Potential Novel Uses of Thalidomide

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Drugs

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.2165/00003495-200060020-00003
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Oxford Textbook of Palliative Medicine

  2011cited by this paper
• Treatment of cancer pain.

  2011cited by this paper
• CHROMOSOME ABERRATIONS IN HUMAN CELLS INDUCED BY THALIDOMIDE IN VITRO: PRELIMINARY REPORT.

  2009cited by this paper
• Der Nachweis von Contergan und Doriden, insbesondere im Leichenmaterial

  2004cited by this paper
• Marklose nervenfasern im Senium und im Spätstadium der Thalidomid-Polyneuropathie: quantitativ-elektronenmikroskopische Untersuchungen

  2004cited by this paper
• Hinweise auf zentralnervöse Schäden im Rahmen der Thalidomid-Embryopathie

  2004cited by this paper
• Continuous low dose Thalidomide: a phase II study in advanced melanoma, renal cell, ovarian and breast cancer

  2000cited by this paper
• THALIDOMIDE FOR THE TREATMENT OF ORAL APHTHOUS ULCERS IN PATIENTS WITH HUMAN IMMUNODEFICIENCY VIRUS INFECTION

  2000influential reference
• Thalidomide for night sweats in patients with advanced cancer

  2000cited by this paper
• Thalidomide in patients with cachexia due to terminal cancer: preliminary report.

  1999influential reference
• Nature of the Retrograde Signal from Injured Nerves that Induces Interleukin-6 mRNA in Neurons

  1999cited by this paper
• Antitumor activity of thalidomide in refractory multiple myeloma.

  1999cited by this paper
• Thalidomide--a revival story.

  1999cited by this paper
• The role of thalidomide in the treatment of refractory chronic graft-versus-host disease following bone marrow transplantation in children

  1998cited by this paper
• Thalidomide inhibits corneal angiogenesis induced by vascular endothelial growth factor

  1998influential reference
• Does Thalidomide Cause Second Generation Birth Defects?

  1998cited by this paper
• Pentoxifylline decreases in vivo and in vitro tumour necrosis factor‐alpha (TNF‐α) production in lepromatous leprosy patients with erythema nodosum leprosum (ENL)

  1998cited by this paper
• Effectiveness of megestrol acetate in patients with advanced cancer: a randomized, double-blind, crossover study.

  1998cited by this paper
• Randomised comparison of thalidomide versus placebo in toxic epidermal necrolysis.

  1998cited by this paper
• Thalidomide Costimulates Primary Human T Lymphocytes, Preferentially Inducing Proliferation, Cytokine Production, and Cytotoxic Responses in the CD8+ Subset

  1998influential reference
• The effect of thalidomide treatment on vascular pathology and hyperalgesia caused by chronic constriction injury of rat nerve

  1998cited by this paper
• Suppression of serum tumour necrosis factor-alpha by thalidomide does not lead to reversal of tumour vascular collapse and anti-tumour activity of 5,6-dimethylxanthenone-4-acetic acid.

  1998cited by this paper
• Thalidomide Prolongs Experimental Autoimmune Neuritis in Lewis Rats

  1998influential reference
• Differential regulation by thalidomide and dexamethasone of cytokine expression in human peripheral blood mononuclear cells.

  1998influential reference
• A Review of the Drug Treatment of Cachexia Associated with Cancer

  1998cited by this paper
• Role of IL-6 and TNF in thermoregulation and survival during sepsis in mice.

  1998influential reference
• Inhibition of angiogenesis by thalidomide requires metabolic activation, which is species-dependent.

  1998cited by this paper
• Thalidomide for distressing night sweats in advanced malignant disease

  1998cited by this paper
• Effects of thalidomide on neutrophil respiratory burst, chemotaxis, and transmigration of cytokine- and endotoxin-activated endothelium

  1997cited by this paper
• Effect of cytokine modulation by thalidomide on the granulomatous response in murine tuberculosis.

  1997influential reference
• Differential modulation of short and long latency sensory responses in the SI cortex by IL‐6

  1997cited by this paper
• Hydrolysis of thalidomide abrogates its ability to enhance mononuclear cell synthesis of IL-2 as well as its ability to suppress the synthesis of TNF-alpha.

  1997cited by this paper
• Thalidomide is not a mutagen

  1997cited by this paper
• The Metabolic and Immunologic Effects of Short-Term Thalidomide Treatment of Patients Infected with the Human Immunodeficiency Virus

  1997influential reference
• Inhibition of IL-12 production by thalidomide.

  1997influential reference
• Neurotrophins and their receptors in nerve injury and repair.

  1997cited by this paper
• Activity‐dependent conduction latency changes in Aβ fibers of neuropathic rats

  1997cited by this paper
• Thalidomide for the treatment of oral aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group.

  1997cited by this paper
• Paradoxical effect of thalidomide prophylaxis on chronic graft-vs.-host disease.

  1996influential reference
• An open study of pentoxyfylline and thalidomide as adjuvant therapy in the treatment of rheumatoid arthritis.

  1996influential reference
• The effect of thalidomide on the pathogenesis of human immunodeficiency virus type 1 and M. tuberculosis infection.

  1996cited by this paper
• Rapid discontinuation of hypnotics in terminal cancer patients: a prospective study.

  1996cited by this paper
• The effect of thalidomide on experimental tumors and metastases

  1996cited by this paper
• Thalidomide prolonged graft survival in a rat cardiac transplant model but had no inhibitory effect on lymphocyte function in vitro.

  1996influential reference
• Failure of thalidomide to inhibit tumor growth and angiogenesis in vivo.

  1996cited by this paper
• Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α

  1996cited by this paper
• Quantification of interleukin-6 mRNA in wallerian degeneration by competitive reverse transcription polymerase chain reaction.

  1996cited by this paper
• Inhibition of lipolysis and muscle protein degradation by EPA in cancer cachexia.

  1996cited by this paper
• Involvement of human interleukin 6 in experimental cachexia induced by a human uterine cervical carcinoma xenograft.

  1996influential reference
• Interleukin-6-Mediated Hyperalgesia/Allodynia and Increased Spinal IL-6 Expression in a Rat Mononeuropathy Model

  1996cited by this paper
• Interleukin-6 mRNA expression by cortical neurons in culture: evidence for neuronal sources of interleukin-6 production in the brain.

  1995cited by this paper
• The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation.

  1995cited by this paper
• Pentoxifylline for treatment of cancer anorexia and cachexia? A randomized, double-blind, placebo-controlled trial.

  1995cited by this paper
• Involvement of human interleukin 6 in experimental cachexia induced by a human uterine cervical carcinoma xenograft.

  1995cited by this paper
• Thalidomide increases the synthesis of IL-2 in cultures of human mononuclear cells stimulated with Concanavalin-A, Staphylococcal enterotoxin A, and purified protein derivative.

  1995influential reference
• Immunomodulation by thalidomide: systematic review of the literature and of unpublished observations.

  1995cited by this paper
• The immunosuppressive drug thalidomide induces T helper cell type 2 (Th2) and concomitantly inhibits Th1 cytokine production in mitogen‐ and antigen‐stimulated human peripheral blood mononuclear cell cultures

  1995cited by this paper
• Does thalidomide affect IL-2 response and production?

  1995cited by this paper
• Thalidomide and the immune system. 3. Simultaneous up- and down-regulation of different integrin receptors on human white blood cells.

  1994cited by this paper
• Oxford Textbook of Palliative Medicine

  1994cited by this paper
• Thalidomide is an inhibitor of angiogenesis.

  1994influential reference
• The influence of thalidomide on the clinical and immunologic manifestation of erythema nodosum leprosum.

  1993influential reference
• Emptying and refilling of Ca2+ store in tracheal myocytes as indicated by ACh-evoked currents and contraction.

  1993cited by this paper
• Interleukin-8 modulates feeding by direct action in the central nervous system.

  1993cited by this paper
• Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation

  1993influential reference
• Clenbuterol, a beta-adrenoceptor agonist, increases relative muscle strength in orthopaedic patients.

  1993cited by this paper
• Thalidomide and the immune system. 2. Changes in receptors on blood cells of a healthy volunteer.

  1992cited by this paper
• Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes

  1991influential reference
• Thalidomide treatment for chronic graft‐versus‐host disease

  1991cited by this paper
• [Mouth and pharyngeal hyperalgesic syndromes in AIDS].

  1990cited by this paper
• Mast cells as a source of both preformed and immunologically inducible TNF-α/cachectin

  1990cited by this paper
• Mast cells as a source of both preformed and immunologically inducible TNF-alpha/cachectin.

  1990cited by this paper
• The Edmonton staging system for cancer pain: preliminary report

  1989cited by this paper
• Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins.

  1989cited by this paper
• Treatment of refractory rheumatoid arthritis--the thalidomide experience.

  1989cited by this paper
• Thalidomide. A promising new treatment for rheumatoid arthritis.

  1984cited by this paper
• Maple-syrup-urine disease.

  1984cited by this paper
• [Treatment of aphthosis with thalidomide and with colchicine].

  1984cited by this paper
• Demonstration of circulating leukocytic pyrogen/interleukin-1 during fever.

  1984cited by this paper
• Traitement de l’aphtose par la thalidomide et la colchicine

  1984cited by this paper
• Improved control of chemotherapy-induced emesis by the addition of dexamethasone to metoclopramide in patients resistant to metoclopramide.

  1983cited by this paper
• [Thalidomide in the treatment of aphthosis and Behçet's disease. 4 years' experience].

  1982cited by this paper
• Molecular basis of fever in humans.

  1982cited by this paper
• Inhibition of de Novo IgM Antibody Synthesis by Thalidomide as a Relevant Mechanism of Action in Leprosy

  1981cited by this paper
• [Unmyelinated nerve fibers in senile nerves and in late thalidomide neuropathy: a quantitative electron microscopic study (author's transl)].

  1977cited by this paper
• [Genital malformations in thalidomide-damaged girls (author's transl)].

  1976cited by this paper
• Corticosteroid therapy of preterminal gastrointestinal cancer

  1974cited by this paper
• WHO co-ordinated short-term double-blind trial with thalidomide in the treatment of acute lepra reactions in male lepromatous patients.

  1971influential reference
• Thalidomide in the treatment of lepra reactions.

  1971influential reference
• An internally-controlled double blind trial of thalidomide in severe erythema nodosum leprosum.

  1971influential reference
• Codeine and its alternates for pain and cough relief.

  1969cited by this paper
• Codeine and its alternates for pain and cough relief. 2. Alternates for pain relief.

  1969cited by this paper
• Drug responses in man.

  1968cited by this paper
• [Clinical pharmacology].

  1968influential reference
• Ciba Foundation Symposium - Drug Responses in Man

  1967cited by this paper
• Thalidomide in Rabbit Semen

  1967cited by this paper
• [Reference to central nervous system damage within the context of thalidomide embryopathy. Pathological-anatomic, electroencephalographic and neurologic findings].

  1966influential reference
• [Thalidomide in acute symptoms in leprosy (erythema nodosum or multiforme)].

  1966influential reference
• Another chance for thalidomide?

  1966cited by this paper
• Minor ocular abnormalities associated with thalidomide.

  1966cited by this paper

• A drug repositioning success: The repositioned therapeutic applications and mechanisms of action of thalidomide

  2020cites this paper
• Thalidomide with blockade of co-stimulatory molecules prolongs the survival of alloantigen-primed mice with cardiac allografts

  2020cites this paper
• Case of bullous pyoderma gangrenosum in a child

  2018cites this paper
• Critical Aspects of Integrated Nonclinical Drug Development

  2017cites this paper
• TRATAMIENTO DEL MIELOMA: UN MODELO BASADO EN LA BIOLOGÍA CELULAR

  2016cites this paper
• TNFR:Fc construct in dorsal vagal complex LPS-induced suppression of gastric motility relieved by

  2016cites this paper
• Thalidomide in Dermatology: Revisited

  2015cites this paper
• Malignant causes of fever of unknown origin.

  2015cites this paper
• Einfluß vonThalidomid auf die Atherogenese im Tiermodell derApoE-/-/LDL-/ – Doppel- Knockout Maus

  2012cites this paper
• La piel en el contexto de la medicina y sus especialidadesPioderma gangrenosoPyoderma gangrenosum

  2012cites this paper
• Theoretical Basis for the Activity of Thalidomide

  2012cites this paper
• New thalidomide analogues derived through Sonogashira or Suzuki reactions and their TNF expression inhibition profiles.

  2010cites this paper