Changes in content and localization of proteins phosphorylated at tyrosine, serine and threonine residues during ram sperm capacitation and acrosome reaction.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Reproduction

• Publication date

  2009-04-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1530/REP-08-0280PMID 19151126
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Tyrosine phosphorylation of a 38-kDa capacitation-associated buffalo (Bubalus bubalis) sperm protein is induced by L-arginine and regulated through a cAMP/PKA-independent pathway.

  2007cited by this paper
• Tyrosine phosphorylation on capacitated human sperm tail detected by immunofluorescence correlates strongly with sperm-zona pellucida (ZP) binding but not with the ZP-induced acrosome reaction.

  2006cited by this paper
• Reactive oxygen species modulate independent protein phosphorylation pathways during human sperm capacitation.

  2006cited by this paper
• Signal transduction mechanisms involved in in vitro ram sperm capacitation.

  2006influential reference
• Positive role of reactive oxygen species in mammalian sperm capacitation: triggering and modulation of phosphorylation events.

  2006cited by this paper
• Evidence for the involvement of proline-directed serine/threonine phosphorylation in sperm capacitation.

  2006influential reference
• Dynamic quantification of the tyrosine phosphorylation of the sperm surface proteins during capacitation

  2006cited by this paper
• Immunohistochemical localization of sperm-preserving proteins in the ram reproductive tract.

  2006cited by this paper
• Protein tyrosine phosphorylation, hyperactivation and progesterone-induced acrosome reaction are enhanced in IVF media: an effect that is not associated with an increase in protein kinase A activation.

  2005cited by this paper
• Immunocytochemical localization and biochemical characterization of two seminal plasma proteins that protect ram spermatozoa against cold shock.

  2005cited by this paper
• The proacrosin binding protein, sp32, is tyrosine phosphorylated during capacitation of pig sperm.

  2005cited by this paper
• Tyrosine phosphorylation activates surface chaperones facilitating sperm-zona recognition

  2004cited by this paper
• Identification of goat sperm ecto‐cyclic AMP independent protein kinase substrate localized on sperm outer surface

  2004cited by this paper
• Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction

  2004cited by this paper
• Phosphorylation of the Arginine-X-X-(Serine/Threonine) motif in human sperm proteins during capacitation: modulation and protein kinase A dependency.

  2004influential reference
• Ram sperm selection by a dextran/swim-up procedure increases fertilization rates following intrauterine insemination in superovulated ewes.

  2004cited by this paper
• Rapid PKA‐catalysed phosphorylation of boar sperm proteins induced by the capacitating agent bicarbonate

  2004influential reference
• Various protein kinases regulate human sperm acrosome reaction and the associated phosphorylation of Tyr residues and of the Thr-Glu-Tyr motif.

  2004cited by this paper
• Mammalian fertilization.

  2004cited by this paper
• Protein phosphorylation in mammalian spermatozoa.

  2003cited by this paper
• Localization of Tyrosine Phosphorylated Proteins in Human Sperm and Relation to Capacitation and Zona Pellucida Binding1

  2003influential reference
• Phosphoproteome Analysis of Capacitated Human Sperm

  2003cited by this paper
• Hyperactivated motility in sperm.

  2003cited by this paper
• Specific order in the appearance of protein tyrosine phosphorylation patterns is functionally coordinated with dog sperm hyperactivation and capacitation.

  2003cited by this paper
• Analysis of the mechanism by which calcium negatively regulates the tyrosine phosphorylation cascade associated with sperm capacitation.

  2003cited by this paper
• Viability and protein phosphorylation patterns of boar spermatozoa agglutinated by treatment with a cell-permeable cyclic adenosine 3',5'-monophosphate analog.

  2003influential reference
• Phosphorylation of Protein Tyrosine Residues in Fresh and Cryopreserved Stallion Spermatozoa under Capacitating Conditions1

  2003cited by this paper
• A Differential Mechanism Is Involved During Heparin- and Cryopreservation-Induced Capacitation of Bovine Spermatozoa

  2003cited by this paper
• Protein serine and threonine phosphorylation, hyperactivation and acrosome reaction in in vitro capacitated hamster spermatozoa

  2002influential reference
• The extracellular signal-regulated kinase (ERK) pathway is involved in human sperm function and modulated by the superoxide anion.

  2002cited by this paper
• Identification of the major tyrosine phosphorylated protein of capacitated hamster spermatozoa as a homologue of mammalian sperm a kinase anchoring protein

  2002influential reference
• Seminal plasma proteins reduce protein tyrosine phosphorylation in the plasma membrane of cold‐shocked ram spermatozoa

  2002cited by this paper
• Different signal transduction pathways are involved during human sperm capacitation induced by biological and pharmacological agents.

  2002cited by this paper
• Novel signaling pathways involved in sperm acquisition of fertilizing capacity.

  2002cited by this paper
• Kinetic characterization of the changes in protein tyrosine phosphorylation of membranes, cytosolic Ca2+ concentration and viability in boar sperm populations selected by binding to oviductal epithelial cells.

  2001cited by this paper
• Capacitation dependent activation of tyrosine phosphorylation generates two sperm head plasma membrane proteins with high primary binding affinity for the zona pellucida

  2001cited by this paper
• The zona pellucida‐induced acrosome reaction of human spermatozoa involves extracellular signal‐regulated kinase activation

  2001cited by this paper
• A redox-regulated tyrosine phosphorylation cascade in rat spermatozoa.

  2001cited by this paper
• Capacitation Is Associated with Tyrosine Phosphorylation and Tyrosine Kinase-Like Activity of Pig Sperm Proteins1

  2001cited by this paper
• Protein Tyrosine Phosphorylation in Sperm During Gamete Interaction in the Mouse: The Influence of Glucose1

  2001cited by this paper
• Comparison of the capacitation-like state of cooled boar spermatozoa with true capacitation.

  2001cited by this paper
• Assessment of the acrosomal status of ram spermatozoa by RCA lectin-binding and partition in an aqueous two-phase system.

  2000cited by this paper
• The formation of a 1-5 phosphodiester linkage in the spontaneous breakdown of 5-phosphoribosyl-alpha-1-pyrophosphate.

  2000cited by this paper
• Stimulation of Ca(2+)-dependent exocytosis of the sperm acrosome by cAMP acting downstream of phospholipase A2.

  2000cited by this paper
• Role of tyrosine phosphorylation of flagellar proteins in hamster sperm hyperactivation.

  1999cited by this paper
• Modulation of sperm tail protein tyrosine phosphorylation by pentoxifylline and its correlation with hyperactivated motility.

  1999cited by this paper
• FSP95, a testis-specific 95-kilodalton fibrous sheath antigen that undergoes tyrosine phosphorylation in capacitated human spermatozoa.

  1999cited by this paper
• Involvement of protein serine and threonine phosphorylation in human sperm capacitation.

  1999influential reference
• Protein tyrosine phosphorylation during hyperactivated motility of cynomolgus monkey (Macaca fascicularis) spermatozoa.

  1999cited by this paper
• Protein kinases in mammalian sperm capacitation and the acrosome reaction.

  1999cited by this paper
• Regulation of protein phosphorylation during sperm capacitation.

  1998cited by this paper
• Extracellular signal-regulated kinases modulate capacitation of human spermatozoa.

  1998cited by this paper
• Regulation of protein tyrosine phosphorylation in boar sperm through a cAMP‐dependent pathway

  1998cited by this paper
• Regulation, localization, and anchoring of protein kinase A subunits during mouse sperm capacitation.

  1997cited by this paper
• Regulation of protein-tyrosine phosphorylation and human sperm capacitation by reactive oxygen derivatives.

  1997cited by this paper
• Control by phosphorylation.

  1996cited by this paper
• Viability of ram spermatozoa in relation to the abstinence period and successive ejaculations.

  1996cited by this paper
• A dextran swim-up procedure for separation of highly motile and viable ram spermatozoa from seminal plasma

  1996cited by this paper
• Hyperactivated motility in sperm.

  1996cited by this paper
• Human sperm activation during capacitation and acrosome reaction: role of calcium, protein phosphorylation and lipid remodelling pathways.

  1996cited by this paper
• Regulation of protein tyrosine phosphorylation in human sperm by a calcium/calmodulin-dependent mechanism: identification of A kinase anchor proteins as major substrates for tyrosine phosphorylation.

  1996influential reference
• Redox regulation of tyrosine phosphorylation in human spermatozoa and its role in the control of human sperm function.

  1995cited by this paper
• Serine/threonine protein phosphatases.

  1995cited by this paper
• Interaction of a tyrosine kinase from human sperm with the zona pellucida at fertilization.

  1995cited by this paper
• Phospholipase A2 activation and subsequent exocytosis in the Ca2+/ionophore-induced acrosome reaction of ram spermatozoa.

  1993cited by this paper
• The effects of phosphorylation on the structure and function of proteins.

  1993cited by this paper
• Role of membrane phosphotyrosine proteins in human spermatozoal function.

  1991cited by this paper
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  1990cited by this paper
• 95 kd sperm proteins bind ZP3 and serve as tyrosine kinase substrates in response to zona binding.

  1989cited by this paper
• Absence of active protein kinase C in ram spermatozoa.

  1988influential reference
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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• Bovine β-defensin 129 (BBD129) polymorphisms associated with differential posttranslational O-glycosylation and phosphorylation modifications perturb the sperm functions and their fertilizing potential.

  2025cites this paper
• Effect of 16h of rabbit sperm incubation on capacitation and heterologous in vitro fertilization.

  2025cites this paper
• In Vitro Exposure to the Endocrine-Disrupting Chemical Climbazole Impairs Human Sperm Motility, Hormonal Signalling, and Mitochondrial Activity

  2025cites this paper
• Quantitative phosphoproteomics analyses reveal the regulatory mechanisms related to frozen-thawed sperm capacitation and acrosome reaction in yak (Bos grunniens)

  2022cites this paper
• Beta-defensins as marker for male fertility: a comprehensive review

  2022cites this paper
• Analysis of amplification and association polymorphisms in the bovine beta-defensin 129 (BBD129) gene revealed its function in bull fertility

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• Amplification, copy number variation, expression and association of non-synonymous SNP of bovine beta-defensin 129 gene with distinct fertility of cattle bull

  2021cites this paper
• Effect of Heavy Metals on Tyrosine Kinases Signaling during Sperm Capacitation

  2021cites this paper
• cDNA cloning, expression and bioinformatical analysis of Tssk genes in tree shrews

  2021cites this paper
• Characterization of Human Spermatic Subpopulations by ConA-Binding Sites and Tyrosine Phosphorylation during in vitro Capacitation and Acrosome Reaction

  2021cites this paper
• Ouabain-induced activation of phospholipase C zeta and its contributions to bovine sperm capacitation

  2021cites this paper
• Unravelling how in vitro capacitation alters ram sperm chromatin before and after cryopreservation

  2020cites this paper
• Cryopreservation of ram sperm alters the dynamic changes associated with in vitro capacitation.

  2020cites this paper
• Different approaches for assessing sperm function

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• Lead and Cadmium exposure induces male reproductive dysfunction by modulating the expression profiles of apoptotic and survival signal proteins in tea-garden workers.

  2020cites this paper
• Changes in the Cellular Distribution of Tyrosine Phosphorylation and Its Relationship with the Acrosomal Exocytosis and Plasma Membrane Integrity during In Vitro Capacitation of Frozen/Thawed Bull Spermatozoa

  2020cites this paper
• Freezing–Thawing Procedures Remodel the Proteome of Ram Sperm before and after In Vitro Capacitation

  2019cites this paper
• Efecto de anandamida sobre la capacitación prematura de espermatozoides porcinos sometidos a congelación

  2019cites this paper
• Novel methods to detect capacitation-related changes in spermatozoa.

  2019cites this paper
• Epididymal and ejaculated sperm differ on their response to the cryopreservation and capacitation processes in mouflon (Ovis musimon)

  2019cites this paper
• Content and activity of the testis-specific isoform of angiotensin-converting enzyme are reduced in frozen-thawed bull spermatozoa.

  2018cites this paper
• Sperm capacitation pretreatment positively impacts bovine intracytoplasmic sperm injection

  2017cites this paper
• Testis‐specific isoform of angiotensin‐converting enzyme (tACE) is involved in the regulation of bovine sperm capacitation

  2017cites this paper
• Estrous sheep serum enables in vitro capacitation of ram spermatozoa while preventing caspase activation.

  2016cites this paper
• Seasonal dynamics in acrosome reaction induction in ram spermatozoa

  2016cites this paper
• Ram seminal plasma proteins contribute to sperm capacitation and modulate sperm-zona pellucida interaction.

  2015cites this paper
• Cannabis Smoke Causes Up-Regulation of Akt and Bax Protein in Subfertile Patients Sperm Cells

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• Protein tyrosine phosphorylation during capacitation in sperm of a rare red deer, Tarim wapiti (Cervus elaphus yarkandensis).

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• Embryotrophic Potential Of Novel And Candidate Oviductal Fluid Proteins Of Buffalo

  2014cites this paper
• Characterization of the cDNA and in vitro expression of the ram seminal plasma protein RSVP14.

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• Energy Management of Mature Mammalian Spermatozoa

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• Evolutionary conservation of mammalian sperm proteins associates with overall, not tyrosine, phosphorylation in human spermatozoa.

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• Elucidation of the Involvement of p14, a Sperm Protein during Maturation, Capacitation and Acrosome Reaction of Caprine Spermatozoa

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• Effect of sex sorting on CTC staining, actin cytoskeleton and tyrosine phosphorylation in bull and boar spermatozoa.

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• Methyl-parathion decreases sperm function and fertilization capacity after targeting spermatocytes and maturing spermatozoa.

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