Telomere length and proliferation potential of hematopoietic stem cells.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Journal of Cell Science

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 7738087
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Telomerase activity in human ovarian carcinoma.

  1994influential reference
• The yeast telomere‐binding protein RAP1 binds to and promotes the formation of DNA quadruplexes in telomeric DNA.

  1994cited by this paper
• Telomeres: no end in sight.

  1994cited by this paper
• Activation of telomerase in a human tumor.

  1994cited by this paper
• Activation of telomerase in a human tumor.

  1994cited by this paper
• Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells.

  1994cited by this paper
• Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

  1994cited by this paper
• Ontogeny-related changes in proliferative potential of human hematopoietic cells

  1993cited by this paper
• SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres.

  1993cited by this paper
• Hematopoietic regulators: redundancy or subtlety?

  1993cited by this paper
• Lineage commitment in human hemopoiesis involves asymmetric cell division of multipotent progenitors and does not appear to be influenced by cytokines

  1993cited by this paper
• Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes.

  1993influential reference
• Loss of a yeast telomere: arrest, recovery, and chromosome loss.

  1993influential reference
• Growth of human umbilical-cord blood in longterm haemopoietic cultures.

  1992cited by this paper
• The telomere hypothesis of cellular aging.

  1992cited by this paper
• Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

  1992influential reference
• Telomere length predicts replicative capacity of human fibroblasts.

  1992cited by this paper
• Does stem cell exhaustion result from combining hematopoietic growth factors with chemotherapy? If so, how do we prevent it?

  1992cited by this paper
• Significant telomere shortening in childhood leukemia.

  1992cited by this paper
• Growth characteristics and expansion of human umbilical cord blood and estimation of its potential for transplantation in adults.

  1992cited by this paper
• Telomere end-replication problem and cell aging.

  1992cited by this paper
• In vivo loss of telomeric repeats with age in humans.

  1991cited by this paper
• Structure and function of telomeres

  1991cited by this paper
• Telomere loss: mitotic clock or genetic time bomb?

  1991influential reference
• Telomere reduction in human colorectal carcinoma and with ageing

  1990cited by this paper
• Telomeres shorten during ageing of human fibroblasts

  1990cited by this paper
• Structure and function of telomeres.

  1989cited by this paper
• The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells

  1989cited by this paper
• Hemopoietic stem cells: stochastic differentiation and humoral control of proliferation.

  1989cited by this paper
• A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.

  1988cited by this paper
• Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.

  1985cited by this paper
• The hemopoietic colony stimulating factors

  1984cited by this paper
• Proliferative capacity of murine hematopoietic stem cells in vitro.

  1982cited by this paper
• Hemopoietic colony-forming cells in umbilical cord blood with extensive capability to generate mono- and multipotential hemopoietic progenitors.

  1982cited by this paper
• ORGANIZATION OF HAEMOPOIETIC STEM CELLS: THE GENERATION‐AGE HYPOTHESIS

  1979cited by this paper
• Decline in the growth potential of spleen-colonizing bone marrow stem cells of long-lived aging mice

  1976cited by this paper
• A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon.

  1973cited by this paper
• Sugar and Disease

  1972cited by this paper
• Origin of concatemeric T7 DNA.

  1972cited by this paper
• Origin of Concatemeric T7DNA

  1972cited by this paper
• [Principle of marginotomy in template synthesis of polynucleotides].

  1971cited by this paper
• Principle of marginotomy in template synthesis of polynucleotides

  1971cited by this paper
• A STOCHASTIC MODEL OF STEM CELL PROLIFERATION, BASED ON THE GROWTH OF SPLEEN COLONY-FORMING CELLS.

  1964cited by this paper

• Changing landscape of hematopoietic and mesenchymal cells and their interactions during aging and in age-related skeletal pathologies.

  2025cites this paper
• Evaluation of Erythroid Maturation Patterns in Unexplained anemia in the Elderly

  2024cites this paper
• Proteomics reveals dynamic metabolic changes in human hematopoietic stem progenitor cells from fetal to adulthood

  2024cites this paper
• Telomere length is an epigenetic trait – Implications for the use of telomerase-deficient organisms to model human disease

  2024cites this paper
• Biomarkers for aging of blood - how transferable are they between mice and humans?

  2024cites this paper
• Telomere length is not a useful tool for chronological age estimation in animals

  2023cites this paper
• Artificial size selection experiment reveals telomere length dynamics and fitness consequences in a wild passerine

  2021cites this paper
• Effects on Glial Cell Glycolysis in Schizophrenia: An Advanced Aging Phenotype?

  2019cites this paper
• Telomeres, Telomerase and Ageing.

  2018cites this paper
• Short Telomere Length as a Biomarker Risk of Lung Cancer Development Induced by High Radon Levels: A Pilot Study

  2018cites this paper
• The power of fat and its adipose‐derived stromal cells: emerging concepts for fibrotic scar treatment

  2017cites this paper
• Telomere length change plateaus at 4 years of age in Latino children: associations with baseline length and maternal change

  2016cites this paper
• The effects of proliferation and DNA damage on hematopoietic stem cell function determine aging

  2016cites this paper
• Telomere Length in Aged Mayak PA Nuclear Workers Chronically Exposed to Internal Alpha and External Gamma Radiation

  2016cites this paper
• Stem Cell versus Cancer and Cancer Stem Cell: Intricate Balance Decides Their Respective Usefulness or Harmfulness in the Biological System

  2014cites this paper
• The MNS16A polymorphism in the TERT gene in peri-centenarians from the Han Chinese population

  2014cites this paper
• Inhibition of DNA topoisomerase I activity and induction of apoptosis by thiazacridine derivatives.

  2013cites this paper
• Telomerase: from Aging to Human Cancers

  2013cites this paper
• Extracting Extra-Telomeric Phenotypes from Telomerase Mouse Models

  2013cites this paper
• Networks Establishing Hematopoietic Stem Cell Multipotency and Self-Renewal

  2012cites this paper
• Germ Cell Development, Division, Disruption and Death

  2012cites this paper
• Bone marrow and peripheral white blood cells number is affected by sleep deprivation in a murine experimental model

  2012cites this paper
• Blood telomere length in infants and their HIV-infected mothers exposed to antiretroviral therapy during pregnancy

  2011cites this paper
• Anaemia in older persons.

  2011cites this paper
• Telomere length and anaemia in old age: results from the Newcastle 85-plus Study and the Leiden 85-plus Study.

  2011cites this paper
• Telomere biology in hematopoiesis and stem cell transplantation.

  2011cites this paper
• The aging effect of chemotherapy on cultured human mesenchymal stem cells.

  2011cites this paper
• Derivation and characterization of human embryonic stem cell lines from the Chinese population.

  2011cites this paper
• Biological Differences Between Neonatal and Adult Human Hematopoietic Stem/Progenitor Cells

  2010cites this paper
• Qualitative and quantitative analysis of rabbit's fat mesenchymal stem cells.

  2010cites this paper
• The role of telomeres and telomerase complex in haematological neoplasia: the length of telomeres as a marker of carcinogenesis and prognosis of disease.

  2010cites this paper
• Flow cytometric detection of human telomerase reverse transcriptase (hTERT) expression in a subpopulation of bone marrow cells.

  2010influential citation
• Leukocyte telomere dynamics and human hematopoietic stem cell kinetics during somatic growth.

  2009influential citation
• Characterisation and developmental potential of ovine bone marrow derived mesenchymal stem cells

  2009cites this paper
• Differences amid bone marrow and cord blood hematopoietic stem/progenitor cell division kinetics

  2009cites this paper
• Activated Spinal Cord Ependymal Stem Cells Rescue Neurological Function

  2009cites this paper
• Telomere length dynamics differ in foetal and early post-natal human leukocytes in a longitudinal study

  2009cites this paper
• Telomerase in hematopoietic stem cells

  2008cites this paper
• Senescence Signatures of Human Hematopoietic Stem Cells

  2008cites this paper
• Implication des mécanismes de la réparation de l'ADN dans la maintenance des télomères et l'instabilité chromosomique dans les cellules humaines

  2008cites this paper
• Stem Cells and Cardiac Aging

  2007cites this paper
• Stem cell ageing: does it happen and can we intervene?

  2007cites this paper
• Telomeres, senescence, and hematopoietic stem cells

  2007cites this paper
• Long-term lymphoma survivors following high-dose chemotherapy and autograft: evidence of permanent telomere shortening in myeloid cells, associated with marked reduction of bone marrow hematopoietic stem cell reservoir.

  2007cites this paper
• The Telomere–Telomerase Axis and the Heart

  2006cites this paper
• Telomere length changes after umbilical cord blood transplant

  2006cites this paper
• Telomere attrition as ageing biomarker.

  2005cites this paper
• Role of Telomerase in Hematopoietic Stem Cells

  2005cites this paper
• Telomere dynamics in hematopoietic stem cells.

  2005cites this paper
• The importance of the telomere and telomerase system in hematological malignancies

  2005cites this paper
• Measurable immune dysfunction and telomere attrition in long-term allogeneic transplant recipients

  2004cites this paper
• Mathematical modeling of vascular endothelial layer maintenance: the role of endothelial cell division, progenitor cell homing, and telomere shortening.

  2004cites this paper
• Telomere biology of human hematopoietic stem cells.

  2004cites this paper
• Telomere Length and Telomerase Activity: Variations With Advancing Age and Potential Role in Childhood Malignancies

  2004cites this paper
• Estimating human hematopoietic stem cell kinetics using granulocyte telomere lengths.

  2004cites this paper
• Aging of the Hematopoietic System

  2003cites this paper
• Granulocyte colony‐stimulating factor administration upregulates telomerase activity in CD34+ haematopoietic cells and may prevent telomere attrition after chemotherapy

  2003cites this paper
• A glance into somatic stem cell biology: basic principles, new concepts, and clinical relevance.

  2003cites this paper
• Abnormal telomere metabolism in Fanconi's anaemia correlates with genomic instability and the probability of developing severe aplastic anaemia

  2003cites this paper
• Therapy‐related myelodysplasia and/or acute myeloid leukaemia after autologous haematopoietic progenitor cell transplantation in a prospective single centre cohort of 221 patients

  2003cites this paper
• Which Stem Cells Should be Used for Transplantation?

  2003cites this paper
• Telomerbiologische Untersuchungen zum zellulären Umsatz hämatopoetischer Stammzellen nach haploidenter Transplantation mit hoher Dosis an Stammzellen

  2003cites this paper
• A woman's right to choose – counselling!

  2002cites this paper
• Endometrial angiogenesis: Physiology and clinical implications

  2002cites this paper
• Spontaneous miscarriages as source of fetal stem cells.

  2002cites this paper
• Prenatal T-cell reconstitution after in utero transplantation with fetal liver cells in a patient with X-linked severe combined immunodeficiency.

  2002cites this paper
• In utero stem cell transplantation: two steps forward but one step back?

  2001cites this paper
• ARP, A Peptide Derived from the Stress-Associated Acetylcholinesterase Variant, Has Hematopoietic Growth Promoting Activities

  2001cites this paper
• Genesis of clone size heterogeneity in megakaryocytic and other hemopoietic colonies: the stochastic model revisited.

  2001cites this paper
• Granulocyte colony‐stimulating factor‐mobilized peripheral blood CD34+ cells from children contain the same levels of long‐term culture‐initiating cells producing the same numbers of colony‐forming cells as those from adults, but display greater in vitro monocyte/macrophage potential

  2001cites this paper
• Does telomere shortening count?

  2001cites this paper
• A novel model system for the study of anti-tumour T-cell memory

  2001cites this paper
• In utero stem cell transplantation in humans.

  2001cites this paper
• Age-related telomere shortening occurs in lens epithelium from old rats and is slowed by caloric restriction.

  2001cites this paper
• Biogerontological research in Canada.

  2000cites this paper
• Shortening of telomeres in recipients of both autologous and allogeneic hematopoietic stem cell transplantation

  2000cites this paper
• Interleukin 6 receptor expression by human cord blood‐ or peripheral blood‐derived primitive haematopoietic progenitors implies acquisition of different functional properties

  2000influential citation
• Prognostic implications of differences in telomere length between normal and malignant cells from patients with chronic myeloid leukemia measured by flow cytometry.

  2000cites this paper
• Detection of telomerase activity and correlation with mitotic and apoptotic indices, Ki‐67 and expression of cyclins D1 and A in cutaneous melanoma

  2000cites this paper
• Ins and Outs of Hematopoietic Stem Cells: Regulation by Genes and Stromal Cells

  2000cites this paper
• CHAPTER 43 – LYMPHOID CELLS

  2000cites this paper
• Human Telomere Length in Breast Cancer Patients before and after Chemotherapy with or without Stem Cell Transplantation

  2000cites this paper
• Why do in utero stem cell transplants sometimes fail?

  1999cites this paper
• Telomere Fluorescence Measurements in Granulocytes and T Lymphocyte Subsets Point to a High Turnover of Hematopoietic Stem Cells and Memory T Cells in Early Childhood

  1999cites this paper
• DNA replication and cancer.

  1999cites this paper
• Bioreactors for hematopoietic cell culture.

  1999cites this paper
• Development and aging of primitive hematopoietic stem cells in BALB/cBy mice.

  1999cites this paper
• Editorial: Biological Aging Research in Canada: Past, Present and Future

  1999cites this paper
• Mutations in beta-myosin S2 that cause familial hypertrophic cardiomyopathy (FHC) abolish the interaction with the regulatory domain of myosin-binding protein-C.

  1999cites this paper
• Éditorial: Recherche sur le vieillissement biologique au Canada: passé, présent et avenir

  1999cites this paper
• Progressive Telomere Shortening in Aplastic Anemia

  1998cites this paper
• Self-Renewal of Stem Cells

  1998cites this paper
• FISH goes with the flow

  1998cites this paper
• Human cord blood-derived primitive progenitors are enriched in CD34+c-kit− cells: correlation between long-term culture-initiating cells and telomerase expression

  1998cites this paper
• Cell Senescence and Aging

  1998cites this paper
• Regulation of telomerase activity in normal and malignant human cells.

  1998cites this paper
• The biology and ethics of banking fetal liver hematopoietic stem cells for in utero transplantation.

  1998cites this paper
• Age related decrease of NOR activity in bone marrow metaphase chromosomes from healthy individuals.

  1998cites this paper
• The prospects for in utero stem cell transplantation.

  1998cites this paper
• Progressive telomere shortening in aplastic anemia.

  1998cites this paper