Olivocochlear Efferents: Anatomy, Physiology, Function, and the Measurement of Efferent Effects in Humans

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Ear and Hearing

• Publication date

  2006-12-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1097/01.aud.0000240507.83072.e7PMID 17086072
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Time-course of the human medial olivocochlear reflex.

  2006influential reference
• MEDIAL OLIVOCOCHLEAR EFFERENT EFFECTS ON BASILAR MEMBRANE RESPONSES TO SOUND

  2006cited by this paper
• MEDIAL-OLIVOCOCHLEAR-EFFERENT EFFECTS ON BASILAR-MEMBRANE AND AUDITORY-NERVE RESPONSES TO CLICKS: EVIDENCE FOR A NEW MOTION WITHIN THE COCHLEA

  2006cited by this paper
• Lateralization of the effects of the benzodiazepine drug oxazepam on medial olivocochlear system activity in humans.

  2005cited by this paper
• Physiological Mechanisms of Onset Adaptation and Contralateral Suppression of DPOAEs in the Rat

  2005cited by this paper
• Human efferent adaptation of DPOAEs in the L1,L2 space.

  2005cited by this paper
• Where Is the Spike Generator of the Cochlear Nerve? Voltage-Gated Sodium Channels in the Mouse Cochlea

  2005cited by this paper
• Medial-olivocochlear-efferent inhibition of the first peak of auditory-nerve responses: evidence for a new motion within the cochlea.

  2005cited by this paper
• Medial olivocochlear reflex interneurons are located in the posteroventral cochlear nucleus: A kainic acid lesion study in guinea pigs

  2005cited by this paper
• Evidence for a bipolar change in distortion product otoacoustic emissions during contralateral acoustic stimulation in humans.

  2005influential reference
• Asymmetric Cochlear Processing Mimics Hemispheric Specialization

  2004cited by this paper
• Mechanisms of Mammalian Otoacoustic Emission and their Implications for the Clinical Utility of Otoacoustic Emissions

  2004cited by this paper
• The Efficacy of AM Noise for Activating the Human MOC Reflex Measured Using SFOAEs.

  2004cited by this paper
• Medial Olivocochlear Efferent Reflex in Humans: Otoacoustic Emission (OAE) Measurement Issues and the Advantages of Stimulus Frequency OAEs

  2003cited by this paper
• Prestin and the Dynamic Stiffness of Cochlear Outer Hair Cells

  2003cited by this paper
• Modulation of cochlear afferent response by the lateral olivocochlear system: activation via electrical stimulation of the inferior colliculus.

  2003cited by this paper
• Contralateral acoustic reflex thresholds for tonal activators using wideband energy reflectance and admittance.

  2003cited by this paper
• Fast Effects of Efferent Stimulation on Basilar Membrane Motion

  2003cited by this paper
• [Are we sectioning the cochlear efferent system during vestibular neurotomy?].

  2003cited by this paper
• Rapid adaptation of the 2 f 1 ^ f 2 DPOAE in humans : Binaural and contralateral stimulation e ¡ ects 1

  2003cited by this paper
• Separate mechanical processes underlie fast and slow effects of medial olivocochlear efferent activity

  2003cited by this paper
• Olivocochlear innervation in the mouse: Immunocytochemical maps, crossed versus uncrossed contributions, and transmitter colocalization

  2003cited by this paper
• Contralateral Sound Stimulation Suppresses the Compound Action Potential from the Auditory Nerve in Humans

  2002influential reference
• Inputs from the cochlea and the inferior colliculus converge on olivocochlear neurones.

  2002cited by this paper
• Tuning of Ipsilateral, Contralateral and Binaural Medial Efferent Reflexes in Humans.

  2002cited by this paper
• Reciprocal Innervation of Outer Hair Cells in a Human Infant

  2002cited by this paper
• Modulation of cochlear hair cells by the auditory cortex in the mustached bat

  2002cited by this paper
• Influence of Contralateral Stimulation by Two-tone Complexes, Narrow-band and Broad-band Noise Signals on the 2f 1 -f 2 Distortion Product Otoacoustic Emission Levels in Humans

  2002cited by this paper
• Influence of focused auditory attention on cochlear activity in humans.

  2001cited by this paper
• Asymmetrical localization of benzodiazepine receptors in the human auditory cortex.

  2001cited by this paper
• α10: A determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells

  2001cited by this paper
• Adaptation of Distortion Product Otoacoustic Emission in Humans

  2001cited by this paper
• Mechanics of the mammalian cochlea.

  2001cited by this paper
• Dopamine inhibition of auditory nerve activity in the adult mammalian cochlea

  2001cited by this paper
• Effects of Olivocochlear Feedback on Distortion Product Otoacoustic Emissions in Guinea Pig

  2001influential reference
• Estimating the Acoustic Reflex Threshold from Wideband Measures of Reflectance, Admittance, and Power

  2001cited by this paper
• Auditory-nerve-fiber responses to high-level clicks: interference patterns indicate that excitation is due to the combination of multiple drives.

  2000cited by this paper
• Centrifugal Pathways Protect Hearing Sensitivity at the Cochlea in Noisy Environments That Exacerbate the Damage Induced by Loud Sound

  2000cited by this paper
• Prevalence and ultrastructural morphology of axosomatic synapses on spiral ganglion cells in humans of different ages.

  2000cited by this paper
• Auditory perception in vestibular neurectomy subjects.

  2000cited by this paper
• Tones disappear faster in the right ear than in the left

  2000cited by this paper
• Medial efferent effects on auditory-nerve responses to tail-frequency tones II: alteration of phase.

  2000cited by this paper
• Activation of medial olivocochlear e¡erent system in humans: in£uence of stimulus bandwidth

  2000influential reference
• Predicting Vulnerability to Acoustic Injury with a Noninvasive Assay of Olivocochlear Reflex Strength

  2000cited by this paper
• Development of human cochlear active mechanism asymmetry: involvement of the medial olivocochlear system?

  1999cited by this paper
• Sinusoidal amplitude modulation alters contralateral noise suppression of evoked otoacoustic emissions in humans.

  1999cited by this paper
• The Human Olivocochlear System: Organization and Development

  1999cited by this paper
• Medial efferent effects on auditory-nerve responses to tail-frequency tones. I. Rate reduction.

  1999cited by this paper
• Evoked otoacoustic emissions arise by two fundamentally different mechanisms: a taxonomy for mammalian OAEs.

  1999cited by this paper
• Maturation of medial efferent system function in humans.

  1999cited by this paper
• Influence of handedness on peripheral auditory asymmetry

  1998cited by this paper
• Effects of bilateral olivocochlear lesions on vowel formant discrimination in cats.

  1998cited by this paper
• Functional asymmetries of crossed and uncrossed medial olivocochlear efferent pathways in humans.

  1998cited by this paper
• Synaptic specializations associated with the outer hair cells of the Japanese macaque.

  1997cited by this paper
• Apoptosis in epithelial hyperplastic laryngeal lesions.

  1997cited by this paper
• Medial olivocochlear efferent system in humans studied with amplitude-modulated tones.

  1997cited by this paper
• Auditory efferents involved in speech‐in‐noise intelligibility

  1997cited by this paper
• The effect of contralateral broad-band noise on acoustic distortion products from the human ear.

  1997influential reference
• Frequency-dependent enhancement of basilar membrane velocity during olivocochlear bundle stimulation.

  1997cited by this paper
• Characteristics of transient-evoked otoacoustic emissions (TEOES) in neonates.

  1997cited by this paper
• Medial efferent inhibition suppresses basilar membrane responses to near characteristic frequency tones of moderate to high intensities.

  1997cited by this paper
• Acetylcholine, Outer Hair Cell Electromotility, and the Cochlear Amplifier

  1997cited by this paper
• Relationship between auditory intensity discrimination in noise and olivocochlear efferent system activity in humans.

  1997cited by this paper
• Olivocochlear reflex assays: effects of contralateral sound on compound action potentials versus ear-canal distortion products.

  1996cited by this paper
• Effect of contralateral acoustic stimulation on the growth of click-evoked otoacoustic emissions in humans.

  1996cited by this paper
• The influence of evoking stimulus level on the neural suppression of transient evoked otoacoustic emissions.

  1996cited by this paper
• Acetylcholine-induced potassium current of guinea pig outer hair cells: its dependence on a calcium influx through nicotinic-like receptors

  1996cited by this paper
• The effect of efferent stimulation on basilar membrane displacement in the basal turn of the guinea pig cochlea

  1996cited by this paper
• Involvement of the olivocochlear bundle in the detection of tones in noise.

  1996cited by this paper
• Medial efferent inhibition produces the largest equivalent attenuations at moderate to high sound levels in cat auditory-nerve fibers.

  1996cited by this paper
• Ipsilateral suppression of transient evoked otoacoustic emission: role of the medial olivocochlear system.

  1996cited by this paper
• Synaptic transmission at vertebrate hair cells.

  1996cited by this paper
• The ipsilaterally evoked olivocochlear reflex causes rapid adaptation of the 2f1-f2 distortion product otoacoustic emission.

  1996cited by this paper
• Physiology of Olivocochlear Efferents

  1996cited by this paper
• Contralateral suppression of evoked otoacoustic emissions and detection of a multi-tone complex in noise.

  1995cited by this paper
• Auditory phenotyping of heterozygous sound-responsive (+/dn) and deafness (dn/dn) mice.

  1995cited by this paper
• Sound stimulation induces Fos‐related antigens in cells with common morphological properties throughout the auditory brainstem

  1995cited by this paper
• Evidence of a medial olivocochlear involvement in contralateral suppression of otoacoustic emissions in humans.

  1995cited by this paper
• Clinical application of ultrasonic blood rheography in vertebral artery for vertigo.

  1995cited by this paper
• Binaural noise suppresses linear click-evoked otoacoustic emissions more than ipsilateral or contralateral noise.

  1995cited by this paper
• Efferent-mediated protection from acoustic overexposure: relation to slow effects of olivocochlear stimulation.

  1995cited by this paper
• A novel cholinergic "slow effect" of efferent stimulation on cochlear potentials in the guinea pig

  1995cited by this paper
• Effects of vestibular neurectomy on intensity discrimination and speech perception in noise

  1994cited by this paper
• Effects of Bilateral Olivocochlear Lesions on Pure-Tone Intensity Discrimination in Cats.

  1994cited by this paper
• Immunocytochemical detection of choline acetyltransferase in the human organ of Corti.

  1994cited by this paper
• Alpha 9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells.

  1994cited by this paper
• Auditory selective attention in the human cochlea.

  1994cited by this paper
• On the role of the olivocochlear bundle in hearing: a case study.

  1994cited by this paper
• α9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells

  1994cited by this paper
• Contralateral auditory stimulation alters acoustic distortion products in humans.

  1993cited by this paper
• Frequency analysis of the contralateral suppression of evoked otoacoustic emissions by narrow-band noise.

  1993cited by this paper
• Patterns of innervation of outer hair cells in a chimpanzee: I. Afferent and reciprocal synapses.

  1993cited by this paper
• Neurotransmitters and neuromodulators of the mammalian cochlea.

  1993influential reference
• Relationship of descending inferior colliculus projections to olivocochlear neurons

  1993cited by this paper
• Transiently evoked otoacoustic emission amplitudes change with changes of directed attention.

  1993cited by this paper
• Contralateral suppression of non-linear click-evoked otoacoustic emissions.

  1993cited by this paper
• Effect of contralateral sound stimulation on the distortion product 2f1-f2 in humans: evidence of a frequency specificity.

  1993cited by this paper
• Antimasking effects of the olivocochlear reflex. II. Enhancement of auditory-nerve response to masked tones.

  1993cited by this paper
• Input from the inferior colliculus to medial olivocochlear neurons in the rat: a double label study with PHA-L and cholera toxin.

  1993cited by this paper
• Ionic currents in cochlear hair cells.

  1992cited by this paper

• Dynamic sensor adaptation based on efferent feedback for adaptive bio-inspired sound source localization

  2026cites this paper
• Impaired development of the medial olivocochlear system in a KCNQ4-deficient mouse model

  2026cites this paper
• Mechanisms of auditory enhancement in younger and older adults.

  2025cites this paper
• Effects of stimuli and contralateral noise levels on auditory cortical potentials recorded in school-age children

  2025cites this paper
• Deciphering Auditory Hyperexcitability in Otogl Mutant Mice Unravels an Auditory Neuropathy Mechanism

  2025cites this paper
• Auditory efferents facilitate intensity change detection in humans: evidence from concurrent ear, brain, and behavior measures

  2025influential citation
• Effects of Contralateral Noise on Cortical Auditory Evoked Potential Latencies and Amplitudes.

  2025cites this paper
• ATP-gated P2x7 receptors express at type II auditory nerves and required for efferent hearing control and noise protection

  2025cites this paper
• Modeling the impact of cochlear nerve degeneration on speech recognition performance

  2025cites this paper
• DPOAE growth function in schoolchildren with impaired temporal ordering skills

  2025cites this paper
• Medial olivocochlear system and tinnitus: A systematic review

  2025cites this paper
• Cochlear neural contributions to triple network changes in tinnitus, hyperacusis & misophonia? A perspective review.

  2025cites this paper
• The effects of broadband elicitor duration on transient-evoked otoacoustic emissions and a psychoacoustic measure of gain reduction

  2025cites this paper
• Cochlear histopathology in macaques after noise-induced temporary threshold shifts

  2025influential citation
• The Medial Olivocochlear Efferent Pathway Potentiates Cochlear Amplification in Response to Hearing Loss

  2025cites this paper
• Impact of Pesticide Exposure on Auditory Health: Mechanisms, Efferent System Disruption, and Public Health Implications.

  2025cites this paper
• Sources of Microstructure in Mammalian Cochlear Responses

  2025cites this paper
• Attention to Speech Modulates Distortion Product Otoacoustic Emissions Evoked by Speech-derived Stimuli in Humans

  2025cites this paper
• Relationship among speech perception in noise, auditory inhibitory measures and working memory in neurotypical adults.

  2025cites this paper
• Short-term buildup of contralateral olivocochlear emission suppression and its effect on the words-in-noise test.

  2025cites this paper
• Medial olivocochlear efferent modulation of cochlear micromechanics requires P2X4 expression in outer hair cells

  2025cites this paper
• Assessment of the medial olivocochlear reflex in normal-hearing right-handed subjects using auditory brainstem response: a pilot study

  2025cites this paper
• The auditory brainstem response to natural speech is not affected by selective attention

  2025cites this paper
• Listening to the Mind: Earable Acoustic Sensing of Cognitive Load

  2025cites this paper
• Cognitive Load Monitoring via Earable Acoustic Sensing

  2025cites this paper
• How Exceptional Is the Ear?

  2025cites this paper
• Medial Olivocochlear Efferent Modulation of Cochlear Micromechanics Requires P2X4 Receptor in Outer Hair Cells

  2025cites this paper
• Effects of ipsilateral, contralateral, and bilateral noise precursors on psychoacoustical tuning curves in humans.

  2024influential citation
• Auditory changes in awake guinea pigs exposed to overcompressed music.

  2024cites this paper
• Associations between the medial olivocochlear reflex, middle-ear muscle reflex, and sentence-in-noise recognition using steady and pulsed noise elicitors.

  2024cites this paper
• Evidence for proactive and retroactive temporal pattern analysis in simultaneous maskinga).

  2024cites this paper
• Mapping the Mind-Brain Duality to a Digital-Analog Perceptual Duality

  2024cites this paper
• Speech-DPOAEs for probing speech processing in the inner ear

  2024cites this paper
• Evaluation of the Effect of Age on the Contralateral Acoustic Reflex Suppression Test in Individuals With Normal Hearing.

  2024cites this paper
• Alpha9alpha10 knockout mice show altered physiological and behavioral responses to signals in masking noise

  2024cites this paper
• Relationships between the expectations based on the regularity of preceding sound sequences and the medial olivocochlear reflex

  2024cites this paper
• Neural control and innate self-tuning of the hair cell’s active process

  2024cites this paper
• Speech Separation With Pretrained Frontend to Minimize Domain Mismatch

  2024cites this paper
• Beyond the Sound Waves: A Comprehensive Exploration of the Burn-In Phenomenon in Audio Equipment Across Physiological, Psychological, and Societal Domains

  2024cites this paper
• Medial Olivocochlear Reflex Strength in Ears With Low-to-Moderate Annual Noise Exposure.

  2023cites this paper
• Kadınlarda Kontralateral TEOAE Supresyon: Kısa Süreli Test-Tekrar Test Güvenilirlik Çalışması

  2023cites this paper
• Evidence of cochlear neural degeneration in normal-hearing subjects with tinnitus

  2023cites this paper
• Conserved features of eye movement related eardrum oscillations (EMREOs) across humans and monkeys

  2023cites this paper
• The right ear advantage – a perspective from speech perception in noise test

  2023cites this paper
• Peripheral Auditory Function in Tanzanian Children Living With HIV With Clinically Normal Hearing

  2023cites this paper
• Estimation of efferent inhibition and speech in noise perception on vocal musicians and music sleepers: A comparative study

  2023cites this paper
• Parametric information about eye movements is sent to the ears

  2023cites this paper
• Role of the medial olivocochlear efferent auditory system in speech perception in noise: a systematic review and meta-analyses

  2023influential citation
• Alpha9alpha10 knockout mice show altered physiological and behavioral responses to signals in masking noise

  2023cites this paper
• The effects of broadband elicitor duration on a psychoacoustic measure of cochlear gain reduction.

  2023cites this paper
• Contextual Lateralization Based on Interaural Level Differences Is Preshaped by the Auditory Periphery and Predominantly Immune Against Sequential Segregation

  2023influential citation
• Subcortical Auditory Model including Efferent Dynamic Gain Control with Inputs from Cochlear Nucleus and Inferior Colliculus

  2023cites this paper
• Auditory brainstem mechanisms likely compensate for self-imposed peripheral inhibition

  2023cites this paper
• A Clinically Viable Medial Olivocochlear Reflex Assay Using Transient-Evoked Otoacoustic Emissions

  2023influential citation
• Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Students Aged Between 8 and 12 years

  2023cites this paper
• Speech Perception in Noise and Medial Olivocochlear Reflex: Effects of Age, Speech Stimulus, and Response-Related Variables

  2023cites this paper
• IIANet: An Intra- and Inter-Modality Attention Network for Audio-Visual Speech Separation

  2023cites this paper
• Multisensory decisions from self to world

  2023cites this paper
• Magnitude of medial olivocochlear reflex assayed by tone-burst-evoked otoacoustic emissions: reliability and comparison with click-evoked emissions

  2023cites this paper
• Abnormal outer hair cell efferent innervation in Hoxb1-dependent sensorineural hearing loss

  2023cites this paper
• Assessing Medial Olivocochlear Reflex Strengths via Auditory Brainstem Response: Measurement and Variability in Normal-Hearing Individuals.

  2023cites this paper
• Middle ear muscle and medial olivocochlear activity inferred from individual human ears via cochlear potentials.

  2023cites this paper
• Inhibitory effect of contralateral noise on transient otoacoustic emissions in infants with congenital syphilis.

  2023cites this paper
• Conserved features of eye movement related eardrum oscillations (EMREOs) across humans and monkeys

  2023cites this paper
• Intensity discrimination and neural representation of a masked tone in the presence of three types of masking release

  2023cites this paper
• Auditory Deprivation during Development Alters Efferent Neural Feedback and Perception

  2022cites this paper
• Visualizing Contralateral Suppression of Hearing Sensitivity via Acoustic and Electric Brainstem Audiometry in Bimodal Cochlear Implant Patients: A Feasibility Study

  2022influential citation
• The purinergic receptors 2X3 on spiral ganglion neurons enhance the medial olivocochlear reflex in mice after long-term moderate noise exposure

  2022cites this paper
• Contralateral inhibition of distortion product otoacoustic emissions in young noise-exposed Veterans.

  2022cites this paper
• Clinical and investigational tools for monitoring noise-induced hyperacusis.

  2022cites this paper
• Evaluation of Medial Olivocochlear Neural Efferent Pathway in Tinnitus Perception in Normal-hearing Individuals.

  2022cites this paper
• Adaptation in auditory processing

  2022cites this paper
• Signatures of cochlear processing in neuronal coding of auditory information.

  2022cites this paper
• Transient decrease in sound tolerance levels following hearing deprivation in normal-hearing subjects

  2022cites this paper
• Contralateral suppression of transient evoked otoacoustic emissions in adults: A normative study

  2022cites this paper
• Animal-to-Human Translation Difficulties and Problems With Proposed Coding-in-Noise Deficits in Noise-Induced Synaptopathy and Hidden Hearing Loss

  2022cites this paper
• Loss of central mineralocorticoid or glucocorticoid receptors impacts auditory nerve processing in the cochlea

  2022cites this paper
• Lack of correlation between medial olivocochlear reflex strength and sentence recognition in noise

  2022influential citation
• The Long and Winding Road—Vestibular Efferent Anatomy in Mice

  2022cites this paper
• Expectations of the timing and intensity of a stimulus propagate to the auditory periphery through the medial olivocochlear reflex

  2022cites this paper
• Evaluation of the Auditory System in Autistic Children Using Evoked Otoacoustic Emissions and a Contralateral Suppression Test

  2022cites this paper
• Abnormal neural adaptation consequent to combined exposure to jet fuel and noise

  2022cites this paper
• The Analysis of Mammalian Hearing Systems Supports the Hypothesis That Criticality Favors Neuronal Information Representation but Not Computation

  2022influential citation
• Electrical signaling in cochlear efferents is driven by an intrinsic neuronal oscillator

  2022cites this paper
• Efeito inibitório da via auditiva eferente na síndrome de Turner

  2022cites this paper
• Effect of menstrual cycle on outer hair cells (OHC’s) and efferent auditory pathway in females – An Indian study

  2022cites this paper
• Comparison of otoacoustic emissions in tinnitus and hyperacusis in adults with normal hearing sensitivity

  2022cites this paper
• Efeito inibitório da via eferente auditiva no transtorno de processamento auditivo central

  2021cites this paper
• Controlled (re)evaluation of the relationship between speech perception in noise and contralateral suppression of otoacoustic emissions.

  2021cites this paper
• The comprehensive audiological evaluation in young violinists: the medial olivocochlear system, high frequency thresholds, and the auditory figure ground test

  2021cites this paper
• Effects of Multisession Anodal Electrical Stimulation of the Auditory Cortex on Temporary Noise-Induced Hearing Loss in the Rat

  2021cites this paper
• Effect of Musical Experience on Cochlear Frequency Resolution: An Estimation of PTCs, DLF and SOAEs

  2021cites this paper
• Toward an Individual Binaural Loudness Model for Hearing Aid Fitting and Development

  2021cites this paper
• Reducing Auditory Nerve Excitability by Acute Antagonism of Ca2+-Permeable AMPA Receptors

  2021cites this paper
• Oncomodulin Delays Age-Related Hearing Loss in C57 and CBA Mice

  2021cites this paper
• Synaptic Contributions to Cochlear Outer Hair Cell Ca2+ Dynamics

  2021cites this paper
• Reflejo olivococlear contralateral y su relación con ansiedad y calidad de vida en pacientes con tinnitus

  2021cites this paper
• The Role of the Medial Olivocochlear Reflex in Acceptable Noise Level in Adults

  2021cites this paper
• Reliability of Contralateral Suppression in Evoked Distortion Product Otoacoustic Emissions

  2021cites this paper
• ORKESTRA SANATÇILARINDA AFFERENT ve EFFERENT İŞİTME SİSTEMİNİN DEĞERLENDİRİLMESİ

  2021cites this paper