The Importance of Size: Successful Recanalization by Intravenous Thrombolysis in Acute Anterior Stroke Depends on Thrombus Length

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Stroke

• Publication date

  2011-06-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1161/STROKEAHA.110.609693PMID 21474810
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1983cited by this paper

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