4-Hydroxynonenal affects pRb/E2F pathway in HL-60 human leukemic cells.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2002-07-12

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0006-291X(02)00649-6PMID 12150942
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Histone acetylation and the cell-cycle in cancer.

  2001cited by this paper
• Growth inhibition and differentiation induction in murine erythroleukemia cells by 4-hydroxynonenal

  2001cited by this paper
• Complex Transcriptional Regulatory Mechanisms Control Expression of the E2F3 Locus

  2000cited by this paper
• Primer3 on the WWW for general users and for biologist programmers.

  2000cited by this paper
• Oxidative stress and cell cycle checkpoint function.

  2000cited by this paper
• The Rb/E2F pathway: expanding roles and emerging paradigms.

  2000cited by this paper
• Opposite Functions for E2F1 and E2F4 in Human Epidermal Keratinocyte Differentiation*

  2000cited by this paper
• Changes in E2F binding after phenylbutyrate-induced differentiation of Caco-2 colon cancer cells.

  2000cited by this paper
• Inhibition of D1, D2, and A-cyclin expression in HL-60 cells by the lipid peroxydation product 4-hydroxynonenal.

  1999cited by this paper
• 4-Hydroxynonenal As a Biological Signal: Molecular Basis and Pathophysiological Implications

  1999cited by this paper
• The growth arrest and downregulation of c-myc transcription induced by ceramide are related events dependent on p21 induction, Rb underphosphorylation and E2F sequestering

  1998cited by this paper
• E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription

  1998cited by this paper
• Regulation of the cdk inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F

  1998cited by this paper
• Expression and regulation of G1 cell-cycle inhibitors (p16INK4A , p15INK4B, p18 INK4C, p19INK4D ) in human acute myeloid leukemia and normal myeloid cells

  1997cited by this paper
• The retinoblastoma protein pathway and the restriction point.

  1996cited by this paper
• 4-hydroxynonenal specifically inhibits c-myb but does not affect c-fos expressions in HL-60 cells.

  1996cited by this paper
• Effect of 4-Hydroxynonenal on cell cycle progression and expression of differentiation-associated antigens in HL-60 cells.

  1996cited by this paper
• A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation.

  1996cited by this paper
• Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4.

  1996cited by this paper
• A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo.

  1995cited by this paper
• p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation.

  1995cited by this paper
• A direct role of transcription factor E2F in c-myc gene expression during granulocytic and macrophage-like differentiation of HL60 cells.

  1995cited by this paper
• Expression of the p16 and p15 cyclin-dependent kinase inhibitors in lymphocyte activation and neuronal differentiation.

  1995cited by this paper
• Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53.

  1994cited by this paper
• E2F-dependent regulation of human MYC: trans-activation by cyclins D1 and A overrides tumour suppressor protein functions.

  1994cited by this paper
• Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function.

  1994cited by this paper
• Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age.

  1994cited by this paper
• Inhibition of c-myc expression induced by 4-hydroxynonenal, a product of lipid peroxidation, in the HL-60 human leukemic cell line.

  1994cited by this paper
• A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

  1993cited by this paper
• Structural and functional properties of ribosomal protein L7 from humans and rodents.

  1993cited by this paper
• Monoclonal antibodies to NF‐Y define its function in MHC class II and albumin gene transcription.

  1992cited by this paper
• 4-Hydroxynonenal, a product of cellular lipid peroxidation, which modulates c-myc and globin gene expression in K562 erythroleukemic cells.

  1992cited by this paper
• Retinoblastoma protein switches the E2F site from positive to negative element

  1992cited by this paper
• Identification of a 60-kilodalton Rb-binding protein, RBP60, that allows the Rb-E2F complex to bind DNA

  1992cited by this paper
• E2F: a link between the Rb tumor suppressor protein and viral oncoproteins.

  1992cited by this paper
• Induction of differentiation in human HL-60 cells by 4-hydroxynonenal, a product of lipid peroxidation.

  1991cited by this paper
• Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes.

  1991cited by this paper
• The E2F transcription factor is a cellular target for the RB protein.

  1991cited by this paper
• Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A trans-activation.

  1990cited by this paper
• Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells.

  1989cited by this paper
• Nuclear factor E2F mediates basic transcription and trans-activation by E1a of the human MYC promoter.

  1989cited by this paper
• Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells.

  1985cited by this paper
• Amplification and expression of the c-myc oncogene in human lung cancer cell lines

  1983cited by this paper

• Post-translational inhibition of YAP oncogene expression by 4-hydroxynonenal in bladder cancer cells.

  2019cites this paper
• Transcriptional Factor Modulation by Lipid Peroxidation-Derived Aldehydes

  2019cites this paper
• 4-Hydroxyhexenal and 4-hydroxynonenal are mediators of the anti-cachectic effect of n-3 and n-6 polyunsaturated fatty acids on human lung cancer cells.

  2016cites this paper
• Covalent Modification of CDK2 by 4-Hydroxynonenal as a Mechanism of Inhibition of Cell Cycle Progression.

  2016cites this paper
• [Oxidative stress and its effect on cells functional activity of alzheimer's disease].

  2015cites this paper
• On the role of 4-hydroxynonenal in health and disease.

  2015cites this paper
• Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

  2014cites this paper
• Role of glutathione, glutathione transferase, and glutaredoxin in regulation of redox-dependent processes

  2014cites this paper
• Oxidative stress and its effect on cell functional activity in Alzheimer’s disease

  2014cites this paper
• The inclusion complex of 4-hydroxynonenal with a polymeric derivative of β-cyclodextrin enhances the antitumoral efficacy of the aldehyde in several tumor cell lines and in a three-dimensional human melanoma model.

  2013cites this paper
• Regulation of Signal Transduction by Glutathione Transferases

  2012cites this paper
• Oxidative Stress and Lipid Peroxidation Products in Cancer Progression and Therapy

  2012cites this paper
• Role of 4-hydroxy-trans-2-nonenal in cell functions

  2010cites this paper
• 4-hydroxynonenal, a lipid peroxidation product of dietary polyunsaturated fatty acids, has anticarcinogenic properties in colon carcinoma cell lines through the inhibition of telomerase activity.

  2010cites this paper
• The "Two-Faced" Effects of Reactive Oxygen Species and the Lipid Peroxidation Product 4-Hydroxynonenal in the Hallmarks of Cancer

  2010cites this paper
• MicroRNA expression changes during human leukemic HL-60 cell differentiation induced by 4-hydroxynonenal, a product of lipid peroxidation.

  2009cites this paper
• Down-regulation of Notch1 expression is involved in HL-60 cell growth inhibition induced by 4-hydroxynonenal, a product of lipid peroxidation.

  2008cites this paper
• Lipid peroxidation: control of cell proliferation, cell differentiation and cell death.

  2008cites this paper
• The Role of PPAR Ligands in Controlling Growth-Related Gene Expression and their Interaction with Lipoperoxidation Products

  2008cites this paper
• The c-myc promoter: still MysterY and challenge.

  2008cites this paper
• Trapping of 4-hydroxynonenal by glutathione efficiently prevents formation of DNA adducts in human cells.

  2007cites this paper
• 4-Hydroxynonenal and PPARgamma ligands affect proliferation, differentiation, and apoptosis in colon cancer cells.

  2007cites this paper
• 4-Hydroxynonenal inhibits telomerase activity and hTERT expression in human leukemic cell lines.

  2006cites this paper
• 4‐Hydroxynonenal and cell cycle

  2005cites this paper
• Regulation of 4-hydroxynonenal mediated signaling by glutathione S-transferases.

  2005cites this paper
• Aldehyde Sources, Metabolism, Molecular Toxicity Mechanisms, and Possible Effects on Human Health

  2005cites this paper
• 4-Hydroxynonenal inhibits cell proliferation and alters differentiation pathways in human fetal liver hematopoietic stem cells.

  2005cites this paper
• 4-Hydroxynonenal modulation of p53 family gene expression in the SK-N-BE neuroblastoma cell line.

  2005cites this paper
• Breast cancer cell-targeted oxidative stress: enhancement of cancer cell uptake of conjugated linoleic acid, activation of p53, and inhibition of proliferation.

  2005cites this paper
• CARACTERISATION D'UN NOUVEL ALDEHYDE D'ORIGINE PLAQUETTAIRE (4-HYDROXYDODECADIENAL) ET FORMATION D'ADDUITS DE MICHAEL AVEC LES PHOSPHOLIPIDES A ETHANOLAMINE

  2004cites this paper
• 4-hydroxynonenal and regulation of cell cycle: effects on the pRb/E2F pathway.

  2004cites this paper
• Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases.

  2004cites this paper
• 4-hydroxynonenal from pathology to physiology.

  2003cites this paper