Complementing the randomized controlled trial evidence base. Evolution not revolution.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Annals of the American Thoracic Society

• Publication date

  2014-02-21

• Fields of study

  Medicine

• Identifiers
  DOI 10.1513/AnnalsATS.201308-276RMPMID 24559027
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Quality standards for real-world research. Focus on observational database studies of comparative effectiveness.

  2014cited by this paper
• Effect of Inhaled Corticosteroid Therapy Step-Down and Dosing Regimen on Measures of Asthma Control

  2013cited by this paper
• Effect of montelukast for treatment of asthma in cigarette smokers.

  2013cited by this paper
• Efficacy versus effectiveness trials: informing guidelines for asthma management

  2013cited by this paper
• Integrating real-life studies in the global therapeutic research framework.

  2013cited by this paper
• The at-risk registers in severe asthma (ARRISA) study: a cluster-randomised controlled trial examining effectiveness and costs in primary care

  2012cited by this paper
• Device type and real-world effectiveness of asthma combination therapy: an observational study.

  2011cited by this paper
• Pragmatic trials: how to adjust for the ‘Hawthorne effect’?

  2011cited by this paper
• Asthma treatment guidelines meet the real world.

  2011cited by this paper
• Leukotriene antagonists as first-line or add-on asthma-controller therapy.

  2011cited by this paper
• Clinical trials and tribulations: the MASCOT study

  2011cited by this paper
• Inhaler devices for asthma: a call for action in a neglected field

  2011cited by this paper
• UNLOCK: Uncovering and Noting Long-term Outcomes in COPD to enhance knowledge.

  2010cited by this paper
• The value of self-report assessment of adherence, rhinitis and smoking in relation to asthma control.

  2009cited by this paper
• Comparative-effectiveness research--implications of the Federal Coordinating Council's report.

  2009cited by this paper
• Global strategy for asthma management and prevention: GINA executive summary

  2008cited by this paper
• Impact of comorbidities on asthma

  2008cited by this paper
• External validity of randomized controlled trials in COPD.

  2007cited by this paper
• Higher BMI is associated with worse asthma control and quality of life but not asthma severity.

  2006cited by this paper
• Evidence-Based Guidelines : Device Selection and Outcomes of Aerosol

  2005cited by this paper
• How representative are clinical study patients with asthma or COPD for a larger "real life" population of patients with obstructive lung disease?

  2005cited by this paper
• Are overweight asthmatics more difficult to control?

  2005cited by this paper
• Efficacy of low and high dose inhaled corticosteroid in smokers versus non-smokers with mild asthma

  2005cited by this paper
• Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase.

  2004cited by this paper
• Cigarette smoking impairs the therapeutic response to oral corticosteroids in chronic asthma.

  2003cited by this paper
• Does smoking affect the outcome of patient education and self-management in asthmatics?

  2003cited by this paper
• Assessment of Handling of Inhaler Devices in Real Life: An Observational Study in 3811 Patients in Primary Care

  2003cited by this paper
• Misuse of corticosteroid metered-dose inhaler is associated with decreased asthma stability

  2002cited by this paper
• Influence of cigarette smoking on inhaled corticosteroid treatment in mild asthma

  2002cited by this paper
• Comparison of the effectiveness of inhaler devices in asthma and chronic obstructive airways disease: a systematic review of the literature.

  2001cited by this paper
• Effects of weight loss on peak flow variability, airways obstruction, and lung volumes in obese patients with asthma.

  2000cited by this paper
• Cigarette smoking and asthma symptom severity among adult asthmatics.

  1999cited by this paper
• Journal of Asthma and Allergy Dovepress Effectiveness of Inhaler Types for Real-world Asthma Management: Retrospective Observational Study Using the Gprd

  year unknowncited by this paper

• Baseline Characteristics and Self‐Reported Use of Chronic Daily Therapies of the Home Reported Outcomes With CFTR Modulator Therapy (HERO‐2) Cohort

  2025cites this paper
• Real-World Evidence Acceptability and Use in Breast Cancer Treatment Decision-Making in the United States: Call-to-Action from a Multidisciplinary Think Tank

  2025cites this paper
• A Review of Remote Monitoring in Neuromodulation for Chronic Pain Management

  2024cites this paper
• Is asthma remission an important clinical outcome in asthma management?

  2024cites this paper
• Comparing Conventional Medical Management to Spinal Cord Stimulation for the Treatment of Low Back Pain in a Cohort of DISTINCT RCT Patients

  2024cites this paper
• Remote Management of Spinal Cord Stimulation Devices for Chronic Pain: Expert Recommendations on Best Practices for Proper Utilization and Future Considerations.

  2023cites this paper
• Evaluation of Risk Scores to Predict Pediatric Severe Asthma Exacerbations.

  2021cites this paper
• Long-Term Safety and Effectiveness of Thyrotropin Alfa in Japanese Patients: A Post-Marketing Surveillance Study

  2021cites this paper
• Versorgungsforschung mit pflanzlichen Arzneimitteln – Die pharmako-epidemiologische Datenbank PhytoVIS

  2021cites this paper
• Adalimumab and infliximab survival in patients with hidradenitis suppurativa: a daily practice cohort study

  2021cites this paper
• Long-term safety and effectiveness of denosumab in Japanese patients with osteoporosis: 3-year post-marketing surveillance study

  2021cites this paper
• Efficacy and Safety of 10 kHz Spinal Cord Stimulation for the Treatment of Chronic Pain: A Systematic Review and Narrative Synthesis of Real-World Retrospective Studies

  2021cites this paper
• A Pharmacy-Based eHealth Intervention Promoting Correct Use of Medication in Patients With Asthma and COPD: Nonrandomized Pre-Post Study

  2021cites this paper
• Expanding restrictive transfusion evidence in surgical practice: a multicentre, prospective cohort study.

  2021cites this paper
• Les effets d’une intervention musicale en soins palliatifs : intérêt d’un protocole à cas unique à baseline multiples

  2021cites this paper
• Effectiveness of benralizumab in severe eosinophilic asthma: Distinct sub‐phenotypes of response identified by cluster analysis

  2021cites this paper
• Clinical and economic utility of a preterm birth predictor derived from an analysis of a large and diverse pregnancy cohort

  2021cites this paper
• Retrospective Analysis of Real-World Outcomes of 10 kHz SCS in Patients with Upper Limb and Neck Pain

  2020cites this paper
• Observational studies assessing the pharmacological treatment of obstructive lung disease: strengths, challenges and considerations for study design

  2020cites this paper
• Introduction: Real-World Evidence in Type 2 Diabetes

  2020cites this paper
• Pharmaco-epidemiological research on herbal medicinal products in the paediatric population: data from the PhytoVIS study

  2019cites this paper
• Prospective observational study in patients with obstructive lung disease: NOVELTY design

  2019cites this paper
• Comparison of adverse events associated with different spacers used with non-extrafine beclometasone dipropionate for asthma

  2019cites this paper
• The Case for Real-world Evidence in the Future of Clinical Research on Chronic Myeloid Leukemia.

  2019cites this paper
• TREatment of ATopic eczema (TREAT) Registry Taskforce: consensus on how and when to measure the core dataset for atopic eczema treatment research registries

  2019cites this paper
• A multicenter real‐world review of 10 kHz SCS outcomes for treatment of chronic trunk and/or limb pain

  2019cites this paper
• Quality standards in respiratory real-life effectiveness research: the REal Life EVidence AssessmeNt Tool (RELEVANT): report from the Respiratory Effectiveness Group—European Academy of Allergy and Clinical Immunology Task Force

  2019cites this paper
• 2019 ARIA Care pathways for allergen immunotherapy

  2019cites this paper
• Comparing a fixed combination of budesonide/formoterol with other inhaled corticosteroid plus long-acting beta-agonist combinations in patients with chronic obstructive pulmonary disease: a review

  2019cites this paper
• A systematic review of complementary and alternative medicine in oncology: Psychological and physical effects of manipulative and body-based practices

  2019cites this paper
• Real-world efficacy and safety of nebivolol in Korean patients with hypertension from the BENEFIT KOREA study.

  2019cites this paper
• Screening for Bronchoscopic Lung Volume Reduction: Reasons for Not Receiving Interventional Treatment

  2019cites this paper
• Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 2).

  2019cites this paper
• PEER-REVIEWED JOURNAL EDITORS’ VIEWS ON REAL-WORLD EVIDENCE

  2018cites this paper
• Evaluating the design and reporting of pragmatic trials in osteoarthritis research

  2018cites this paper
• Initial Results of Secukinumab Drug Survival in Patients with Psoriasis: A Multicentre Daily Practice Cohort Study.

  2018cites this paper
• Effectiveness of an annular closure device in a “real-world” population: stratification of registry data using screening criteria from a randomized controlled trial

  2018cites this paper
• Performance of database-derived severe exacerbations and asthma control measures in asthma: responsiveness and predictive utility in a UK primary care database with linked questionnaire data

  2018cites this paper
• Matched cohort study of therapeutic strategies to prevent preschool wheezing/asthma attacks

  2018cites this paper
• An evaluation of exact matching and propensity score methods as applied in a comparative effectiveness study of inhaled corticosteroids in asthma

  2017cites this paper
• Evidence-based decision-making for primary care: The interpretation and role of pragmatic trials.

  2017cites this paper
• Real-Life Outcomes for Patients with Asthma Prescribed Spacers for Use with Either Extrafine- or Fine-Particle Inhaled Corticosteroids.

  2017cites this paper
• The use of multiple respiratory inhalers requiring different inhalation techniques has an adverse effect on COPD outcomes

  2016cites this paper
• Effectiveness of allergic rhinitis treatments in real-life with a focus on MP-AzeFlu

  2016cites this paper
• Has dementia research lost its sense of reality? A descriptive analysis of eligibility criteria of Dutch dementia research protocols.

  2016cites this paper
• Type-2 diabetes primary prevention program implemented in routine primary care: a process evaluation study

  2016cites this paper
• Asthma-Related Outcomes in Patients Initiating Extrafine Ciclesonide or Fine-Particle Inhaled Corticosteroids

  2016cites this paper
• Asthma management in primary care: caring, sharing and working together

  2016cites this paper
• Asthma phenotypes: the intriguing selective intervention with Montelukast

  2016cites this paper
• Cost-Effectiveness of Asthma Step-Up Therapy as an Increased Dose of Extrafine-Particle Inhaled Corticosteroid or Add-On Long-Acting Beta2-Agonist

  2016cites this paper
• One-Legged Cycle Training for Chronic Obstructive Pulmonary Disease. A Pragmatic Study of Implementation to Pulmonary Rehabilitation.

  2015cites this paper
• Current controversies and challenges in allergic rhinitis

  2015cites this paper
• Are Asthmatics Enrolled in Randomized Trials Representative of Real-Life Outpatients?

  2015cites this paper
• Small-particle Inhaled Corticosteroid as First-line or Step-up Controller Therapy in Childhood Asthma.

  2015cites this paper
• Current controversies and challenges in allergic rhinitis management

  2015influential citation
• Evidence-informed person-centred health care (part II): are 'cognitive biases plus' underlying the EBM paradigm responsible for undermining the quality of evidence?

  2014cites this paper
• Randomized Controlled Trial versus Real-World Study in Postherpetic Neuralgia

  2014cites this paper
• Fluticasone propionate/formoterol fumarate in fixed-dose combination for the treatment of asthma

  2014cites this paper
• Randomized Controlled Trial versus Real-World Study in Postherpetic

  2014cites this paper
• Comparing the effectiveness of small-particle versus large-particle inhaled corticosteroid in COPD

  2014cites this paper
• Comparing the effectiveness of small-particle versus large-particle inhaled corticosteroid in COPD

  2014cites this paper
• Законодательное регулирование обращения биологически активных добавок к пище в Европейском союзе и отдельных странах Европы. Часть 2

  2014cites this paper