Basic fibroblast growth factor in patients with intermittent claudication: results of a phase I trial.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Journal of the American College of Cardiology

• Publication date

  2000-10-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/S0735-1097(00)00882-2PMID 11028477
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: results of a phase I randomized, double-blind, placebo-controlled trial.

  1999cited by this paper
• Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia.

  1998cited by this paper
• Induction of neoangiogenesis in ischemic myocardium by human growth factors: first clinical results of a new treatment of coronary heart disease.

  1998cited by this paper
• Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia.

  1998cited by this paper
• Factors controlling ocular angiogenesis.

  1997cited by this paper
• Intermittent claudication. A risk profile from The Framingham Heart Study.

  1997cited by this paper
• Basic fibroblast growth factor increases collateral blood flow in rats with femoral arterial ligation.

  1996cited by this paper
• Comparative effects of basic fibroblast growth factor and vascular endothelial growth factor on coronary collateral development and the arterial response to injury.

  1996cited by this paper
• Effects of chronic systemic administration of basic fibroblast growth factor on collateral development in the canine heart.

  1995cited by this paper
• The role of growth factors in the development of diabetic retinopathy.

  1995cited by this paper
• Basic fibroblast growth factor enhances myocardial collateral flow in a canine model.

  1994cited by this paper
• Epidemiology of peripheral arterial disease.

  1994cited by this paper
• Salvage of infarcted myocardium by angiogenic action of basic fibroblast growth factor.

  1992cited by this paper
• Collateral Perfusion: The Role of Endothelium‐Derived Relaxing Factor and Effects of Vasodilators

  1992cited by this paper
• Enhanced angiogenesis and growth of collaterals by in vivo administration of recombinant basic fibroblast growth factor in a rabbit model of acute lower limb ischemia: dose-response effect of basic fibroblast growth factor.

  1992cited by this paper
• bFGF enhances the development of the collateral circulation after acute arterial occlusion.

  1992cited by this paper
• Hypotensive activity of fibroblast growth factor.

  1991cited by this paper
• Progressive vs single-stage treadmill tests for evaluation of claudication.

  1991cited by this paper
• Preclinical and Clinical Studies with Recombinant Human Basic Fibroblast Growth Factor

  1991cited by this paper
• Peripheral vascular disease: a public health perspective.

  1990cited by this paper
• Role of extracellular matrix in the action of basic fibroblast growth factor: Matrix as a source of growth factor for long‐term stimulation of plasminogen activator production and DNA synthesis

  1989cited by this paper
• Drug treatment of intermittent claudication

  1989cited by this paper
• Drug treatment of intermittent claudication: a critical analysis of the methods and findings of published clinical trials, 1965-1985.

  1988cited by this paper
• Pharmacologic vasodilators in the coronary circulation.

  1987cited by this paper
• The sensitivity, specificity, and predictive value of traditional clinical evaluation of peripheral arterial disease: results from noninvasive testing in a defined population.

  1985cited by this paper
• The measurement of volume changes in human limbs

  1953cited by this paper
• PERIPHERAL VASCULAR DISEASE

  1940cited by this paper

• bFGF-Loaded PDA Microparticles Enhance Vascularization of Engineered Skin with a Concomitant Increase in Leukocyte Recruitment

  2026cites this paper
• A novel subcutaneous islet transplantation method using a bioabsorbable medical device to facilitate the creation of a highly vascularized transplantation site

  2025cites this paper
• Optimal injection sites for therapeutic angiogenesis: HGF-mediated regulation of HIF-1α via MAPK/PI3K pathways in hypoxic endothelial cells.

  2025cites this paper
• Advancements in Gene-Based Therapeutic Angiogenesis for Chronic Limb-Threatening Ischemia

  2025cites this paper
• Therapeutic Angiogenesis and Cardiovascular Disease: A Review.

  2024cites this paper
• Translational Relevance of Advanced Age and Atherosclerosis in Preclinical Trials of Biotherapies for Peripheral Artery Disease

  2024cites this paper
• Fibroblast Growth Factors in Cardiovascular Disease

  2024cites this paper
• Experimental Early Stimulation of Bone Tissue Neo-Formation for Critical Size Elimination Defects in the Maxillofacial Region

  2023cites this paper
• Therapeutic angiogenesis-based strategy for peripheral artery disease

  2022cites this paper
• Comparative Effects of Basic Fibroblast Growth Factor Delivery or Voluntary Exercise on Muscle Regeneration after Volumetric Muscle Loss

  2022cites this paper
• Effective treatment of intractable diseases using nanoparticles to interfere with vascular supply and angiogenic process

  2022cites this paper
• Pitavastatin-Incorporated Nanoparticles for Chronic Limb Threatening Ischemia: A Phase I/IIa Clinical Trial

  2021cites this paper
• Therapeutic Angiogenesis: Translational and Clinical Experience

  2020cites this paper
• Recruitment and Maturation of the Coronary Collateral Circulation: Current Understanding and Perspectives in Arteriogenesis.

  2020cites this paper
• Natural polymeric biomaterials in growth factor delivery for treating diabetic foot ulcers

  2020cites this paper
• Heparin-Hyaluronic Acid Nanofibers for Growth Factor Sequestration in Spinal Cord Repair.

  2020cites this paper
• Toward the Clinical Application of Therapeutic Angiogenesis Against Pediatric Ischemic Retinopathy

  2020cites this paper
• Local pharmacological induction of angiogenesis: Drugs for cells and cells as drugs.

  2019cites this paper
• Nitric Oxide and Hydrogen Sulfide Regulation of Ischemic Vascular Growth and Remodeling.

  2019cites this paper
• [Conservative treatment of chronic lower limb ischemia in ambulatory practice (in Russian only)].

  2019cites this paper
• Wachstumsfaktoren unter besonderer Berücksichtigung des muskuloskelettalen Systems

  2018cites this paper
• Non-viral Vector for Muscle-Mediated Gene Therapy

  2018cites this paper
• Application of polycaprolactone, chitosan, and collagen composite as a nanofibrous mat loaded with silver sulfadiazine and growth factors for wound dressing

  2018cites this paper
• Collagen/Heparin Bi-Affinity Multilayer Modified Collagen Scaffolds for Controlled bFGF Release to Improve Angiogenesis In Vivo.

  2018cites this paper
• Therapeutic Angiogenesis: Foundations and Practical Application

  2017cites this paper
• Growth factors for angiogenesis in peripheral arterial disease.

  2017cites this paper
• Collection of Serum- and Feeder-free Mouse Embryonic Stem Cell-conditioned Medium for a Cell-free Approach.

  2017cites this paper
• Controlled release of basic fibroblast growth factor for angiogenesis using acoustically-responsive scaffolds.

  2017cites this paper
• Pro-angiogenic effect of RANTES-loaded polysaccharide-based microparticles for a mouse ischemia therapy

  2017cites this paper
• FGF in Cardiovascular Disease

  2017cites this paper
• Fibroblast Growth Factor in Extremities

  2017cites this paper
• Angiogenesis in Peripheral Artery Disease: Focus on Growth Factor Therapy

  2016cites this paper
• The Roles of the High and Low Molecular Weight Isoforms of Fibroblast Growth Factor 2 in Ischemia-Induced Revascularization

  2016cites this paper
• Syndecan‐4 Enhances Therapeutic Angiogenesis after Hind Limb Ischemia in Mice with Type 2 Diabetes

  2016cites this paper
• Delivering therapeutics in peripheral artery disease: challenges and future perspectives.

  2016cites this paper
• The inflammatory role of angiogenic growth factors : a neutrophil perspective

  2015cites this paper
• Nanoscale strategies: treatment for peripheral vascular disease and critical limb ischemia.

  2015cites this paper
• Therapeutic Angiogenesis in Ischemic Tissues by Growth Factors and Bone Marrow Mononuclear Cells Administration: Biological Foundation and Clinical Prospects.

  2015cites this paper
• ТЕРАПЕВТИЧЕСКИЙ АНГИОГЕНЕЗ С ИСПОЛЬЗОВАНИЕМ ФАКТОРОВ РОСТА И КЛЕТОК КОСТНОГО МОЗГА: БИОЛОГИЧЕСКИЕ ОСНОВЫ И ПЕРСПЕКТИВЫ КЛИНИЧЕСКОГО ПРИМЕНЕНИЯ

  2015cites this paper
• Paracrine Factors Secreted by Umbilical Cord-Derived Mesenchymal Stem Cells Induce Angiogenesis In Vitro by a VEGF-Independent Pathway

  2015cites this paper
• Engineering Angiogenesis for Myocardial Infarction Repair: Recent Developments, Challenges, and Future Directions

  2014cites this paper
• Basic fibroblast growth factor reduces functional and structural damage in chronic kidney disease.

  2014cites this paper
• Uncoupling angiogenesis and inflammation in peripheral artery disease with therapeutic peptide-loaded microgels.

  2014cites this paper
• Therapeutic angiogenesis: recent and future prospects of gene therapy in peripheral artery disease.

  2014cites this paper
• An insight into the possibilities of fibroblast growth factor in periodontal regeneration

  2014cites this paper
• Engineering Angiogenesis for Myocardial Infarction Repair: Recent Developments, Challenges, and Future Directions

  2014cites this paper
• Therapeutic angiogenesis for revascularization in peripheral artery disease.

  2013cites this paper
• Peripheral Arterial Disease: Pathophysiology and Therapeutics

  2013cites this paper
• Gene Therapy for Peripheral Arterial Disease Using Sendai Virus Vector: From Preclinical Studies to the Phase I/IIa Clinical Trial

  2013cites this paper
• DVC1-0101 to treat peripheral arterial disease: a Phase I/IIa open-label dose-escalation clinical trial.

  2013cites this paper
• Stem Cell Microencapsulation for Therapeutic Angiogenesis

  2013cites this paper
• Effect of eicosapentaenoic acid on regional arterial stiffness: Assessment by tissue Doppler imaging.

  2012cites this paper
• Only time can tell: a commentary

  2012cites this paper
• Isquemia de Membros Inferiores: perspectiva atual da terapia celular e terapia gênica Lower Limb Ischemia: current outlook for cell therapy and gene therapy

  2012cites this paper
• A Computational Model of Fibroblast Growth Factor-2 Binding to Endothelial Cells Under Fluid Flow

  2012cites this paper
• Combined Transplantation of Bone Marrow Stromal Cell-Derived Neural Progenitor Cells with a Collagen Sponge and Basic Fibroblast Growth Factor Releasing Microspheres Enhances Recovery After Cerebral Ischemia in Rats

  2011cites this paper
• Autologous Bone-Marrow Mononuclear Cell Implantation Reduces Long-Term Major Amputation Risk in Patients With Critical Limb Ischemia: A Comparison of Atherosclerotic Peripheral Arterial Disease and Buerger Disease

  2011cites this paper
• A system for treating ischemic disease using human embryonic stem cell-derived endothelial cells without direct incorporation.

  2011cites this paper
• Gene therapy for vascular disease

  2011cites this paper
• Memory of fearful events: the role of fibroblast growth factor-2 in fear acquisition and extinction.

  2011cites this paper
• Noninvasive transdermal iontophoretic delivery of biologically active human basic fibroblast growth factor.

  2011cites this paper
• Therapeutische Angiogenese bei PAVK - quo vadis?

  2011cites this paper
• Pharmacological enhancement of fear reduction: preclinical models

  2011cites this paper
• Stem cell therapy for peripheral arterial disease: a review of clinical trials

  2011cites this paper
• Gene Therapy for Therapeutic Angiogenesis

  2011cites this paper
• Periodontal tissue regeneration by signaling molecule(s): what role does basic fibroblast growth factor (FGF-2) have in periodontal therapy?

  2011cites this paper
• Intramarrow bone morphogenetic protein 4 gene delivery improves local bone quality in femurs of ovariectomized rabbits.

  2011cites this paper
• Controlled-Release Basic Fibroblast Growth Factor for Peripheral Artery Disease: Comparison with Autologous Bone Marrow-Derived Stem Cell Transfer

  2011cites this paper
• Increased perfusion and angiogenesis in a hindlimb ischemia model with plasmid FGF-2 delivered by noninvasive electroporation

  2010cites this paper
• Mise à jour sur l’angiogenèse thérapeutique dans la maladie vasculaire périphérique

  2010cites this paper
• An update on therapeutic angiogenesis for peripheral vascular disease.

  2010cites this paper
• 4) Prospects of Revascularization Therapy.

  2010cites this paper
• DNA electrotransfer to the skin: a highly translatable approach to treat peripheral artery disease

  2010cites this paper
• The FGF family: biology, pathophysiology and therapy

  2009cites this paper
• Basic fibroblast growth factor increases intracellular magnesium concentration through the specific signaling pathways

  2009cites this paper
• Meta-analysis of randomized, controlled clinical trials in angiogenesis: gene and cell therapy in peripheral arterial disease

  2009cites this paper
• Current management of intermittent claudication: the role of pharmacological and nonpharmacological symptom-directed therapies.

  2009cites this paper
• Novel Cell-Free Strategy for Therapeutic Angiogenesis: In Vitro Generated Conditioned Medium Can Replace Progenitor Cell Transplantation

  2009cites this paper
• Effects of basic fibroblast growth factor‐2 and hyaluronic acid on tracheal wound healing

  2009cites this paper
• Accelerated wound closure of pressure ulcers in aged mice by chitosan scaffolds with and without bFGF.

  2009cites this paper
• Vascular regeneration by repeated infusions of basic fibroblast growth factor in a rabbit model of hind-limb ischemia.

  2009cites this paper
• Selective and sustained delivery of basic fibroblast growth factor (bFGF) for treatment of peripheral arterial disease: results of a phase I trial.

  2009cites this paper
• [Mechanisms and potential of the therapeutic stimulation of arteriogenesis].

  2009cites this paper
• chapter 8 – Natural History and Medical Management of Chronic Lower Extremity Ischemia

  2009cites this paper
• Intradermal delivery of plasmids encoding angiogenic growth factors by electroporation promotes wound healing and neovascularization

  2009cites this paper
• Zytokinbeschichtete Stents als neue Werkzeuge der angiogenen Therapie

  2008cites this paper
• Effects of Basic Fibroblast Growth Factor Administration on Vascular Changes in Wound Healing of Rat Palates

  2008cites this paper
• Losordo of Age Therapeutic Angiogenesis for Critical Limb Ischemia : Microvascular Therapies Coming

  2008cites this paper
• International Olympic Committee consensus statement: molecular basis of connective tissue and muscle injuries in sport.

  2008cites this paper
• Role of vascular endothelial growth factor-A in collateral growth and development

  2008cites this paper
• Mass transfer in porous tissue engineering scaffolds

  2008cites this paper
• Engineering the Microcirculation

  2008cites this paper
• Vascular Effects of FGF-2 and VEGF-B in Rabbits with Bilateral Hind Limb Ischemia

  2008cites this paper
• Enhanced perigraft angiogenesis prevents prosthetic graft infection.

  2008cites this paper
• Gene and stem cell therapy in peripheral arterial occlusive disease

  2008cites this paper
• Advances in treating the ischaemic diabetic foot.

  2008cites this paper
• Increased antiangiogenic protein expression in the skeletal muscle of diabetic swine and patients.

  2008cites this paper
• Muscular gene transfer using nonviral vectors.

  2008cites this paper
• Therapeutic angiogenesis for critical limb ischemia: microvascular therapies coming of age.

  2008cites this paper
• Arteriogenesis: basic mechanisms and therapeutic stimulation

  2007cites this paper