SnapShot: Bladder Cancer.

Bladder cancers, the majority of which are urothelial carcinoma, are the most common urinary tract cancers. There are two major disease types, muscle-invasive and non-muscle-invasive, with distinct pathogenesis pathways, molecular features, and clinical outcomes. Recent genomic and transcriptomic data have significantly improved tumor sub-classification and prognostication for both patient groups and are informing improved approaches to treatment of muscle-invasive disease. To view this SnapShot, open or download the PDF.

• Publication year

  2018

• Venue

  Cancer Cell

• Publication date

  2018-08-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.ccell.2018.07.013PMID 30107181
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• No references are available for this paper.

• IGF2BP3 promotes the muscle invasion of bladder cancer via PPARγ dysregulation.

  2026cites this paper
• Functional and Mechanistic Insights of 3-Hydroxybutyrate (3-OBA) in Bladder Cancer

  2025cites this paper
• Exploring of bladder cancer immune-related genes and potential therapeutic targets based on transcriptomic data and Mendelian randomization analysis

  2025cites this paper
• Integrated network pharmacology and RNA sequencing analysis to reveal the mechanisms of Qici Sanling decoction in the treatment of gemcitabine resistant bladder cancer.

  2025cites this paper
• Integrating Genetic Alterations and Histopathological Features for Enhanced Risk Stratification in Non-Muscle-Invasive Bladder Cancer

  2024cites this paper
• An efficient improved parrot optimizer for bladder cancer classification

  2024cites this paper
• Immunogenic cell death-related signature predicts prognosis and immunotherapy efficacy in bladder cancer

  2024cites this paper
• Deciphering the molecular heterogeneity of intermediate- and (very-)high-risk non–muscle-invasive bladder cancer using multi-layered –omics studies

  2024cites this paper
• Chromene-based compounds as drug candidates for renal and bladder cancer therapy - A systematic review.

  2024cites this paper
• Preoperative Prediction of Muscle Invasiveness in Bladder Cancer: The Role of 3D Volumetric Radiomics Using Diffusion-Weighted MRI, the VI-RADS Score, or a Combination of Both

  2024cites this paper
• Insight into Fructose-to-Sucrose Ratio as the Potential Target of Urinalysis in Bladder Cancer

  2024cites this paper
• Glucose Metabolism Reprogramming in Bladder Cancer: Hexokinase 2 (HK2) as Prognostic Biomarker and Target for Bladder Cancer Therapy

  2023cites this paper
• Glutathione dynamics is a potential predictive and therapeutic trait for neoadjuvant chemotherapy response in bladder cancer

  2023cites this paper
• Can Only the Shape Feature in Radiomics Help Machine Learning Show That Bladder Cancer Has Invaded Muscles?

  2023cites this paper
• Homeobox Gene Expression Dysregulation as Potential Diagnostic and Prognostic Biomarkers in Bladder Cancer

  2023cites this paper
• The m6A Reader YTHDF2 Promotes Bladder Cancer Progression by Suppressing RIG-I–Mediated Immune Response

  2023cites this paper
• New insight in urological cancer therapy: From epithelial-mesenchymal transition (EMT) to application of nano-biomaterials.

  2023cites this paper
• A novel cuproptosis-related lncRNA signature predicts prognosis and therapeutic response in bladder cancer

  2023cites this paper
• Association of SNPs in the PAI1 Gene with Disease Recurrence and Clinical Outcome in Bladder Cancer

  2023cites this paper
• Knockdown of ZBTB11 impedes R‐loop elimination and increases the sensitivity to cisplatin by inhibiting DDX1 transcription in bladder cancer

  2022cites this paper
• B7-H4 correlates with clinical outcome and immunotherapeutic benefit in muscle-invasive bladder cancer.

  2022cites this paper
• NXPH4 Promotes Gemcitabine Resistance in Bladder Cancer by Enhancing Reactive Oxygen Species and Glycolysis Activation through Modulating NDUFA4L2

  2022cites this paper
• Immune status for monitoring and treatment of bladder cancer

  2022cites this paper
• WISP1 and miR-29c-3p are novel prognostic biomarkers and therapeutic targets for bladder cancer

  2021cites this paper
• Latency-associated peptide identifies therapeutically resistant muscle-invasive bladder cancer with poor prognosis

  2021cites this paper
• Preclinical Models for Bladder Cancer Research.

  2021cites this paper
• Loss of polarity protein Par3, via transcription factor Snail, promotes bladder cancer metastasis

  2021cites this paper
• CircLIFR synergizes with MSH2 to attenuate chemoresistance via MutSα/ATM-p73 axis in bladder cancer

  2021influential citation
• Occupational bladder cancer: A cross section survey of previous employments, tasks and exposures matched to cancer phenotypes

  2020cites this paper
• Development and validation of a nomogram for predicting survival in patients with non-metastatic primary adenocarcinoma of the bladder

  2020cites this paper
• Bioinformatic Identification of Potential Hub Genes in Muscle-Invasive Bladder Urothelial Carcinoma

  2020cites this paper
• Prognostic value of immune cell infiltration in bladder cancer: A gene expression-based study

  2020cites this paper
• PTEN: What we know of the function and regulation of this onco-suppressor factor in bladder cancer?

  2020cites this paper
• A nomogram combining long non-coding RNA expression profiles and clinical factors predicts survival in patients with bladder cancer

  2020cites this paper
• Latest progress in molecular biology and treatment in genitourinary tumours

  2020cites this paper
• Alterations in detrusor contractility in rat model of bladder cancer

  2020cites this paper
• Traditional Classification and Novel Subtyping Systems for Bladder Cancer

  2020influential citation
• Effects of Strength vs. Plyometric Training on Change of Direction Performance in Experienced Soccer Players

  2020cites this paper
• The Interplay between Oxidative Phosphorylation and Glycolysis as a Potential Marker of Bladder Cancer Progression

  2020cites this paper
• Centrosomal Proteins in Urothelial Tumors: New Pathways in Disease Pathogenesis.

  2019cites this paper
• Stromal lymphocyte infiltration is associated with tumour invasion depth but is not prognostic in high-grade T1 bladder cancer.

  2019cites this paper
• Role of the Nuclear Receptor PPARγ in Clear Cell Renal and Bladder Urotheial Carcinoma

  2019cites this paper
• COMMENTARY Centrosomal Proteins in Urothelial Tumors New Pathways in Disease Pathogenesis

  year unknowncites this paper