Hepatitis C: Review of the Epidemiology, Clinical Care, and Continued Challenges in the Direct-Acting Antiviral Era

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Current Epidemiology Reports

• Publication date

  2017-04-20

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s40471-017-0108-xPMID 28785531PMCID PMC5544136
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• HCV reinfection incidence and spontaneous clearance rates in HIV-positive men who have sex with men in Western Europe.

  2017cited by this paper
• Health Disparities in Hepatitis C Screening and Linkage to Care at an Integrated Health System in Southeast Michigan

  2016cited by this paper
• Clinical Care Pathways for Patients With Hepatitis C: Reducing Critical Barriers to Effective Treatment

  2016cited by this paper
• Hepatitis C virus infection in the 1945-1965 birth cohort (baby boomers) in a large urban ED.

  2016cited by this paper
• The Potential Impact of a Hepatitis C Vaccine for People Who Inject Drugs: Is a Vaccine Needed in the Age of Direct-Acting Antivirals?

  2016cited by this paper
• Screening and Evaluation of Hepatitis C Virus Infection in Pregnant Women on Opioid Maintenance Therapy: A Retrospective Cohort Study

  2016cited by this paper
• Daclatasvir combined with sofosbuvir or simeprevir in liver transplant recipients with severe recurrent hepatitis C infection

  2016cited by this paper
• Hepatitis C virus vaccine candidates inducing protective neutralizing antibodies

  2016cited by this paper
• Failure to Test and Identify Perinatally Infected Children Born to Hepatitis C Virus-Infected Women.

  2016cited by this paper
• The history of hepatitis C virus (HCV): Basic research reveals unique features in phylogeny, evolution and the viral life cycle with new perspectives for epidemic control.

  2016cited by this paper
• Access to treatment for hepatitis C virus infection: time to put patients first.

  2016cited by this paper
• Hepatitis C reinfection following treatment induced viral clearance among people who have injected drugs.

  2016cited by this paper
• Identification and Clinical Management of Persons with Chronic Hepatitis C Virus Infection - Cherokee Nation, 2012-2015.

  2016cited by this paper
• Hepatitis C reinfection after sustained virological response.

  2016cited by this paper
• Eighteen‐ to 30‐year‐olds more likely to link to hepatitis C virus care: an opportunity to decrease transmission

  2016cited by this paper
• Integrating Routine HCV Testing in Primary Care: Lessons Learned from Five Federally Qualified Health Centers in Philadelphia, Pennsylvania, 2012–2014

  2016cited by this paper
• Rising Mortality Associated With Hepatitis C Virus in the United States, 2003-2013.

  2016influential reference
• Elbasvir-Grazoprevir to Treat Hepatitis C Virus Infection in Persons Receiving Opioid Agonist Therapy: A Randomized Trial.

  2016cited by this paper
• Impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cirrhosis.

  2016cited by this paper
• High Hepatitis C Infection Rate among Baby Boomers in an Urban Primary Care Clinic: Results from the HepTLC Initiative

  2016cited by this paper
• Results of Hepatitis C Birth-Cohort Testing and Linkage to Care in Selected U.S. Sites, 2012–2014

  2016cited by this paper
• HIV Infection Linked to Injection Use of Oxymorphone in Indiana, 2014-2015.

  2016cited by this paper
• Accessibility to Oral Antiviral Therapy for Patients with Chronic Hepatitis C in the United States

  2016cited by this paper
• Increased Hepatitis C Virus (HCV) Detection in Women of Childbearing Age and Potential Risk for Vertical Transmission - United States and Kentucky, 2011-2014.

  2016cited by this paper
• Racial Disparities in Treatment Rates for Chronic Hepatitis C

  2016cited by this paper
• The Burden of Hepatitis C Infection-Related Liver Fibrosis in the United States.

  2016cited by this paper
• Chronic hepatitis C viral infection subverts vaccine‐induced T‐cell immunity in humans

  2016cited by this paper
• Improving Screening Methods for Hepatitis C Among People Who Inject Drugs: Findings from the HepTLC Initiative, 2012–2014

  2016cited by this paper
• Acute HCV in HIV-Infected MSM: Modes of Acquisition, Liver Fibrosis, and Treatment

  2015cited by this paper
• Incidence of sexually transmitted hepatitis C virus infection in HIV-positive men who have sex with men

  2015cited by this paper
• Simple, Effective, but Out of Reach? Public Health Implications of HCV Drugs.

  2015cited by this paper
• Limited Access to New Hepatitis C Virus Treatment Under State Medicaid Programs

  2015cited by this paper
• Hepatitis C virus treatment as prevention in people who inject drugs: testing the evidence

  2015cited by this paper
• Risk Factors for HCV Acquisition Among HIV-Positive MSM in Belgium

  2015cited by this paper
• The cost-effectiveness, health benefits, and financial costs of new antiviral treatments for hepatitis C virus.

  2015cited by this paper
• Results from a Geographically Focused, Community-Based HCV Screening, Linkage-to-Care and Patient Navigation Program

  2015cited by this paper
• Grazoprevir plus elbasvir in treatment-naive and treatment-experienced patients with hepatitis C virus genotype 1 infection and stage 4-5 chronic kidney disease (the C-SURFER study): a combination phase 3 study.

  2015cited by this paper
• Increased incidence of cancer and cancer-related mortality among persons with chronic hepatitis C infection, 2006-2010.

  2015cited by this paper
• Hepatitis C transmission and treatment as prevention - The role of the injecting network.

  2015cited by this paper
• Hepatitis C virus: why do we need a vaccine to prevent a curable persistent infection?

  2015cited by this paper
• Factors Associated With Hepatitis C Infection Among HIV-Infected Men Who Have Sex With Men With No Reported Injection Drug Use in New York City, 2000–2010

  2015cited by this paper
• Evidence-based interventions to enhance assessment, treatment, and adherence in the chronic Hepatitis C care continuum.

  2015cited by this paper
• The continuum of hepatitis C testing and care

  2015cited by this paper
• Hepatitis C: Issues in Children.

  2015cited by this paper
• Daclatasvir plus Sofosbuvir for HCV in Patients Coinfected with HIV-1.

  2015cited by this paper
• Early Patterns of Sofosbuvir Utilization by State Medicaid Programs.

  2015cited by this paper
• Ledipasvir and Sofosbuvir for HCV in Patients Coinfected with HIV-1.

  2015cited by this paper
• Unrecognized chronic hepatitis C virus infection among baby boomers in the emergency department

  2015cited by this paper
• HCV vertical transmission in pregnancy: New horizons in the era of DAAs

  2015cited by this paper
• Restrictions for Medicaid Reimbursement of Sofosbuvir for the Treatment of Hepatitis C Virus Infection in the United States

  2015cited by this paper
• Recommendations for the management of hepatitis C virus infection among people who inject drugs.

  2015cited by this paper
• Increases in Hepatitis C Virus Infection Related to Injection Drug Use Among Persons Aged ≤30 Years — Kentucky, Tennessee, Virginia, and West Virginia, 2006–2012

  2015cited by this paper
• Therapy of chronic hepatitis C virus infection in the era of direct-acting and host-targeting antiviral agents.

  2014cited by this paper
• Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection.

  2014cited by this paper
• Emerging epidemic of hepatitis C virus infections among young nonurban persons who inject drugs in the United States, 2006-2012.

  2014cited by this paper
• Hepatitis Awareness Month and National Hepatitis Testing Day — May 2014

  2014cited by this paper
• Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis.

  2014cited by this paper
• Challenges to the development of vaccines to hepatitis C virus that elicit neutralizing antibodies

  2014cited by this paper
• Chronic Hepatitis C Virus Infection in the United States, National Health and Nutrition Examination Survey 2003 to 2010

  2014cited by this paper
• Hepatitis B and C in pregnancy: a review and recommendations for care

  2014cited by this paper
• Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection.

  2014cited by this paper
• Vertical Transmission of Hepatitis C Virus: Systematic Review and Meta-analysis

  2014cited by this paper
• Treatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin.

  2014cited by this paper
• Sexual transmission of hepatitis C virus among monogamous heterosexual couples: The HCV partners study

  2013cited by this paper
• Hepatitis C Virus in Pregnancy

  2013cited by this paper
• Hepatitis C virus reinfection incidence and treatment outcome among HIV-positive MSM

  2013cited by this paper
• High Rates of Hepatitis C Virus Reinfection and Spontaneous Clearance of Reinfection in People Who Inject Drugs: A Prospective Cohort Study

  2013cited by this paper
• Hepatitis C virus reinfection following treatment among people who use drugs.

  2013cited by this paper
• Perceptions of drug users regarding Hepatitis C screening and care: a qualitative study

  2013cited by this paper
• Combination Interventions to Prevent HCV Transmission Among People Who Inject Drugs: Modeling the Impact of Antiviral Treatment, Needle and Syringe Programs, and Opiate Substitution Therapy

  2013cited by this paper
• Hepatitis C in the United States.

  2013cited by this paper
• Treatment of hepatitis C virus infection among people who are actively injecting drugs: a systematic review and meta-analysis.

  2013cited by this paper
• Incident hepatitis C virus infection in men who have sex with men: a prospective cohort analysis, 1984-2011.

  2013cited by this paper
• Reducing Risk for Mother-to-Infant Transmission of Hepatitis C Virus: A Systematic Review for the U.S. Preventive Services Task Force

  2013cited by this paper
• Testing for HCV Infection: An Update of Guidance for Clinicians and Laboratorians

  2013cited by this paper
• HCV E1E2-MF59 vaccine in chronic hepatitis C patients treated with PEG-IFNα2a and Ribavirin: a randomized controlled trial

  2013cited by this paper
• Screening for Hepatitis C Virus Infection in Adults: U.S. Preventive Services Task Force Recommendation Statement

  2013cited by this paper
• Recommendations for the management of hepatitis C virus infection among people who inject drugs.

  2013cited by this paper
• Evolving epidemiology of hepatitis C virus in the United States.

  2012cited by this paper
• The natural history of hepatitis C virus infection acquired during childhood

  2012cited by this paper
• Notes from the field : hepatitis C virus infections among young adults--rural Wisconsin, 2010.

  2012cited by this paper
• Recommendations for the identification of chronic hepatitis C virus infection among persons born during 1945-1965.

  2012cited by this paper
• Primary care-based interventions are associated with increases in hepatitis C virus testing for patients at risk.

  2012cited by this paper
• Expected and actual case ascertainment and treatment rates for children infected with hepatitis C in Florida and the United States: epidemiologic evidence from statewide and nationwide surveys.

  2012cited by this paper
• Chronic hepatitis C virus infection increases mortality from hepatic and extrahepatic diseases: a community-based long-term prospective study.

  2012cited by this paper
• NASPGHAN practice guidelines: Diagnosis and management of hepatitis C infection in infants, children, and adolescents.

  2012cited by this paper
• Incident hepatitis C virus infection among US HIV-infected men enrolled in clinical trials.

  2011cited by this paper
• Forecasting the morbidity and mortality associated with prevalent cases of pre-cirrhotic chronic hepatitis C in the United States.

  2011cited by this paper
• Alarming incidence of hepatitis C virus re-infection after treatment of sexually acquired acute hepatitis C virus infection in HIV-infected MSM

  2011cited by this paper
• Mortality in patients with chronic and cleared hepatitis C viral infection: a nationwide cohort study.

  2010cited by this paper
• Barriers to and Facilitators of Hepatitis C Testing, Management, and Treatment Among Current and Former Injecting Drug Users: A Qualitative Exploration

  2010cited by this paper
• Safety and immunogenicity of HCV E1E2 vaccine adjuvanted with MF59 administered to healthy adults.

  2010cited by this paper
• Acute hepatitis C in HIV-infected men who have sex with men: an emerging sexually transmitted infection.

  2010cited by this paper
• Immunogenicity of CIGB‐230, a therapeutic DNA vaccine preparation, in HCV‐chronically infected individuals in a Phase I clinical trial

  2009cited by this paper
• Impact of Hepatitis C Virus Infection on Children and Their Caregivers: Quality of Life, Cognitive, and Emotional Outcomes

  2009cited by this paper
• Liver fibrosis during an outbreak of acute hepatitis C virus infection in HIV-infected men: a prospective cohort study.

  2008cited by this paper
• Estimation of stage‐specific fibrosis progression rates in chronic hepatitis C virus infection: A meta‐analysis and meta‐regression

  2008cited by this paper
• Rates of evolutionary change in viruses: patterns and determinants

  2008cited by this paper
• Acute Hepatitis C: A Systematic Review

  2008cited by this paper
• Use of enhanced surveillance for hepatitis C virus infection to detect a cluster among young injection-drug users--new York, November 2004-April 2007.

  2008cited by this paper

• Prevalence of viral hepatitis A and C in patients with inflammatory bowel disease: a nationwide population-based study in South Korea

  2026cites this paper
• The Dual Role of A20 (TNFAIP3) in Viral Infection: A Context-Dependent Regulator of Immunity and Pathogenesis

  2025cites this paper
• Association of Oncogenic Viral Infections With Cardiovascular Risk and Health Outcomes: A Cross-Sectional Study in South Asian Adults

  2025cites this paper
• Intraluminal gas in deep vein thrombosis associated with Rhodotorula mucilaginosa fungemia and Prevotella intermedia bacteremia: a unique clinical case report and literature overview

  2025cites this paper
• The Gut Microbiome in Enteric Viral Infections: Underlying Mechanisms and Therapeutic Approaches

  2025cites this paper
• Current Hepatitis C Status among People Who Use Drugs in the Republic of Korea

  2025cites this paper
• A Study of the Recurrence of Hepatitis C Virus After Achieving a Sustained Virological Response

  2025cites this paper
• Molecular insights into the purified core protein of hepatitis C virus and the roles of its basic and hydrophobic amino acid clusters.

  2025cites this paper
• Global burden of HBV-related liver disease: Primary liver cancer due to chronic HBV infection increased in over one-third of countries globally from 2000 to 2021.

  2025cites this paper
• Bothropstoxins I and II as potent phospholipase A2 molecules from Bothrops jararacussu to impair Hepatitis C virus infection.

  2025cites this paper
• Cryptococcal Meningitis in an HCV-Positive and IVDU- and HIV-Negative Patient: A Case Report and Literature Review

  2024cites this paper
• The roles of HCV core protein and its binding host factor in virus assembly and release

  2024cites this paper
• Quality Assurance for Hepatitis C Virus Point-of-Care Diagnostics in Sub-Saharan Africa

  2023cites this paper
• NK cell subsets and dysfunction during viral infection: a new avenue for therapeutics?

  2023cites this paper
• Simplified Test-to-Treat Strategy for Hepatitis C in Thailand: The Phetchabun Model.

  2023cites this paper
• The impact of expanded access to direct acting antivirals for Hepatitis C virus on patient outcomes in Canada

  2023cites this paper
• Nurse Practitioner-Led Hepatitis C Virus Education in a Central Valley Opioid Treatment Program

  2023cites this paper
• Chronic HCV infection promotes cytotoxicity in antigen-specific CD8+ T cells regardless of virus specificity

  2023cites this paper
• Target-specificity of different amyrin subunits in impeding HCV influx mechanism inside the human cells considering the quantum tunnel profiles and molecular strings of the CD81 receptor: a combined in silico and in vivo study

  2023cites this paper
• Annual trends of hepatitis C virus infection in Manitoba between 1998 and 2018: A focus on special populations.

  2023cites this paper
• Semantic and population analysis of the genetic targets related to COVID-19 and its association with genes and diseases

  2022cites this paper
• Resource Management through Artificial Intelligence in Screening Programs—Key for the Successful Elimination of Hepatitis C

  2022cites this paper
• Plants to Drugs: A Case Study of Human Papilloma Virus and Traditional Chinese Medicine

  2022cites this paper
• Prescreening with a Rapid Diagnostic Test Followed by a Confirmatory Qualitative Nucleic Acid Test Can Simplify Hepatitis C Diagnosis.

  2022cites this paper
• The HCV Envelope Glycoprotein Down-Modulates NF-κB Signalling and Associates With Stimulation of the Host Endoplasmic Reticulum Stress Pathway

  2022cites this paper
• Prevalence of Chronic Infection by Hepatitis C Virus in Asymptomatic Population With Risk Factors in Cartagena, Colombia

  2022cites this paper
• Taking cues from convalescence to improve vaccines against hepatitis C virus

  2022cites this paper
• 염증성 장질환 환자에서 바이러스 간염

  2022cites this paper
• Investigation of Antiviral Potential of Food Carotenoids and Apocarotenoids against RNA-dependent RNA Polymerase of Hepatitis C Virus

  2022cites this paper
• Hepatitis B and C Co-Infection among HIV-Positive Patients Attending Art at General Hospital Kaltungo, Gombe State, Nigeria

  2022cites this paper
• Maternal Hepatitis B or Hepatitis C Virus Carrier Status is Not a Risk Factor for Long-Term Oncologic Morbidity of the Offspring: A Population-Based Cohort Study

  2021cites this paper
• Harm reduction program and hepatitis C prevalence in people who inject drugs (PWID) in Iran: an updated systematic review and cumulative meta-analysis

  2021cites this paper
• Micro-Elimination: Updated Pathway to Global Elimination of Hepatitis C in Small Communities and Industrial Settings during the COVID 19 Pandemic

  2021cites this paper
• Treatment of Comorbid HIV/HCV

  2021cites this paper
• MicroRNA-122 As A Potential Biomarker for Liver Injury Resulted from Chronic Hepatitis C Infection

  2021cites this paper
• Linkage of resistance-associated substitutions in GT1 sofosbuvir+NS5A inhibitor failures treated with glecaprevir/pibrentasvir.

  2021cites this paper
• A case of disseminated cryptococcus in an immunocompetent individual necessitating ventriculoperitoneal shunt

  2021cites this paper
• Hepatitis C screening, diagnosis, and cascade of care among people aged > 40 years in Brasilia, Brazil

  2020cites this paper
• Defining the hepatitis C cure cascade in an Urban health system using the electronic health record

  2020cites this paper
• Peer to peer communication about hepatitis C treatment amongst people who inject drugs: A longitudinal qualitative study.

  2020cites this paper
• Immune Modulatory Effects of Vitamin D on Viral Infections

  2020cites this paper
• Chronic Hepatitis C Virus Infection is Associated with an Increased Risk of Lung Cancer: A Systematic Review and Meta-analysis

  2020cites this paper
• A systematic review and meta-analysis of the prevalence of hepatitis C virus infection in people who inject drugs in Iran

  2020cites this paper
• Routine screening for HIV, hepatitis B virus and hepatitis C virus in individuals undergoing oral and maxillofacial surgery

  2019cites this paper
• SOFOSBUVIR: TREATMENT OF CHRONIC HEPATITIS C AND THE MAIN TRENDS IN PATENT PROTECTION

  2019cites this paper
• Discovery and Characterization of Potent Pan-Genotypic HCV NS5A Inhibitors Containing Novel Tricyclic Central Core Leading to Clinical Candidate.

  2019cites this paper
• Factors Correlating to the Development of Hepatitis C Virus Infection among Drug Users—Findings from a Systematic Review and Meta-Analysis

  2019cites this paper
• HCV infection causes cirrhosis in human by step-wise regulation of host genes involved in cellular functioning and defense during fibrosis: Identification of bio-markers

  2019cites this paper
• Oral mucosal changes associated with primary diseases in other body systems.

  2019cites this paper
• An Updated Review on the Epidemiology, Pathophysiology, Etiology and Diagnosis of Liver Cirrhosis

  2019cites this paper
• Screening for hepatitis C in a general adult population in a low-prevalence area: the Tromsø study

  2019cites this paper
• Cellular stress response during hepatitis C virus infection : a balancing act between viral persistence and host cell survival

  2018cites this paper
• Update on the management of hepatitis B and C infections in the neonatal period.

  2018cites this paper
• Interleukin-7 Regulates T Follicular Helper Cell Function in Patients with Chronic Hepatitis C

  2018cites this paper
• Pegylated interferon alpha 2a for the treatment of hepatitis C virus infection

  2018cites this paper
• Impact of sustained virological response on the extrahepatic manifestations of chronic hepatitis C: a meta-analysis

  2018cites this paper
• Spleen stiffness mirrors changes in portal hypertension after successful interferon-free therapy in chronic-hepatitis C virus patients

  2018cites this paper
• Pharmacists' increasing involvement in hepatitis C management and prevention.

  2018cites this paper
• Unique Challenges of Hepatitis C in Infants, Children, and Adolescents.

  2018cites this paper
• Hepatitis C Within a Single Health System: Progression Along the Cascade to Cure Is Higher for Those With Substance Misuse When Linked to a Clinic With Embedded Support Services

  2018cites this paper
• World Journal of Virology

  year unknowncites this paper