Anaphylactic shock

Anaphylaxis is a life threatening hypersensitivity reaction that can cause shock. Epidemiology studies show anaphylaxis and anaphylactic shock is relatively rare, but its incidence is increasing. A review of the pathophysiology of anaphylaxis can provide insight into clinical decisions. Diagnosing anaphylaxis can be difficult as symptoms and history are not always obvious. Diagnostic guidelines provide an objective tool to assess for anaphylaxis. Early intervention during anaphylaxis may prevent development of shock. Management is focused on circulation support with epinephrine and IV fluids, and airway maintenance. Following an acute anaphylactic reaction, patients should be provided with a referral for follow up and educated on avoidance of triggers and use of epinephrine autoinjectors. immunologic and nonimmunologic biochemical pathways of anaphylaxis.

• Publication year

  2020

• Venue

  Reactions weekly

• Publication date

  2020-02-07

• Fields of study

  Not labeled

• Identifiers
  DOI 10.1007/s40278-020-85640-3
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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  2020cited by this paper
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  2005cited by this paper
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  2005cited by this paper
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  2005cited by this paper
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  2005cited by this paper
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  2005cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2003cited by this paper
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  2003cited by this paper
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  2002cited by this paper
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• Methylene blue as a rescue therapy for refractory nafamostat mesylate-induced anaphylaxis in a pediatric patient: a case report

  2025cites this paper
• Role of Platelet-Activating Factor in the Pathogenesis of Chronic Spontaneous Urticaria

  2024cites this paper
• Two adolescent cases presenting with anaphylaxis affecting cardiovascular system

  2023cites this paper
• Mast Cells as a Target—A Comprehensive Review of Recent Therapeutic Approaches

  2023cites this paper
• Epinephrine Administered in Anaphylaxis: The Evolution of 0.3 mg Dosage

  2023cites this paper
• Protective role of protease-activated receptor-2 in anaphylaxis model mice

  2023cites this paper
• Camrelizumab-induced anaphylactic shock in an esophageal squamous cell carcinoma patient: A case report and review of literature

  2022cites this paper
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