foxD5a, a Xenopus winged helix gene, maintains an immature neural ectoderm via transcriptional repression that is dependent on the C-terminal domain.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Developmental Biology

• Publication date

  2001-04-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1006/DBIO.2001.0191PMID 11401404
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2004cited by this paper
• Neuroectodermal specification and regionalization of the Spemann organizer in Xenopus.

  2000cited by this paper
• Unified nomenclature for the winged helix/forkhead transcription factors.

  2000cited by this paper
• Intrinsic Bias and Lineage Restriction in the Phenotype Determination of Dopamine and Neuropeptide Y Amacrine Cells

  2000cited by this paper
• Early development of Xenopus laevis : a laboratory manual

  2000cited by this paper
• Cell lineage and fate determination

  1999cited by this paper
• A novel fork head gene mediates early steps during Xenopus lens formation.

  1999cited by this paper
• Wnt signaling in Xenopus embryos inhibits bmp4 expression and activates neural development.

  1999cited by this paper
• Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.

  1999cited by this paper
• The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals

  1999cited by this paper
• Maternal Signaling Pathways and the Regulation of Cell Fate

  1999cited by this paper
• Gene expression pattern Characterization of a subfamily of related winged helix genes, XFD-12/ 12 0 /12 00 (XFLIP), during Xenopus embryogenesis

  1999cited by this paper
• Wnt signaling and transcriptional control of Siamois in Xenopus embryos.

  1998cited by this paper
• XBF-2 is a transcriptional repressor that converts ectoderm into neural tissue.

  1998cited by this paper
• The globular domain of histone H1 is sufficient to direct specific gene repression in early Xenopus embryos.

  1998cited by this paper
• XBF-1, a winged helix transcription factor with dual activity, has a role in positioning neurogenesis in Xenopus competent ectoderm.

  1998cited by this paper
• fork head domain genes in zebrafish

  1998cited by this paper
• Gene activation during early stages of lens induction in Xenopus.

  1998cited by this paper
• Pre-MBT patterning of early gene regulation in Xenopus: the role of the cortical rotation and mesoderm induction.

  1998cited by this paper
• Xiro3 encodes a Xenopus homolog of the Drosophila Iroquois genes and functions in neural specification

  1998cited by this paper
• From cortical rotation to organizer gene expression: toward a molecular explanation of axis specification in Xenopus

  1998cited by this paper
• Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulation.

  1998cited by this paper
• Analysis of the developing Xenopus tail bud reveals separate phases of gene expression during determination and outgrowth.

  1998cited by this paper
• Direct neural induction and selective inhibition of mesoderm and epidermis inducers by Xnr3.

  1997cited by this paper
• The Rx homeobox gene is essential for vertebrate eye development

  1997cited by this paper
• LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter.

  1997cited by this paper
• Siamois is required for formation of Spemann's organizer.

  1997cited by this paper
• Characterization and early embryonic expression of a neural specific transcription factor xSOX3 in Xenopus laevis.

  1997cited by this paper
• A transcriptional modification motif encoded by homeobox and fork head genes

  1997cited by this paper
• A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus.

  1997cited by this paper
• Revelations of a captive: retroviral Qin and the oncogenicity of winged helix proteins.

  1997cited by this paper
• Transcription factors and induction in Xenopus laevis embryos

  1997cited by this paper
• Short historical survey of pattern formation in the endo-mesoderm and the neural anlage in the vertebrates: the role of vertical and planar inductive actions

  1997cited by this paper
• A role for Siamois in Spemann organizer formation.

  1997cited by this paper
• Neural induction and antero-posterior patterning in the amphibian embryo: past, present and future

  1997cited by this paper
• Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues

  1997cited by this paper
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  1997cited by this paper
• Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.

  1997cited by this paper
• Visualization of cell replication using antibody to proliferating cell nuclear antigen.

  1997cited by this paper
• Evidence that the DNA binding specificity of winged helix proteins is mediated by a structural change in the amino acid sequence adjacent to the principal DNA binding helix.

  1997cited by this paper
• Neural Network Prediction of Translation Initiation Sites in Eukaryotes: Perspectives for EST and Genome Analysis

  1997influential reference
• Formation and function of Spemann's organizer.

  1997cited by this paper
• Avian winged helix proteins CWH-1, CWH-2 and CWH-3 repress transcription from Qin binding sites

  1997cited by this paper
• Induction of the primary dorsalizing center in Xenopus by the Wnt/GSK/beta-catenin signaling pathway, but not by Vg1, Activin or Noggin.

  1997cited by this paper
• Aberrant cell growth induced by avian winged helix proteins.

  1997cited by this paper
• Patterning the Xenopus blastula.

  1997cited by this paper
• The whn transcription factor encoded by the nude locus contains an evolutionarily conserved and functionally indispensable activation domain.

  1996cited by this paper
• Developmental expression of a neuron‐specific β‐tubulin in frog (Xenopus laevis): A marker for growing axons during the embryonic period

  1996cited by this paper
• Identification of neurogenin, a vertebrate neuronal determination gene.

  1996cited by this paper
• A molecular mechanism for the effect of lithium on development.

  1996cited by this paper
• A conserved region of engrailed, shared among all en-, gsc-, Nk1-, Nk2- and msh-class homeoproteins, mediates active transcriptional repression in vivo.

  1996cited by this paper
• Beta-catenin translocation into nuclei demarcates the dorsalizing centers in frog and fish embryos.

  1996cited by this paper
• Copyright � 1997, American Society for Microbiology Hepatocyte Nuclear Factor 3/fork head Homolog 11 Is Expressed in Proliferating Epithelial and Mesenchymal Cells

  1996cited by this paper
• Five years on the wings of fork head.

  1996cited by this paper
• Activation of Siamois by the Wnt pathway.

  1996cited by this paper
• Synergistic effects of Vg1 and Wnt signals in the specification of dorsal mesoderm and endoderm.

  1996cited by this paper
• Genesis, a Winged Helix Transcriptional Repressor with Expression Restricted to Embryonic Stem Cells*

  1996cited by this paper
• Active repression mechanisms of eukaryotic transcription repressors.

  1996cited by this paper
• The homeobox gene Siamois is a target of the Wnt dorsalisation pathway and triggers organiser activity in the absence of mesoderm.

  1996cited by this paper
• A fork head related multigene family is transcribed in Xenopus laevis embryos.

  1996cited by this paper
• Domains of the qin protein required for oncogenic transformation.

  1996cited by this paper
• The vertebrate organizer: structure and molecules.

  1996cited by this paper
• Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein.

  1995cited by this paper
• The oncogene qin codes for a transcriptional repressor.

  1995cited by this paper
• Anterior neurectoderm is progressively induced during gastrulation: the role of the Xenopus homeobox gene orthodenticle.

  1995cited by this paper
• Differential expression of fork head genes during early Xenopus and zebrafish development.

  1995influential reference
• Basic FGF as an inducer of anteroposterior neural pattern.

  1995cited by this paper
• Analysis of hepatocyte nuclear factor-3 beta protein domains required for transcriptional activation and nuclear targeting.

  1995cited by this paper
• DNA recognition site analysis of Xenopus winged helix proteins.

  1995cited by this paper
• Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis.

  1995cited by this paper
• Xwnt-8b: a maternally expressed Xenopus Wnt gene with a potential role in establishing the dorsoventral axis.

  1995cited by this paper
• HNF-3β is essential for node and notochord formation in mouse development

  1994cited by this paper
• Cloning and characterization of the t(X;II) breakpoint from a leukemic cell line identify a new member of the forkhead gene family

  1994cited by this paper
• Novel HOX, POU and FKH genes expressed during bFGF-induced mesodermal differentiation in Xenopus.

  1994cited by this paper
• Spatial and temporal transcription patterns of the forkhead related XFD-2/XFD-2' genes in Xenopus laevis embryos.

  1994cited by this paper
• Expression of winged helix genes, BF-1 and BF-2, define adjacent domains within the developing forebrain and retina.

  1994cited by this paper
• The cleavage stage origin of Spemann's Organizer: analysis of the movements of blastomere clones before and during gastrulation in Xenopus.

  1994cited by this paper
• HNF-3 beta is essential for node and notochord formation in mouse development.

  1994cited by this paper
• CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.

  1994cited by this paper
• New member of the winged-helix protein family disrupted in mouse and rat nude mutations

  1994cited by this paper
• Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes.

  1994cited by this paper
• Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5

  1993cited by this paper
• Cellular and subcellular distribution of HNK‐1 immunoreactivity in the neural tube of Xenopus

  1993cited by this paper
• The structure and expression of the Xenopus Krox-20 gene: conserved and divergent patterns of expression in rhombomeres and neural crest.

  1993cited by this paper
• The retroviral oncogene qin belongs to the transcription factor family that includes the homeotic gene fork head.

  1993cited by this paper
• Developmentally regulated Drosophila gene family encoding the fork head domain.

  1992cited by this paper
• Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis.

  1992cited by this paper
• Telencephalon-restricted expression of BF-1, a new member of the HNF-3/fork head gene family, in the developing rat brain.

  1992cited by this paper
• A novel, activin-inducible, blastopore lip-specific gene of Xenopus laevis contains a fork head DNA-binding domain.

  1992cited by this paper
• Activin A induced expression of a fork head related gene in posterior chordamesoderm (notochord) of Xenopus laevis embryos.

  1992cited by this paper
• Hepatocyte nuclear factor 3 beta contains two transcriptional activation domains, one of which is novel and conserved with the Drosophila fork head protein

  1992cited by this paper
• Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis.

  1992cited by this paper
• Neuronal determination without cell division in Xenopus embryos.

  1991influential reference
• Early embryonic development of Xenopus laevis.

  1991cited by this paper
• Chapter 5 Early Embryonic Development of Xenopus laevis

  1991cited by this paper
• Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head.

  1991cited by this paper
• Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction.

  1991cited by this paper
• Cephalic expression and molecular characterization of Xenopus En-2.

  1991cited by this paper
• Cell rearrangement during gastrulation of Xenopus: direct observation of cultured explants.

  1991cited by this paper
• HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally.

  1990cited by this paper

• Targets of the transcription factor Six1 identify previously unreported candidate deafness genes

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• Reference genome provide insights into sex determination of silver aworana (Osteoglossum bicirrhosum)

  2025cites this paper
• Alcohol induces neural tube defects by reducing retinoic acid signaling and promoting neural plate expansion

  2023cites this paper
• Repressive Interactions Between Transcription Factors Separate Different Embryonic Ectodermal Domains

  2022cites this paper
• Foxd4l1.1 Negatively Regulates Chordin Transcription in Neuroectoderm of Xenopus Gastrula

  2021cites this paper
• Goosecoid Controls Neuroectoderm Specification via Dual Circuits of Direct Repression and Indirect Stimulation in Xenopus Embryos

  2021cites this paper
• Natural size variation among embryos leads to the corresponding scaling in gene expression.

  2020cites this paper
• The transcription factor E2A drives neural differentiation in pluripotent cells

  2020cites this paper
• Foxd4l1.1 negatively regulates transcription of neural repressor ventx1.1 during neuroectoderm formation in Xenopus embryos

  2020cites this paper
• The transcription factor E2A drives neural differentiation in pluripotent cells

  2019cites this paper
• Six1 and Irx1 have reciprocal interactions during cranial placode and otic vesicle formation.

  2019cites this paper
• Uncovering novel regulators of neural fate commitment in embryonic stem cells

  2019influential citation
• Investigating the coordinated transcriptional networksregulating Xenopus myogenesis

  2018cites this paper
• Foxd4 is essential for establishing neural cell fate and for neuronal differentiation

  2017cites this paper
• Wbp2nl has a developmental role in establishing neural and non-neural ectodermal fates.

  2017cites this paper
• Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm

  2016cites this paper
• High-Sensitivity Mass Spectrometry for Probing Gene Translation in Single Embryonic Cells in the Early Frog (Xenopus) Embryo

  2016cites this paper
• Functional analysis of Prdm14 during Xenopus embryogenesis

  2016cites this paper
• Ornithine-δ-Aminotransferase Inhibits Neurogenesis During Xenopus Embryonic Development.

  2015cites this paper
• Early Development of Epidermis and Neural Tissue

  2015cites this paper
• of differentially expressed candidate genes identification exencephaly in mice: genetic analysis and -associated Cecr2 Strain-specific modifier genes of

  2015cites this paper
• Early neural ectodermal genes are activated by siamois and twin during blastula stages

  2015influential citation
• Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression.

  2014cites this paper
• Neural Transcription Factors: from Embryos to Neural Stem Cells

  2014cites this paper
• PV.1 Suppresses the Expression of FoxD5b during Neural Induction in Xenopus Embryos

  2014cites this paper
• Novel animal pole‐enriched maternal mRNAs are preferentially expressed in neural ectoderm

  2014cites this paper
• Conserved Structural Domains in FoxD4L1, a Neural Forkhead Box Transcription Factor, Are Required to Repress or Activate Target Genes

  2013influential citation
• Genetic analysis of the forkhead transcriptional factor 2 gene in three Chinese families with blepharophimosis syndrome

  2013cites this paper
• ERF and ETV3L are retinoic acid-inducible repressors required for primary neurogenesis

  2013cites this paper
• On becoming neural: what the embryo can tell us about differentiating neural stem cells.

  2013influential citation
• Blastomere explants to test for cell fate commitment during embryonic development.

  2013cites this paper
• The FOXL2 mutation (c.402C>G) in adult-type ovarian granulosa cell tumors of three Japanese patients: clinical report and review of the literature.

  2013cites this paper
• AP-1(c-Jun/FosB) mediates xFoxD5b expression in Xenopus early developmental neurogenesis.

  2013cites this paper
• The FOXL 2 Mutation ( c . 402 C > G ) in Adult-Type Ovarian Granulosa Cell Tumors of Three Japanese Patients : Clinical Report and Review of the Literature

  2013cites this paper
• Molecular characterization of Ptf1a activity during Xenopus embryogenesis

  2013influential citation
• Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.

  2012cites this paper
• Specific domains of FoxD4/5 activate and repress neural transcription factor genes to control the progression of immature neural ectoderm to differentiating neural plate.

  2012influential citation
• Auditory progenitor stem cell biology and therapy

  2012cites this paper
• Characterization of flounder (Paralichthys olivaceus) FoxD5 and its function in regulating myogenic regulatory factor

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• The response of early neural genes to FGF signaling or inhibition of BMP indicate the absence of a conserved neural induction module

  2011cites this paper
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  2011cites this paper
• Minireview: roles of the forkhead transcription factor FOXL2 in granulosa cell biology and pathology.

  2011cites this paper
• The evolutionary origin of the vertebrate neural crest and its developmental gene regulatory network--insights from amphioxus.

  2010cites this paper
• The mouse forkhead gene Foxp2 modulates expression of the lung genes.

  2010cites this paper
• Microarray identification of novel downstream targets of FoxD4L1/D5, a critical component of the neural ectodermal transcriptional network

  2010influential citation
• Neural induction and factors that stabilize a neural fate.

  2009cites this paper
• Notch signaling downstream of foxD5 promotes neural ectodermal transcription factors that inhibit neural differentiation

  2009influential citation
• foxD5 plays a critical upstream role in regulating neural ectodermal fate and the onset of neural differentiation.

  2009influential citation
• The regulation and function of SoxB1 genes and proteins during neural induction and development in Xenopus laevis

  2009cites this paper
• Identification of the transcriptional targets of FOXP2, a gene linked to speech and language, in developing human brain.

  2007cites this paper
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  2007cites this paper
• FOXL2 mutations in Chinese patients with blepharophimosis-ptosis-epicanthus inversus syndrome

  2007cites this paper
• FoxD3 and Grg4 Physically Interact to Repress Transcription and Induce Mesoderm in Xenopus*

  2007cites this paper
• Direct activation by Ets and Zic is required for initial expression of the Brachyury gene in the ascidian notochord.

  2007cites this paper
• Prevalence of the EH1 Groucho interaction motif in the metazoan Fox family of transcriptional regulators

  2007cites this paper
• Novel gene ashwin functions in Xenopus cell survival and anteroposterior patterning

  2006cites this paper
• Transcriptional Repressor foxl1 Regulates Central Nervous System Development by Suppressing shh Expression in Zebra Fish

  2006cites this paper
• A new heterozygous mutation of the FOXL2 gene is associated with a large ovarian cyst and ovarian dysfunction in an adolescent girl with blepharophimosis/ptosis/epicanthus inversus syndrome.

  2005cites this paper
• Of Fox and Frogs: Fox (fork head/winged helix) transcription factors in Xenopus development.

  2005cites this paper
• Identification of novel genes affecting mesoderm formation and morphogenesis through an enhanced large scale functional screen in Xenopus.

  2005cites this paper
• A downstream enhancer is essential for Xenopus FoxD5 transcription.

  2004cites this paper
• Forkhead l2 is expressed in the ovary and represses the promoter activity of the steroidogenic acute regulatory gene.

  2004cites this paper
• Xenopus flotillin1, a novel gene highly expressed in the dorsal nervous system

  2004cites this paper
• Isolation and characterization of five Fox (Forkhead) genes from the sponge Suberites domuncula.

  2004cites this paper
• Neural Induction, Neural Fate Stabilization, and Neural Stem Cells

  2002cites this paper
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  2002cites this paper
• Multiple maternal influences on dorsal–ventral fate of Xenopus animal blastomeres

  2002cites this paper
• An amphioxus winged helix/forkhead gene, AmphiFoxD: Insights into vertebrate neural crest evolution

  2002influential citation
• Multiple functions of a Zic-like gene in the differentiation of notochord, central nervous system and muscle in Ciona savignyi embryos.

  2002cites this paper
• An essential role of a FoxD gene in notochord induction in Ciona embryos.

  2002cites this paper