CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Cell

• Publication date

  2001-01-12

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0092-8674(01)00190-8PMID 11163239
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• [Caenorhabditis elegans].

  2020influential reference
• ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine.

  2000cited by this paper
• A receptor for phosphatidylserine-specific clearance of apoptotic cells

  2000cited by this paper
• AN APPETITE FOR APOPTOTIC CELLS? CONTROVERSIES AND CHALLENGES

  2000cited by this paper
• CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans

  2000cited by this paper
• Cell death in development.

  1999cited by this paper
• Phosphatidylserine Receptors: Role of CD36 in Binding of Anionic Phospholipid Vesicles to Monocytic Cells*

  1999cited by this paper
• Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.

  1999cited by this paper
• Requirement for croquemort in phagocytosis of apoptotic cells in Drosophila.

  1999cited by this paper
• Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice.

  1999cited by this paper
• The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene.

  1999cited by this paper
• Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline.

  1999influential reference
• Ultrastructural features of the adult hermaphrodite gonad of Caenorhabditis elegans: relations between the germ line and soma.

  1999cited by this paper
• Signaling pathways in phagocytosis

  1999cited by this paper
• Lectin-like oxidized low-density lipoprotein receptor 1 mediates phagocytosis of aged/apoptotic cells in endothelial cells.

  1998cited by this paper
• Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans.

  1998cited by this paper
• The C. elegans cell corpse engulfment gene ced-7 encodes a protein similar to ABC transporters.

  1998influential reference
• Notch/LIN-12 signaling: transduction by regulated protein slicing.

  1998cited by this paper
• Genome sequence of the nematode C. elegans: a platform for investigating biology.

  1998cited by this paper
• Regulated nuclear import of Rel proteins in the Drosophila immune response

  1998cited by this paper
• Genome sequence of the nematode C-elegans: A platform for investigating biology

  1998cited by this paper
• C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180

  1998influential reference
• C. Elegans II

  1998cited by this paper
• The role of phosphatidylserine in recognition of apoptotic cells by phagocytes

  1998cited by this paper
• Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.

  1998cited by this paper
• Recognizing death: the phagocytosis of apoptotic cells.

  1998cited by this paper
• Genetics of programmed cell death in C. elegans: past, present and future.

  1998cited by this paper
• Signaling through scaffold, anchoring, and adaptor proteins.

  1997influential reference
• Characterization of CLA-1, a Human Homologue of Rodent Scavenger Receptor BI, as a Receptor for High Density Lipoprotein and Apoptotic Thymocytes*

  1997cited by this paper
• Expression Cloning of a Novel Scavenger Receptor from Human Endothelial Cells*

  1997influential reference
• Rho GTPases and signaling networks.

  1997cited by this paper
• The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation.

  1997cited by this paper
• [Genetic control of programmed cell death].

  1996cited by this paper
• Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro.

  1996cited by this paper
• CD36 gene transfer confers capacity for phagocytosis of cells undergoing apoptosis

  1995cited by this paper
• Recognition and specificity in protein tyrosine kinase-mediated signalling.

  1995cited by this paper
• Green fluorescent protein as a marker for gene expression.

  1994cited by this paper
• Structures and Functions of Multiligand and Lipoprotein Receptors

  1994cited by this paper
• Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP).

  1994cited by this paper
• Epidermal growth factor-like modules

  1993influential reference
• Phagocyte recognition of cells undergoing apoptosis.

  1993cited by this paper
• Temporal and spatial expression patterns of the small heat shock (hsp16) genes in transgenic Caenorhabditis elegans.

  1992cited by this paper
• Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans.

  1991influential reference
• Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences.

  1991cited by this paper
• [Genetics of Caenorhabditis elegans].

  1989cited by this paper
• Biochemistry. 3rd edition

  1988cited by this paper
• A trans-spliced leader sequence on actin mRNA in C. elegans

  1987cited by this paper
• Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans.

  1983cited by this paper
• The embryonic cell lineage of the nematode Caenorhabditis elegans.

  1983cited by this paper
• A simple method for displaying the hydropathic character of a protein.

  1982cited by this paper
• Morphology of programmed cell death in the ventral nerve cord of Caenorhabditis elegans larvae

  1982influential reference
• Cell death: the significance of apoptosis.

  1980cited by this paper
• Where is the ?c?

  1978cited by this paper
• Post-embryonic cell lineages of the nematode, Caenorhabditis elegans.

  1977cited by this paper
• The genetics of Caenorhabditis elegans.

  1974cited by this paper

• Roles of Glia in Synapse Nano-organization.

  2026cites this paper
• Neuropeptide INS-14 modulates apoptotic cell clearance in Caenorhabditis elegans.

  2026cites this paper
• Paclitaxel-induced germline DNA-damage signatures independent of mismatch repair in C. elegans.

  2026cites this paper
• The synapsis checkpoint and the LIN-35/DREAM complex promote temperature stress-induced increases in germline apoptosis in Caenorhabditis elegans

  2025cites this paper
• Cell death in regeneration and cell turnover: Lessons from planarians and Drosophila.

  2025cites this paper
• C. elegans CED-1 acts in neurons to modulate ciliary protein abundance and extracellular vesicle shedding

  2025cites this paper
• Glia control experience-dependent plasticity in an olfactory critical period

  2025cites this paper
• DHHC-1-dependent modulation of CED-1 protein stability regulates apoptotic cell clearance in C. elegans.

  2025cites this paper
• Thiostrepton induces apoptotic cell death at the level of BCL-2/CED-9 in C. elegans

  2025cites this paper
• The lim-7p::ced-1::GFP transgene from the MD701 strain increases embryonic lethality in C. elegans

  2025cites this paper
• Depletion of tryptophanyl-tRNA synthetase and tryptophan accumulation triggers p53-dependent apoptosis

  2025influential citation
• Nutritional vitamin B12 regulates RAS/MAPK-mediated cell fate decisions through one-carbon metabolism

  2024cites this paper
• Glia control experience-dependent plasticity in an olfactory critical period

  2024cites this paper
• RNA is a pro-apoptotic target of cisplatin in cancer cell lines and C. elegans.

  2024cites this paper
• Involvement of β-glucan receptors on the antitumor activity of β-glucans

  2024cites this paper
• Vacuolar H+-ATPase determines daughter cell fates through asymmetric segregation of the nucleosome remodeling and deacetylase complex

  2024cites this paper
• The N terminus-only (trans) function of the adhesion G protein-coupled receptor latrophilin-1 controls multiple processes in reproduction of Caenorhabditis elegans

  2024cites this paper
• Astrocyte Regulation of Synapse Formation, Maturation, and Elimination.

  2024cites this paper
• SMC-5/6 complex subunit NSE-1 plays a crucial role in meiosis and DNA repair in Caenorhabditis elegans.

  2024cites this paper
• Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans

  2024cites this paper
• PemB, a type III secretion effector in Pseudomonas aeruginosa, affects Caenorhabditis elegans life span

  2024cites this paper
• Integrating evolutionarily conserved mechanism of response to radiation for exploring novel Caenorhabditis elegans radiation-responsive genes for estimation of radiation dose associated with spaceflight.

  2024cites this paper
• Planarians require ced-12/elmo-1 to clear dead cells by excretion through the gut.

  2024cites this paper
• Apoptotic and Nonapoptotic Cell Death in Caenorhabditis elegans Development.

  2024cites this paper
• Actomyosin-mediated apical constriction promotes physiological germ cell death in C. elegans

  2024cites this paper
• Polymer chain extenders induce significant toxicity through DAF-16 and SKN-1 pathways in Caenorhabditis elegans: A comparative analysis.

  2024cites this paper
• Drosophila glial system: an approach towards understanding molecular complexity of neurodegenerative diseases

  2024cites this paper
• Current evidence of synaptic dysfunction after stroke: Cellular and molecular mechanisms

  2024cites this paper
• Galectins induced from hemocytes bridge phosphatidylserine and N-glycosylated Drpr/CED-1 receptor during dendrite pruning

  2024cites this paper
• CED-6/GULP and components of the clathrin-mediated endocytosis machinery act redundantly to correctly display CED-1 on the cell membrane in Caenorhabditis elegans

  2024cites this paper
• Role of Microglia in Central Nervous System Development and Plasticity.

  2024cites this paper
• Xeroderma pigmentosum protein XPD controls caspase-mediated stress responses

  2024cites this paper
• Neurons dispose of hyperactive kinesin into glial cells for clearance

  2024cites this paper
• Non-autonomous insulin signaling delays mitotic progression in C. elegans germline stem and progenitor cells

  2024cites this paper
• Nanoplastic at environmentally relevant concentrations induces toxicity across multiple generations associated with inhibition in germline G protein-coupled receptor CED-1 in Caenorhabditis elegans.

  2024cites this paper
• CED-5/CED-12 (DOCK/ELMO) can promote and inhibit F-actin formation via distinct motifs that may target different GTPases

  2024cites this paper
• Methionine Supplementation Alleviates the Germ Cell Apoptosis Increased by Maternal Caffeine Intake in a C. elegans Model

  2024cites this paper
• Phagocytosis-driven neurodegeneration through opposing roles of an ABC transporter in neurons and phagocytes

  2024cites this paper
• Visualizing Phagocytic Cargo In Vivo from Engulfment to Resolution in Caenorhabditis elegans.

  2023cites this paper
• Long-term exposure to 6-PPD quinone reduces reproductive capacity by enhancing germline apoptosis associated with activation of both DNA damage and cell corpse engulfment in Caenorhabditis elegans.

  2023cites this paper
• Early Draper-mediated glial refinement of neuropil architecture and synapse number in the Drosophila antennal lobe

  2023cites this paper
• SCAV‐3 affects apoptotic cell degradation in Caenorhabditis elegans

  2023cites this paper
• Developmentally programmed histone H3 expression regulates cellular plasticity at the parental-to-early embryo transition

  2023cites this paper
• Glial Draper signaling triggers cross-neuron plasticity in bystander neurons after neuronal cell death

  2023cites this paper
• Dock7 regulates AKT and mTOR/S6K activity required for the transformed phenotypes and survival of cancer cells

  2023cites this paper
• Apoptosis and beyond: A new era for programmed cell death in Caenorhabditis elegans.

  2023cites this paper
• Life-Cycle-Dependent Toxicities of Mono- and Bifunctional Alkylating Agents in the 3R-Compliant Model Organism C. elegans

  2023cites this paper
• Caenorhabditis elegans NSE3 homolog (MAGE-1) is involved in genome stability and acts in inter-sister recombination during meiosis.

  2023cites this paper
• Actomyosin-mediated apical constriction promotes physiological germ cell death in C. elegans

  2023cites this paper
• Two predicted α-helices within the prion-like domain of TIAR-1 play a crucial role in its association with stress granules in Caenorhabditis elegans

  2023cites this paper
• Microgravity alters the expressions of DNA repair genes and their regulatory miRNAs in space-flown Caenorhabditis elegans.

  2023cites this paper
• Large vesicle extrusions from C. elegans neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell

  2023influential citation
• Dock7 regulates AKT and mTOR/S6K activity required for the transformed phenotypes and survival of cancer cells

  2023cites this paper
• ULK1-mediated phosphorylation regulates the conserved role of YKT6 in autophagy

  2023cites this paper
• Germline mitotic quiescence and cell death are induced in Caenorhabditis elegans by exposure to pathogenic Pseudomonas aeruginosa.

  2023cites this paper
• How do necrotic cells expose phosphatidylserine to attract their predators—What’s unique and what’s in common with apoptotic cells

  2023cites this paper
• Germline mitotic quiescence and programmed cell death are induced in C. elegans by exposure to pathogenic P. aeruginosa

  2023cites this paper
• Glial Draper signaling triggers cross-neuron plasticity in bystander neurons after neuronal cell death in Drosophila

  2023cites this paper
• The ESCRT machinery directs quality control over inner nuclear membrane architecture

  2022cites this paper
• trim-21 promotes proteasomal degradation of CED-1 for apoptotic cell clearance in C. elegans

  2022influential citation
• Synaptic pruning through glial synapse engulfment upon motor learning

  2022cites this paper
• Monitoring the Recruitment and Fusion of Autophagosomes to Phagosomes During the Clearance of Apoptotic Cells in the Nematode Caenorhabditis elegans.

  2022cites this paper
• Loss of MTCH-1 suppresses age-related proteostasis collapse through the inhibition of programmed cell death factors.

  2022cites this paper
• Pseudokinase HPO-11 inhibits nonsense-mediated decay to ensure genome stability in C. elegans

  2022cites this paper
• Mutant C. elegans p53 Together with Gain-of-Function GLP-1/Notch Decreases UVC-Damage-Induced Germline Cell Death but Increases PARP Inhibitor-Induced Germline Cell Death

  2022cites this paper
• The Ubiquitin-Proteasome System in Apoptosis and Apoptotic Cell Clearance

  2022cites this paper
• Wun2-mediated integrin recycling promotes apoptotic cell clearance in Drosophila melanogaster.

  2022cites this paper
• Loss of NSE-4 Perturbs Genome Stability and DNA Repair in Caenorhabditis elegans

  2022cites this paper
• Disruption of the lipolysis pathway results in stem cell death through a sterile immunity-like pathway in adult Drosophila

  2022cites this paper
• Visualizing and quantifying molecular and cellular processes in C. elegans using light microscopy.

  2022cites this paper
• Developmentally programmed epigenome regulates cellular plasticity at the parental-to-zygote transition

  2022cites this paper
• Large vesicle extrusion from C. elegans neurons requires phagocytic interaction via the ARF-6 and CED-1/DRAPER pathways

  2022cites this paper
• Repurposing the Killing Machine: Non-canonical Roles of the Cell Death Apparatus in Caenorhabditis elegans Neurons

  2022cites this paper
• Cell biology in neuroscience: Architects in neural circuit design: Cell biology in neuroscience: Architects in neural circuit design: glia control neuron numbers and connectivity glia control neuron numbers and connectivity

  2022cites this paper
• The Drosophila chemokine–like Orion bridges phosphatidylserine and Draper in phagocytosis of neurons

  2022cites this paper
• Caenorhabditis elegans NHR-14/HNF4α regulates DNA damage-induced apoptosis through cooperating with cep-1/p53

  2022cites this paper
• The C. elegans gonadal sheath Sh1 cells extend asymmetrically over a differentiating germ cell population in the proliferative zone

  2021influential citation
• Regulated Apoptosis In C. Elegans Development

  2021cites this paper
• Conserved and Distinct Elements of Phagocytosis in Human and C. elegans

  2021cites this paper
• The C. elegans gonadal sheath Sh1 cells associate selectively with a differentiating germ cell population in the proliferative zone

  2021influential citation
• Detection of Caenorhabditis elegans Germ Cell Apoptosis Following Exposure to Environmental Contaminant Mixtures: A Crude Oil-Dispersant Mixture Example.

  2021cites this paper
• Autophagosomes fuse to phagosomes and facilitate the degradation of apoptotic cells in Caenorhabditis elegans

  2021cites this paper
• Innexin function dictates the spatial relationship between distal somatic cells in the Caenorhabditis elegans gonad without impacting the germline stem cell pool

  2021influential citation
• Modular Organization of Engulfment Receptors and Proximal Signaling Networks: Avenues to Reprogram Phagocytosis

  2021cites this paper
• The basic science of optic nerve regeneration

  2021cites this paper
• Autophagy & Phagocytosis in Neurological Disorders and their Possible Cross-talk

  2021cites this paper
• Worms, Fat, and Death: Caenorhabditis elegans Lipid Metabolites Regulate Cell Death

  2021cites this paper
• An RNAi screen of the kinome in epithelial follicle cells of the Drosophila melanogaster ovary reveals genes required for proper germline death and clearance

  2021cites this paper
• Regulation of phospholipid dynamics in brain.

  2021cites this paper
• Response of G protein-coupled receptor CED-1 in germline to polystyrene nanoparticles in Caenorhabditis elegans

  2021cites this paper
• Controlling T cells spreading, mechanics and activation by micropatterning

  2021cites this paper
• The developmental and physiological roles of phagocytosis in Caenorhabditis elegans.

  2021cites this paper
• DNA repair, recombination, and damage signaling

  2021cites this paper
• Regulators and signalling in insect antimicrobial innate immunity: Functional molecules and cellular pathways.

  2021cites this paper
• Endoplasmic Reticulum Homeostasis and Stress Responses in Caenorhabditis elegans.

  2021cites this paper
• Germ cell apoptosis is critical to maintain Caenorhabditis elegans offspring viability in stressful environments

  2021cites this paper
• ERK phosphorylates chromosomal axis component HORMA domain protein HTP-1 to regulate oocyte numbers

  2020cites this paper
• Endpoints for Assessing the Toxicity on Secondary Targeted Organs

  2020cites this paper
• Oocyte aging is controlled by mitogen‐activated protein kinase signaling

  2020cites this paper
• Neonicotinoid-containing insecticide disruption of growth, locomotion, and fertility in Caenorhabditis elegans

  2020cites this paper