coronary artery disease: Relationship to nitric oxide response

  2019cites this paper
• The associations of anthropometric, behavioural and sociodemographic factors with circulating concentrations of IGF‐I, IGF‐II, IGFBP‐1, IGFBP‐2 and IGFBP‐3 in a pooled analysis of 16,024 men from 22 studies

  2019cites this paper
• Current Perspectives on Insulin-like Growth Factor Binding Protein (IGFBP) Research

  2019cites this paper
• (2019). The associations of anthropometric, behavioural and sociodemographic factors with circulating concentrations of IGF-I, IGF-II, IGFBP-1, IGFBP-2, and IGFBP-3 in a pooled analysis of 16,024 men from 22 studies. International Journal of Cancer , 145 (12), 3244-3256.

  2019cites this paper
• PAPP-A and the IGF system in Atherosclerosis - What's Up, What's Down?

  2019cites this paper
• Free IGF-1, Intact IGFBP-4, and PicoPAPP-A are Altered in Acute Myocardial Infarction Compared to Stable Coronary Artery Disease and Healthy Controls

  2018cites this paper
• In silico interaction of insulin-like growth factor binding protein 3 with insulin-like growth factor 1

  2018cites this paper
• Current IGFBP-Related Biomarker Research in Cardiovascular Disease—We Need More Structural and Functional Information in Clinical Studies

  2018cites this paper
• Inflammation-Accelerated Senescence and the Cardiovascular System: Mechanisms and Perspectives

  2018cites this paper
• Alterations of IGF-1, complement C3 and superoxide dismutase in patients with moderate-to-severe obstructive sleep apnea hypopnea syndrome.

  2018cites this paper
• Der Effekt von Wachstumshormon auf die menschlichen Alterungsprozesse. Teil 1

  2018cites this paper
• Association of Circulating IGFBP1 Level with the Severity of Coronary Artery Lesions in Patients with Unstable Angina

  2017cites this paper
• Association of IGF-1 with coronary collateral circulation in stable coronary artery disease.

  2017cites this paper
• The association between adult attained height and sitting height with mortality in the European Prospective Investigation into Cancer and Nutrition (EPIC)

  2017cites this paper
• Serum Insulin-Like Growth Factor 1 and the Risk of Ischemic Stroke: The Framingham Study

  2017cites this paper
• Insulin‐like growth factor axis targeting in cancer and tumour angiogenesis – the missing link

  2017cites this paper
• Association of Maternal and Cord Blood IGF-I with Leptin Levels in Preeclampsia

  2016cites this paper
• Atheroprotective Properties of Serum IGF-1 in the Carotid and Coronary Territories and Beneficial Role on the Physical Fitness of the Oldest Old.

  2016cites this paper
• Attenuated IGF-1 predicts all-cause and cardiovascular mortality in a Black population: A five-year prospective study

  2016cites this paper
• Serum insulin-like growth factor-1 , metabolic syndrome and incident cardiovascular disease in older people : a population-based study

  2016cites this paper
• Human placental growth hormone is increased in maternal serum at 20 weeks of gestation in pregnancies with large-for-gestational-age babies

  2016cites this paper
• Efeito da cirurgia bariátrica sobre parâmetros clínicos, laboratoriais e fatores de risco cardiovascular

  2016cites this paper
• Relationship of IGF-1 and cardiac remodeling in overweight patients

  2016cites this paper
• Impact of adult growth hormone deficiency on metabolic profile and cardiovascular risk [Review].

  2015cites this paper
• Early Growth Response protein 1 (Egr-1) expression by Insulin-like growth factor 1 (IGF-1) involves MAPKs and PKB pathways

  2015cites this paper
• Genetic Regulation of Female Sexual Maturation and Longevity Through Circulating IGF1.

  2015cites this paper
• Intrauterine growth restriction perturbs nucleosome depletion at a growth hormone responsive

  2015cites this paper
• Intrauterine growth restriction perturbs nucleosome depletion at a growth hormone-responsive element in the mouse IGF-1 gene X

  2015cites this paper
• Intrauterine growth restriction perturbs nucleosome depletion at a growth hormone-responsive element in the mouse IGF-1 gene.

  2015cites this paper
• Effect of continuous positive airway pressure on insulin growth factor-1 in patients with obstructive sleep apnea: a meta-analysis.

  2015cites this paper
• Гормон роста и инсулиноподобный фактор роста-1 в прогнозе течения ИБС у пациентов с ожирением Growth hormone and insulin-like growth factor-1 in prognosis coronary artery disease in patients with obesity

  2015cites this paper
• Increase in tendon protein synthesis in response to insulin-like growth factor-I is preserved in elderly men.

  2014cites this paper
• Biomarkers of Cardiovascular Aging

  2014cites this paper
• Гормон роста и инсулиноподобный фактор роста-1 в прогнозе течения ИБС у пациентов с ожирением

  2014cites this paper
• Insulin-like growth factor 1, liver enzymes, and insulin resistance in patients with PCOS and hirsutism.

  2014cites this paper
• Both low and high serum IGF-1 levels associate with increased risk of cardiovascular events in elderly men.

  2014cites this paper
• Compromised bioavailable IGF-1 of black men relates favourably to ambulatory blood pressure: The SABPA study.

  2014cites this paper
• Growth hormone and insulin-like growth factor-1 in prognosis coronary artery disease in patients with obesity

  2014cites this paper
• Genes for Exceptional Longevity

  2014cites this paper
• Limited utility of adipokine levels in the diagnosis of malnutrition in the elderly

  2014cites this paper
• Acute myocardial infarction in Kabuki syndrome: chance occurrence or a novel risk factor for premature atherosclerosis?

  2014cites this paper
• IGF-I and IGFBP2 in peripheral artery disease: results of a prospective study

  2014cites this paper
• From THE DEPARTMENT OF MOLECULAR MEDICINE AND SURGERY Karolinska Institutet, Stockholm, Sweden THE HPA AXIS IN TYPE 2 DIABETES SOME ASPECTS IN RELATION TO INSULIN SENSITIVITY, BETA-CELL FUNCTION AND IGF-I/IGFBP-1

  2014cites this paper
• Role of insulin-like growth factor 1 in stent thrombosis under effective dual antiplatelet therapy

  2014cites this paper
• Interaction between insulin-like growth factor-1 and atherosclerosis and vascular aging.

  2014cites this paper
• Vitamin D modulates the association of circulating insulin-like growth factor-1 with carotid artery intima-media thickness.

  2014cites this paper
• Proinsulin and IGFBP-1 predicts mortality in an elderly population.

  2014cites this paper
• A polymorphism at IGF1 locus is associated with carotid intima media thickness and endothelium-dependent vasodilatation.

  2014cites this paper
• Serum IGF 1 , metabolic syndrome , and incident cardiovascular disease in older people : a population-based study

  2013cites this paper
• Uptodate on GH/IGF-1 axis actions

  2013cites this paper
• Serum IGF1, metabolic syndrome, and incident cardiovascular disease in older people: a population-based study.

  2013cites this paper
• The Impact of IGF‐I Gene Polymorphisms on Coronary Artery Disease Susceptibility

  2013cites this paper
• Assessment of serum IGF-1 and adipokines related to metabolic dysfunction in HIV-infected adults.

  2013cites this paper
• The association of insulin-like growth factor-1 with severity of coronary artery disease

  2013cites this paper
• Bootcamp During Neoadjuvant Chemotherapy for Breast Cancer: A Randomized Pilot Trial

  2012cites this paper
• Effects of oral and transdermal estrogen on IGF1, IGFBP3, IGFBP1, serum lipids, and glucose in patients with hypopituitarism during GH treatment: a randomized study.

  2012cites this paper
• Effects of bench step exercise on arterial stiffness in post-menopausal women: contribution of IGF-1 bioactivity and nitric oxide production.

  2012cites this paper
• Low circulating IGF-I bioactivity is associated with human longevity: Findings in centenarians’ offspring

  2012cites this paper
• Hormone replacement therapy and physical function in healthy older men. Time to talk hormones?

  2012cites this paper
• [Psychological and social impact of online gambling].

  2012cites this paper
• Cardiovascular Disease in Older people: A Population-Based Study

  2012cites this paper
• Insulin-like growth factor binding protein-1 in insulin resistance and cardiovascular disease

  2012cites this paper
• Insulin and insulin-like growth factor-I: two of a kind in the development of cardiovascular disease?

  2012cites this paper
• The Contribution of Impaired Mitochondrial Autophagy to Cardiac Aging : Mechanisms and Therapeutic Opportunities

  2012cites this paper
• The insulin-like growth factor-1 gene is associated with cerebral infarction in Japanese subjects.

  2012cites this paper
• Atherosclerotic Risk Factors and Premature Atherosclerosis in Acromegaly Before and After 48 Months of Octreotide-LAR Treatment

  2012cites this paper
• [Is there a relationship between the growth hormone dose and tumoral or cardiovascular complications?].

  2012cites this paper
• Aging, atherosclerosis, and IGF-1.

  2012cites this paper
• Existe-t-il une relation entre la dose d'hormone de croissance et d'éventuelles complications tumorales ou cardiovasculaires ?

  2012cites this paper
• Dosage et interprétation de l’Insulin-Like Growth Factor I (IGF-I) en exploration endocrinienne

  2012cites this paper
• Système IGF, carrefour de diverses pathologies

  2012cites this paper
• Special Issue on Controversies and Progress in IGF-1 and Aging Aging, Atherosclerosis, and IGF-1

  2012cites this paper
• Pre-treatment levels of circulating free IGF-1 identify NSCLC patients who derive clinical benefit from figitumumab

  2012cites this paper
• Growth Factors, Nutrient Signaling, and Cardiovascular Aging

  2012cites this paper
• Serum concentrations of human insulin-like growth factor-1 and levels of insulin-like growth factor-binding protein-5 in patients with nonalcoholic fatty liver disease: association with liver histology

  2012cites this paper