Microfluidic-based vascularized microphysiological systems.

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Lab on a Chip

• Publication date

  2018-09-11

• Fields of study

  Medicine, Engineering

• Identifiers
  DOI 10.1039/c8lc00285aPMID 30110034
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Past, present and future of in vitro 3D reconstructed inflammatory skin models to study psoriasis

  2018cited by this paper
• Wet‐AMD on a Chip: Modeling Outer Blood‐Retinal Barrier In Vitro

  2018cited by this paper
• Investigation on vascular cytotoxicity and extravascular transport of cationic polymer nanoparticles using perfusable 3D microvessel model.

  2018cited by this paper
• A microengineered vascularized bleeding model that integrates the principal components of hemostasis

  2018cited by this paper
• Probing the Effect of Bioinspired Nanomaterials on Angiogenic Sprouting With a Microengineered Vascular System

  2018cited by this paper
• Microvasculature on a chip: study of the Endothelial Surface Layer and the flow structure of Red Blood Cells

  2017cited by this paper
• Liver sinusoidal endothelial cells: Physiology and role in liver diseases.

  2017cited by this paper
• Human Gut-On-A-Chip Supports Polarized Infection of Coxsackie B1 Virus In Vitro

  2017cited by this paper
• Micro-engineered perfusable 3D vasculatures for cardiovascular diseases.

  2017cited by this paper
• Integrating perfusable vascular networks with a three-dimensional tissue in a microfluidic device.

  2017cited by this paper
• A 3D neurovascular microfluidic model consisting of neurons, astrocytes and cerebral endothelial cells as a blood-brain barrier.

  2017cited by this paper
• Tumor Microenvironment on a Chip: The Progress and Future Perspective

  2017cited by this paper
• Vasculature-On-A-Chip for In Vitro Disease Models

  2017cited by this paper
• Microfluidic modeling of the biophysical microenvironment in tumor cell invasion.

  2017cited by this paper
• A Low Permeability Microfluidic Blood-Brain Barrier Platform with Direct Contact between Perfusable Vascular Network and Astrocytes

  2017cited by this paper
• Vascular heterogeneity and specialization in development and disease

  2017cited by this paper
• A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications.

  2017cited by this paper
• Multicellular Vascularized Engineered Tissues through User‐Programmable Biomaterial Photodegradation

  2017cited by this paper
• Characterization of vascular permeability using a biomimetic microfluidic blood vessel model.

  2017cited by this paper
• Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle

  2017cited by this paper
• An end-user perspective on Organ-on-a-Chip : Assays and usability aspects

  2017cited by this paper
• Advanced biomaterials and microengineering technologies to recapitulate the stepwise process of cancer metastasis.

  2017cited by this paper
• Microfabricated blood vessels undergo neoangiogenesis.

  2017cited by this paper
• Tissue chips - innovative tools for drug development and disease modeling.

  2017cited by this paper
• Effect of shear stress on iPSC-derived human brain microvascular endothelial cells (dhBMECs)

  2017cited by this paper
• Microfluidic traction force microscopy to study mechanotransduction in angiogenesis

  2017cited by this paper
• Biomimetic Model of Tumor Microenvironment on Microfluidic Platform

  2017cited by this paper
• Hybrid polymer microfluidic platform to mimic varying vascular compliance and topology.

  2017cited by this paper
• "Open-top" microfluidic device for in vitro three-dimensional capillary beds.

  2017cited by this paper
• Organ-on-a-chip devices advance to market.

  2017cited by this paper
• Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes

  2017cited by this paper
• Organotypic vasculature: From descriptive heterogeneity to functional pathophysiology

  2017cited by this paper
• Skin integrated with perfusable vascular channels on a chip.

  2017cited by this paper
• Plastic roles of pericytes in the blood–retinal barrier

  2017cited by this paper
• Corrigendum: Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle

  2017cited by this paper
• Utility of microfluidic devices to study the platelet–endothelium interface

  2017cited by this paper
• Mimicking arterial thrombosis in a 3D-printed microfluidic in vitro vascular model based on computed tomography angiography data.

  2017cited by this paper
• Advances in on-chip vascularization.

  2017cited by this paper
• Endothelial Cell Culture Under Perfusion On A Polyester-Toner Microfluidic Device

  2017cited by this paper
• Journal of Health Economics

  2016cited by this paper
• Three-dimensional biomimetic model to reconstitute sprouting lymphangiogenesis in vitro.

  2016cited by this paper
• Biomimetic tumor-induced angiogenesis and anti-angiogenic therapy in a microfluidic model

  2016cited by this paper
• 3D microtumors in vitro supported by perfused vascular networks

  2016cited by this paper
• Biodegradable scaffold with built-in vasculature for organ-on-a-chip engineering and direct surgical anastomosis

  2016cited by this paper
• Interstitial flow regulates the angiogenic response and phenotype of endothelial cells in a 3D culture model.

  2016cited by this paper
• Studying the influence of angiogenesis in in vitro cancer model systems.

  2016cited by this paper
• Organization of Endothelial Cells, Pericytes, and Astrocytes into a 3D Microfluidic in Vitro Model of the Blood-Brain Barrier.

  2016cited by this paper
• A dynamic in vivo-like organotypic blood-brain barrier model to probe metastatic brain tumors

  2016cited by this paper
• Innovation in the pharmaceutical industry: New estimates of R&D costs.

  2016cited by this paper
• Stable engineered vascular networks from human induced pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogels.

  2016cited by this paper
• Forces and mechanotransduction in 3D vascular biology.

  2016cited by this paper
• Elastomeric free-form blood vessels for interconnecting organs on chip systems.

  2016cited by this paper
• Modular, pumpless body-on-a-chip platform for the co-culture of GI tract epithelium and 3D primary liver tissue.

  2016cited by this paper
• Angiogenesis in Liquid Tumors: An In Vitro Assay for Leukemic‐Cell‐Induced Bone Marrow Angiogenesis

  2016cited by this paper
• Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip.

  2016cited by this paper
• Angiocrine functions of organ-specific endothelial cells

  2016cited by this paper
• Skin-on-a-chip model simulating inflammation, edema and drug-based treatment

  2016cited by this paper
• Elucidation of the Roles of Tumor Integrin β1 in the Extravasation Stage of the Metastasis Cascade.

  2016cited by this paper
• Fabrication of multilayered vascular tissues using microfluidic agarose hydrogel platforms

  2016cited by this paper
• Human in vitro 3D co-culture model to engineer vascularized bone-mimicking tissues combining computational tools and statistical experimental approach.

  2016cited by this paper
• In vitro micro-physiological immune-competent model of the human skin.

  2016cited by this paper
• Blood flow controls bone vascular function and osteogenesis

  2016cited by this paper
• High-throughput compound evaluation on 3D networks of neurons and glia in a microfluidic platform

  2016cited by this paper
• Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip

  2016cited by this paper
• Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling.

  2016cited by this paper
• Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels.

  2016cited by this paper
• An in vitro vascular chip using 3D printing-enabled hydrogel casting

  2016cited by this paper
• Recent advances in understanding the roles of vascular endothelial cells in allergic inflammation.

  2016cited by this paper
• Human Skin Constructs with Spatially Controlled Vasculature Using Primary and iPSC‐Derived Endothelial Cells

  2016cited by this paper
• 3D-printed fluidic networks as vasculature for engineered tissue.

  2016cited by this paper
• Immunosurveillance of the liver by intravascular effector CD8(+) T cells.

  2015cited by this paper
• Differentiation of neuroepithelial stem cells into functional dopaminergic neurons in 3D microfluidic cell culture.

  2015cited by this paper
• Microcirculation-on-a-Chip: A Microfluidic Platform for Assaying Blood- and Lymphatic-Vessel Permeability

  2015cited by this paper
• Engineering of a Biomimetic Pericyte-Covered 3D Microvascular Network

  2015cited by this paper
• A capillary-endothelium-mimetic microfluidic chip for the study of immune responses☆

  2015cited by this paper
• Microfluidic 3D cell culture: from tools to tissue models.

  2015cited by this paper
• A microfluidic bubble trap and oscillator.

  2015cited by this paper
• Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro

  2015cited by this paper
• An artificial blood vessel implanted three-dimensional microsystem for modeling transvascular migration of tumor cells.

  2015cited by this paper
• Organs-on-chips at the frontiers of drug discovery

  2015cited by this paper
• Pumpless microfluidic platform for drug testing on human skin equivalents.

  2015cited by this paper
• Adhesion patterns in the microvasculature are dependent on bifurcation angle.

  2015cited by this paper
• Endothelial progenitor cell recruitment in a microfluidic vascular model

  2015cited by this paper
• A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents.

  2015cited by this paper
• 3D liver models on a microplatform: well-defined culture, engineering of liver tissue and liver-on-a-chip.

  2015cited by this paper
• Liver sinusoid on a chip: Long‐term layered co‐culture of primary rat hepatocytes and endothelial cells in microfluidic platforms

  2015cited by this paper
• Microfluidic vascularized bone tissue model with hydroxyapatite-incorporated extracellular matrix.

  2015cited by this paper
• Microfluidically supported biochip design for culture of endothelial cell layers with improved perfusion conditions

  2015cited by this paper
• Three-Dimensional Blood-Brain Barrier Model for in vitro Studies of Neurovascular Pathology

  2015cited by this paper
• Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury.

  2014cited by this paper
• Human-on-chip for therapy development and fundamental science.

  2014cited by this paper
• Tissue-engineered microenvironment systems for modeling human vasculature

  2014cited by this paper
• A bioengineered array of 3D microvessels for vascular permeability assay.

  2014cited by this paper
• Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation

  2014cited by this paper
• A spatiotemporally defined in vitro microenvironment for controllable signal delivery and drug screening.

  2014cited by this paper
• Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone

  2014cited by this paper
• The importance of being a lumen

  2014cited by this paper
• A three-dimensional in vitro model of tumor cell intravasation.

  2014cited by this paper
• The present and future role of microfluidics in biomedical research

  2014cited by this paper
• Bone marrow–on–a–chip replicates hematopoietic niche physiology in vitro

  2014cited by this paper

• Multicellular, Biochemical, and Perfusion Effects on Vessel Network Morphogenesis in a Microfluidic Vasculature-on-a-Chip.

  2026cites this paper
• AI-powered image standardization in microphysiological system platforms

  2025cites this paper
• Evaluation of mitochondrial activity via cellular interactions between adrenal and neuronal cells in a microfluidic coculture device

  2025cites this paper
• Advances in Miniaturized Bioreactors: Bridging Biotechnology and Tissue Engineering for Enhanced Drug Development

  2025cites this paper
• Non-destructive luminescence and PET imaging to monitor tissue microenvironment in microphysiological systems during brain metastasis using dissociated cerebral organoids

  2025cites this paper
• Microfluidics as a Powerful Tool to Investigate Microvascular Dysfunction in Trauma Conditions: A Review of the State‐of‐the‐Art

  2024cites this paper
• Reendothelialization of Acellular Adipose Flaps under Mimetic Physiological Dynamic Conditions

  2024cites this paper
• Bioengineering vascularized liver tissue for biomedical research and application

  2024cites this paper
• Oxygen generating biomaterials at the forefront of regenerative medicine: advances in bone regeneration

  2024cites this paper
• Angiogenesis-on-a-chip coupled with single-cell RNA sequencing reveals spatially differential activations of autophagy along angiogenic sprouts

  2024cites this paper
• Nanoporous PEGDA ink for High-Resolution Additive Manufacturing of Scaffolds for Organ-on-a-Chip

  2024cites this paper
• Advances in the Model Structure of In Vitro Vascularized Organ-on-a-Chip

  2024cites this paper
• Design, fabrication, and application of bioengineering vascular networks based on microfluidic strategies.

  2024cites this paper
• 3D engineering of diseased blood vessels for integrative in vitro–in silico mechanobiology study

  2024cites this paper
• Evaluation of the Morphological and Biological Functions of Vascularized Microphysiological Systems with Supervised Machine Learning

  2023cites this paper
• Microfluidic vascular formation model for assessing angiogenic capacities of single islets

  2023cites this paper
• Coix Seed Oil ameliorates synovial angiogenesis in collagen-induced arthritis rats through inhibiting HIF-1 α / VEGF-A pathway via SIRT1

  2023cites this paper
• Tailoring biomaterials for biomimetic organs-on-chips.

  2023cites this paper
• Machine learning chained neural network analysis of oxygen transport amplifies the physiological relevance of vascularized microphysiological systems

  2023cites this paper
• A microfluidic platform integrating dynamic cell culture and dielectrophoretic manipulation for in situ assessment of endothelial cell mechanics.

  2023cites this paper
• A platform for modular assembly and feeding of micro-organoids on standard Petri dishes

  2023cites this paper
• Engineered Vasculature for Cancer Research and Regenerative Medicine

  2023cites this paper
• Building Blood Vessel Chips with Enhanced Physiological Relevance

  2023cites this paper
• Mechanical Evaluation of Hydrogel–Elastomer Interfaces Generated through Thiol–Ene Coupling

  2023cites this paper
• 3D printed microfluidics for cell biological applications

  2023cites this paper
• Vascularized Lung Cancer Model for Evaluating the Promoted Transport of Anticancer Drugs and Immune Cells in an Engineered Tumor Microenvironment

  2022cites this paper
• Engineering Approaches for Cardiac Organoid formation and their characterization.

  2022cites this paper
• Engineering Organ-on-a-Chip to Accelerate Translational Research

  2022cites this paper
• Proof-of-Concept Organ-on-Chip Study: Topical Cinnamaldehyde Exposure of Reconstructed Human Skin with Integrated Neopapillae Cultured under Dynamic Flow

  2022cites this paper
• Immunotherapy discovery on tumor organoid-on-a-chip platforms that recapitulate the tumor microenvironment.

  2022cites this paper
• Perfusable micro-vascularized 3D tissue array for high-throughput vascular phenotypic screening

  2022cites this paper
• Organ-On-A-Chip: A Survey of Technical Results and Problems

  2022cites this paper
• The vascular niche in next generation microphysiological systems.

  2021cites this paper
• Stromal cell identity modulates vascular morphogenesis in a microvasculature-on-a-chip platform.

  2021cites this paper
• Oxygen releasing materials: Towards addressing the hypoxia-related issues in tissue engineering.

  2021cites this paper
• Anchor‐IMPACT: A standardized microfluidic platform for high‐throughput antiangiogenic drug screening

  2021cites this paper
• Modeling 3D Human Tumor Lymphatic Vessel Network Using High‐Throughput Platform

  2021cites this paper
• Engineering New Microvascular Networks On‐Chip: Ingredients, Assembly, and Best Practices

  2021cites this paper
• Drawing Inspiration from Developmental Biology for Cardiac Tissue Engineers.

  2021cites this paper
• Tumor-on-a-chip: from bioinspired design to biomedical application

  2021cites this paper
• In Vitro Strategies to Vascularize 3D Physiologically Relevant Models

  2021cites this paper
• The potential of microfluidic devices in dermatology

  2021cites this paper
• Facilitating implementation of organs-on-chips by open platform technology

  2021cites this paper
• Systems and application biopsy

  2021cites this paper
• Recent Progress in Skin‐on‐a‐Chip Platforms

  2021cites this paper
• Advanced In Vitro Lung Models for Drug and Toxicity Screening: The Promising Role of Induced Pluripotent Stem Cells.

  2021cites this paper
• Biotechnology and Bioengineering: Volume 117, Number 11, November 2020

  2020cites this paper
• A Transparent Vessel-on-a-Chip Device for Hemodynamic Analysis and Early Diagnosis of Intracranial Aneurysms by CFD and PC-MRI.

  2020cites this paper
• 3D Microfluidic Platform and Tumor Vascular Mapping for Evaluating Anti-Angiogenic RNAi-Based Nanomedicine.

  2020cites this paper
• Newly emerged engineering of in vitro 3D tumor models using biomaterials for chemotherapy

  2020cites this paper
• Translational Roadmap for the Organs-on-a-Chip Industry toward Broad Adoption

  2020cites this paper
• Expanding sacrificially printed microfluidic channel-embedded paper devices for construction of volumetric tissue models in vitro

  2020cites this paper
• Fabrication of vascular smooth muscle-like tissues based on self-organization of circumferentially aligned cells in microengineered hydrogels.

  2020cites this paper
• Application of microfluidic technology in cancer research and therapy.

  2020cites this paper
• A new microfluidic model that allows monitoring of complex vascular structures and cell interactions in a 3D biological matrix.

  2020cites this paper
• High throughput physiological micro-models for in vitro pre-clinical drug testing: a review of engineering systems approaches

  2020cites this paper
• Microfluidics for Angiogenesis Research.

  2020cites this paper
• Biomaterials- and Microfluidics-Based Tissue Engineered 3D Models

  2020cites this paper
• Nitric Oxide and a Conditioned Medium Affect the Hematopoietic Development in a Microfluidic Mouse Embryonic Stem Cell/OP9 Co-Cultivation System

  2020cites this paper
• Recapitulating the Vasculature Using Organ-On-Chip Technology

  2020cites this paper
• The bioprinting roadmap

  2020cites this paper
• Robotic fluidic coupling and interrogation of multiple vascularized organ chips

  2020cites this paper
• Microfluidic skin chip with vasculature for recapitulating the immune response of the skin tissue

  2020cites this paper
• The interplay of signaling pathway in endothelial cells-Matrix stiffness dependency with targeted-therapeutic drugs.

  2019cites this paper
• Automated platform for cell selection and separation based on four-dimensional motility and matrix degradation.

  2019cites this paper
• Instrumented Microphysiological Systems for Real-Time Measurement and Manipulation of Cellular Electrochemical Processes

  2019cites this paper
• Integrated electrochemical measurement of endothelial permeability in a 3D hydrogel-based microfluidic vascular model.

  2019cites this paper
• Microfluidics-based skin irritation test using in vitro 3D angiogenesis platform

  2019cites this paper
• Imaging the Dynamic Interaction Between Sprouting Microvessels and the Extracellular Matrix

  2019cites this paper
• Tumor spheroid-on-a-chip: a standardized microfluidic culture platform for investigating tumor angiogenesis.

  2019cites this paper
• Recent progress in lab-on-a-chip for pharmaceutical analysis and pharmacological/toxicological test

  2019cites this paper
• Bioengineering 3D Cardiac Microtissues Using Bioassembly

  2019cites this paper
• Mimicking the Human Physiology with Microphysiological Systems (MPS)

  2019cites this paper
• Human Ocular Angiogenesis‐Inspired Vascular Models on an Injection‐Molded Microfluidic Chip

  2019cites this paper
• Microfluidic technologies for vasculature biomimicry.

  2019cites this paper
• Cell-Based Assays on Microfluidics for Drug Screening.

  2019cites this paper
• Engineering tumor vasculature on an injection-molded plastic array 3D culture (IMPACT) platform.

  2019cites this paper
• A robotic platform for fluidically-linked human body-on-chips experimentation

  2019cites this paper
• 3D brain angiogenesis model to reconstitute functional human blood–brain barrier in vitro

  2019cites this paper
• Recent Advances in Body-on-a-Chip Systems.

  2018cites this paper
• Influence of Culture Conditions on Cell Proliferation in a Microfluidic Channel

  2018cites this paper
• 3D brain angiogenesis model to reconstitute maturation of functional human blood-brain barrier in vitro

  2018cites this paper