The Receptor-like Cytoplasmic Kinase BIK1 Localizes to the Nucleus and Regulates Defense Hormone Expression during Plant Innate Immunity.

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Cell Host and Microbe

• Publication date

  2018-04-11

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.chom.2018.03.010PMID 29649442PMCID PMC6266874
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The highly buffered Arabidopsis immune signaling network conceals the functions of its components

  2017influential reference
• Receptor Kinases in Plant-Pathogen Interactions: More Than Pattern Recognition[OPEN]

  2017cited by this paper
• The WRKY57 Transcription Factor Affects the Expression of Jasmonate ZIM-Domain Genes Transcriptionally to Compromise Botrytis cinerea Resistance1

  2016influential reference
• Arabidopsis receptor-like cytoplasmic kinase BIK1: purification, crystallization and X-ray diffraction analysis.

  2016influential reference
• Regulation of pattern recognition receptor signalling in plants

  2016cited by this paper
• Jasmonates: biosynthesis, metabolism, and signaling by proteins activating and repressing transcription

  2016influential reference
• Transcriptional Regulation of Pattern-Triggered Immunity in Plants.

  2016cited by this paper
• Salicylic acid receptors activate jasmonic acid signalling through a non-canonical pathway to promote effector-triggered immunity

  2016cited by this paper
• Disruption of Ethylene Responses by Turnip mosaic virus Mediates Suppression of Plant Defense against the Green Peach Aphid Vector1[OPEN]

  2015cited by this paper
• Transcriptional networks in plant immunity.

  2015cited by this paper
• Tyrosine phosphorylation of protein kinase complex BAK1/BIK1 mediates Arabidopsis innate immunity

  2014influential reference
• Microbe-associated molecular pattern-induced calcium signaling requires the receptor-like cytoplasmic kinases, PBL1 and BIK1

  2014cited by this paper
• The FLS2-associated kinase BIK1 directly phosphorylates the NADPH oxidase RbohD to control plant immunity.

  2014cited by this paper
• Deciphering key features in protein structures with the new ENDscript server

  2014cited by this paper
• Mechanisms underlying robustness and tunability in a plant immune signaling network.

  2014influential reference
• Direct regulation of the NADPH oxidase RBOHD by the PRR-associated kinase BIK1 during plant immunity.

  2014cited by this paper
• Novel Positive Regulatory Role for the SPL6 Transcription Factor in the N TIR-NB-LRR Receptor-Mediated Plant Innate Immunity

  2013cited by this paper
• Structural Basis for flg22-Induced Activation of the Arabidopsis FLS2-BAK1 Immune Complex

  2013cited by this paper
• The Anticipation of Danger: Microbe-Associated Molecular Pattern Perception Enhances AtPep-Triggered Oxidative Burst1[W]

  2013cited by this paper
• Hormonal modulation of plant immunity.

  2012influential reference
• Arabidopsis WRKY33 Is a Key Transcriptional Regulator of Hormonal and Metabolic Responses toward Botrytis cinerea Infection1[W]

  2012influential reference
• Towards automated crystallographic structure refinement with phenix.refine

  2012cited by this paper
• Structural basis for the impact of phosphorylation on the activation of plant receptor-like kinase BAK1

  2012influential reference
• Biochemical and Genetic Requirements for Function of the Immune Response Regulator BOTRYTIS-INDUCED KINASE1 in Plant Growth, Ethylene Signaling, and PAMP-Triggered Immunity in Arabidopsis[C][W]

  2011influential reference
• Hormone crosstalk in plant disease and defense: more than just jasmonate-salicylate antagonism.

  2011influential reference
• Phosphorylation-Dependent Differential Regulation of Plant Growth, Cell Death, and Innate Immunity by the Regulatory Receptor-Like Kinase BAK1

  2011influential reference
• Receptor-like cytoplasmic kinases integrate signaling from multiple plant immune receptors and are targeted by a Pseudomonas syringae effector.

  2010influential reference
• Low Oleic Acid-Derived Repression of Jasmonic Acid-Inducible Defense Responses Requires the WRKY50 and WRKY51 Proteins1[W][OA]

  2010influential reference
• The multifunctional leucine-rich repeat receptor kinase BAK1 is implicated in Arabidopsis development and immunity.

  2010cited by this paper
• Network Properties of Robust Immunity in Plants

  2009influential reference
• Evolutionary History and Stress Regulation of Plant Receptor-Like Kinase/Pelle Genes1[W][OA]

  2009cited by this paper
• A receptor-like cytoplasmic kinase, BIK1, associates with a flagellin receptor complex to initiate plant innate immunity

  2009influential reference
• Towards a reporter system to identify regulators of cross-talk between salicylate and jasmonate signaling pathways in Arabidopsis

  2008cited by this paper
• Epidermal growth factor receptor juxtamembrane region regulates allosteric tyrosine kinase activation

  2007cited by this paper
• Quantitative phosphoproteomic analysis of plasma membrane proteins reveals regulatory mechanisms of plant innate immune responses

  2007cited by this paper
• Regulation of tradeoffs between plant defenses against pathogens with different lifestyles

  2007cited by this paper
• Pathogen-associated molecular pattern recognition rather than development of tissue necrosis contributes to bacterial induction of systemic acquired resistance in Arabidopsis.

  2007cited by this paper
• Isolation of Arabidopsis nuclei and measurement of gene transcription rates using nuclear run-on assays

  2006cited by this paper
• Perception of the bacterial PAMP EF-Tu by the receptor EFR restricts Agrobacterium-mediated transformation.

  2006cited by this paper
• Contrasting mechanisms of defense against biotrophic and necrotrophic pathogens.

  2005cited by this paper
• The Membrane-Anchored BOTRYTIS-INDUCED KINASE1 Plays Distinct Roles in Arabidopsis Resistance to Necrotrophic and Biotrophic Pathogens[W]

  2005influential reference
• Bacterial disease resistance in Arabidopsis through flagellin perception

  2004influential reference
• Coot: model-building tools for molecular graphics.

  2004cited by this paper
• NPR1 Modulates Cross-Talk between Salicylate- and Jasmonate-Dependent Defense Pathways through a Novel Function in the Cytosol Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.009159.

  2003cited by this paper
• Constitutive expression of ETHYLENE-RESPONSE-FACTOR1 in Arabidopsis confers resistance to several necrotrophic fungi.

  2002cited by this paper
• The conformational plasticity of protein kinases.

  2002cited by this paper
• BAK1, an Arabidopsis LRR receptor-like protein kinase, interacts with BRI1 and modulates brassinosteroid signaling.

  2002influential reference
• Faculty Opinions recommendation of BRI1/BAK1, a receptor kinase pair mediating brassinosteroid signaling.

  2002influential reference
• Both the Extracellular Leucine-Rich Repeat Domain and the Kinase Activity of FLS2 Are Required for Flagellin Binding and Signaling in Arabidopsis

  2001cited by this paper
• FLS2: an LRR receptor-like kinase involved in the perception of the bacterial elicitor flagellin in Arabidopsis.

  2000cited by this paper
• Plants have a sensitive perception system for the most conserved domain of bacterial flagellin.

  1999cited by this paper
• Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana.

  1998cited by this paper
• The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

  1995cited by this paper
• Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

  1995cited by this paper
• Protein kinase superfamily — comparisons of sequence data with three-dimensional structures

  1994cited by this paper
• The functional organization of the nopaline A. tumefaciens plasmid pTiC58.

  1980cited by this paper
• Electronic Reprint Biological Crystallography Phenix : a Comprehensive Python-based System for Macromolecular Structure Solution

  year unknowncited by this paper

• Genome-wide identification and functional validation of RLCK VII subfamily genes conferring disease resistance in broad bean (Vicia faba L.)

  2026cites this paper
• Multi-Omics Analysis Identifies the Key Defence Pathways in Chinese Cabbage Responding to Black Spot Disease

  2026cites this paper
• Motif-based substrate mapping of the receptor-like cytoplasmic kinase BIK1 reveals novel components and regulatory nodes of plant immunity

  2026cites this paper
• Screening and Validation of Interacting Proteins of Receptor-like Cytoplasmic Kinase OsRLCK118 Involved in Rice Blast Resistance.

  2026cites this paper
• Pathogenicity factor p22 of tomato chlorosis virus interferes with abscisic acid‐mediated antiviral defenses by disrupting the function of WRKY81 in tomato

  2025cites this paper
• Receptor-like cytoplasmic kinases mediated signaling in plant immunity: convergence and divergence

  2025cites this paper
• Role of Tyrosine Phosphorylation in PEP1 Receptor 1(PEPR1) in Arabidopsis thaliana

  2025cites this paper
• Molecular Dialog of Ralstonia solanacearum and Plant Hosts with Highlights on Type III Effectors

  2025cites this paper
• WRKY Transcription Factors: Epigenetic and Post‐Translational Regulation of Plant Immunity and Growth–Environment Adaptation

  2025cites this paper
• Exogenous BR Enhances Host Resistance to Rhizoctonia solani Through Reactive Oxygen Species Homeostasis and Photosynthesis Improvement in Oryza sativa.

  2025cites this paper
• Unraveling key genes and pathways involved in Verticillium wilt resistance by integrative GWAS and transcriptomic approaches in Upland cotton

  2025cites this paper
• Specific phosphorylation at Ser60 in N terminus of SlCAK1 propels bacterial cold shock protein-induced immunity in Solanaceae plants.

  2025cites this paper
• CERK1-mediated phosphorylation of PBL19 is crucial for antifungal defense in plants

  2025cites this paper
• Deciphering the metabolic patterns of cashew apple ripening process: A comprehensive non-targeted metabolomics analysis

  2025cites this paper
• Climate change effects on plant immune activation.

  2025cites this paper
• Early transcriptomic responses to Fusarium oxysporum in two cabbage cultivars

  2025cites this paper
• Signaling of Plant Defense Mediated by Receptor-like Kinases, Receptor-like Cytoplasmic Protein Kinases and MAPKs Triggered by Fungal Chitin in Horticultural Crops

  2024cites this paper
• Structural Insights into Ligand Recognition and Receptor Activation of Plant Leucine-Rich Repeat (LRR) Transmembrane Receptors

  2024cites this paper
• The Multifaceted Ubiquitination of BIK1 During Plant Immunity in Arabidopsis thaliana

  2024cites this paper
• Plant immune resilience to a changing climate: Molecular insights and biotechnological roadmaps.

  2024cites this paper
• Osmotic signaling releases PP2C-mediated inhibition of Arabidopsis SnRK2s via the receptor-like cytoplasmic kinase BIK1

  2024cites this paper
• The receptor‐like cytoplasmic kinase OsBSK1‐2 regulates immunity via an HLH/bHLH complex

  2024cites this paper
• Engineering a conserved immune coreceptor into a primed state enhances fungal resistance in crops without growth penalty.

  2024cites this paper
• Overexpression of the receptor-like cytoplasmic kinase SZE1 positively regulates the PTI signaling pathway in Arabidopsis

  2024cites this paper
• Synergy in Rice Immunity: Exploring Strategies of Coordinated Disease Defense through Receptor-Like Kinases and Receptor- Like Cytoplasmic Kinases

  2024cites this paper
• Understanding Botrytis cinerea infection and gray mold management: a review paper on deciphering the rose's thorn

  2024cites this paper
• Comparative Transcriptome Analysis of Resistant and Susceptible Genotypes of Isabgol (Plantago ovata) During Interactions with Peronospora plantaginis, the Causal Agent of Downy Mildew Disease

  2024cites this paper
• Melon CmRLCK VII-8 kinase genes CmRLCK27, CmRLCK30 and CmRLCK34 modulate resistance against bacterial and fungal diseases in Arabidopsis.

  2024cites this paper
• STRESS INDUCED FACTOR 2 is a dual regulator for defense and seed germination in Arabidopsis.

  2024cites this paper
• Tomato SlWRKY3 Negatively Regulates Botrytis cinerea Resistance via TPK1b

  2024cites this paper
• Unleashing plant synthetic capacity: navigating regulatory mechanisms for enhanced bioproduction and secondary metabolite discovery.

  2024cites this paper
• Receptor-like cytoplasmic kinases: orchestrating plant cellular communication.

  2024cites this paper
• Pattern-Triggered Immunity and Effector-Triggered Immunity: crosstalk and cooperation of PRR and NLR-mediated plant defense pathways during host–pathogen interactions

  2024cites this paper
• S-nitrosylation of a receptor-like cytoplasmic kinase regulates plant immunity

  2024cites this paper
• Phosphorylation of the alpha-I motif in SYMRK drives root nodule organogenesis

  2024influential citation
• Dissection of the IDA promoter identifies WRKY transcription factors as abscission regulators in Arabidopsis

  2024cites this paper
• Pathogen Perception and Signalling in Plant Immunity.

  2024cites this paper
• Dual phosphorylation of DGK5-mediated PA burst regulates ROS in plant immunity.

  2024cites this paper
• A novel protein elicitor (PeSy1) from Saccharothrix yanglingensis induces plant resistance and interacts with a receptor‐like cytoplasmic kinase in Nicotiana benthamiana

  2023cites this paper
• Structural and biochemical basis of FLS2-mediated signal activation and transduction in rice

  2023cites this paper
• Plant hormones and secondary metabolites under environmental stresses: Enlightening defense molecules.

  2023cites this paper
• Genome-Wide Characterization and Digital Expression Analysis of the TELOMERASE REVERSE TRANSCRIPTASE (TERT) Gene in Arabidopsis thaliana

  2023cites this paper
• Asymmetric Evolution of Protein Domains in the Leucine-Rich Repeat Receptor-Like Kinase Family of Plant Signaling Proteins

  2023cites this paper
• Overlapping Local and Systemic Defense Induced by an Oomycete Fatty Acid MAMP and Brown Seaweed Extract in Tomato

  2023cites this paper
• ERF and WRKY transcription factors regulate IDA and abscission timing in Arabidopsis

  2023cites this paper
• Unraveling the Molecular Mechanisms of Tomatoes’ Defense against Botrytis cinerea: Insights from Transcriptome Analysis of Micro-Tom and Regular Tomato Varieties

  2023cites this paper
• The PTI‐suppressing Avr2 effector from Fusarium oxysporum suppresses mono‐ubiquitination and plasma membrane dissociation of BIK1

  2023cites this paper
• Receptor-like cytoplasmic kinase ScRIPK in sugarcane regulates disease resistance and drought tolerance in Arabidopsis

  2023cites this paper
• Danger-associate peptide regulates root immunity in Arabidopsis.

  2023cites this paper
• The RLCK-VND6 module coordinates secondary cell wall formation and adaptive growth in rice.

  2023cites this paper
• Conservation of land plant-specific receptor-like cytoplasmic kinase subfamily XI possessing a unique kinase insert domain

  2023cites this paper
• Tomato receptor-like cytoplasmic kinase Fir1 interacts with a negative regulator of jasmonic acid signaling

  2023cites this paper
• Conservation of the PBL-RBOH immune module in land plants.

  2023cites this paper
• Sucrose preferentially promotes expression of OsWRKY7 and OsPR10a to enhance defense response to blast fungus in rice

  2023cites this paper
• miRNAs and lncRNAs in tomato: Roles in biotic and abiotic stress responses

  2023cites this paper
• Pathogenic strategies and immune mechanisms to necrotrophs: Differences and similarities to biotrophs and hemibiotrophs.

  2022cites this paper
• Thirty years of resistance: Zig-zag through the plant immune system

  2022cites this paper
• Activation and turnover of the plant immune signaling kinase BIK1: a fine balance.

  2022cites this paper
• Ubiquitin ligase OsRINGzf1 regulates drought resistance by controlling the turnover of OsPIP2;1

  2022cites this paper
• JrWRKY21 interacts with JrPTI5L to activate expression of JrPR5L for resistance to Colletotrichum gloeosporioides in walnut.

  2022cites this paper
• Inactivation of a wheat protein kinase gene confers broad-spectrum resistance to rust fungi.

  2022cites this paper
• Plasma membrane-nucleo-cytoplasmic coordination of a receptor-like cytoplasmic kinase promotes EDS1-dependent plant immunity

  2022cites this paper
• Exogenous expression of barley HvWRKY6 in wheat improves broad-spectrum resistance to leaf rust, Fusarium crown rot, and sharp eyespot.

  2022cites this paper
• Plasma membrane-to-organelle communication in plant stress signaling.

  2022cites this paper
• Overlapping local and systemic defense induced by an oomycete fatty acid MAMP and brown seaweed extract in tomato

  2022cites this paper
• The receptor-like cytoplasmic kinase OsRLCK118 regulates plant development and basal immunity in rice (Oryza sativa L.)

  2022cites this paper
• A surface-receptor-coupled G protein regulates plant immunity through nuclear protein kinases.

  2022cites this paper
• Climate change impedes plant immunity mechanisms

  2022influential citation
• Large-scale analysis of the N-terminal regulatory elements of the kinase domain in plant Receptor-like kinase family

  2022cites this paper
• CHYR1 ubiquitinates the phosphorylated WRKY70 for degradation to balance immunity in Arabidopsis thaliana.

  2021cites this paper
• Biometabolomics of Host Resistance to Hemi-biotrophs and

  2021cites this paper
• Arabidopsis PUB2 and PUB4 connect signaling components of pattern-triggered immunity.

  2021cites this paper
• Untangling the UV-B radiation-induced transcriptional network regulating plant morphogenesis and secondary metabolite production

  2021cites this paper
• Temporal role of the receptor-like cytoplasmic kinase gene Stpk-V in wheat-Blumeria graminis f. sp. tritici interaction by RNA-seq analysis

  2021cites this paper
• The RLK protein TaCRK10 activates wheat high-temperature seedling-plant resistance to stripe rust through interacting with TaH2A.1.

  2021cites this paper
• Molecular mechanisms of early plant pattern-triggered immune signaling.

  2021cites this paper
• Full-Length Transcriptome-Wide Characteristic and Functional Identification of WRKY Family in Malus sieversii during the Valsa Canker Disease Response

  2021influential citation
• Protein Phosphorylation in Plant Cell Signaling.

  2021cites this paper
• More than an on-and-off switch: Post-translational modifications of plant pattern recognition receptor complexes.

  2021cites this paper
• Activation loop phosphorylation of a non-RD receptor kinase initiates plant innate immune signaling

  2021influential citation
• EDS1 signalling: At the nexus of intracellular and surface receptor immunity.

  2021cites this paper
• Ubiquitin signalling: controlling the message of surface immune receptors.

  2021cites this paper
• PTI-ETI crosstalk: an integrative view of plant immunity.

  2021cites this paper
• Differential Ubiquitination of BIK1 Fine-Tunes Plant Immunity.

  2020cites this paper
• Functional analysis of rubber tree receptor-like cytoplasmic kinase HbBIK1 in plant root development and immune response

  2020cites this paper
• Arabidopsis cell surface LRR immune receptor signaling through the EDS1-PAD4-ADR1 node

  2020cites this paper
• Phosphorylation-dependent subfunctionalization of the calcium-dependent protein kinase CPK28

  2020cites this paper
• Unusual DNA-binding properties of the Arabidopsis thaliana WRKY50 transcription factor at target gene promoters

  2020cites this paper
• Ribosomal protein QM/RPL10 positively regulates defence and protein translation mechanisms during nonhost disease resistance

  2020influential citation
• Large-scale identification of ubiquitination sites on membrane-associated proteins in Arabidopsis thaliana seedlings

  2020cites this paper
• A molecular roadmap to the plant immune system

  2020cites this paper
• Dynamic regulation of Pep-induced immunity through post-translational control of defence transcript splicing

  2020cites this paper
• The evolving landscape of cell surface pattern recognition across plant immune networks.

  2020cites this paper
• Ligand-induced BIK1 monoubiquitination regulates plant immunity

  2020cites this paper
• Regulation of reactive oxygen species during plant immunity through phosphorylation and ubiquitination of RBOHD

  2020cites this paper
• A rare gain of function mutation in a wheat tandem kinase confers resistance to powdery mildew

  2020cites this paper
• Tyrosine phosphorylation of the lectin receptor‐like kinase LORE regulates plant immunity

  2020influential citation
• PRR Cross-Talk Jump Starts Plant Immunity.

  2019cites this paper
• WRKY transcription factors: evolution, binding, and action

  2019influential citation
• BRASSINOSTEROID-SIGNALING KINASE5 Associates with Immune Receptors and Is Required for Immune Responses1

  2019cites this paper