Psychoneuroendocrinological contributions to the etiology of depression, posttraumatic stress disorder, and stress-related bodily disorders: the role of the hypothalamus-pituitary-adrenal axis.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Biological Psychology

• Publication date

  2001-08-01

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1016/S0301-0511(01)00092-8PMID 11454437
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Low-Dose Dexamethasone Suppression Test in Chronic Fatigue Syndrome and Health

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  2002cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
• Pharmakologische Provokationstests zur Einschätzung der neuroendokrinen Funktion

  1999cited by this paper
• Chronic Pelvic Pain as a Somatoform Disorder

  1999cited by this paper
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  1999cited by this paper
• Case of chronic fatigue syndrome after Crimean war and Indian mutiny

  1999cited by this paper
• Salivary cortisol and serum prolactin in relation to stress rating scales in a group of rescue workers.

  1999influential reference
• The dexamethasone‐suppressed corticotrophin‐releasing hormone stimulation test in anorexia nervosa

  1999cited by this paper
• Burnout, perceived stress, and cortisol responses to awakening.

  1999cited by this paper
• Small adrenal glands in chronic fatigue syndrome: a preliminary computer tomography study.

  1999cited by this paper
• Psychological Stress and Neuroendocrine Function in Humans: The Last Two Decades of Research

  1999cited by this paper
• Critical life events, infections, and symptoms during the year preceding chronic fatigue syndrome (CFS): an examination of CFS patients and subjects with a nonspecific life crisis.

  1999influential reference
• Abuse-Related Posttraumatic Stress Disorder and Alterations of the Hypothalamic-Pituitary-Adrenal Axis in Women With Chronic Pelvic Pain

  1998cited by this paper
• Urinary free cortisol excretion in chronic fatigue syndrome, major depression and in healthy volunteers.

  1998cited by this paper
• Blunted adrenocorticotropin and Cortisol responses to corticotropin‐releasing hormone stimulation in chronic fatigue syndrome

  1998cited by this paper
• A healthy body in a healthy mind--and vice versa--the damaging power of "uncontrollable" stress.

  1998influential reference
• Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder.

  1997cited by this paper
• The corticotropin-releasing hormone challenge in depressed abused, depressed nonabused, and normal control children.

  1997cited by this paper
• Salivary Cortisol Profiles in Chronic Fatigue Syndrome

  1997cited by this paper
• Precipitating factors for the chronic fatigue syndrome.

  1997influential reference
• Enhanced dexamethasone suppression of plasma cortisol in adult women traumatized by childhood sexual abuse.

  1997influential reference
• Sensitization of the Hypothalamic‐Pituitary‐Adrenal Axis in Posttraumatic Stress Disorder a

  1997cited by this paper
• A low dose ACTH test to assess the function of the hypothalamic–pituitary–adrenal axis

  1996cited by this paper
• Basal cortisol, dexamethasone suppression of cortisol, and MHPG in adolescents after the 1988 earthquake in Armenia.

  1996cited by this paper
• Stress hormones in accident patients studied before admission to hospital.

  1996cited by this paper
• Stages of decompensation in combat-related posttraumatic stress disorder: A new conceptual model

  1996cited by this paper
• The effects of chronic industrial noise exposure on urinary cortisol, fatigue and irritability: a controlled field experiment.

  1996cited by this paper
• Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids.

  1996cited by this paper
• Effect of Chronic Stress Associated With Unemployment on Salivary Cortisol: Overall Cortisol Levels, Diurnal Rhythm, and Acute Stress Reactivity

  1995cited by this paper
• The effects of alcoholism on the hypothalamic‐pituitary‐adrenal axis: interaction with endogenous opioid peptides

  1995cited by this paper
• Corticotropin Releasing Hormone in the Pathophysiology of Melancholic and Atypical Depression and in the Mechanism of Action of Antidepressant Drugs

  1995cited by this paper
• Posttraumatic stress disorder in the National Comorbidity Survey.

  1995cited by this paper
• Low urinary cortisol excretion in Holocaust survivors with posttraumatic stress disorder.

  1995cited by this paper
• Corticotropin-releasing factor receptors: physiology, pharmacology, biochemistry and role in central nervous system and immune disorders.

  1995influential reference
• Effect of previous trauma on acute plasma cortisol level following rape.

  1995cited by this paper
• Abuse-Related Posttraumatic Stress Disorder: Evidence for Chronic Neuroendocrine Activation in Women

  1995cited by this paper
• Circadian Regulation of Basal Cortisol Levels in Posttraumatic Stress Disorder

  1994cited by this paper
• Psychoendokrinologische Untersuchung an Patientinnen mit chronischen Unterbauchbeschwerden

  1994cited by this paper
• Diagnostic and Statistical Manual of Mental Disorders, 4th Ed.

  1994cited by this paper
• Exercise-induced activation of the hypothalamic-pituitary-adrenal axis: marked differences in the sensitivity to glucocorticoid suppression.

  1994cited by this paper
• Hypothalamic-pituitary-adrenal axis dysregulation in sexually abused girls.

  1994cited by this paper
• Depressed concentrations of oxytocin and cortisol in children with recurrent abdominal pain of non‐organic origin

  1994cited by this paper
• Low urinary cortisol excretion in holocaust survivors with posttraumatic stress disorder

  1994influential reference
• The Chronic Fatigue Syndrome: A Comprehensive Approach to Its Definition and Study

  1994cited by this paper
• The combined dexamethasone/CRH test: a refined laboratory test for psychiatric disorders.

  1994influential reference
• Implications of psychological research on stress and technological accidents.

  1993cited by this paper
• The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis.

  1992cited by this paper
• Corticotropin-releasing hormone in humans.

  1992cited by this paper
• Evidence for impaired activation of the hypothalamic-pituitary-adrenal axis in patients with chronic fatigue syndrome.

  1991cited by this paper
• Neuroendocrine and immunologic effects of unemployment and job insecurity.

  1991cited by this paper
• Hormonal changes in headache patients.

  1991cited by this paper
• Hormonal responses of pilots flying high-performance aircraft during seven repetitive flight missions.

  1991cited by this paper
• The dexamethasone suppression test and thyrotropin-releasing hormone stimulation test in posttraumatic stress disorder.

  1990cited by this paper
• Low Urinary Cortisol Excretion in Patients with Posttraumatic Stress Disorder

  1990cited by this paper
• Neuroendocrine response to fenfluramine in patients with idiopathic pain syndromes

  1989cited by this paper
• The corticotropin-releasing hormone test in patients with posttraumatic stress disorder.

  1989cited by this paper
• Psychogenic pain and depressive disorders: an empirical study.

  1989cited by this paper
• Clinical and biochemical manifestations of depression. Relation to the neurobiology of stress (2)

  1988cited by this paper
• Reduced corticotropin releasing factor binding sites in the frontal cortex of suicide victims.

  1988cited by this paper
• Delta sleep-inducing peptide response to human corticotropin-releasing hormone (CRH) in major depressive disorder. Comparison with CRH-induced corticotropin and cortisol secretion.

  1988cited by this paper
• Long-term unemployment among women in Sweden.

  1987cited by this paper
• Endocrine and neurophysiologic responses of the pituitary to insulin-induced hypoglycemia: a review.

  1986cited by this paper
• Textbook of clinical chemistry

  1986cited by this paper
• Abnormal hypothalamic-pituitary-adrenal function in anorexia nervosa. Pathophysiologic mechanisms in underweight and weight-corrected patients.

  1986cited by this paper
• Textbook of Clinical Chemistry

  1986cited by this paper
• Urinary Free-Cortisol Levels in Posttraumatic Stress Disorder Patients

  1986cited by this paper
• Stress, Appraisal, and Coping. New York, NY: Springer;

  1984cited by this paper
• Elevated concentrations of CSF corticotropin-releasing factor-like immunoreactivity in depressed patients.

  1984cited by this paper
• Psychosomatische Probleme in der Gynäkologie und Geburtshilfe

  1984cited by this paper
• Endocrine activity in air traffic controllers at work. I. Characterization of cortisol and growth hormone levels during the day.

  1982cited by this paper
• Differences in serum cortisol concentrations in organic and psychogenic chronic pain syndromes.

  1982cited by this paper
• Endocrine activity in air traffic controllers at work. III. Relationship to physical and psychiatric morbidity.

  1982cited by this paper
• Endocrine activity in air traffic controllers at work

  1982cited by this paper
• Endocrine activity in air traffic controllers at work. II. Biological, psychological and work correlates.

  1982cited by this paper
• A specific laboratory test for the diagnosis of melancholia. Standardization, validation, and clinical utility.

  1981cited by this paper
• White collar work load and cortisol: disruption of a circadian rhythm by job stress?

  1979cited by this paper
• Stress levels of ambulance paramedics and fire fighters.

  1978cited by this paper
• A Review of Psychoendocrine Research on the Pituitary‐Adrenal Cortical System

  1968cited by this paper
• Depressive affect and endocrine functions; blood levels of adrenal cortex and thyroid hormones in patients suffering from depressive reactions.

  1957cited by this paper
• Stress of Life

  1956cited by this paper
• THE EMERGENCY FUNCTION OF THE ADRENAL MEDULLA IN PAIN AND THE MAJOR EMOTIONS

  1914cited by this paper

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