Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2008-06-10

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/pnas.0800334105PMID 18524951PMCID PMC2430345
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells.

  2008cited by this paper
• Noncoding RNAs and gene silencing.

  2007cited by this paper
• The Piwi-piRNA Pathway Provides an Adaptive Defense in the Transposon Arms Race

  2007cited by this paper
• Gene silencing mechanisms mediated by Aubergine piRNA complexes in Drosophila male gonad.

  2007cited by this paper
• A Slicer-Mediated Mechanism for Repeat-Associated siRNA 5' End Formation in Drosophila

  2007cited by this paper
• A mammalian microRNA expression atlas based on small RNA library sequencing.

  2007cited by this paper
• Identification of Human microRNA Targets From Isolated Argonaute Protein Complexes

  2007cited by this paper
• A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway.

  2007cited by this paper
• Structural features of small RNA precursors determine Argonaute loading in Caenorhabditis elegans

  2007cited by this paper
• A Model for Initiation of Mosaic HOX Gene Expression Patterns by Non-Coding RNAs in Early Embryos

  2007cited by this paper
• Argonaute proteins: mediators of RNA silencing.

  2007influential reference
• microRNA functions.

  2007cited by this paper
• Mighty Piwis defend the germline against genome intruders.

  2007cited by this paper
• Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome.

  2006cited by this paper
• Cleavage of the siRNA passenger strand during RISC assembly in human cells

  2006influential reference
• The diverse functions of microRNAs in animal development and disease.

  2006cited by this paper
• Inhibition of Translational Initiation by Let-7 MicroRNA in Human Cells

  2005cited by this paper
• Slicer function of Drosophila Argonautes and its involvement in RISC formation.

  2005cited by this paper
• MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

  2005cited by this paper
• Perspective: machines for RNAi.

  2005cited by this paper
• Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes.

  2005influential reference
• Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping.

  2005cited by this paper
• Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies

  2005cited by this paper
• Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs.

  2004influential reference
• Argonaute2 Is the Catalytic Engine of Mammalian RNAi

  2004influential reference
• Prediction of mammalian microRNA targets.

  2003cited by this paper
• miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs.

  2002cited by this paper
• RNA interference is mediated by 21- and 22-nucleotide RNAs.

  2001cited by this paper
• E1B 55-Kilodalton-Associated Protein: a Cellular Protein with RNA-Binding Activity Implicated in Nucleocytoplasmic Transport of Adenovirus and Cellular mRNAs

  1998cited by this paper
• A nuclear localization domain in the hnRNP A1 protein

  1995cited by this paper
• Leading Edge Review Noncoding RNAs and Gene Silencing

  year unknowncited by this paper
• References and Notes Materials and Methods Som Text Fig. S1 Table S1 References a Microrna in a Multiple- Turnover Rnai Enzyme Complex

  year unknowncited by this paper

• SARS-CoV-2-Derived RNA Fragment Induces Myocardial Dysfunction via siRNA-like Suppression of Mitochondrial ATP Synthase

  2025cites this paper
• Pharmaceutical perspectives on oligonucleotide therapeutics and delivery systems.

  2025cites this paper
• Mapping effective microRNA pairing beyond the seed using abasic modifications

  2025cites this paper
• Temporal Dynamics of tsRNA Regulation Mark an Abrupt Transition After Epileptogenesis

  2025cites this paper
• Regulatory role of RNA-binding proteins in microRNA biogenesis

  2024cites this paper
• Novel de Novo Nonsense Variants in AGO3 and KHSRP: Insights into Global Developmental Delay and Autism Spectrum Disorders through Whole Genome Analysis

  2024cites this paper
• Age and 17β-Estradiol (E2) Facilitate Nuclear Export and Argonaute Loading of microRNAs in the Female Brain

  2023cites this paper
• One locus, several functional RNAs—emerging roles of the mechanisms responsible for the sequence variability of microRNAs

  2023cites this paper
• Efficient 3′-pairing renders microRNA targeting less sensitive to mRNA seed accessibility

  2023cites this paper
• Utilizing functional cell‐free extracts to dissect ribonucleoprotein complex biology at single‐molecule resolution

  2023cites this paper
• A Proposed Role for Interactions between Argonautes, miRISC, and RNA Binding Proteins in the Regulation of Local Translation in Neurons and Glia

  2022cites this paper
• Single-molecule imaging of microRNA-mediated gene silencing in cells

  2022cites this paper
• The piRNAs present in the developing testes of Chinese indigenous Xiang pigs.

  2022cites this paper
• Anatomy of four human Argonaute proteins

  2022cites this paper
• Keeping development on time: Insights into post‐transcriptional mechanisms driving oscillatory gene expression during vertebrate segmentation

  2022cites this paper
• Functional Discovery of Small Non-coding RNA Through Computational Inference

  2021cites this paper
• Life of RISC: Formation, action, and degradation of RNA-induced silencing complex.

  2021cites this paper
• Single-molecule imaging of microRNA-mediated gene silencing in cells

  2021cites this paper
• Vznik a význam sekvenčních variant

  2021cites this paper
• Novel approaches in cancer treatment: preclinical and clinical development of small non-coding RNA therapeutics

  2021cites this paper
• OBSOLETE: Functional Discovery of Small Non-coding RNA Through Computational Inference

  2020cites this paper
• RNAi and miRNA pathways in mammals I – molecular mechanisms

  2020cites this paper
• An alternative miRISC targeting a coding mutation site in FOXL2 links to granulosa cell tumor

  2020cites this paper
• Non-Templated Oligo-Adenylation of Small RNAs in the Parasite Entamoeba: Potential Roles for Small RNA Control in Single Celled Eukaryotic Pathogen

  2020cites this paper
• Identification of oligo-adenylated small RNAs in the parasite Entamoeba and a potential role for small RNA control

  2020cites this paper
• An alternative miRISC targets a cancer‐associated coding sequence mutation in FOXL2

  2020cites this paper
• A Requirement for Argonaute 4 in Mammalian Antiviral Defense

  2020cites this paper
• Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection: let the virus be its own demise

  2020cites this paper
• Identification of microRNAs for regulating adenosine monophosphate‐activated protein kinase expression in immature boar Sertoli cells in vitro

  2019cites this paper
• A survey of software tools for microRNA discovery and characterization using RNA-seq

  2019cites this paper
• MicroRNAs in Daphnia magna identified and characterized by deep sequencing, genome mapping and manual curation

  2019cites this paper
• No evidence for viral small RNA production and antiviral function of Argonaute 2 in human cells

  2019cites this paper
• Identification and Validation of Leaf Rust Responsive Wheat isomiRs and their Target Genes in both Wheat and Puccinia triticina

  2019cites this paper
• Multidomain Convergence of Argonaute during RISC Assembly Correlates with the Formation of Internal Water Clusters.

  2019cites this paper
• MicroRNAs in Gametes and Preimplantation Embryos: Clinical Implications

  2019cites this paper
• Hidden sequence specificity in loading of single-stranded RNAs onto Drosophila Argonautes

  2018cites this paper
• MicroRNAs in depression and suicide: Recent insights and future perspectives.

  2018cites this paper
• A Comprehensive Approach to Sequence-oriented IsomiR annotation (CASMIR): demonstration with IsomiR profiling in colorectal neoplasia

  2018cites this paper
• P-Bodies: Cytosolic Droplets for Coordinated mRNA Storage.

  2018cites this paper
• Dual Strategies for Argonaute2-Mediated Biogenesis of Erythroid miRNAs Underlie Conserved Requirements for Slicing in Mammals.

  2018cites this paper
• The role of miRNAs in mouse embryonic stem cells : a proteomics approach

  2018cites this paper
• Investigations of LIMD1 in miRNA-mediated gene silencing and cancers

  2018cites this paper
• Signature miRNAs in peripheral blood monocytes of patients with gastric or breast cancers

  2018cites this paper
• MicroRNA-mediated immune regulation in rheumatic diseases.

  2018cites this paper
• Do erythrocytic miRNA have a function

  2018cites this paper
• Clinical potential of oligonucleotide-based therapeutics in the respiratory system.

  2017cites this paper
• Characterizing isomiR variants within the microRNA‐34/449 family

  2017cites this paper
• Naturally existing isoforms of miR-222 have distinct functions

  2017cites this paper
• Shedding light on miRNA targeting through structure

  2017cites this paper
• THE PLASTICITY OF MIRNA POOL: A NOVEL APPROACH TO REVEAL MECHANISMS BEHIND MIRNA TURNOVER

  2017cites this paper
• A Review on Micro RNAs and its Application in Psoriasis

  2017cites this paper
• The Small Noncoding RNA Processing Machinery of Two Living Fossil Species, Lungfish and Coelacanth, Gives New Insights into the Evolution of the Argonaute Protein Family

  2017cites this paper
• Literature review of baseline information to support the risk assessment of RNAi‐based GM plants

  2017cites this paper
• Dicer-independent processing of small RNA duplexes: mechanistic insights and applications

  2017cites this paper
• RNA immunoprecipitation technique for Drosophila melanogaster S2 cells

  2017cites this paper
• Title Argonaute identity defines the length of maturemammalian microRNAs

  2017cites this paper
• Interactome of TNRC6 W-motifs and their conserved Role in miRNA-mediated silencing

  2017cites this paper
• Differential expression of small RNA pathway genes associated with the Biomphalaria glabrata/Schistosoma mansoni interaction

  2017cites this paper
• Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects

  2017influential citation
• A promoter-proximal transcript targeted by genetic polymorphism controls E-cadherin silencing in human cancers

  2017cites this paper
• The roles of SH2-containing inositol 5'-phosphatase 1 (SHIP1) and signal transducer and activator of transcription 3 (STAT3) in interleukin-10 regulation of activated macrophages

  2016cites this paper
• A non-coding RNA network influenced by genetic polymorphism controls E-cadherin expression in human cancers

  2016cites this paper
• Identification and characterization of novel and conserved microRNAs in several tissues of the Chinese rare minnow (Gobiocypris rarus) based on illumina deep sequencing technology

  2016cites this paper
• Interactions des microARN de la famille miR-34/449 avec les voies de signalisation intracellulaire : rôle dans la différenciation des cellules multiciliées chez les vertébrés

  2016cites this paper
• Detection of miRNA in Cultured Cells or Xenograft Tissues of Breast Cancer.

  2016cites this paper
• Modern Transcriptomics and Small RNA Diversity

  2016cites this paper
• Expression Profile of microRNAs and Their Targeted Pathways in Human Ovaries Detected by Next-Generation Small RNA Sequencing

  2016influential citation
• Anatomy of RISC: how do small RNAs and chaperones activate Argonaute proteins?

  2016cites this paper
• Unraveling the Mysterious Interactions Between Hepatitis C Virus RNA and Liver-Specific MicroRNA-122.

  2016cites this paper
• Cell‐free microRNAs in blood and other body fluids, as cancer biomarkers

  2016cites this paper
• Intracellular and extracellular microRNA: An update on localization and biological role.

  2016cites this paper
• Dynamics of mRNA and microRNA expression in the estrogen response of breast cancer cells

  2016cites this paper
• Caractérisation structurale et fonctionnelle d’une nouvelle interaction entre les protéines RPAP3 et TRBP

  2016cites this paper
• MicroRNAs and Cardiac Regeneration.

  2015cites this paper
• Uncovering Direct Targets of MiR-19a Involved in Lung Cancer Progression

  2015cites this paper
• Slicer-independent mechanism drives small-RNA strand separation during human RISC assembly

  2015cites this paper
• Design and characterization of new classes of antagonists targeting the Lin28/let-7 interaction

  2015cites this paper
• Predicting effective microRNA target sites in mammalian mRNAs

  2015cites this paper
• Markov State Models Reveal a Two-Step Mechanism of miRNA Loading into the Human Argonaute Protein: Selective Binding followed by Structural Re-arrangement

  2015cites this paper
• Variability of miRNA expression during the differentiation of human embryonic stem cells into retinal pigment epithelial cells.

  2015cites this paper
• Single-Molecule Imaging Reveals that Argonaute Re-Shapes the Properties of its Nucleic Acid Guides: A Dissertation

  2015cites this paper
• Divergent target recognition by coexpressed 5′-isomiRs of miR-142-3p and selective viral mimicry

  2015influential citation
• MicroRNAs in Tissue Engineering and Regenerative Medicine

  2015cites this paper
• Exosomes from bulk and stem cells from human prostate cancer have a differential microRNA content that contributes cooperatively over local and pre-metastatic niche

  2015cites this paper
• MicroRNA Biogenesis in Regenerative Medicine

  2015cites this paper
• Temporal patterns of short non-coding RNA modifications and expression

  2015cites this paper
• G‐quadruplexes: Emerging roles in neurodegenerative diseases and the non‐coding transcriptome

  2015cites this paper
• The role of microRNAs in thyroid carcinomas.

  2015cites this paper
• Characterization of the mammalian miRNA turnover landscape

  2015cites this paper
• Dengue virus infection alters post-transcriptional modification of microRNAs in the mosquito vector Aedes aegypti

  2015cites this paper
• Biogenesis and regulation of the let-7 miRNAs and their functional implications

  2015cites this paper
• Role of microRNAs in cancers of the female reproductive tract: insights from recent clinical and experimental discovery studies.

  2015cites this paper
• Characterization of microRNA profile in human cumulus granulosa cells: Identification of microRNAs that regulate Notch signaling and are associated with PCOS.

  2015cites this paper
• Aberrant microRNA expression in spinal muscular atrophy motor neurons

  2015cites this paper
• FANG: bi-shRNAifurin and GMCSF DNA-Augmented Autologous Tumor Cell Vaccine: Clinical Results

  2015cites this paper
• Small RNA Sequencing Uncovers New miRNAs and moRNAs Differentially Expressed in Normal and Primary Myelofibrosis CD34+ Cells

  2015cites this paper
• The characteristics of the porcine (Sus scrofa) liver miRNAome with the use of next generation sequencing

  2015cites this paper
• tRNA-Derived Short Non-coding RNA as Interacting Partners of Argonaute Proteins

  2015cites this paper
• Dumbbell-PCR: a method to quantify specific small RNA variants with a single nucleotide resolution at terminal sequences

  2015cites this paper
• Impact of age-associated increase in 2′-O-methylation of miRNAs on aging and neurodegeneration in Drosophila

  2014cites this paper