Rosiglitazone improves pancreatic mitochondrial function in an animal model of dysglycemia: role of the insulin-like growth factor axis

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Endocrine

• Publication date

  2010-01-08

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s12020-009-9294-8PMID 20960268
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• In Utero and Lactational Exposure to Nicotine Alters the Intra-Ovarian IGF System in Adult Female Rats

  2009cited by this paper
• The role of insulin‐like growth factor‐I and its binding proteins in glucose homeostasis and type 2 diabetes

  2009cited by this paper
• Contribution of Impaired Myocardial Insulin Signaling to Mitochondrial Dysfunction and Oxidative Stress in the Heart

  2009cited by this paper
• Maternal nicotine exposure increases oxidative stress in the offspring.

  2008cited by this paper
• Low doses of insulin-like growth factor-I induce mitochondrial protection in aging rats.

  2008cited by this paper
• Fetal and Neonatal Nicotine Exposure in Wistar Rats Causes Progressive Pancreatic Mitochondrial Damage and Beta Cell Dysfunction

  2008cited by this paper
• Age-induced morphological, biochemical, and functional alterations in isolated mitochondria from murine skeletal muscle.

  2008cited by this paper
• Rosiglitazone counteracts palmitate-induced β-cell dysfunction by suppression of MAP kinase, inducible nitric oxide synthase and caspase 3 activities

  2008cited by this paper
• Rosiglitazone prevents diabetes by increasing beta‐cell mass in an animal model of type 2 diabetes characterized by reduced beta‐cell mass at birth

  2008cited by this paper
• Increased pancreatic beta-cell apoptosis following fetal and neonatal exposure to nicotine is mediated via the mitochondria.

  2008cited by this paper
• Augmented β cell loss and mitochondrial abnormalities in sucrose-fed GK rats

  2008cited by this paper
• Enhancement of muscle mitochondrial function by growth hormone.

  2008cited by this paper
• Rosiglitazone stimulates the release and synthesis of insulin by enhancing GLUT-2, glucokinase and BETA2/NeuroD expression.

  2008cited by this paper
• Activation of peroxisome proliferator-activated receptor gamma contributes to the survival of T lymphoma cells by affecting cellular metabolism.

  2007cited by this paper
• Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) by rosiglitazone suppresses components of the insulin-like growth factor regulatory system in vitro and in vivo.

  2007cited by this paper
• Defective IGF2 and IGF1R protein production in embryonic pancreas precedes beta cell mass anomaly in the Goto–Kakizaki rat model of type 2 diabetes

  2007cited by this paper
• Fetal and neonatal nicotine exposure and postnatal glucose homeostasis: identifying critical windows of exposure.

  2007cited by this paper
• Adipose Mitochondrial Biogenesis Is Suppressed in db/db and High-Fat Diet–Fed Mice and Improved by Rosiglitazone

  2007cited by this paper
• In beta-cells, mitochondria integrate and generate metabolic signals controlling insulin secretion.

  2006cited by this paper
• Total insulin and IGF-I resistance in pancreatic β cells causes overt diabetes

  2006cited by this paper
• Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes.

  2006cited by this paper
• The pancreatic beta-cell in human Type 2 diabetes.

  2006cited by this paper
• Autocrine anti‐apoptotic and proliferative effects of insulin in pancreatic β‐cells

  2006cited by this paper
• Resistance exercise training decreases oxidative damage to DNA and increases cytochrome oxidase activity in older adults.

  2005cited by this paper
• Plasma concentration of IGF-I is independently associated with insulin sensitivity in subjects with different degrees of glucose tolerance.

  2005cited by this paper
• A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine

  2005cited by this paper
• Fetal and neonatal exposure to nicotine in Wistar rats results in increased beta cell apoptosis at birth and postnatal endocrine and metabolic changes associated with type 2 diabetes

  2005cited by this paper
• Accumulation of mitochondrial DNA deletions is age, tissue and folate-dependent in rats.

  2005cited by this paper
• Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients

  2005cited by this paper
• Progressive Accumulation of Mitochondrial DNA Mutations and Decline in Mitochondrial Function Lead to β-Cell Failure*

  2005cited by this paper
• Antioxidant enzyme activity is up-regulated after unilateral resistance exercise training in older adults.

  2005cited by this paper
• Glucose-sensing mechanisms in pancreatic β-cells

  2005cited by this paper
• Mitochondrial Dysfunction and Type 2 Diabetes

  2005cited by this paper
• Insulin‐like growth factors and pancreas beta cells

  2004cited by this paper
• The Pathophysiology of Mitochondrial Cell Death

  2004cited by this paper
• Rationale, design and recruitment characteristics of a large, simple international trial of diabetes prevention: the DREAM trial

  2004cited by this paper
• Mitochondrial Biogenesis and Remodeling during Adipogenesis and in Response to the Insulin Sensitizer Rosiglitazone

  2003cited by this paper
• β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes

  2003cited by this paper
• Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes.

  2003cited by this paper
• β-cell–specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter β-cell mass

  2002cited by this paper
• beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass.

  2002cited by this paper
• Beta-cell mass dynamics in Zucker diabetic fatty rats. Rosiglitazone prevents the rise in net cell death.

  2001cited by this paper
• Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes.

  2000cited by this paper
• Impaired insulin secretion and β-cell loss in tissue-specific knockout mice with mitochondrial diabetes

  2000cited by this paper
• Transgenic mice overexpressing insulin-like growth factor-II in β cells develop type 2 diabetes

  2000cited by this paper
• Troglitazone prevents mitochondrial alterations, beta cell destruction, and diabetes in obese prediabetic rats.

  1999cited by this paper
• Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

  1999cited by this paper
• Application of Serum Nicotine and Plasma Cotinine Concentrations to Assessment of Nicotine Replacement in Light, Moderate, and Heavy Smokers Undergoing Transdermal Therapy

  1998cited by this paper
• Comparison of the Nicotine Pharmacokinetics of Nicoderm (Nicotine Transdermal System) and Half‐Hourly Cigarette Smoking

  1995cited by this paper
• Abbreviated title: Corresponding author:

  year unknowncited by this paper

• High content imaging of relative ATP levels for mitochondrial toxicity prediction in human induced pluripotent stem cell derived cardiomyocytes.

  2025cites this paper
• PPAR-γ Partial Agonists in Disease-Fate Decision with Special Reference to Cancer

  2022cites this paper
• Development of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases.

  2016cites this paper
• Interleukin-15 Modulates Adipose Tissue by Altering Mitochondrial Mass and Activity

  2014cites this paper
• Investigating the Role of Interleukin-15 in Modulating Adipose Tissue

  2014cites this paper
• The effect of smoking cessation pharmacotherapies on pancreatic beta cell function.

  2012cites this paper
• Low-level phenolic estrogen pollutants impair islet morphology and β-cell function in isolated rat islets.

  2012cites this paper
• Lowlevel Phenolic Estrogen Pollutants Impair Islets Morphology and βCells

  2012cites this paper
• Effect of combining rosiglitazone with either metformin or insulin on β‐cell mass and function in an animal model of Type 2 diabetes characterized by reduced β‐cell mass at birth

  2011cites this paper