Regulators of mitochondrial complex I activity: A review of literature and evaluation in postmortem prefrontal cortex from patients with bipolar disorder.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Psychiatry Research

• Publication date

  2016-02-28

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.psychres.2015.12.015PMID 26723136
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders

  2015cited by this paper
• Agitation for recognition by DSM-5 mixed features specifier signals fatigue?

  2015cited by this paper
• Mitochondrial dysfunction in the pathophysiology of bipolar disorder: effects of pharmacotherapy.

  2015cited by this paper
• Three paths to drug discovery in psychiatry.

  2015cited by this paper
• Mitochondrial dysfunction in schizophrenia: pathways, mechanisms and implications.

  2015cited by this paper
• Imp2 regulates GBM progression by activating IGF2/PI3K/Akt pathway

  2015cited by this paper
• An updated meta-analysis of oxidative stress markers in bipolar disorder.

  2014cited by this paper
• Sex hormones and biomarkers of neuroprotection and neurodegeneration: implications for female reproductive events in bipolar disorder

  2014cited by this paper
• The Glutathione System: A New Drug Target in Neuroimmune Disorders

  2014cited by this paper
• A four week randomised control trial of adjunctive medroxyprogesterone and tamoxifen in women with mania.

  2014cited by this paper
• Altered dopamine homeostasis differentially affects mitochondrial voltage-dependent anion channels turnover.

  2014cited by this paper
• Altered plasma glutathione levels in bipolar disorder indicates higher oxidative stress; a possible risk factor for illness onset despite normal brain-derived neurotrophic factor (BDNF) levels

  2014cited by this paper
• Estradiol for treatment-resistant schizophrenia: a large-scale randomized-controlled trial in women of child-bearing age

  2014cited by this paper
• The neurobiology of bipolar disorder: identifying targets for specific agents and synergies for combination treatment.

  2014cited by this paper
• Lithium and the other mood stabilizers effective in bipolar disorder target the rat brain arachidonic acid cascade.

  2014cited by this paper
• Oxidative & nitrosative stress in depression: why so much stress?

  2014cited by this paper
• Neuropathological and neuromorphometric abnormalities in bipolar disorder: view from the medial prefrontal cortical network.

  2014cited by this paper
• The role of estrogen in bipolar disorder, a review

  2014cited by this paper
• IMP2 regulates differentiation potentials of mouse neocortical neural precursor cells

  2013cited by this paper
• Assessing the Roles of Stimulants/Stimulant-like Drugs and Dopamine-agonists in the Treatment of Bipolar Depression

  2013cited by this paper
• A fresh look at complex I in microarray data: clues to understanding disease-specific mitochondrial alterations in bipolar disorder.

  2013cited by this paper
• Reduction of STAT3 expression induces mitochondrial dysfunction and autophagy in cardiac HL-1 cells.

  2013cited by this paper
• Mitochondrial complex I.

  2013cited by this paper
• The relationship between bipolar disorder and type 2 diabetes: More than just co-morbid disorders

  2013cited by this paper
• SIRT3: A Central Regulator of Mitochondrial Adaptation in Health and Disease.

  2013cited by this paper
• SIRT3 regulation of mitochondrial oxidative stress.

  2013cited by this paper
• Reactive oxygen species and the free radical theory of aging.

  2013cited by this paper
• Coenzyme Q10 Depletion in Medical and Neuropsychiatric Disorders: Potential Repercussions and Therapeutic Implications

  2013cited by this paper
• [Function of DJ-1 in mitochondria].

  2012cited by this paper
• Differential Toxicity of 6-Hydroxydopamine in SH-SY5Y Human Neuroblastoma Cells and Rat Brain Mitochondria: Protective Role of Catalase and Superoxide Dismutase

  2012cited by this paper
• Bipolar disorder

  2012cited by this paper
• DJ-1 protects dopaminergic neurons against rotenone-induced apoptosis by enhancing ERK-dependent mitophagy.

  2012cited by this paper
• Mitochondrial metabolism, sirtuins, and aging.

  2012cited by this paper
• The role of DJ-1 in anti-apoptosis

  2012cited by this paper
• Glucose Modulates Respiratory Complex I Activity in Response to Acute Mitochondrial Dysfunction

  2012cited by this paper
• Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells.

  2012cited by this paper
• The Parkinson's disease-related genes act in mitochondrial homeostasis.

  2012cited by this paper
• Differential effects of insulin on peripheral diabetes-related changes in mitochondrial bioenergetics: involvement of advanced glycosylated end products.

  2011cited by this paper
• Mitochondrial dysfunction mediated by quinone oxidation products of dopamine: Implications in dopamine cytotoxicity and pathogenesis of Parkinson's disease.

  2011cited by this paper
• DJ‐1 deficiency in astrocytes selectively enhances mitochondrial Complex I inhibitor‐induced neurotoxicity

  2011cited by this paper
• Lithium protects against oxidative stress‐mediated cell death in α‐synuclein‐overexpressing in vitro and in vivo models of Parkinson's disease

  2011cited by this paper
• Nitric oxide and DOPAC-induced cell death: from GSH depletion to mitochondrial energy crisis.

  2011cited by this paper
• Morphometric post-mortem studies in bipolar disorder: possible association with oxidative stress and apoptosis.

  2011cited by this paper
• Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia

  2011cited by this paper
• Nitrosylation and nitration of mitochondrial complex I in Parkinson's disease

  2011cited by this paper
• DJ-1 mediates paraquat-induced dopaminergic neuronal cell death.

  2011cited by this paper
• PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

  2010cited by this paper
• Stoichiometry of STAT3 and Mitochondrial Proteins

  2010cited by this paper
• Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

  2010cited by this paper
• Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder.

  2010cited by this paper
• Nitration of the mitochondrial complex I subunit NDUFB8 elicits RIP1- and RIP3-mediated necrosis.

  2010cited by this paper
• The Transgenic Overexpression of α-Synuclein and Not Its Related Pathology Associates with Complex I Inhibition*

  2010cited by this paper
• Piloting the effective therapeutic dose of adjunctive selective estrogen receptor modulator treatment in postmenopausal women with schizophrenia.

  2010cited by this paper
• Function of Mitochondrial Stat3 in Cellular Respiration

  2009cited by this paper
• alpha-Synuclein is differentially expressed in mitochondria from different rat brain regions and dose-dependently down-regulates complex I activity.

  2009cited by this paper
• Mitochondrial STAT3 Supports Ras-Dependent Oncogenic Transformation

  2009cited by this paper
• A Disruption in Iron-Sulfur Center Biogenesis via Inhibition of Mitochondrial Dithiol Glutaredoxin 2 May Contribute to Mitochondrial and Cellular Iron Dysregulation in Mammalian Glutathione-Depleted Dopaminergic Cells: Implications for Parkinson's Disease

  2009cited by this paper
• Analysis of targeted mutation in DJ-1 on cellular function in primary astrocytes.

  2009cited by this paper
• Post-transcriptional regulation of mRNA associated with DJ-1 in sporadic Parkinson disease.

  2009cited by this paper
• Glutathione—a review on its role and significance in Parkinson's disease

  2009cited by this paper
• DJ-1 binds to mitochondrial complex I and maintains its activity.

  2009cited by this paper
• DJ-1 knock-down in astrocytes impairs astrocyte-mediated neuroprotection against rotenone.

  2009cited by this paper
• Mitochondrial Glutathione, a Key Survival Antioxidant

  2009cited by this paper
• Putative psychosis genes in the prefrontal cortex: combined analysis of gene expression microarrays

  2008cited by this paper
• A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

  2008cited by this paper
• Striatal Neuroinflammation Promotes Parkinsonism in Rats

  2008cited by this paper
• Dopamine but not 3,4-dihydroxy phenylacetic acid (DOPAC) inhibits brain respiratory chain activity by autoxidation and mitochondria catalyzed oxidation to quinone products: implications in Parkinson's disease.

  2007cited by this paper
• Constitutive expression and functional characterization of mitochondrial glutaredoxin (Grx2) in mouse and human brain.

  2007cited by this paper
• Inducible Alterations of Glutathione Levels in Adult Dopaminergic Midbrain Neurons Result in Nigrostriatal Degeneration

  2007cited by this paper
• Dopamine dysregulation syndrome: implications for a dopamine hypothesis of bipolar disorder

  2007cited by this paper
• Decreased level of mitochondrial RNA by glutamate in cultured cortical neurons

  2007cited by this paper
• S-nitrosothiol inhibition of mitochondrial complex I causes a reversible increase in mitochondrial hydrogen peroxide production.

  2006cited by this paper
• Tamoxifen and Estradiol Interact with the Flavin Mononucleotide Site of Complex I Leading to Mitochondrial Failure*

  2006cited by this paper
• PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model.

  2006cited by this paper
• Up-regulation of γ-glutamyl transpeptidase activity following glutathione depletion has a compensatory rather than an inhibitory effect on mitochondrial complex I activity: Implications for Parkinson’s disease

  2006cited by this paper
• Reversible inhibition of mitochondrial complex I activity following chronic dopaminergic glutathione depletion in vitro: implications for Parkinson's disease.

  2006cited by this paper
• Up-regulation of gamma-glutamyl transpeptidase activity following glutathione depletion has a compensatory rather than an inhibitory effect on mitochondrial complex I activity: implications for Parkinson's disease.

  2006cited by this paper
• Glutathione Depletion in a Midbrain-Derived Immortalized Dopaminergic Cell Line Results in Limited Tyrosine Nitration of Mitochondrial Complex I Subunits: Implications for Parkinson's Disease

  2005cited by this paper
• Inhibition of rat brain mitochondrial electron transport chain activity by dopamine oxidation products during extended in vitro incubation: implications for Parkinson's disease.

  2005cited by this paper
• Glutathione depletion resulting in selective mitochondrial complex I inhibition in dopaminergic cells is via an NO‐mediated pathway not involving peroxynitrite: implications for Parkinson's disease

  2005cited by this paper
• Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

  2005cited by this paper
• Does alpha-synuclein modulate dopaminergic synaptic content and tone at the synapse?

  2004cited by this paper
• Does α‐synuclein modulate dopaminergic synaptic content and tone at the synapse?

  2004cited by this paper
• Glutaredoxin 2 Catalyzes the Reversible Oxidation and Glutathionylation of Mitochondrial Membrane Thiol Proteins

  2004cited by this paper
• The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease.

  2004cited by this paper
• Inhibition of mitochondrial respiratory complex I by nitric oxide, peroxynitrite and S-nitrosothiols.

  2004cited by this paper
• DJ‐1 has a role in antioxidative stress to prevent cell death

  2004cited by this paper
• Dopamine toxicity involves mitochondrial complex I inhibition: implications to dopamine-related neuropsychiatric disorders.

  2004cited by this paper
• Oxidative Damage to Mitochondrial Complex I Due to Peroxynitrite

  2003cited by this paper
• Reversible Glutathionylation of Complex I Increases Mitochondrial Superoxide Formation*

  2003cited by this paper
• Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance

  2003cited by this paper
• Chronic exposure to nitric oxide alters the free iron pool in endothelial cells: Role of mitochondrial respiratory complexes and heat shock proteins

  2003cited by this paper
• Impairment of brain mitochondrial function by reactive nitrogen species: the role of glutathione in dictating susceptibility.

  2002cited by this paper
• Oxidatively modified proteins in aging and disease.

  2002cited by this paper
• Selective nitration of mitochondrial complex I by peroxynitrite: involvement in mitochondria dysfunction and cell death of dopaminergic SH-SY5Y cells

  2002cited by this paper
• Redox analysis of human plasma allows separation of pro-oxidant events of aging from decline in antioxidant defenses.

  2002cited by this paper
• Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder?

  2002cited by this paper
• What does Stat3 do?

  2002cited by this paper
• Chronic valproate treatment decreases the in vivo turnover of arachidonic acid in brain phospholipids: a possible common effect of mood stabilizers

  2001cited by this paper
• Melatonin protects against 6‐OHDA‐induced neurotoxicity in rats: a role for mitochondrial complex I activity

  2001cited by this paper

• Roles of SIRT3 in aging and aging-related diseases

  2025cites this paper
• Downregulated mitochondria-encoded long non-coding RNAs in mood disorders.

  2025cites this paper
• Neuronal Synaptic Communication and Mitochondrial Energetics in Human Health and Disease.

  2025cites this paper
• Are the epigenetic changes predictive of therapeutic efficacy for psychiatric disorders? A translational approach towards novel drug targets.

  2022cites this paper
• The Role of Mitonuclear Incompatibility in Bipolar Disorder Susceptibility and Resilience Against Environmental Stressors

  2021cites this paper
• Diagnosis- and Cell Type-Specific Mitochondrial Functional Pathway Signatures in Schizophrenia and Bipolar Disorder.

  2020cites this paper
• Decreased mitochondrial electron transport proteins and increased complement mediators in plasma neural-derived exosomes of early psychosis

  2020cites this paper
• Genetic Advance in Depressive Disorder.

  2019cites this paper
• Experimental enhancement of cellular OXPHOS reliance for mitochondrial health assessments - Development and characterization of a rapid and efficient method to induce OXPHOS in skin fibroblasts, for the assessment of mitochondiral toxicity and protection.

  2019cites this paper
• Recent Advancements in Bipolar Disorder studies through Genomic, Epigenomic and Metagenomic Approaches

  2019cites this paper
• Mechanisms Underpinning the Polypharmacy Effects of Medications in Psychiatry

  2018cites this paper
• Mitochondrial Complex I Deficiency in Schizophrenia and Bipolar Disorder and Medication Influence

  2017cites this paper
• Dissecting bipolar disorder complexity through epigenomic approach

  2016cites this paper