A role for FADD in T cell activation and development.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Immunity

• Publication date

  1998-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S1074-7613(00)80549-XPMID 9586634
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1999cited by this paper
• TNF receptor-deficient mice reveal striking differences between several models of thymocyte negative selection.

  1998cited by this paper
• Negative Selection in the Thymus Includes Semimature T Cells

  1997cited by this paper
• Fas-associated Death Domain Protein Interleukin-1β-converting Enzyme 2 (FLICE2), an ICE/Ced-3 Homologue, Is Proximally Involved in CD95- and p55-mediated Death Signaling*

  1997cited by this paper
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  1997cited by this paper
• Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice.

  1997cited by this paper
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  1997cited by this paper
• Activation of Multiple Interleukin-1β Converting Enzyme Homologues in Cytosol and Nuclei of HL-60 Cells during Etoposide-induced Apoptosis*

  1997cited by this paper
• The Receptor for the Cytotoxic Ligand TRAIL

  1997cited by this paper
• TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95).

  1997cited by this paper
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  1997cited by this paper
• The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice.

  1996cited by this paper
• CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO‐1)‐transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease.

  1996influential reference
• A mouse Fas-associated protein with homology to the human Mort1/FADD protein is essential for Fas-induced apoptosis

  1996cited by this paper
• Fas modulation of apoptosis during negative selection of thymocytes.

  1996cited by this paper
• FADD/MORT1 Is a Common Mediator of CD95 (Fas/APO-1) and Tumor Necrosis Factor Receptor-induced Apoptosis (*)

  1996cited by this paper
• Role of Lymphotoxin and the Type I TNF Receptor in the Formation of Germinal Centers

  1996cited by this paper
• Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death.

  1996cited by this paper
• Enhanced and accelerated lymphoproliferation in Fas-null mice.

  1996cited by this paper
• TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways.

  1996cited by this paper
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  1996cited by this paper
• Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor.

  1996cited by this paper
• CD95-induced apoptosis of lymphocytes in an immune privileged site induces immunological tolerance.

  1996cited by this paper
• A potential mechanism of "cross-talk" between the p55 tumor necrosis factor receptor and Fas/APO1: proteins binding to the death domains of the two receptors also bind to each other

  1996cited by this paper
• Impaired negative selection of T cells in Hodgkin's disease antigen CD30-deficient mice.

  1996cited by this paper
• FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.

  1996cited by this paper
• A death-domain-containing receptor that mediates apoptosis

  1996cited by this paper
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  1995cited by this paper
• Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo

  1995cited by this paper
• An essential role for gp39, the ligand for CD40, in thymic selection

  1995cited by this paper
• Cell expansion and growth arrest phases during the transition from precursor (CD4-8-) to immature (CD4+8+) thymocytes in normal and genetically modified mice.

  1995cited by this paper
• Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

  1995cited by this paper
• Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver

  1995cited by this paper
• A Novel Protein That Interacts with the Death Domain of Fas/APO1 Contains a Sequence Motif Related to the Death Domain (*)

  1995cited by this paper
• Involvement of an ICE-like protease in Fas-mediated apoptosis

  1995cited by this paper
• Fas- and Tumor Necrosis Factor-induced Apoptosis Is Inhibited by the Poxvirus crmA Gene Product (*)

  1995cited by this paper
• Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

  1995cited by this paper
• FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.

  1995cited by this paper
• Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis

  1995cited by this paper
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  1995cited by this paper
• Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family.

  1995cited by this paper
• The Fas death factor

  1995cited by this paper
• Cytotoxicity‐dependent APO‐1 (Fas/CD95)‐associated proteins form a death‐inducing signaling complex (DISC) with the receptor.

  1995cited by this paper
• Involvement of p21ras distinguishes positive and negative selection in thymocytes.

  1995cited by this paper
• Immune function in mice lacking the perforin gene.

  1994cited by this paper
• Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28

  1994cited by this paper
• Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

  1994cited by this paper
• Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

  1994cited by this paper
• T-cell apoptosis detected in situ during positive and negative selection in the thymus

  1994cited by this paper
• Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation.

  1994cited by this paper
• The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice.

  1994cited by this paper
• Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes.

  1994cited by this paper
• Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand.

  1994cited by this paper
• Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity.

  1994cited by this paper
• Inhibition of interleukin-1 beta converting enzyme by the cowpox virus serpin CrmA. An example of cross-class inhibition.

  1994cited by this paper
• The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster.

  1994cited by this paper
• Synthesis of a fluorogenic interleukin-1 beta converting enzyme substrate based on resonance energy transfer.

  1994cited by this paper
• The role of the Fas lytic pathway in a perforin-less CTL hybridoma.

  1994cited by this paper
• Control points in early T-cell development.

  1993cited by this paper
• A dominant‐negative transgene defines a role for p56lck in thymopoiesis.

  1993cited by this paper
• A role for a pre-T-cell receptor in T-cell development.

  1993cited by this paper
• Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity

  1993cited by this paper
• Selection of the T cell receptor repertoire in Lpr mice.

  1993cited by this paper
• Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

  1992cited by this paper
• Identification and distribution of the costimulatory receptor CD28 in the mouse.

  1992cited by this paper
• Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme.

  1992cited by this paper
• Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

  1992cited by this paper
• Viral inhibition of inflammation. Cowpox virus encodes an inhibitor of the interleukin 1β converting enzyme.

  1992cited by this paper
• Inhibition of T‐cell receptor beta‐chain gene rearrangement by overexpression of the non‐receptor protein tyrosine kinase p56lck.

  1992cited by this paper
• Genotype‐restricted lymphoproliferation in autoimmune lpr mice

  1991cited by this paper
• The majority of CD4+8- thymocytes are functionally immature.

  1991cited by this paper
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  1991cited by this paper
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  1991cited by this paper
• In vivo administration of monoclonal antibodies to the CD3 T cell receptor complex induces cell death (apoptosis) in immature thymocytes.

  1991cited by this paper
• Differences defined by bone marrow transplantation suggest that lpr and gld are mutations of genes encoding an interacting pair of molecules

  1990cited by this paper
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  1990cited by this paper
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  1990cited by this paper
• Origin and selection of peripheral CD4−CD8− T cells bearing α/β T cell antigen receptors in autoimmune gld mice

  1990cited by this paper
• Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP‐ribosyltransferase.

  1990cited by this paper
• The expanded populations of CD4-CD8- T cell receptor alpha/beta+ T cells associated with the lpr and gld mutations are CD2-.

  1990cited by this paper
• Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

  1988cited by this paper
• Deletion of potentially self-reactive T cell receptor specificities in L3T4-, Lyt-2- T cells of lpr mice [published erratum appears in J Exp Med 1989 Apr 1;169(4):1515-6]

  1988cited by this paper

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  2024cites this paper
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  2023cites this paper
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  2019cites this paper
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  2018cites this paper
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