Review of Preclinical Studies on Treatment of Mucositis and Associated Pain

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Journal of dentistry research

• Publication date

  2014-06-18

• Fields of study

  Medicine

• Identifiers
  DOI 10.1177/0022034514540174PMID 24943201PMCID PMC4213248
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Endothelin Receptor-mediated Responses in Trigeminal Ganglion Neurons

  2013cited by this paper
• UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling

  2013cited by this paper
• Recombinant human epidermal growth factor on oral mucositis induced by intensive chemotherapy with stem cell transplantation

  2013cited by this paper
• Oral mucositis in head and neck cancer: risk, biology, and management.

  2013cited by this paper
• Oral complications of cancer and cancer therapy

  2012cited by this paper
• Pharmacological protection from radiation ± cisplatin-induced oral mucositis.

  2012cited by this paper
• A randomized, double-blind, placebo-controlled trial of misoprostol for oral mucositis secondary to high-dose chemotherapy

  2012cited by this paper
• A novel Peptide to treat oral mucositis blocks endothelial and epithelial cell apoptosis.

  2012cited by this paper
• Effect of vitamin supplementation on cisplatin-induced intestinal epithelial cell apoptosis in Wistar/NIN rats.

  2012cited by this paper
• Oral mucositis in head and neck cancer.

  2011cited by this paper
• Animal models of mucositis: implications for therapy.

  2011cited by this paper
• Nerve Growth Factor Links Oral Cancer Progression, Pain, and Cachexia

  2011cited by this paper
• Personalized medicine for mucositis: Bayesian networks identify unique gene clusters which predict the response to gamma-D-glutamyl-L-tryptophan (SCV-07) for the attenuation of chemoradiation-induced oral mucositis.

  2011cited by this paper
• Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects

  2011cited by this paper
• Endothelin-A receptor antagonism attenuates carcinoma-induced pain through opioids in mice.

  2010cited by this paper
• Polaprezinc prevents oral mucositis associated with radiochemotherapy in patients with head and neck cancer

  2010cited by this paper
• Attenuation of radiation- and chemoradiation-induced mucositis using gamma-D-glutamyl-L-tryptophan (SCV-07).

  2010cited by this paper
• BASIC SCIENCE REVIEW

  2010cited by this paper
• Measuring persistent temporomandibular joint nociception in rats and two mice strains.

  2010cited by this paper
• Peripheral endothelin B receptor agonist‐induced antinociception involves endogenous opioids in mice

  2010cited by this paper
• daptation of a novel operant orofacial testing system to characterize both echanical and thermal pain

  2010cited by this paper
• Endothelins as pronociceptive mediators of the rat trigeminal system: role of ETA and ETB receptors.

  2010cited by this paper
• A novel alternatively spliced isoform of the mu-opioid receptor: functional antagonism

  2010cited by this paper
• The dolognawmeter: a novel instrument and assay to quantify nociception in rodent models of orofacial pain.

  2010cited by this paper
• Pharmacokinetic Analysis and Phase 1 Study of MRX-1024 in Patients Treated with Radiation Therapy with or without Cisplatinum for Head and Neck Cancer

  2010cited by this paper
• Therapeutic effects of recombinant human epidermal growth factor (rhEGF) in a murine model of concurrent chemo- and radiotherapy-induced oral mucositis.

  2010cited by this paper
• Efficacy of palifermin (keratinocyte growth factor-1) in the amelioration of oral mucositis

  2009cited by this paper
• TRPC1 and TRPC6 Channels Cooperate with TRPV4 to Mediate Mechanical Hyperalgesia and Nociceptor Sensitization

  2009influential reference
• A human trial of HSV-mediated gene transfer for the treatment of chronic pain

  2009cited by this paper
• Mechanisms operated by endothelin ETA and ETB receptors in the trigeminal ganglion contribute to orofacial thermal hyperalgesia induced by infraorbital nerve constriction in rats.

  2009cited by this paper
• Cellular and molecular mechanisms of pain.

  2009cited by this paper
• A Common Human μ-Opioid Receptor Genetic Variant Diminishes the Receptor Signaling Efficacy in Brain Regions Processing the Sensory Information of Pain*

  2009cited by this paper
• Animal models of pain: progress and challenges

  2009cited by this paper
• Evaluation of d-Methionine as a Novel Oral Radiation Protector for Prevention of Mucositis

  2008cited by this paper
• Expansion of the human μ-opioid receptor gene architecture: novel functional variants

  2008cited by this paper
• Homogenous amniotic membrane as a biological dressing for oral mucositis in rats: histomorphometric analysis.

  2008cited by this paper
• Effects of Palifermin on Antitumor Activity of Chemotherapeutic and Biological Agents in Human Head and Neck and Colorectal Carcinoma Xenograft Models

  2008cited by this paper
• Effect of epidermal growth factor against radiotherapy-induced oral mucositis in rats.

  2007cited by this paper
• Oral mucositis-related oropharyngeal pain and correlative tumor necrosis factor-alpha expression in adult oncology patients undergoing hematopoietic stem cell transplantation.

  2007cited by this paper
• Attenuated cold sensitivity in TRPM8 null mice.

  2007cited by this paper
• Elevated salivary endothelin levels in oral cancer patients--a pilot study.

  2007cited by this paper
• Transient receptor potential cation channels in disease.

  2007cited by this paper
• Management of pain in cancer patients with oral mucositis: follow-up of multiple doses of doxepin oral rinse.

  2007cited by this paper
• A protective role for keratinocyte growth factor in a murine model of chemotherapy and radiotherapy-induced mucositis.

  2006cited by this paper
• Endothelin ETA and ETB receptor expression in the human trigeminal ganglion.

  2006cited by this paper
• Effects of ceramide inhibition on experimental radiation-induced oral mucositis.

  2005cited by this paper
• Reduction of radiochemotherapy-induced early oral mucositis by recombinant human keratinocyte growth factor (palifermin): experimental studies in mice.

  2005influential reference
• Bite force measurement in awake rats: a behavioral model for persistent orofacial muscle pain and hyperalgesia.

  2005cited by this paper
• Keratinocyte growth factor/fibroblast growth factor 7, a homeostatic factor with therapeutic potential for epithelial protection and repair.

  2004cited by this paper
• Oral mucositis in cancer therapy.

  2004influential reference
• Basic fibroblast growth factor and epidermal growth factor reverse impaired ulcer healing of the rabbit oral mucosa.

  2003influential reference
• Oral mucositis: A challenging complication of radiotherapy, chemotherapy, and radiochemotherapy: Part 1, pathogenesis and prophylaxis of mucositis

  2003cited by this paper
• Preclinical characterization of CG53135 (FGF-20) in radiation and concomitant chemotherapy/radiation-induced oral mucositis.

  2003cited by this paper
• Preclinical Characterization of CG 53135 ( FGF-20 ) in Radiation and Concomitant Chemotherapy / Radiation-induced Oral Mucositis

  2003cited by this paper
• BMC Developmental Biology BioMed Central

  2003influential reference
• Topical Transforming Growth Factor-&bgr;3 in the Prevention or Alleviation of Chemotherapy-Induced Oral Mucositis in Patients with Lymphomas or Solid Tumors

  2001cited by this paper
• Transforming growth factor‐β3 protects murine small intestinal crypt stem cells and animal survival after irradiation, possibly by reducing stem‐cell cycling

  2000cited by this paper
• Phase I study of transforming growth factor-beta3 mouthwashes for prevention of chemotherapy-induced mucositis.

  1999cited by this paper
• Keratinocyte growth factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortality.

  1998cited by this paper
• Advanced Glycation End Product-Induced Activation of NF-κB is Suppressed by α-Lipoic Acid in Cultured Endothelial Cells

  1997cited by this paper
• Advanced glycation end product-induced activation of NF-kappaB is suppressed by alpha-lipoic acid in cultured endothelial cells.

  1997cited by this paper
• A double-blind, placebo-controlled, randomized trial to evaluate the role of tetrachlorodecaoxide in the management of chemotherapy-induced oral mucositis.

  1997cited by this paper
• An animal model for mucositis induced by cancer chemotherapy.

  1990cited by this paper
• Accelerated repopulation of mouse tongue epithelium during fractionated irradiations or following single doses.

  1990cited by this paper

• Addressing Pain in Oral Mucositis: Narrative Review of Current Practices and Emerging Treatments

  2025cites this paper
• Bacterial Decolonization With Mupirocin Ointment for Acute Radiation Oral Mucositis Prevention: A Phase 3 Randomized Clinical Trial.

  2025cites this paper
• Exploring the Influence of Sex on the Development of Radiation-Induced Oral Mucositis

  2025cites this paper
• Recent advances in the treatment of oral ulcerative mucositis from clinical and basic perspectives.

  2024cites this paper
• Efficacy and safety of NAHAO® hydrogel in amelioration of chemoradiotherapy-induced oral mucositis: an preliminary clinical study(ChiCTR2200064766).

  2023cites this paper
• Sprayable NAHAO® hydrogel alleviates pain and accelerates rat oral mucositis wound healing.

  2022cites this paper
• Pharmacological Management of Neuropathic Pain after Radiotherapy in Head and Neck Cancer Patients: A Systematic Review

  2022cites this paper
• Neurotrophin Pathway Receptors NGFR and TrkA Control Perineural Invasion, Metastasis, and Pain in Oral Cancer

  2022cites this paper
• Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: children and adolescents

  2021influential citation
• Comparison of topical agents that are effective against oral mucositis associated with chemotherapy using a rat anticancer agent-induced oral mucositis model

  2021cites this paper
• Rehabilitation strategies and results in patients treated with chemoradiotherapy/radiotherapy for head and neck cancer: Institutional  experience

  2021cites this paper
• Nattokinase crude extract enhances oral mucositis healing

  2021cites this paper
• Oral Complications of Head and Neck Cancer Therapy

  2021cites this paper
• A Phase II Randomized Clinical Trial and Mechanistic Studies Using Improved Probiotics to Prevent Oral Mucositis Induced by Concurrent Radiotherapy and Chemotherapy in Nasopharyngeal Carcinoma

  2021cites this paper
• Low-frequency electromagnetic field influences human oral mucosa keratinocyte viability in response to lipopolysaccharide or minocycline treatment in cell culture conditions.

  2021cites this paper
• The usefulness of the Electronic Patient Visit Assessment (ePVA)© as a clinical support tool for real-time interventions in head and neck cancer.

  2020cites this paper
• Effects of Topical Hangeshashinto (TJ-14) on Chemotherapy-Induced Oral Mucositis

  2020influential citation
• Prefácio

  2020cites this paper
• The positive impact of dental care on the patient's quality of life after cancer treatment: a case report

  2020cites this paper
• Histological and Immunohistochemical Evaluation of the Ameliorating Role of Propolis and/or Intermittent Fasting on Induced Oral Mucositis in Albino Rats.

  2020cites this paper
• CMAR_A_238306 1069..1078

  2020cites this paper
• Assessment of oral mucositis degree due to cytostatic treatment in patients with malignant lymphomas

  2019cites this paper
• Heparin treatment mitigates radiation-induced oral mucositis in mice by interplaying with repopulation processes

  2019cites this paper
• EGFR-TKI不良反应管理专家共识

  2019cites this paper
• Orofacial Pain in Patients with Cancer and Mucosal Diseases

  2019cites this paper
• Morphine consumption is associated with systemic inflammation in children undergoing allogeneic hematopoietic stem cell transplantation

  2019cites this paper
• Gliclazide Prevents 5-FU-Induced Oral Mucositis by Reducing Oxidative Stress, Inflammation, and P-Selectin Adhesion Molecules

  2019cites this paper
• Radiation-Related Dysphagia: From Pathophysiology to Clinical Aspects

  2019cites this paper
• Effects of ozone nano-bubble water on mucositis induced by cancer chemotherapy

  2019cites this paper
• Oral Pain in the Cancer Patient

  2019cites this paper
• Oral Pain in the Cancer Patient.

  2019cites this paper
• Honoring a champion of Oral Medicine: Professor Crispian Scully.

  2018cites this paper
• Swallowing Dysfunction After Radiotherapy and Chemotherapy

  2018cites this paper
• Prevention and treatment of oral mucositis pain following cancer therapy

  2018influential citation
• A pilot study of the clinical evidence for the methodology for prevention of oral mucositis during cancer chemotherapy by measuring salivary excretion of 5-fluorouracil

  2018cites this paper
• Systemic administration of heparin ameliorates radiation-induced oral mucositis—preclinical studies in mice

  2018cites this paper
• The Effect of Mucoadhesive Gel Containing Satureja Hortensis Extract 1% on Severity of Chemotherapy-induced Mucositis Pain in Children: A Randomized Clinical Trial

  2018influential citation
• New Frontiers in the Pathobiology and Treatment of Cancer Regimen-Related Mucosal Injury

  2017cites this paper
• Oral mucositis and saliva IgA, IgG and IgM concentration during anti-tumor treatment in children suffering from acute lymphoblastic leukemia.

  2017cites this paper
• The Effect of Grape Seed Extract and Cetuximab Drug on Mucositis of Experimental Rats

  2017cites this paper
• Absorption of Bupivacaine after Administration of a Lozenge as Topical Treatment for Pain from Oral Mucositis

  2017cites this paper
• Cancer and orofacial pain

  2016cites this paper
• A novel lozenge containing bupivacaine as topical alleviation of oral mucositis pain in patients with head and neck cancer: a pilot study

  2016cites this paper
• Distinct TRPV1- and TRPA1-based mechanisms underlying enhancement of oral ulcerative mucositis-induced pain by 5-fluorouracil

  2016cites this paper
• Evaluación de terapias alternativas en mucositis oral experimental

  2016cites this paper
• Oral mucosal injury caused by mammalian target of rapamycin inhibitors: emerging perspectives on pathobiology and impact on clinical practice

  2016influential citation
• Pathophysiology of Radiation-Induced Dysphagia in Head and Neck Cancer

  2016cites this paper
• Differential Superiority of Heavy Charged-Particle Irradiation to X-Rays: Studies on Biological Effectiveness and Side Effect Mechanisms in Multicellular Tumor and Normal Tissue Models

  2016cites this paper
• Modulation of radiation-induced oral mucositis by thalidomide

  2016cites this paper
• SECONDARY HEADACHE ( M ROBBINS , SECTION EDITOR ) Cancer and Referred Facial Pain

  2015cites this paper
• Modulation of radiation-induced oral mucositis by pentoxifylline: Preclinical studies

  2015cites this paper
• The Effects of Ionizing Radiation on the Oral Cavity.

  2015cites this paper
• Local hypoxia in oral mucosa (mouse) during daily fractionated irradiation - Effect of pentoxifylline.

  2015cites this paper
• The Challenges of Cancer Pain Assessment

  2015cites this paper
• Cancer and Referred Facial Pain

  2015cites this paper