A noncatalytic function of the ligation complex during nonhomologous end joining

Jessica Cottarel,P. Frit,Oriane Bombarde,B. Salles,Aurélie Négrel,Stéphanie Bernard,P. Jeggo,M. Lieber,M. Modesti,P. Calsou

Published 2013 in Journal of Cell Biology

ABSTRACT

Ligase IV, but not its catalytic function, is required for DNA-PK–dependent end synapsis during nonhomologous end joining.

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