The Effect of Ingested Glucose Dose on the Suppression of Endogenous Glucose Production in Humans

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Diabetes

• Publication date

  2017-07-06

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.2337/db17-0433PMID 28684634
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Accurate Measurement of Postprandial Glucose Turnover: Why Is It Difficult and How Can It Be Done (Relatively) Simply?

  2016cited by this paper
• Comparison of the physiological relevance of systemic vs. portal insulin delivery to evaluate whole body glucose flux during an insulin clamp.

  2015cited by this paper
• Changes in Glucose and Fat Metabolism in Response to the Administration of a Hepato-Preferential Insulin Analog

  2014cited by this paper
• The regulation of glucose metabolism: implications and considerations for the assessment of glucose homeostasis in rodents.

  2014cited by this paper
• Regulation of hepatic glucose uptake and storage in vivo.

  2012influential reference
• Portal vein and systemic adiponectin concentrations are closely linked with hepatic glucose and lipoprotein kinetics in extremely obese subjects.

  2011cited by this paper
• Incretin-Based Therapies

  2009cited by this paper
• Regulation of hepatic glucose production and the role of gluconeogenesis in humans: is the rate of gluconeogenesis constant?

  2008cited by this paper
• Insulin Resistance and Hyperinsulinemia

  2008cited by this paper
• Effects of Nonglucose Nutrients on Insulin Secretion and Action in People With Pre-Diabetes

  2007cited by this paper
• Glucose determination by means of steady-state and time-course UV fluorescence in free or immobilized Glucose Oxidase

  2007cited by this paper
• Orchestration of Glucose Homeostasis

  2007cited by this paper
• Faculty Opinions recommendation of Effects of age and sex on postprandial glucose metabolism: differences in glucose turnover, insulin secretion, insulin action, and hepatic insulin extraction.

  2006cited by this paper
• Effects of Age and Sex on Postprandial Glucose Metabolism

  2006cited by this paper
• Insulin resistance, the insulin resistance syndrome, and cardiovascular disease.

  2005cited by this paper
• Insulin dose-response curves for stimulation of splanchnic glucose uptake and suppression of endogenous glucose production differ in nondiabetic humans and are abnormal in people with type 2 diabetes.

  2004cited by this paper
• Direct measurement of pulsatile insulin secretion from the portal vein in human subjects.

  2000cited by this paper
• Effects of insulin on glucose turnover rates in vivo: isotope dilution versus constant specific activity technique.

  1996cited by this paper
• Insulin Dose-Response Characteristics for Suppression of Glycerol Release and Conversion to Glucose in Humans

  1986cited by this paper
• Regulation of Splanchnic and Peripheral Glucose Uptake by Insulin and Hyperglycemia in Man

  1983cited by this paper
• Effect of various oral glucose doses on plasma neutral amino acid levels.

  1982cited by this paper
• Dose-response characteristics for effects of insulin on production and utilization of glucose in man.

  1981cited by this paper
• Glucose oxidation in relation to the size of the oral glucose loading dose.

  1981cited by this paper
• Insulin and glucagon concentrations in portal and peripheral veins in patients with hepatic cirrhosis

  1979cited by this paper
• Glucose metabolism in man: responses to intravenous glucose infusion.

  1979cited by this paper
• The Size of the Loading Dose as an Important Determinant of the Results of the Oral Glucose Tolerance Test: A Study in Subjects with Slightly Impaired Glucose Tolerance

  1978cited by this paper
• EFFECT OF VERY SMALL CONCENTRATIONS OF INSULIN ON FOREARM METABOLISM. PERSISTENCE OF ITS ACTION ON POTASSIUM AND FREE FATTY ACIDS WITHOUT ITS EFFECT ON GLUCOSE.

  1964cited by this paper

• Analysis and boundary control of subcutaneous insulin kinetics PDE model for type one diabetes

  2026cites this paper
• Novel deuterium metabolic imaging technique reveals distinct patterns of postprandial hepatic glucose homeostasis in individuals with type 1 diabetes and healthy control individuals: a case-control study.

  2026cites this paper
• Ketone ester ingestion increases exogenous carbohydrate storage and lowers glycemia during post-exercise recovery: a randomised crossover trial

  2025cites this paper
• McArdle disease (Glycogen Storage Disease Type V) from an exercise physiology and biochemistry perspective: Important considerations for exercise and physical activity testing and data interpretation

  2025cites this paper
• McArdle disease and carbohydrate ingestion before exercise: Timing on exercise tolerance, clinical relevance, and application to real world settings

  2025cites this paper
• Crafting Mathematical Models for Type 2 Diabetes Progression: Leveraging Longitudinal Data

  2025cites this paper
• Continuous glucose monitor overestimates glycemia, with the magnitude of bias varying by postprandial test and individual – a randomized crossover trial

  2025cites this paper
• Insulin Resistance in Type 1 Diabetes: Pathophysiological, Clinical, and Therapeutic Relevance

  2025cites this paper
• Mechanistic Insights Into Postprandial Insulin-Glucagon Interactions and Their Impact on Glucose Flux After Protein-Glucose Coingestion in Humans.

  2025cites this paper
• The Glycemic Impact of Protein Ingestion in People With Type 1 Diabetes.

  2025cites this paper
• Porphyrin-based covalent organic frameworks with synergistic active centers for enhanced peroxidase-like activity as a colorimetric biosensing platform

  2025cites this paper
• Carbohydrate Ingestion before Exercise for Individuals with McArdle Disease: Survey Evidence of Implementation and Perception in Real-World Settings

  2024cites this paper
• Effects of Obesity and Hyperglycemia on Postprandial Insulin-Mediated and Non-Insulin-Mediated Glucose Disposal.

  2024cites this paper
• Daily standing time, dietary fiber, and intake of unsaturated fatty acids are beneficially associated with hepatic insulin sensitivity in adults with metabolic syndrome

  2024cites this paper
• Efficacy of Postprandial Exercise in Mitigating Glycemic Responses in Overweight Individuals and Individuals with Obesity and Type 2 Diabetes—A Systematic Review and Meta-Analysis

  2023cites this paper
• Graded Replacement of Carbohydrate-Rich Breakfast Products with Dairy Products: Effects on Postprandial Aminoacidemia, Glycemic Control, Bone Metabolism, and Satiety.

  2023cites this paper
• The impact of a single dose of whey protein on glucose flux and metabolite profiles in normoglycemic males: insights into glucagon and insulin biology.

  2023cites this paper
• Dose–response effect of pre-exercise carbohydrates under muscle glycogen unavailability: Insights from McArdle disease

  2023cites this paper
• Chronobiology of Exercise: Evaluating the Best Time to Exercise for Greater Cardiovascular and Metabolic Benefits.

  2022cites this paper
• Effects of Diet, Lifestyle, Chrononutrition and Alternative Dietary Interventions on Postprandial Glycemia and Insulin Resistance

  2022cites this paper
• Could Dietary Modification Independent of Energy Balance Influence the Underlying Pathophysiology of Type 2 Diabetes? Implications for Type 2 Diabetes Remission

  2022cites this paper
• Metabolomics and Lipidomics Signatures of Insulin Resistance and Abdominal Fat Depots in People Living with Obesity

  2022cites this paper
• Regulation of Postabsorptive and Postprandial Glucose Metabolism by Insulin-Dependent and Insulin-Independent Mechanisms: An Integrative Approach

  2021influential citation
• Estimating endogenous glucose production during exercise using heart rate: implications for diabetes management

  2021cites this paper
• Translating glucose tolerance data from mice to humans: Insights from stable isotope labelled glucose tolerance tests

  2021cites this paper
• Exercise-nutrient interactions for improved postprandial glycemic control and insulin sensitivity.

  2021cites this paper
• Endogenous glucose production in critical illness.

  2021cites this paper
• Exercise-Induced Improvements to Whole Body Glucose Metabolism in Type 2 Diabetes: The Essential Role of the Liver

  2020cites this paper
• The integrated physiology of glucose homeostasis: regulation by extracellular and intracellular nucleotide sensors

  2020cites this paper
• A Single Bout of Premeal Resistance Exercise Improves Postprandial Glucose Metabolism in Obese Men with Prediabetes.

  2020cites this paper
• Ultra rapid lispro lowers postprandial glucose and more closely matches normal physiological glucose response compared to other rapid insulin analogues: A phase 1 randomized, crossover study

  2020cites this paper
• Spatial and temporal studies of metabolic activity: contrasting biochemical kinetics in tissues and pathways during fasted and fed states.

  2019cites this paper
• Mechanisms of hyperinsulinaemia in apparently healthy non-obese young adults: role of insulin secretion, clearance and action and associations with plasma amino acids

  2019cites this paper
• Aerobic exercise training improves hepatic and muscle insulin sensitivity, but reduces splanchnic glucose uptake in obese humans with type 2 diabetes

  2019cites this paper
• Reduced insulin action in muscle of high fat diet rats over the diurnal cycle is not associated with defective insulin signaling

  2019cites this paper
• Tissue-specific insulin sensitivity in humans - with special reference to the liver

  2019cites this paper
• Glucose Appearance Rate Rather than the Blood Glucose Concentrations Explains Differences in Postprandial Insulin Responses between Wholemeal Rye and Refined Wheat Breads—Results from A Cross‐Over Meal Study

  2019cites this paper
• Divided consumption of late-night-dinner improves glucose excursions in young healthy women: A randomized cross-over clinical trial.

  2018cites this paper
• Endogenous glucose production after sequential meals in humans: evidence for more prolonged suppression after ingestion of a second meal.

  2018cites this paper
• Measurement of postprandial glucose fluxes in response to acute and chronic endurance exercise in healthy humans.

  2018cites this paper