Indoleamine 2,3-dioxygenase, immunosuppression and pregnancy.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Journal of Reproductive Immunology

• Publication date

  2002-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0165-0378(02)00040-2PMID 12385839
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cells Expressing Indoleamine 2,3-Dioxygenase Inhibit T Cell Responses1

  2002cited by this paper
• Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells.

  2002cited by this paper
• Indoleamine 2,3-dioxygenase expression in transplanted NOD Islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes.

  2002cited by this paper
• Functional expression of indoleamine 2,3-dioxygenase by murine CD8α+ dendritic cells

  2002cited by this paper
• Regulation of prostaglandin synthesis and cell adhesion by a tryptophan catabolizing enzyme

  2001cited by this paper
• Prevention of T cell–driven complement activation and inflammation by tryptophan catabolism during pregnancy

  2001cited by this paper
• CD40 Ligation Ablates the Tolerogenic Potential of Lymphoid Dendritic Cells1

  2001cited by this paper
• Antioxidants Inhibit Indoleamine 2,3-Dioxygenase in IFN-γ-Activated Human Macrophages: Posttranslational Regulation by Pyrrolidine Dithiocarbamate1

  2001cited by this paper
• Tryptophan catabolism prevents maternal T cells from activating lethal anti-fetal immune responses.

  2001cited by this paper
• Blockade of tryptophan catabolism prevents spontaneous tolerogenicity of liver allografts.

  2001cited by this paper
• IL-6 Inhibits the Tolerogenic Function of CD8α+ Dendritic Cells Expressing Indoleamine 2,3-Dioxygenase1

  2001cited by this paper
• Expression of indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase in early concepti.

  2001cited by this paper
• IFN-γ Inhibits Presentation of a Tumor/Self Peptide by CD8α− Dendritic Cells Via Potentiation of the CD8α+ Subset1

  2000cited by this paper
• Tumor Necrosis Factor-alpha and Lipopolysaccharide Enhance Interferon-Induced Antichlamydial Indoleamine Dioxygenase Activity Independently

  2000cited by this paper
• Regulation and Role of IFN-γ in the Innate Resistance to Infection with Chlamydia pneumoniae1

  2000cited by this paper
• Indoleamine 2,3-Dioxygenase Production by Human Dendritic Cells Results in the Inhibition of T Cell Proliferation

  2000cited by this paper
• Co-transplantation of donor-derived hepatocytes induces long-term tolerance to cardiac allografts in a rat model.

  2000cited by this paper
• INTERFACE: Lessons for T Cell Tolerance and Suppression

  2000cited by this paper
• Induction of indoleamine 2,3-dioxygenase in primary human macrophages by HIV-1

  2000cited by this paper
• Regulation and role of IFN-gamma in the innate resistance to infection with Chlamydia pneumoniae.

  2000cited by this paper
• Cytokine mediated regulation of interferon-gamma-induced IDO activation.

  1999cited by this paper
• Inducible anti-parasitic effector mechanisms in human uroepithelial cells: tryptophan degradation vs. NO production

  1999cited by this paper
• Inhibition of  T Cell Proliferation by Macrophage Tryptophan Catabolism

  1999cited by this paper
• Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation?

  1999cited by this paper
• Importance of L-tryptophan metabolism in trypanosomiasis.

  1999cited by this paper
• Prevention of allogeneic fetal rejection by tryptophan catabolism.

  1998cited by this paper
• Expression and Regulation of Interferon- γ-Induced Tryptophan Catabolism in Cultured Skin Fibroblasts

  1998cited by this paper
• Antigenic Cancer Cells Grow Progressively in Immune Hosts without Evidence for T Cell Exhaustion or Systemic Anergy

  1997cited by this paper
• Increased activity of the alpha 1(I) procollagen promoter in skin fibroblasts from patients with chronic eosinophilia-myalgia syndrome.

  1997cited by this paper
• Increased activity of the α1(I) procollagen promoter in skin fibroblasts from patients with chronic eosinophilia-myalgia syndrome

  1997cited by this paper
• Control of extracellular matrix degradation by interferon-gamma. The tryptophan connection.

  1996cited by this paper
• Control of Extracellular Matrix Degradation by Interferon-γ

  1996cited by this paper
• Relationship between interferon‐γ, indoleamine 2,3‐dioxygenase, and tryptophan catabolism

  1991cited by this paper
• Inhibition of phorbol ester-induced monocytic differentiation and c-fms gene expression by dexamethasone: potential involvement of arachidonic acid metabolites.

  1990cited by this paper

• Assessing the impact and risk of immunomodulatory compounds on pregnancy.

  2025cites this paper
• Development and Optimization of a Target Engagement Model of Brain IDO Inhibition for Alzheimer's Disease.

  2024cites this paper
• The role of the kynurenine pathway in cognitive functioning after stroke: A prospective clinical study.

  2023cites this paper
• The melatonin system is expressed in the ovine uterus: effect of the day of the oestrous cycle and undernutrition.

  2023cites this paper
• Accelerated kynurenine pathway downregulates immune activation in patients with axial spondyloarthritis.

  2023cites this paper
• On antigen‐specific signals, immune class regulation and energetics: Report III from the workshops on foundational concepts of immune regulation

  2023cites this paper
• Alternative pathway activation in pregnancy, a measured amount “complements” a successful pregnancy, too much results in adverse events

  2022cites this paper
• Harnessing the cyclization strategy for new drug discovery

  2022cites this paper
• Discovery of indoximod prodrugs and characterization of clinical candidate NLG802.

  2020cites this paper
• Molecules and Prostaglandins Related to Embryo Tolerance

  2020cites this paper
• N‐(3′,4′‐dimethoxycinnamonyl) anthranilic acid alleviates severe acute pancreatitis by inhibiting intestinal barrier dysfunction and NF‐κB activation

  2020cites this paper
• Prognostic signficance of tumor cell markers in diffuse large B-cell lymphoma with special emphasis on lymphoma localization

  2020cites this paper
• Role of Indoleamine-2,3-Dioxygenase Inhibitors in Salvage Therapy for Non-Muscle Invasive Bladder Cancer.

  2020cites this paper
• Enzyme indoleamine 2,3-dioxygenase 1: physiopathological implications during gestation in obesity conditions

  2020cites this paper
• ALTERATIONS OF THE LUNG ENVIRONMENT DURING A PNEUMONIA VIRUS OF MICE (PVM) INFECTION: STUDYING THE EFFECTS OF ALLERGEN INHALATION DURING AN UNDERLYING PVM INFECTION

  2019cites this paper
• T lymphocytes in the third trimester decidua in preeclampsia

  2019cites this paper
• Discovery of Clinical Candidate (1 R,4 r)-4-(( R)-2-(( S)-6-Fluoro-5 H-imidazo[5,1- a]isoindol-5-yl)-1-hydroxyethyl)cyclohexan-1-ol (Navoximod), a Potent and Selective Inhibitor of Indoleamine 2,3-Dioxygenase 1.

  2019cites this paper
• Mesenchymal Stem Cells Modulate the Immune System in Developing Therapeutic Interventions

  2019cites this paper
• Antioxidants in HIV in Africa: Supplements, Local Diet, and Education

  2018cites this paper
• New 4‐Amino‐1,2,3‐Triazole Inhibitors of Indoleamine 2,3‐Dioxygenase Form a Long‐Lived Complex with the Enzyme and Display Exquisite Cellular Potency

  2018cites this paper
• Characterization of human endometrial glandular epithelium in vitro and in vivo.

  2017cites this paper
• Managing epilepsy-associated depression: Serotonin enhancers or serotonin producers?

  2017cites this paper
• Nanomedicine and cancer immunotherapy: focus on indoleamine 2,3-dioxygenase inhibitors

  2017cites this paper
• Developmental Immunotoxicology Testing (DIT)

  2017cites this paper
• CXCL10 and IL‐6: Markers of two different forms of intra‐amniotic inflammation in preterm labor

  2017cites this paper
• Tryptophan and Serotonin Metabolism During Pregnancy Related to Season and Seasonality Status of Women

  2017cites this paper
• Immunopathology of the Female Reproductive Tract and Mammary Gland

  2017cites this paper
• Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults

  2017cites this paper
• Tumoral indoleamine 2, 3-dioxygenase 1 is regulated by monocytes and T lymphocytes collaboration in hepatocellular carcinoma

  2016cites this paper
• Immune tolerance properties of the testicular tissue as a viral sanctuary site in ART-treated HIV-infected adults

  2016cites this paper
• Forbearance of the Immune System during pregnancy: Fetal parasite takes an estrogenic way!

  2016cites this paper
• Perspective on a Modified Developmental and Reproductive Toxicity Testing Strategy for Cancer Immunotherapy

  2016cites this paper
• Interferon gamma-induced apoptosis of head and neck squamous cell carcinoma is connected to indoleamine-2,3-dioxygenase via mitochondrial and ER stress-associated pathways

  2016cites this paper
• Role of Indoleamine 2,3‐Dioxygenase and Tryptophan 2,3‐Dioxygenase in Patients with Recurrent Miscarriage

  2016cites this paper
• Propelling Immunotherapy Combinations Into the Clinic.

  2015cites this paper
• The Role of Indoleamine 2, 3-Dioxygenase in Immune Suppression and Autoimmunity

  2015cites this paper
• Chronic inflammation of the placenta: definition, classification, pathogenesis, and clinical significance.

  2015cites this paper
• Interferon-γ induces a tryptophan-selective amino acid transporter in human colonic epithelial cells and mouse dendritic cells.

  2015cites this paper
• Cyclic decidualization of the human endometrium in reproductive health and failure.

  2014cites this paper
• Conséquences de l'infection à cytomégalovirus sur le placenta humain

  2014cites this paper
• Indoleamine 2,3-dioxygenase levels at the normal and recurrent spontaneous abortion fetal–maternal interface

  2013cites this paper
• Possible role of the ‘IDO‐AhR axis’ in maternal‐foetal tolerance

  2013influential citation
• The Use of Nanocomposite Coatings with Various Physicochemical Properties in Tissue Engineering

  2013cites this paper
• Expression of Tryptophan 2,3-Dioxygenase and Production of Kynurenine Pathway Metabolites in Triple Transgenic Mice and Human Alzheimer's Disease Brain

  2013cites this paper
• Targeting the hypoxia-adenosinergic signaling pathway to improve the adoptive immunotherapy of cancer

  2013cites this paper
• Использование нанокомпозитных покрытий в технологиях культивирования мультипотентных мезенхимных стромальных клеток

  2013cites this paper
• tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells Regulation of indoleamine 2,3-dioxygenase and

  2013cites this paper
• Avaliação da influência da expressão da indoleamina 2,3-dioxigenase no ciclo celular de células placentárias e embrionárias murinas e de ratas em cultivo celular, frente à ação de hormônios e citocinas

  2012cites this paper
• Análise comparativa do mecanismo imunorregulador gerado pela indoleamina 2,3 dioxigenase (IDO) e interferon-gama (IFN-g) na interface materno-placentária entre mães que receberam transplante renal e mães saudáveis.

  2012cites this paper
• Tumoral indoleamine 2,3-dioxygenase expression predicts poor outcome in laryngeal squamous cell carcinoma

  2012cites this paper
• BORRELIDIN, A THREONYL-TRNA SYNTHETASE INHIBITOR, IS A POTENT IMMUNOSUPPRESSIVE AND ANTI-INFLAMMATORY AGENT

  2012cites this paper
• Immunosuppressive effect of progesterone on dendritic cells in mice.

  2011cites this paper
• Meeting report of the first conference of the International Placenta Stem Cell Society (IPLASS).

  2011cites this paper
• Differential actions of glycodelin-A on Th-1 and Th-2 cells: a paracrine mechanism that could produce the Th-2 dominant environment during pregnancy.

  2011cites this paper
• Indoleamine 2,3‐Dioxygenase and Tryptophan 2,3‐Dioxygenase

  2011cites this paper
• Mechanisms of selective immunosuppressive effects of indoleamine 2, 3-dioxygenase and borrelidin

  2011cites this paper
• Insights into Therapy: Tryptophan Oxidation and HIV Infection

  2010cites this paper
• On the role of placental Major Histocompatibility Complex and decidual leukocytes in implantation and pregnancy success using non-human primate models.

  2010cites this paper
• High expression of IMPACT protein promotes resistance to indoleamine 2,3‐dioxygenase‐induced cell death

  2010cites this paper
• Immunologie und Infektionskrankheiten

  2010cites this paper
• The oxidative stress-induced niacin sink (OSINS) model for HIV pathogenesis.

  2010cites this paper
• Mouse pancreatic islets are resistant to indoleamine 2,3 dioxygenase-induced general control nonderepressible-2 kinase stress pathway and maintain normal viability and function.

  2009cites this paper
• CD28: old dog, new tricks. CD28 in plasma cell/multiple myeloma biology.

  2009cites this paper
• The Immunology of Pregnancy

  2009cites this paper
• Protective adaptive immunity to Chlamydophila abortus infection and control of ovine enzootic abortion (OEA).

  2009cites this paper
• 10 – Sex Hormones, Pregnancy, and Immune Function

  2009cites this paper
• Identification of genetic variants in the human indoleamine 2,3-dioxygenase (IDO1) gene, which have altered enzyme activity

  2009cites this paper
• Interaction between dendritic cells and natural killer cells during pregnancy in mice

  2008cites this paper
• Inhibition of IFN-γ-Induced STAT1 Tyrosine Phosphorylation by Human CMV Is Mediated by SHP21

  2008cites this paper
• Dietary tryptophan helps to preserve tryptophan homeostasis in pigs suffering from lung inflammation.

  2008cites this paper
• The NrfH Cytochrome c Quinol Dehydrogenase

  2008cites this paper
• Inhibition of IFN-gamma-induced STAT1 tyrosine phosphorylation by human CMV is mediated by SHP2.

  2008cites this paper
• How does indoleamine 2,3-dioxygenase contribute to HIV-mediated immune dysregulation.

  2007cites this paper
• Mouse Models of Immunodeficiency

  2007cites this paper
• Immunosuppressive Effect of Tryptophan Metabolites in Composite Tissue Allotransplantation

  2007cites this paper
• Decidualization of the Human Endometrium: Mechanisms, Functions, and Clinical Perspectives

  2007cites this paper
• Substrate and cofactor requirements of indoleamine 2,3-dioxygenase in interferon-gamma-treated cells: utilization of oxygen rather than superoxide.

  2007cites this paper
• Indoleamine 2,3-dioxygenase in materno-fetal interaction.

  2007cites this paper
• Dendritic Cells: Key to Fetal Tolerance?1

  2007cites this paper
• Trophoblast Cells as Immune Regulators

  2006cites this paper
• CHAPTER 1 – Current Concepts of Infections of the Fetus and Newborn Infant

  2006cites this paper
• Estradiol in Locally Inhibiting CD 8 T Cells : Role of + Anti-Paternal CD 8 during Insemination Do Not Stimulate Paternal Antigen-Bearing Cells Transferred

  2006cites this paper
• Uterine natural killer cells: a specialized differentiation regulated by ovarian hormones

  2006cites this paper
• Decreased brain tryptophan availability as a partial determinant of post-partum blues.

  2006cites this paper
• NK cells and human pregnancy--an inflammatory view.

  2006cites this paper
• Genes regulating implantation and fetal development: a focus on mouse knockout models.

  2006cites this paper
• Paternal Antigen-Bearing Cells Transferred during Insemination Do Not Stimulate Anti-Paternal CD8+ T Cells: Role of Estradiol in Locally Inhibiting CD8+ T Cell Responses1

  2006cites this paper
• Nitration and Inactivation of IDO by Peroxynitrite1

  2006cites this paper
• Th1/Th2 Balance of the Implantation Site in Humans

  2006cites this paper
• Cytotrophoblast stem cell lines derived from human embryonic stem cells and their capacity to mimic invasive implantation events.

  2006cites this paper
• Linking Two Immuno-Suppressive Molecules: Indoleamine 2,3 Dioxygenase Can Modify HLA-G Cell-Surface Expression1

  2005cites this paper
• Indoleamine 2,3-dioxygenase: From tolerance during pregnancy to cancer

  2005cites this paper
• Glucose Availability Regulates IFN-γ Production and p70S6 Kinase Activation in CD8+ Effector T Cells1

  2005cites this paper
• Perinatal Immunotoxicity: Why Adult Exposure Assessment Fails to Predict Risk

  2005cites this paper
• Is the trophoblast an immune regulator? The role of Toll-like receptors during pregnancy.

  2005cites this paper
• Effect of arylformamidase (kynurenine formamidase) gene inactivation in mice on enzymatic activity, kynurenine pathway metabolites and phenotype.

  2005cites this paper
• PeroxynitriteNitration and Inactivation of IDO by

  2005cites this paper
• Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells.

  2005cites this paper
• Indoleamine 2,3-dioxygenase activity and L-tryptophan transport in human breast cancer cells.

  2004cites this paper
• Contribution à l'étude de l'immunosuppression et de l'induction de tolérance à l'allogreffe induite par des anticorps anti-CD28

  2004cites this paper