The use of immunohistochemistry in the differential diagnosis of tumors of the testis and paratestis.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Seminars in diagnostic pathology

• Publication date

  2005-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1053/J.SEMDP.2005.11.003PMID 16512598
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Immunohistochemical Profile of Malignant Mesotheliomas of the Tunica Vaginalis: A Study of 20 Cases

  2006cited by this paper
• Extranodal natural killer/T‐cell lymphoma, nasal type

  2006cited by this paper
• Clear cell carcinoma of the urinary bladder.

  2006cited by this paper
• Seminoma With Tubular, Microcystic, and Related Patterns: A Study of 28 Cases of Unusual Morphologic Variants That Often Cause Confusion With Yolk Sac Tumor

  2005cited by this paper
• Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours

  2005cited by this paper
• Primary extramedullary plasmacytoma and multiple myeloma: phenotypic differences revealed by immunohistochemical analysis

  2005cited by this paper
• KIT and RCC Are Useful in Distinguishing Chromophobe Renal Cell Carcinoma From the Granular Variant of Clear Cell Renal Cell Carcinoma

  2005cited by this paper
• Malignant mesothelioma of the tunica vaginalis.

  2005cited by this paper
• Immunoreactivity of CD10 and inhibin alpha in differentiating hemangioblastoma of central nervous system from metastatic clear cell renal cell carcinoma

  2005cited by this paper
• Kidney-specific cadherin, a specific marker for the distal portion of the nephron and related renal neoplasms

  2005cited by this paper
• Selected other problematic testicular and paratesticular lesions: rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumors

  2005cited by this paper
• Diagnostic value of OCT3/4 for pre‐invasive and invasive testicular germ cell tumours

  2005cited by this paper
• Nasal-type extranodal natural killer/T-cell lymphomas: a clinicopathologic and genotypic study of 42 cases in Singapore

  2004cited by this paper
• Malignant mesothelioma of the tunica vaginalis testis: A case with a predominant sarcomatous component

  2004cited by this paper
• WT1 is of value in ascertaining the site of origin of serous carcinomas within the female genital tract.

  2004cited by this paper
• Testicular lymphoma A Retrospective, Population-based, Clinical and Immunohistochemical Study

  2004cited by this paper
• Infarcted Adenomatoid Tumor: A Report of Five Cases of a Facet of a Benign Neoplasm That May Cause Diagnostic Difficulty

  2004cited by this paper
• Non-Leydig sex-cord tumors of the testis. The place of immunohistochemistry in diagnosis and prognosis. A study of twenty cases

  2004cited by this paper
• OCT4: A sensitive and specific biomarker for intratubular germ cell neoplasia of the testis.

  2004cited by this paper
• Endocrine GEP-cells in primary testicular teratoma

  2004cited by this paper
• Establishing a germ cell origin for metastatic tumors using OCT4 immunohistochemistry

  2004cited by this paper
• OCT4 Staining in Testicular Tumors: A Sensitive and Specific Marker for Seminoma and Embryonal Carcinoma

  2004cited by this paper
• Adenomatoid Tumors of the Female and Male Genital Tracts Express WT1

  2004cited by this paper
• Potential Utility of Uroplakin III, Thrombomodulin, High Molecular Weight Cytokeratin, and Cytokeratin 20 in Noninvasive, Invasive, and Metastatic Urothelial (Transitional Cell) Carcinomas

  2003cited by this paper
• Sinonasal Tract and Nasopharyngeal Melanomas: A Clinicopathologic Study of 115 Cases With a Proposed Staging System

  2003cited by this paper
• Neuroendocrine carcinomas (carcinoid tumor) of the testis. A clinicopathologic and immunohistochemical study of ten cases.

  2003cited by this paper
• POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumors.

  2003cited by this paper
• Primary Mucinous Tumors of the Testis and Paratestis: A Report of Nine Cases

  2003cited by this paper
• Immunohistochemical assessment of a testicular tumor in a 63-year-old patient: proposal for an integrated clinicopathologic approach.

  2003cited by this paper
• Cdx2 Protein Expression in Normal and Malignant Human Tissues: An Immunohistochemical Survey Using Tissue Microarrays

  2003cited by this paper
• Malignant large cell calcifying Sertoli cell tumor of the testis.

  2003cited by this paper
• Calretinin expression in human normal and neoplastic tissues: a tissue microarray analysis on 5233 tissue samples.

  2003cited by this paper
• CDX2, a Highly Sensitive and Specific Marker of Adenocarcinomas of Intestinal Origin: An Immunohistochemical Survey of 476 Primary and Metastatic Carcinomas

  2003cited by this paper
• Adenomatous hyperplasia of the rete testis. A review and report of new cases.

  2003cited by this paper
• Primary NK/T Cell Lymphoma of the Testis

  2003cited by this paper
• Leydig Cell Tumors of the Testis With Unusual Features: Adipose Differentiation, Calcification With Ossification, and Spindle-Shaped Tumor Cells

  2002cited by this paper
• Malignant mesothelioma of tunica vaginalis testis: a fatal case with liver metastasis.

  2002cited by this paper
• Clear Cell Carcinoma of the Urinary Bladder: A Report and Comparison of Four Tumors of Mullerian Origin and Nine of Probable Urothelial Origin With Discussion of Histogenesis and Diagnostic Problems

  2002cited by this paper
• Prostate carcinoma with testicular or penile metastases

  2002cited by this paper
• Calretinin, a More Sensitive but Less Specific Marker Than &agr;-Inhibin for Ovarian Sex Cord-Stromal Neoplasms: An Immunohistochemical Study of 215 Cases

  2002cited by this paper
• Intratubular germ cell neoplasia of the testis: testicular intraepithelial neoplasia.

  2002cited by this paper
• Detection and Diagnostic Utilization of Placental Alkaline Phosphatase in Muscular Tissue and Tumors With Myogenic Differentiation

  2002cited by this paper
• CD30 and CD117 (c-kit) Used in Combination Are Useful for Distinguishing Embryonal Carcinoma from Seminoma

  2002cited by this paper
• Malignant Sertoli Cell Tumors of the Testis: A Study of 13 Examples of a Neoplasm Frequently Misinterpreted as Seminoma

  2002cited by this paper
• Utility of immunostaining for S-100 protein subunits in gonadal sex cord-stromal tumors, with emphasis on the large-cell calcifying Sertoli cell tumor of the testis.

  2002cited by this paper
• Desmoplastic small round cell tumor of the paratesticular region

  2002cited by this paper
• p53: A Good Diagnostic Marker for Intratubular Germ Cell Neoplasia, Unclassified

  2001cited by this paper
• Leiomyosarcoma of the Paratesticular Region: A Clinicopathologic Study

  2001cited by this paper
• Renal Cell Carcinoma Metastatic to the Testis and Its Adnexa: A Report of Five Cases Including Three That Accounted for the Initial Clinical Presentation

  2001cited by this paper
• Loss of CD30 expression in metastatic embryonal carcinoma: the effects of chemotherapy?

  2001cited by this paper
• Expression of Calretinin in Human Ovary, Testis, and Ovarian Sex Cord-Stromal Tumors

  2001cited by this paper
• Canalicular Immunostaining of Neprilysin (CD10) as a Diagnostic Marker for Hepatocellular Carcinomas

  2001cited by this paper
• Sertoli Cell Proliferations of the Infantile Testis: An Intratubular Form of Sertoli Cell Tumor?

  2001cited by this paper
• Diagnosing Primary and Metastatic Renal Cell Carcinoma: The Use of the Monoclonal Antibody `Renal Cell Carcinoma Marker'

  2001cited by this paper
• Serous Borderline Tumor of the Paratestis: A Report of Seven Cases

  2001cited by this paper
• Reactivity of Germ Cell Maturation Stage-Specific Markers in Spermatocytic Seminoma: Diagnostic and Etiological Implications

  2001cited by this paper
• p53: a good diagnostic marker for intratubular germ cell neoplasia, unclassified.

  2001cited by this paper
• Inhibin-α, CD99, HEA125, PLAP, and chromogranin immunoreactivity in testicular neoplasms and the androgen insensitivity syndrome

  2000cited by this paper
• Anti‐mesothelial markers in sarcomatoid mesothelioma and other spindle cell neoplasms

  2000cited by this paper
• Immunohistochemical Spectrum of GISTs at Different Sites and Their Differential Diagnosis with a Reference to CD117 (KIT)

  2000cited by this paper
• Inhibin-alpha CD99, HEA125, PLAP, and chromogranin immunoreactivity in testicular neoplasms and the androgen insensitivity syndrome.

  2000cited by this paper
• Use of antibodies to RCC and CD10 in the differential diagnosis of renal neoplasms.

  2000cited by this paper
• Immunohistochemical evidence for mesothelial origin of paratesticular adenomatoid tumour

  2000cited by this paper
• Sex cord-stromal tumors of the testis with entrapped germ cells: a lesion mimicking unclassified mixed germ cell sex cord-stromal tumors.

  2000cited by this paper
• Hepatoid variant of yolk sac tumor of the testis

  2000cited by this paper
• Cytokeratin 7 and Cytokeratin 20 Expression in Epithelial Neoplasms: A Survey of 435 Cases

  2000cited by this paper
• Neuroendocrine carcinomas (carcinoid tumor) of the thymus. A clinicopathologic analysis of 80 cases.

  2000cited by this paper
• Expression of the CD30 antigen in non‐lymphoid tissues and cells

  2000cited by this paper
• Cytokeratin expression in seminoma of the human testis.

  2000cited by this paper
• Primary melanocytic neoplasms of the central nervous systems.

  1999cited by this paper
• Primary melanocytic neoplasms of the central nervous system

  1999cited by this paper
• Germ cell tumors of the mediastinum and testis: a comparative immunohistochemical study of 120 cases.

  1999cited by this paper
• Malignant large cell calcifying Sertoli cell tumor of the testis (LCCSCTT). Report of a case in an elderly man and review of the literature.

  1999cited by this paper
• Ber-H2 (CD30) immunohistochemical staining in malignant melanoma.

  1999cited by this paper
• Spermatocytic seminoma as compared to classical seminoma: An immunohistochemical and DNA flow cytometric study

  1999cited by this paper
• Large cell calcifying Sertoli cell tumor of the testis: a clinicopathological, immunohistochemical, and ultrastructural study of two cases.

  1999cited by this paper
• Microcystic Leydig cell tumors mimicking yolk sac tumor: a report of four cases.

  1999cited by this paper
• Metastatic renal cell carcinoma to the bladder: a clinicopathologic and immunohistochemical study.

  1999cited by this paper
• Ber-H2 (CD30) immunohistochemical staining in malignant melanoma.

  1999cited by this paper
• Metastatic malignant melanoma resembling malignant peripheral nerve sheath tumor: report of 16 cases.

  1999cited by this paper
• Sertoli cell tumors of the testis, not otherwise specified: a clinicopathologic analysis of 60 cases.

  1998cited by this paper
• Malignant mesothelioma of the tunica vaginalis testis

  1998cited by this paper
• A103: An anti-melan-a monoclonal antibody for the detection of malignant melanoma in paraffin-embedded tissues.

  1998cited by this paper
• Immunohistochemical study of testicular sex cord-stromal tumors, including staining with anti-inhibin antibody.

  1998cited by this paper
• Müllerian inhibiting substance, alpha-inhibin, and CD99 expression in sex cord-stromal tumors and endometrioid ovarian carcinomas resembling sex cord-stromal tumors.

  1998cited by this paper
• Inhibin A is a sensitive and specific marker for testicular sex cord-stromal tumors.

  1998cited by this paper
• Localization of the cellular expression of inhibin in trophoblastic tissue

  1998cited by this paper
• Germ cell tumors of the mediastinum and testis: A comparative immunohistochemical study of 120 cases

  1998cited by this paper
• Tyrosinase, melan-A, and KBA62 as markers for the immunohistochemical identification of metastatic amelanotic melanomas on paraffin sections.

  1998cited by this paper
• Immunoreactivity for A103, an antibody to melan-A (Mart-1), in adrenocortical and other steroid tumors.

  1998cited by this paper
• CD99, keratin, and vimentin staining of sex cord-stromal tumors, normal ovary, and testis.

  1998cited by this paper
• Paraffin section detection of the c-kit gene product (CD117) in human tissues: value in the diagnosis of mast cell disorders.

  1998cited by this paper
• Utilization of hepatocyte-specific antibody in the immunocytochemical evaluation of liver tumors.

  1997cited by this paper
• Value of thrombomodulin immunostaining in the diagnosis of transitional cell carcinoma: a comparative study with carcinoembryonic antigen

  1997cited by this paper
• Large cell calcifying Sertoli cell tumor of the testis: contrasting features of six malignant and six benign tumors and a review of the literature.

  1997cited by this paper
• Testicular and epididymal plasmacytoma: a report of 7 cases, including three that were the initial manifestation of plasma cell myeloma.

  1997cited by this paper
• Small cell osteosarcoma of bone

  1997cited by this paper
• Immunohistochemistry of unclassified sex cord-stromal tumors of the testis with a predominance of spindle cells.

  1997cited by this paper
• The prepubertal testis (prenatal and postnatal): its relationship to intratubular germ cell neoplasia: a combined Pediatric Oncology Group and Children's Cancer Study Group.

  1997cited by this paper
• Value of inhibin in the identification of granulosa cell tumors of the ovary.

  1997cited by this paper

• An unusual path to diagnosis: Sertoli cell neoplasia revealing Peutz-Jeghers syndrome in an 8-year-old boy

  2025cites this paper
• Nonseminomatous mixed germ cell tumor of the testis: Case report

  2025cites this paper
• First pediatric case of spermatic cord fibrolipoma: case report and literature review

  2025cites this paper
• Advances in non‐germ cell tumours of the testis: focus on new molecular developments in sex cord‐stromal tumours

  2025cites this paper
• Testicular tumors in commercial boars with infertility: A gross, histologic, and immunohistochemical study

  2024cites this paper
• FoxA2 is a reliable marker for the diagnosis of yolk sac tumour postpubertal‐type

  2023cites this paper
• Intra-Abdominal Testicular Seminoma In A Phenotypic Female: A Case of XY, Disorder of Sex Development Complicated with Seminoma

  2023cites this paper
• Pure testicular choriocarcinoma, a rare and highly malignant subtype with challenging treatment: A case report and review of the literature

  2023cites this paper
• Overcoming Chemotherapy Resistance in Germ Cell Tumors

  2022cites this paper
• Diagnostic and prognostic impact of Cytokeratin 19 expression analysis in human tumors: A tissue microarray study of 13,172 tumors.

  2021cites this paper
• The core four - A panel of immunohistochemistry markers to diagnose and subtype testicular germ cell tumors

  2021cites this paper
• Immunohistochemical Characterization of 120 Testicular Sex Cord-Stromal Tumors With an Emphasis on the Diagnostic Utility of SOX9, FOXL2, and SF-1

  2021cites this paper
• Typical histological pattern of seminoma and its immunoreactivity: A diagnostic challenge

  2021cites this paper
• Testotoxicosis without Testicular Mass: Revealed by Peripheral Precocious Puberty and Confirmed by Somatic LHCGR Gene Mutation

  2020cites this paper
• An Algorithmic Immunohistochemical Approach to Define Tumor Type and Assign Site of Origin

  2020cites this paper
• Diagnostic and prognostic impact of cytokeratin 18 expression in human tumors: a tissue microarray study on 11,952 tumors

  2020cites this paper
• Immunohistochemistry of Cancers

  2020cites this paper
• The potential of brentuximab vedotin, alone or in combination with current clinical therapies, in the treatment of testicular germ cell tumors.

  2019cites this paper
• Anaplastic Lymphoma Kinase Immunocytochemistry in Fine Needle Aspiration Diagnosis of Anaplastic Large-cell Lymphoma

  2018cites this paper
• Protocol for the Examination of Biopsy Specimens From Patients With Extragonadal Germ Cell Tumors

  2018cites this paper
• Therapeutic approaches for refractory germ cell cancer

  2018cites this paper
• Immunohistochemical Pitfalls in Genitourinary Pathology: 2018 Update

  2018cites this paper
• The Clinical Significance of a Small Component of Choriocarcinoma in Testicular Mixed Germ Cell Tumor (MGCT)

  2018cites this paper
• Mediastinal Germ Cell Tumors

  2017cites this paper
• Fatal haemorrhage and neoplastic thrombosis in a captive African lion (Panthera leo) with metastatic testicular sex cord–stromal tumour

  2017influential citation
• Germ Cell Tumors of Infancy and Childhood

  2016cites this paper
• Chapter 137 – Testicular Dysgenesis Syndrome, Cryptorchidism, Hypospadias, and Testicular Tumors∗

  2016cites this paper
• Diffuse type testicular seminoma in a stallion

  2016cites this paper
• The utility of CDX2, GATA3, and DOG1 in the diagnosis of testicular neoplasms: an immunohistochemical study of 109 cases.

  2016cites this paper
• Comprehensive Immunophenotypic Characterization of Adult and Fetal Testes, the Excretory Duct System, and Testicular and Epididymal Appendages

  2016cites this paper
• Investigational targeted therapies for the treatment of testicular germ cell tumors

  2016cites this paper
• Perspectives in Pediatric Pathology, Chapter 25. Testicular and Paratesticular Tumors in the Pediatric Age Group

  2016cites this paper
• Molecular and Immunohistochemical Markers of Diagnostic and Prognostic Value in Testicular Tumors

  2015cites this paper
• Testis and Paratesticular Tissues

  2015cites this paper
• C-Kit And Bcl-2 Expression In Testicular Cancer

  2015cites this paper
• Immunohistochemical study of mixed germ cell sex cord stromal tumours in 13 canine testes.

  2015cites this paper
• Ovarian interstitial cell tumour in a Mongolian gerbil (Meriones unguiculatus)

  2015cites this paper
• Handling and reporting of orchidectomy specimens with testicular cancer: areas of consensus and variation among 25 experts and 225 European pathologists

  2015cites this paper
• The incidence and histological characteristics of intratubular germ cell neoplasia in postpubertal cryptorchid testis

  2015cites this paper
• Sclerosing Sertoli Cell Tumor of the Testis: A Clinicopathologic Study of 20 Cases

  2014cites this paper
• Canine testicular tumors: two types of seminomas can be differentiated by immunohistochemistry

  2014cites this paper
• Clinicopathologic Analysis of Choriocarcinoma as a Pure or Predominant Component of Germ Cell Tumor of the Testis

  2014cites this paper
• Testicular adrenal rest tumors in a patient with congenital adrenal hyperplasia.

  2014cites this paper
• How our practice of histopathology, especially tumour pathology has changed in the last two decades: reflections from a major referral center in Pakistan.

  2014cites this paper
• The application of immunohistochemical biomarkers in urologic surgical pathology.

  2014cites this paper
• Myoid gonadal stromal tumor: a clinicopathologic study of three cases of a distinctive testicular tumor.

  2014cites this paper
• Testicular Embryonal Carcinoma: A Morphologic Study of 180 Cases Highlighting Unusual and Unemphasized Aspects

  2014cites this paper
• Tumors of the breast and female genital organs

  2014cites this paper
• Evaluation of SF-1 Expression in Testicular Germ Cell Tumors: A Tissue Microarray Study of 127 Cases

  2013cites this paper
• Identification and Characterization of 2 Testicular Germ Cell Markers, Glut3 and CyclinA2

  2013cites this paper
• A Leydig cell tumour in a cat: histological and immunohistochemical findings

  2013cites this paper
• Protocol for the examination of specimens from pediatric and adult patients with extragonadal germ cell tumors.

  2011cites this paper
• Chapter 16 – Immunohistology of the Prostate, Bladder, Kidney, and Testis

  2011cites this paper
• Rete Testis-Associated Nodular Steroid Cell Nests: Description of Putative Pluripotential Testicular Hilus Steroid Cells

  2011cites this paper
• Revisión histogenética de los tumores testiculares germinales

  2011cites this paper
• Alpha-fetoprotein-thymidine kinase-luciferase knockin mice: a novel model for dual modality longitudinal imaging of tumorigenesis in liver.

  2011cites this paper
• Podoplanin, a novel marker for seminoma: A comparison study evaluating immunohistochemical expression of podoplanin and OCT3/4.

  2010cites this paper
• Testicular Tumor Pathology

  2010cites this paper
• Modern Soft Tissue Pathology: MERKEL CELL CARCINOMA AND METASTATIC AND SARCOMATOID CARCINOMAS INVOLVING SOFT TISSUE

  2010cites this paper
• Intratubular germ cell neoplasia of the testis and its associated cancers: the use of novel biomarkers.

  2010cites this paper
• Bile duct-like differentiation in teratoma: a clinicopathologic and immunohistochemical study.

  2010cites this paper
• The Lower Urinary Tract and Male Genital System

  2010cites this paper
• Testis and scrotum

  2010cites this paper
• Tumor testicular del síndrome adrenogenital. A propósito de un caso y diagnóstico intraoperatorio

  2010cites this paper
• Immunhistochemischer Algorithmus zur Diagnostik maligner Keimzelltumoren des Hodens

  2010cites this paper
• The Problematic Testicular Tumor

  2010cites this paper
• Diagnosis of metastatic neoplasms: an immunohistochemical approach.

  2010cites this paper
• Determining Tissue of Origin for Metastatic Cancers: Meta-analysis and Literature Review of Immunohistochemistry Performance

  2010cites this paper
• Benign and Malignant Neoplasms of the Testis and Paratesticular Tissue.

  2009cites this paper
• Testicular mixed germ cell tumors: a morphological and immunohistochemical study using stem cell markers, OCT3/4, SOX2 and GDF3, with emphasis on morphologically difficult-to-classify areas

  2009cites this paper
• Testis and Paratestis Including Spermatic Cord

  2009cites this paper
• Testicular tumors--some new and a few perennial problems.

  2009cites this paper
• Differential expression of SOX2 and SOX17 in testicular germ cell tumors.

  2009cites this paper
• Application of immunohistochemistry to the genitourinary system (prostate, urinary bladder, testis, and kidney).

  2008cites this paper
• Seminoma With Conspicuous Signet Ring Cells: A Rare, Previously Uncharacterized Morphologic Variant

  2008cites this paper
• Proteins affecting rod photoreceptor differentiation in the murine retina: A proteomics approach with emphasis on mTOR

  2008cites this paper
• Ten testicular trapdoors

  2008cites this paper
• Cytologic diagnosis of metastatic seminoma to the prostate and urinary bladder: A case report

  2008cites this paper
• Immunohistochemistry in surgical pathology practice: a current perspective of a simple, powerful, yet complex, tool.

  2008cites this paper
• Application of immunohistochemistry in clinical practice: a review.

  2008cites this paper
• Cytomorphologic examination of anaplastic large cell lymphoma by fine‐needle aspiration cytology

  2007cites this paper
• Histologic and Immunohistochemical Characterization of a Testicular Mixed Germ Cell Sex Cord-Stromal Tumor and a Leydig Cell Tumor in a Dog

  2007cites this paper
• REVISIÓN HISTOGENÉTICA DE LOS TUMORES TESTICULARES GERMINALES

  2007cites this paper
• Case records of the Massachusetts General Hospital. Case 6-2007. A 28-year-old man with a mass in the testis.

  2007cites this paper
• Extragonadal Germ Cell Tumors: A Review With Emphasis on Pathologic Features, Clinical Prognostic Variables, and Differential Diagnostic Considerations

  2007cites this paper
• Gastrointestinal stromal tumors: differential diagnosis.

  2006cites this paper
• REVIEW How Our Practice of Histopathology, Especially Tumour Pathology has Changed in the Last Two Decades: Reflections from a Major Referral Center in Pakistan

  year unknowncites this paper