Role of Extracellular RNA in Atherosclerotic Plaque Formation in Mice

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Circulation

• Publication date

  2014-02-04

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1161/CIRCULATIONAHA.113.002562PMID 24201302PMCID PMC3946546
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Legionella Kinase LegK2 Targets the ARP2/3 Complex To Inhibit Actin Nucleation on Phagosomes and Allow Bacterial Evasion of the Late Endocytic Pathway

  2015cited by this paper
• Letter by Chen et al regarding article, "Role of extracellular RNA in atherosclerotic plaque formation in mice".

  2014cited by this paper
• Role of Extracellular RNA and TLR3‐Trif Signaling in Myocardial Ischemia–Reperfusion Injury

  2014cited by this paper
• Extracellular nucleic acids as novel alarm signals in the vascular system

  2013cited by this paper
• CD14-Dependent Monocyte Isolation Enhances Phagocytosis of Listeria monocytogenes by Proinflammatory, GM-CSF-Derived Macrophages

  2013cited by this paper
• Extrazelluläre Nukleinsäuren als neue Alarmsignale des vaskulären Systems – Mediatoren bei Abwehr und Krankheit

  2013cited by this paper
• Transcriptional control of macrophage polarization.

  2013cited by this paper
• Extracellular RNA liberates tumor necrosis factor-α to promote tumor cell trafficking and progression.

  2013cited by this paper
• Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells

  2012cited by this paper
• Extracellular RNA promotes leukocyte recruitment in the vascular system by mobilising proinflammatory cytokines

  2012influential reference
• Atherosclerosis: current pathogenesis and therapeutic options

  2011cited by this paper
• Vascular inflammation and repair: implications for re-endothelialization, restenosis, and stent thrombosis.

  2011cited by this paper
• Interleukin‐10 overexpression in macrophages suppresses atherosclerosis in hyperlipidemic mice

  2010cited by this paper
• Expression and localisation of vascular ribonucleases in endothelial cells

  2010cited by this paper
• Integrative Physiology/Experimental Medicine Importance of Junctional Adhesion Molecule-C for Neointimal Hyperplasia and Monocyte Recruitment in Atherosclerosis-Prone Mice–Brief Report

  2009cited by this paper
• Interleukin-10 Facilitates Both Cholesterol Uptake and Efflux in Macrophages*

  2009cited by this paper
• Signaling mechanism of extracellular RNA in endothelial cells

  2009cited by this paper
• RNase therapy assessed by magnetic resonance imaging reduces cerebral edema and infarction size in acute stroke.

  2009cited by this paper
• C1-Esterase Inhibitor Protects Against Neointima Formation After Arterial Injury in Atherosclerosis-Prone Mice

  2008influential reference
• Extracellular RNA constitutes a natural procoagulant cofactor in blood coagulation

  2007cited by this paper
• Vascular endothelial growth factor-A induces plaque expansion in ApoE knock-out mice by promoting de novo leukocyte recruitment.

  2007cited by this paper
• Extracellular RNA mediates endothelial-cell permeability via vascular endothelial growth factor.

  2007cited by this paper
• IL-13受体α2降低血吸虫病肉芽肿的炎症反应并延长宿主存活时间[英]/Mentink-Kane MM,Cheever AW，Thompson RW，et al//Proc Natl Acad Sci U S A

  2005cited by this paper
• Toll-like Receptors 2 and 4 Activate STAT1 Serine Phosphorylation by Distinct Mechanisms in Macrophages*

  2003cited by this paper
• Deposition of Platelet RANTES Triggering Monocyte Recruitment Requires P-Selectin and Is Involved in Neointima Formation After Arterial Injury

  2002cited by this paper
• Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

  2001cited by this paper
• Altered balance between extracellular proteolysis and antiproteolysis is associated with adaptive coronary arteriogenesis.

  2000cited by this paper
• Arterial Injury Increases Expression of Inflammatory Adhesion Molecules in the Carotid Arteries of Apolipoprotein-E-Deficient Mice1

  1999cited by this paper
• Tumor necrosis factor induces enhanced responses to platelet‐activating factor and differentiation in human monocytic Mono Mac 6 cells

  1993cited by this paper
• Blood.

  1989cited by this paper
• Isolation and characterization of an RNA-proteolipid complex associated with the malignant state in humans.

  1985cited by this paper

• Cardiac macrophages and their functions in homeostasis and injury.

  2025cites this paper
• Damage-associated molecular patterns (DAMPs) in vascular diseases

  2025cites this paper
• Bacterial extracellular vesicles in the initiation, progression and treatment of atherosclerosis

  2025cites this paper
• Metabolic Reprogramming Intermediates of Glucose Regulate Macrophage Polarization: An Important Direction for Ameliorating Pulmonary Vascular Remodeling

  2025cites this paper
• Extracellular RNA Drives TNF-α/TNF-Receptor-1 mediated cardiac ischemia/reperfusion injury: Mechanistic insights and therapeutic potential of RNase1.

  2025cites this paper
• Machine learning and SHAP-based identification of RNASE1 linking environmental endocrine-disrupting chemicals exposure to atherosclerosis

  2025cites this paper
• Extracellular RNA in iron-induced hepatic injury: Beyond TLR3 toward an integrated inflammatory axis

  2025cites this paper
• Extracellular RNA as a molecular driver and therapeutic target in abdominal aortic aneurysms

  2025cites this paper
• Targeting Inflammation and Fibrosis in Cardiovascular Disease: Emerging Mechanisms and Therapies

  2025cites this paper
• Damage-associated molecular patterns (DAMPs) in diseases: implications for therapy

  2025cites this paper
• Immune and inflammatory insights in atherosclerosis: development of a risk prediction model through single-cell and bulk transcriptomic analyses

  2024cites this paper
• Extracellular RNA Induces Neutrophil Recruitment Via Toll‐Like Receptor 3 During Venous Thrombosis After Vascular Injury

  2024cites this paper
• naRNA-LL37 composite DAMPs define sterile NETs as self-propagating drivers of inflammation

  2024cites this paper
• Nucleic acid liquid biopsies in cardiovascular disease: Cell-free RNA liquid biopsies in cardiovascular disease.

  2024cites this paper
• Bacterial extracellular vesicles repress the vascular protective factor RNase1 in human lung endothelial cells

  2023cites this paper
• Macrophages in cardiac remodelling after myocardial infarction

  2023cites this paper
• Extracellular Non-Coding RNAs in Cardiovascular Diseases

  2023cites this paper
• Brain alarm by self-extracellular nucleic acids: from neuroinflammation to neurodegeneration

  2023cites this paper
• Ribonuclease 1 Enhances Antitumor Immunity against Breast Cancer by Boosting T cell Activation

  2023cites this paper
• Immune landscape and the key role of APOE+ monocytes of lupus nephritis under the single‐cell and spatial transcriptional vista

  2023cites this paper
• Release of the Pre-Assembled naRNA-LL37 Composite DAMP Re-Defines Neutrophil Extracellular Traps (NETs) as Intentional DAMP Webs

  2022cites this paper
• Functions and cellular signaling by ribosomal extracellular RNA (rexRNA): Facts and hypotheses on a non-typical DAMP.

  2022cites this paper
• Structural insights into EphA4 unconventional activation from prediction of the EphA4 and its complex with ribonuclease 1.

  2022cites this paper
• naRNA is a canonical neutrophil extracellular trap (NET) component and novel inflammation-amplifying composite DAMP

  2022cites this paper
• Emerging biological functions of ribonuclease 1 and angiogenin

  2021influential citation
• Self-extracellular RNA promotes pro-inflammatory response of astrocytes to exogenous and endogenous danger signals

  2021cites this paper
• Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation

  2021cites this paper
• Ribonuclease alleviates hepatic ischemia-reperfusion injury by suppressing excessive cytokine release and TLR3-mediated apoptosis in mice.

  2020cites this paper
• Extracellular RNA as a Versatile DAMP and Alarm Signal That Influences Leukocyte Recruitment in Inflammation and Infection

  2020cites this paper
• p38 and Casein Kinase 2 Mediate Ribonuclease 1 Repression in Inflamed Human Endothelial Cells via Promoter Remodeling Through Nucleosome Remodeling and Deacetylase Complex

  2020cites this paper
• Endothelial Ribonuclease 1 in Cardiovascular and Systemic Inflammation

  2020cites this paper
• Ribonuclease attenuates retinal ischemia reperfusion injury through inhibition of inflammatory response and apoptosis in mice.

  2020cites this paper
• Ribonuclease attenuates acute intestinal injury induced by intestinal ischemia reperfusion in mice.

  2020cites this paper
• The role of nuclear factors as "Find-Me"/alarmin signals and immunostimulation in defective efferocytosis and related disorders.

  2020cites this paper
• Vascular endothelial growth factor‐modified macrophages accelerate reendothelialization and attenuate neointima formation after arterial injury in atherosclerosis‐prone mice

  2019cites this paper
• Molecular mediators of cardioprotective ischemic conditioning : focus on cytokines and chemokines

  2019cites this paper
• Surveillance of Tumour Development: The Relationship Between Tumour-Associated RNAs and Ribonucleases

  2019cites this paper
• coronarios agudos ( IV ) Protección contra el daño miocárdico por isquemia-reperfusión en la práctica clı́nica

  2019cites this paper
• FURIN Inhibition Reduces Vascular Remodeling and Atherosclerotic Lesion Progression in Mice

  2019cites this paper
• Identification of circular RNA Hsa_circ_0001879 and Hsa_circ_0004104 as novel biomarkers for coronary artery disease.

  2019cites this paper
• Phenotype of ribonuclease 1 deficiency in mice

  2019cites this paper
• Inflammation‐mediated deacetylation of the ribonuclease 1 promoter via histone deacetylase 2 in endothelial cells

  2019cites this paper
• Role of Macrophages in Cardioprotection

  2019cites this paper
• Functional roles of the human ribonuclease A superfamily in RNA metabolism and membrane receptor biology.

  2019cites this paper
• The Extraordinary Role of Extracellular RNA in Arteriogenesis, the Growth of Collateral Arteries

  2019cites this paper
• Biological Functions of ribonuclease 1 and angiogenin

  2018influential citation
• Inflammatory Response During Myocardial Infarction.

  2018cites this paper
• Cell-free DNA: the role in pathophysiology and as a biomarker in kidney diseases

  2018cites this paper
• Immune Modulation by Human Secreted RNases at the Extracellular Space

  2018cites this paper
• Einfluss von RNase A auf das Transplantatüberleben im heterotop abdominellen Herztransplantationsmodell an Ratten

  2018cites this paper
• Apolipoprotein E in Cardiovascular Diseases: Novel Aspects of an Old-fashioned Enigma.

  2018cites this paper
• Influence of Medication-Induced Preconditioning or Remote Ischemic Preconditioning on the Intrinsic Vascular Extracellular RNA/Ribonuclease System in Cardioprotection

  2018cites this paper
• The Role of Platelets in Ischemic Conditioning.

  2018cites this paper
• Targeting of Extracellular RNA Reduces Edema Formation and Infarct Size and Improves Survival After Myocardial Infarction in Mice

  2017cites this paper
• Ribonuclease attenuates hepatic ischemia reperfusion induced cognitive impairment through the inhibition of inflammatory cytokines in aged mice.

  2017cites this paper
• Macrophages in vascular inflammation and atherosclerosis

  2017cites this paper
• Double-stranded RNA upregulates the expression of inflammatory mediators in human aortic valve cells through the TLR3-TRIF-noncanonical NF-κB pathway.

  2017cites this paper
• RNase alleviates neurological dysfunction in mice undergoing cardiac arrest and cardiopulmonary resuscitation.

  2017cites this paper
• RNase alleviates neurological dysfunction in mice undergoing cardiac arrest and cardiopulmonary resuscitation

  2017cites this paper
• Extracellular nucleic acids in immunity and cardiovascular responses: between alert and disease

  2017cites this paper
• Antitumor Macrophage Response to Bacillus pumilus Ribonuclease (Binase)

  2017cites this paper
• RNase attenuates acute lung injury induced by ischemia-reperfusion in mice.

  2016cites this paper
• RNA—an initiator of blood coagulation and inflammation

  2016cites this paper
• Serum Surfactant Protein D is Associated with Atherosclerosis of the Carotid Artery in Patients on Maintenance Hemodialysis.

  2016cites this paper
• Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation.

  2016cites this paper
• Influence of Extracellular RNAs, Released by Rheumatoid Arthritis Synovial Fibroblasts, on Their Adhesive and Invasive Properties

  2016cites this paper
• This information is current as on Their Adhesive and Invasive Properties Rheumatoid Arthritis Synovial Fibroblasts , Influence of Extracellular RNAs , Released by Preissner ,

  2016cites this paper
• basic to clinical

  2016cites this paper
• Extracellular RNAs as a chemical initiator for postoperative cognitive dysfunction.

  2016cites this paper
• Ribonuclease (RNase) Prolongs Survival of Grafts in Experimental Heart Transplantation

  2016cites this paper
• From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research”

  2016cites this paper
• Molecular Imaging of Vulnerable Atherosclerotic Plaques in Animal Models

  2016cites this paper
• Coagulation factor XII induces pro-inflammatory cytokine responses in macrophages and promotes atherosclerosis in mice

  2016cites this paper
• Host-derived extracellular RNA promotes adhesion of Streptococcus pneumoniae to endothelial and epithelial cells

  2016cites this paper
• Gene expression profiling reveals potential prognostic biomarkers associated with the progression of heart failure

  2015cites this paper
• Factor XII: a novel target for safe prevention of thrombosis and inflammation

  2015cites this paper
• Progress in interventional cardiology: challenges for the future

  2015cites this paper
• Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside

  2015cites this paper
• Surfing on the Cardiovascular Frontier Wave

  2015cites this paper
• RNase1 as a potential mediator of remote ischaemic preconditioning for cardioprotection†.

  2015cites this paper
• Regulation of monocyte/macrophage polarisation by extracellular RNA

  2015influential citation
• The Damaging Interplay between Extracellular RNA and Tumor-Necrosis-Factor-α in Cardiac Ischemia/Reperfusion Injury: Prevention of Cardiomyocyte Death and Heart Failure by RNase1

  2015cites this paper
• Polysialylation takes place in granulosa cells during apoptotic processes of atretic tertiary follicles

  2015cites this paper
• Noninvasive Molecular Ultrasound Monitoring of Vessel Healing After Intravascular Surgical Procedures in a Preclinical Setup

  2015cites this paper
• Extracellular RNA facilitates hypoxia‐induced leukocyte adhesion and infiltration in the lung through TLR3‐IFN‐γ‐STAT1 signaling pathway

  2015cites this paper
• Protective Effect of RNase on Unilateral Nephrectomy-Induced Postoperative Cognitive Dysfunction in Aged Mice

  2015cites this paper
• Activation of TLR3 Induces Osteogenic Responses in Human Aortic Valve Interstitial Cells through the NF-κB and ERK1/2 Pathways

  2015cites this paper
• Response to letter regarding article "Role of extracellular RNA in atherosclerotic plaque formation in mice".

  2014cites this paper
• RNase1 prevents the damaging interplay between extracellular RNA and tumour necrosis factor-α in cardiac ischaemia/reperfusion injury

  2014influential citation
• Plaque Formation in Mice'' Response to Letter Regarding Article ''Role of Extracellular RNA in Atherosclerotic

  2014cites this paper
• Impact of extracellular RNA on endothelial barrier function

  2014influential citation
• Letter by Chen et al regarding article, "Role of extracellular RNA in atherosclerotic plaque formation in mice".

  2014cites this paper
• Protection against myocardial ischemia-reperfusion injury in clinical practice.

  2014cites this paper
• Bovine Brain Ribonuclease Is the Functional Homolog of Human Ribonuclease 1*

  2014cites this paper
• Protección contra el daño miocárdico por isquemia-reperfusión en la práctica clínica ☆

  2014cites this paper
• The hemostatic system as a regulator of inflammation in atherosclerosis

  2014cites this paper